572 research outputs found

    Student\u27s Connectedness to Nature in Relation to Academic Major and Learning Style

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    The purpose of this research is to explore the relation between students’ connectedness to nature, academic major type and learning style. This study categorized student’s academic major into whether it was oriented toward business/advertising or natural resources/agriculture. Understanding students’ relationship with nature is important in a world that faces many environmental challenges. Studying academic major type and learning style provides references for chosen career paths and how students learn most efficiently. By running correlational analyses of these variables, more is understood about how connectedness to nature plays a role in students’ academic choices and learning preferences. Results showed a significant correlation between students’ score on the Nature Relatedness Scale and Academic Major Type. In particular, students orientated toward natural resources and agriculture displayed significantly higher scores on the Nature Relatedness Scale than those orientated toward business and advertising. This suggests that connectedness to nature is an indicator of how students assemble within the university. Future studies should look more thoroughly at connectedness to nature on the broad spectrum of academic majors

    Abilly – Le Foulon

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    Date de l'opération : 1991 (SD) Inventeur(s) : Richard-Millet Laure-Anne La découverte de mobilier archéologique en 1965 lors de travaux d'adduction d'eau, avait conduit à une rapide fouille de sauvetage indiquant la présence d'un habitat du Néolithique final. Une campagne de sondages a été réalisée en 1991 afin de retrouver l'emplacement du site. Sur quinze sondages ouverts, deux ont révélé du mobilier archéologique. Les vestiges très frais prouvent qu'ils n'avaient pas été déplacés. Le sond..

    Evaluation of natural language processing from emergency department computerized medical records for intra-hospital syndromic surveillance

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    <p>Abstract</p> <p>Background</p> <p>The identification of patients who pose an epidemic hazard when they are admitted to a health facility plays a role in preventing the risk of hospital acquired infection. An automated clinical decision support system to detect suspected cases, based on the principle of syndromic surveillance, is being developed at the University of Lyon's Hôpital de la Croix-Rousse. This tool will analyse structured data and narrative reports from computerized emergency department (ED) medical records. The first step consists of developing an application (UrgIndex) which automatically extracts and encodes information found in narrative reports. The purpose of the present article is to describe and evaluate this natural language processing system.</p> <p>Methods</p> <p>Narrative reports have to be pre-processed before utilizing the French-language medical multi-terminology indexer (ECMT) for standardized encoding. UrgIndex identifies and excludes syntagmas containing a negation and replaces non-standard terms (abbreviations, acronyms, spelling errors...). Then, the phrases are sent to the ECMT through an Internet connection. The indexer's reply, based on Extensible Markup Language, returns codes and literals corresponding to the concepts found in phrases. UrgIndex filters codes corresponding to suspected infections. Recall is defined as the number of relevant processed medical concepts divided by the number of concepts evaluated (coded manually by the medical epidemiologist). Precision is defined as the number of relevant processed concepts divided by the number of concepts proposed by UrgIndex. Recall and precision were assessed for respiratory and cutaneous syndromes.</p> <p>Results</p> <p>Evaluation of 1,674 processed medical concepts contained in 100 ED medical records (50 for respiratory syndromes and 50 for cutaneous syndromes) showed an overall recall of 85.8% (95% CI: 84.1-87.3). Recall varied from 84.5% for respiratory syndromes to 87.0% for cutaneous syndromes. The most frequent cause of lack of processing was non-recognition of the term by UrgIndex (9.7%). Overall precision was 79.1% (95% CI: 77.3-80.8). It varied from 81.4% for respiratory syndromes to 77.0% for cutaneous syndromes.</p> <p>Conclusions</p> <p>This study demonstrates the feasibility of and interest in developing an automated method for extracting and encoding medical concepts from ED narrative reports, the first step required for the detection of potentially infectious patients at epidemic risk.</p

    An Autopsy Case of Amyotrophic Lateral Sclerosis with Waldenström Macroglobulinemia and Anti-MAG Gammopathy

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    We report the case of a 71-year-old woman with typical signs of bulbar amyotrophic lateral sclerosis (ALS) associated with immunoglobulin M (IgM) monoclonal gammopathy and anti-MAG (myelin-associated glycoprotein) antibodies. This unusual association between ALS and anti-MAG antibodies has previously been reported in a single case. Our present case, at neuropathological examination, demonstrated no causative link between anti-MAG antibodies and ALS

    Martizay – Saint-Romain

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    Les campagnes de fouilles des années 1960 et 1970 avaient permis de mettre en évidence, sous les couches gallo-romaines, grâce à la présence de tessons de céramique, des niveaux du Néolithique et de l’âge du Bronze (Soubrier, Marquet 1979). Le mobilier a été revu récemment par Roland Irribarria (Inrap) et Anne Hauzeur (Paléotime) qui en ont confirmé le grand intérêt et l’âge néolithique moyen I. Nous avons pu d’autre part avoir accès au mobilier non tourné néolithique et protohistorique prove..

    Abilly – Bergeresse

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    Le site de Bergeresse à Abilly se trouve en rive droite de la Creuse, sur le versant est de la vallée, à quelques centaines de mètres en contrebas des formations d’altération du Turonien supérieur, livrant les dalles de silex exploitées au Néolithique final pour la fabrication des grandes lames sur livres de beurre. La fouille d’ateliers de débitage du silex a porté sur une surface de plus de 9 000 m2, dont 1 400 m2 ont été fouillés manuellement au cours de 7 campagnes de fouille programmée d..

    Phenotype Presentation and Molecular Diagnostic Yield in Non-5q Spinal Muscular Atrophy

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    BACKGROUND AND OBJECTIVES: Spinal muscular atrophy (SMA) is mainly caused by homozygous SMN1 gene deletions on 5q13. Non-5q SMA patients' series are lacking, and the diagnostic yield of next-generation sequencing (NGS) is largely unknown. The aim of this study was to describe the clinical and genetic landscape of non-5q SMA and evaluate the performance of neuropathy gene panels in these disorders. METHODS: Description of patients with non-5q SMA followed in the different neuromuscular reference centers in France as well as in London, United Kingdom. Patients without a genetic diagnosis had undergone at least a neuropathy or large neuromuscular gene panel. RESULTS: Seventy-one patients from 65 different families were included, mostly sporadic cases (60.6%). At presentation, 21 patients (29.6%) showed exclusive proximal weakness (P-SMA), 35 (49.3%) showed associated distal weakness (PD-SMA), and 15 (21.1%) a scapuloperoneal phenotype (SP-SMA). Thirty-two patients (45.1%) had a genetic diagnosis: BICD2 (n = 9), DYNC1H1 (n = 7), TRPV4 (n = 4), VCP, HSBP1, AR (n = 2), VRK1, DNAJB2, MORC2, ASAH1, HEXB, and unexpectedly, COL6A3 (n = 1). The genetic diagnostic yield was lowest in P-SMA (6/21, 28.6%) compared with PD-SMA (16/35, 45.7%) and SP-SMA (10/15, 66.7%). An earlier disease onset and a family history of the disease or consanguinity were independent predictors of a positive genetic diagnosis. Neuropathy gene panels were performed in 59 patients with a 32.2% diagnostic yield (19/59). In 13 additional patients, a genetic diagnosis was achieved through individual gene sequencing or an alternative neuromuscular NGS. DISCUSSION: Non-5q SMA is genetically heterogeneous, and neuropathy gene panels achieve a molecular diagnosis in one-third of the patients. The diagnostic yield can be increased by sequencing of other neuromuscular and neurometabolic genes. Nevertheless, there is an unmet need to cluster these patients to aid in the identification of new genes

    La filiacion y la fecundacion "in vitro"

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    Las tecnicas de reproduccion asistida no solo representan una solucion para ayudar a superar problemas de esterilidad, sino que su practica conlleva problemas eticos y juridicos. Esta Tesis analiza los problemas que plantea la fecundacion "in vitro", desde el punto de vista de la filiacion, para determinar la paternidad y maternidad cuando se utilizan los gametos de la pareja o de un tercero. Desde este punto de vista, se estudian la situacion juridica del tercero -llamado donante- y de las madres subrogadas, asi como las acciones de filiacion Tambien se examina la problematica que plantea la congelacion de semen y embriones, al poder un hombre engendrar un hijo despues de muerto. Entre las fuentes que se analizan estan los principales informes extranjeros que han estudiado la problematica de estas tecnicas, asi como el Informe especial de..

    Search for heavy resonances decaying to two Higgs bosons in final states containing four b quarks

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    A search is presented for narrow heavy resonances X decaying into pairs of Higgs bosons (H) in proton-proton collisions collected by the CMS experiment at the LHC at root s = 8 TeV. The data correspond to an integrated luminosity of 19.7 fb(-1). The search considers HH resonances with masses between 1 and 3 TeV, having final states of two b quark pairs. Each Higgs boson is produced with large momentum, and the hadronization products of the pair of b quarks can usually be reconstructed as single large jets. The background from multijet and t (t) over bar events is significantly reduced by applying requirements related to the flavor of the jet, its mass, and its substructure. The signal would be identified as a peak on top of the dijet invariant mass spectrum of the remaining background events. No evidence is observed for such a signal. Upper limits obtained at 95 confidence level for the product of the production cross section and branching fraction sigma(gg -> X) B(X -> HH -> b (b) over barb (b) over bar) range from 10 to 1.5 fb for the mass of X from 1.15 to 2.0 TeV, significantly extending previous searches. For a warped extra dimension theory with amass scale Lambda(R) = 1 TeV, the data exclude radion scalar masses between 1.15 and 1.55 TeV
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