44 research outputs found
Efecto De Las Tutorías En El Desempeño Académico En Estudiantes Del Ciclo Básico, Universidad De Santander-Colombia
En la Universidad de Santander (UDES), uno de los requisitos de admisión de estudiantes es la prueba de estado Saber 11, prueba enfocada a la valoración de las competencias en matemáticas, lectura crítica, sociales y ciudadanas, ciencias naturales e inglés, sin que el puntaje obtenido sea motivo de exclusión. Esto hace que los estudiantes de recién ingreso presenten niveles de desempeño heterogéneos en cada una de las competencias que evalúa la prueba. Se ha observado que estudiantes con niveles de desempeño bajos en lectura crítica y razonamiento cuantitativo, tiene más dificultad en la adaptación y nivelación académica. De igual forma es frecuente encontrar altos porcentajes de reprobación y cancelación de cursos durante el ciclo básico de formación, alcanzando hasta un 70% de reprobación y cancelación en el caso de cálculo diferencial. En este sentido, la UDES ha definido el Programa de Acompañamiento para el Ingreso y Permanencia Estudiantil PAIPE, donde se definen las estrategias para el fortalecimiento de competencias lectoras y escriturales (Programa Éxito Estudiantil) y el afianzamiento de presaberes básicos (programa Tutorías). El objetivo de este trabajo es evaluar el efecto del programa de tutorías en el desempeño académico de los estudiantes del ciclo básico de formación de UDES, mediante el análisis de su impacto en el rendimiento académico. Dicha evaluación, en esencia, responde al siguiente interrogante: ¿qué hubiese ocurrido con los beneficiarios del programa en caso de no haberse implementado? Los estudiantes de recién ingreso a la UDES, en los periodos analizados, muestran un desempeño heterogéneo en las pruebas genéricas Saber 11; en términos generales el 25% presentan un nivel de desempeño catalogado como riesgo alto, es decir que en las pruebas genéricas presentaron un desempeño bajo. La participación de los estudiantes en el programa, se ha incrementado, pasando de atender 112 estudiantes en el semestre B 2012, a 471 en el semestre B del 2015. La mayor participación, se ha dado en el área de ciencias naturales, mientras que en el área de matemáticas, pese a que es el área que representa mayor dificultad, la participación es menor. La cobertura de tutorías, dirigido especialmente a los estudiantes de primer semestre, se incrementó en un 74% aproximadamente en el año 2015, comparado con el 2014, siendo el 40% estudiantes de primer semestre. En el año 2015 el estudio mostró que efectivamente hay una asociación directa entre la participación en la tutoría y el desempeño académico; así se verificó que el 70% de los 1364 usuarios aprobaron los cursos para los que solicitaron el servicio de tutorías. También se evidenció la importancia de la relación entre la frecuencia de asistencia al servicio y el mejor resultado en el rendimiento final de los diferentes cursos. Para la sistematización de la información se ha desarrollado una plataforma ágil que permite el seguimiento del trabajo del estudiante y del tutor
The Accuracy of Blood Pressure Measurement by a Smartwatch and a Portable Health Device
Introduction: Hypertension is a leading cause of mortality. Proper blood pressure (BP) control can be achieved by lifestyle modification, pharmacotherapy, and frequent measurements. With the growing popularity of cuffless blood pressure monitors, it is important to independently validate their accuracy.
Objective: We evaluated two cuffless blood pressure monitors, The Everlast TR10 fitness watch and the BodiMetrics Performance Monitor, for their accuracy and precision in BP measurements.
Methods: Using a protocol derived from the ANSI/AAMI/ISO 2013 standard for evaluating automated sphygmomanometers, we measured the blood pressures of 85 patients recruited from the Thomas Jefferson University Hospital Preadmission Testing Center with two experimental devices and a validated automated sphygmomanometer cuff. We compared the mean absolute differences in measurements between the investigational and reference devices. Comparisons were analyzed with Spearman correlation and T-test, p\u3c0.05.
Results: The BodiMetrics Performance Monitor SBP measurements correlated well with the reference SBP measurements (ρ = 0.88, P \u3c 0.01), whereas the Everlast TR10 fitness watch did not (SBP: ρ = -0.19, P \u3c 0.01; DBP: ρ = -0.01, P \u3c 0.01). The BodiMetrics performance monitor reported a hypertensive BP (≥140 mm Hg) for 80% of the hypertensive reference SBP measurements, whereas the Everlast watch measured no hypertensive BP values for any of the hypertensive reference SBP or DBP measurements.
Discussion: The Everlast fitness watch and BodiMetrics Performance Monitor are not accurate enough to use for blood pressure monitoring. Use of these devices will likely result in misclassifying patients with hypertension as normotensive, which is a public health concern
A three-step approach to patients with suspected acute diverticulitis in the emergency department: An interdisciplinary algorithm proposal
Patients with acute abdominal pain due to acute colonic diverticulitis are a frequent cause of hospital admission. Diverticuar disease increases with age. In Western populations, diverticular disease is diagnosed in 50% individuals over 70 years and 80% over 85 years of age. The identification of patients with acute diverticulitis is a considerable challenge, since numerous other acute abdominal conditions mimic its clinical characteristics. Another problem is the atypical presentation in older patients. A high index of suspicion in the setting of a compatible history and physical examination serves as the cornerstone of early diagnosis. The purpose of this review is to underline the importance of an intimately integrate multidisciplinary approach between emergency physicians, radiologists and surgeons
Accuracy of Vital Signs Measurements by a Smartwatch and a Portable Health Device: Validation Study.
