Cultura, identidad y resistencia: Elementos para un debate en torno al papel de la gestión cultural en la construcción de la identidad comunitaria

This paper aims to reflect about cultural management as a tool to resist the hegemonic dynamics of capitalism, and the role of the community-engaged art as instrument for creating community identity. At first, the concepts of hegemony and symbolic violence and their relationship with culture are analysed; then, the challenges and contradictions in the enlargement of artistic repertoires are discussed; finally, this paper focuses on the community construction of the symbolic, to think the political character of cultural management.El artículo tiene como objetivo reflexionar sobre el potencial de la gestión cultural como herramienta de resistencia a las dinámicas hegemónicas del capitalismo y el papel del arte colectivo como instrumento de construcción de identidad comunitaria. En primer lugar, se trabajan los conceptos de hegemonía y violencia simbólica y su relación con la cultura; en segundo lugar, se abordan los desafíos y contradicciones en la ampliación de los repertorios artísticos; y finalmente se reflexiona sobre la construcción comunitaria de lo simbólico, para repensar el carácter político de la gestión cultural

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe

Phenotypic and Genotypic Determination of Biofilm Formation in Shiga Toxin-Producing Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) O157:H7 is the most prevalent serotype associated with severe diseases worldwide. Biofilms by STEC O157:H7 constitute a high risk to public health and the food industry since they allow cross-contamination of surfaces and the consequent transmission to humans. This study aimed to detect the presence of adhesins genotypically and determine the ability to form biofilm and the curli expression in a collection of 30 O157:H7 strains from healthy cattle and human cases. The efa1, iha, fimCD, ehaA, lpfA1-3, and lpfA2-2 genes were detected in all strains; cah was frequently detected in strains isolated from humans (16/20), and agn43 was the least prevalent gene (3/30). All strains could form a biofilm, although those isolated from cattle were the most biofilm-formers. The curli-negative phenotype was the most prevalent phenotype observed at 37 °C and room temperature. The association between curli production and biofilm formation could not be determined, but the highest proportion of curli-positive strains at room temperature were strong biofilm-formers. These results highlight the possibility of the persistence of STEC O157:H7 in environmental conditions and food processing facilities, increasing the risk of contamination or infection.Fil: Cáceres, María Emilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Sanidad Animal y Medicina Preventiva; ArgentinaFil: Lavayen, Silvina. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Zotta, Claudio Marcelo. Dirección Nacional de Instituto de Investigación.Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"; ArgentinaFil: Montero, David. Universidad de Chile; ChileFil: Vidal, Roberto. Universidad de Chile; ChileFil: Etcheverría, Analía Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Padola, Nora Lía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentin

Where Brain, Body and World Collide

The production cross section of electrons from semileptonic decays of beauty hadrons was measured at mid-rapidity (|y| &lt; 0.8) in the transverse momentum range 1 &lt; pt &lt; 8 Gev/c with the ALICE experiment at the CERN LHC in pp collisions at a center of mass energy sqrt{s} = 7 TeV using an integrated luminosity of 2.2 nb^{-1}. Electrons from beauty hadron decays were selected based on the displacement of the decay vertex from the collision vertex. A perturbative QCD calculation agrees with the measurement within uncertainties. The data were extrapolated to the full phase space to determine the total cross section for the production of beauty quark-antiquark pairs

Manejo de situaciones especiales de las dislipidemias

No hay evidencia de alteraciones lipídicas específicas en niños con DM1. La dislipidemia debe ser considerada un factor de riesgo agregado, dadas las dificultades de lograr los objetivos de control glucémico. En los adolescentes, puede haber aumento de TG, en menor medida de c-LDL y disminución de c-HDL asociada a obesidad e insulinorresistencia.Fil: García, Alicia B.. No especifíca;Fil: Brites, Fernando Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Luongo, Ángela M.. No especifíca;Fil: Alvariñas, Jorge. No especifíca;Fil: Araujo, María I.. No especifíca;Fil: Belloso, Waldo Horacio. No especifíca;Fil: Bereziuk, Eulalio. No especifíca;Fil: Burlando, Guillermo. No especifíca;Fil: Carrera, Mabel. No especifíca;Fil: Cuniberti, Luis. No especifíca;Fil: Chioccone, Mónica. No especifíca;Fil: Doval, Hernán. No especifíca;Fil: Elbert, Alicia. No especifíca;Fil: Enrico, Teresa. No especifíca;Fil: Faingold, María C.. No especifíca;Fil: Ferraro, Mabel Catalina. No especifíca;Fil: Frechtel, Gustavo. No especifíca;Fil: Fuente, Graciela. No especifíca;Fil: González, Claudio. No especifíca;Fil: Lapertosa, Silvia. No especifíca;Fil: Livov, Alberto. No especifíca;Fil: López González, Eva. No especifíca;Fil: Mollerach, Julio. No especifíca;Fil: Mollerach, Marcelo. No especifíca;Fil: Mazza, Carmen. No especifíca;Fil: Montero, Julio. No especifíca;Fil: Paneth, Mónica Graciela. No especifíca;Fil: Portunato, Gabriela. No especifíca;Fil: Salzberg, Susana. No especifíca;Fil: Schraier, Silvio Daniel. No especifíca;Fil: Schreier, Laura Ester. No especifíca

Immunocompromised patients with acute respiratory distress syndrome : Secondary analysis of the LUNG SAFE database

The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiogenic shock were their most common risk factors for ARDS. Hospital mortality was higher in immunocompromised than in immunocompetent patients (52.4% vs 36.2%; p < 0.0001), despite similar severity of ARDS. Decisions regarding limiting life-sustaining measures were significantly more frequent in immunocompromised patients (27.1% vs 18.6%; p < 0.0001). Use of noninvasive ventilation (NIV) as first-line treatment was higher in immunocompromised patients (20.9% vs 15.9%; p = 0.0048), and immunodeficiency remained independently associated with the use of NIV after adjustment for confounders. Forty-eight percent of the patients treated with NIV were intubated, and their mortality was not different from that of the patients invasively ventilated ab initio. Conclusions: Immunosuppression is frequent in patients with ARDS, and infections are the main risk factors for ARDS in these immunocompromised patients. Their management differs from that of immunocompetent patients, particularly the greater use of NIV as first-line ventilation strategy. Compared with immunocompetent subjects, they have higher mortality regardless of ARDS severity as well as a higher frequency of limitation of life-sustaining measures. Nonetheless, nearly half of these patients survive to hospital discharge. Trial registration: ClinicalTrials.gov, NCT02010073. Registered on 12 December 2013