BACKGROUND: New consumer health devices are being developed to easily monitor multiple physiological parameters on a regular basis. Many of these vital sign measurement devices have yet to be formally studied in a clinical setting but have already spread widely throughout the consumer market.
OBJECTIVE: The aim of this study was to investigate the accuracy and precision of heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and oxygen saturation (SpO2) measurements of 2 novel all-in-one monitoring devices, the BodiMetrics Performance Monitor and the Everlast smartwatch.
METHODS: We enrolled 127 patients (\u3e18 years) from the Thomas Jefferson University Hospital Preadmission Testing Center. SBP and HR were measured by both investigational devices. In addition, the Everlast watch was utilized to measure DBP, and the BodiMetrics Performance Monitor was utilized to measure SpO2. After 5 min of quiet sitting, four hospital-grade standard and three investigational vital sign measurements were taken, with 60 seconds in between each measurement. The reference vital sign measurements were calculated by determining the average of the two standard measurements that bounded each investigational measurement. Using this method, we determined three comparison pairs for each investigational device in each subject. After excluding data from 42 individuals because of excessive variation in sequential standard measurements per prespecified dropping rules, data from 85 subjects were used for final analysis.
RESULTS: Of 85 participants, 36 (42%) were women, and the mean age was 53 (SD 21) years. The accuracy guidelines were only met for the HR measurements in both devices. SBP measurements deviated 16.9 (SD 13.5) mm Hg and 5.3 (SD 4.7) mm Hg from the reference values for the Everlast and BodiMetrics devices, respectively. The mean absolute difference in DBP measurements for the Everlast smartwatch was 8.3 (SD 6.1) mm Hg. The mean absolute difference between BodiMetrics and reference SpO2 measurements was 3.02%.
CONCLUSIONS: Both devices we investigated met accuracy guidelines for HR measurements, but they failed to meet the predefined accuracy guidelines for other vital sign measurements. Continued sale of consumer physiological monitors without prior validation and approval procedures is a public health concern
Development of the Gastrointestinal Dysfunction Score (GIDS) for critically ill patients – A prospective multicenter observational study (iSOFA study)
Background & aims: To develop a five grade score (0–4 points) for the assessment of gastrointestinal (GI) dysfunction in adult critically ill patients. Methods: This prospective multicenter observational study enrolled consecutive adult patients admitted to 11 intensive care units in nine countries. At all sites, daily clinical data with emphasis on GI clinical symptoms were collected and intra-abdominal pressure measured. In five out of 11 sites, the biomarkers citrulline and intestinal fatty acid-binding protein (I-FABP) were measured additionally. Cox models with time-dependent scores were used to analyze associations with 28- and 90-day mortality. The models were estimated with stratification for study center. Results: We included 540 patients (224 with biomarker measurements) with median age of 65 years (range 18–94), the Simplified Acute Physiology Score II score of 38 (interquartile range 26–53) points, and Sequential Organ Failure Assessment (SOFA) score of 6 (interquartile range 3–9) points at admission. Median ICU length of stay was 3 (interquartile range 1–6) days and 90-day mortality 18.9%. A new five grade Gastrointestinal Dysfunction Score (GIDS) was developed based on the rationale of the previously developed Acute GI Injury (AGI) grading. Citrulline and I-FABP did not prove their potential for scoring of GI dysfunction in critically ill. GIDS was independently associated with 28- and 90-day mortality when added to SOFA total score (HR 1.40; 95%CI 1.07–1.84 and HR 1.40; 95%CI 1.02–1.79, respectively) or to a model containing all SOFA subscores (HR 1.48; 95%CI 1.13–1.92 and HR 1.47; 95%CI 1.15–1.87, respectively), improving predictive power of SOFA score in all analyses. Conclusions: The newly developed GIDS is additive to SOFA score in prediction of 28- and 90-day mortality. The clinical usefulness of this score should be validated prospectively. Trial registration: NCT02613000, retrospectively registered 24 November 2015.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genome-wide significant loci comprising 49 distinct association signals. Effect sizes were largest for stage 3/4 disease, driven by ovarian endometriosis. Identified signals explained up to 5.01% of disease variance and regulated expression or methylation of genes in endometrium and blood, many of which were associated with pain perception/maintenance (SRP14/BMF, GDAP1, MLLT10, BSN and NGF). We observed significant genetic correlations between endometriosis and 11 pain conditions, including migraine, back and multisite chronic pain (MCP), as well as inflammatory conditions, including asthma and osteoarthritis. Multitrait genetic analyses identified substantial sharing of variants associated with endometriosis and MCP/migraine. Targeted investigations of genetically regulated mechanisms shared between endometriosis and other pain conditions are needed to aid the development of new treatments and facilitate early symptomatic intervention
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genome-wide significant loci comprising 49 distinct association signals. Effect sizes were largest for stage 3/4 disease, driven by ovarian endometriosis. Identified signals explained up to 5.01% of disease variance and regulated expression or methylation of genes in endometrium and blood, many of which were associated with pain perception/maintenance (SRP14/BMF, GDAP1, MLLT10, BSN and NGF). We observed significant genetic correlations between endometriosis and 11 pain conditions, including migraine, back and multisite chronic pain (MCP), as well as inflammatory conditions, including asthma and osteoarthritis. Multitrait genetic analyses identified substantial sharing of variants associated with endometriosis and MCP/migraine. Targeted investigations of genetically regulated mechanisms shared between endometriosis and other pain conditions are needed to aid the development of new treatments and facilitate early symptomatic intervention
New genetic loci link adipose and insulin biology to body fat distribution.
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms