Design of a Secure Architecture for Last Mile Communication in Smart Grid Systems

AbstractEver increasing need of electricity has paved the need for Smart Grids. Smart Meters, digitalized networks and fault tolerant systems are the basic infrastructure which supports Smart Grid. Security in Smart Grid has become a major concern in the present scenario. In this paper we have proposed security architecture at the last mile distribution in Home Area Networks. A Secure communication architecture has been modeled which focuses on secure data transmission between the Smart Meters at home and Central Gateway at the utility centre. Hybrid Encryption algorithms and Digital Signature has been used to provide data integrity. The strength of the model has been verified with the help of an attacker and the model is found to resist attacks. The Encryption time and Decryption time of the cyptostack is lower when compared with other encryption algorithms

Aerometric monitoring system for pollution control

Air quality monitoring and analysis is needed in order to provide decision makers with reliable information about the pollution situation so that they can take appropriate measures to mitigate or prevent negative impacts whenever there is need. World Health Organization (WHO) has recently announced that air pollution is carcinogenic to humans. The results from the reviewed studies point in the same direction: the risk of developing lung cancer hss significantly increased in people exposed to air pollution. This finding elevates the urgency to create awareness among common people about the air, both outdoors and indoors. In our project "Aerometric Monitoring System for Pollution Control”, we use a device that consists of a cluster of sensors that are used to sense atmospheric characteristics continuously. Atmospheric characteristics include Temperature, Humidity, Gas index indicating presence of poisonous gases etc. Several such devices can be deployed in places where we need to estimate air pollution. This covers public domains like bus stands, railway stations, junctions etc. and private domains like households, small scale industries and so on. The aggregated data collected by these devices are uploaded to the Internet using IoT platform by establishing a connection. The data is then displayed on the IoT platform along with various graphical representations. This enables the public to access the data anywhere, any time

Newborn friendly thermometry – Comparative study of body temperature with an infrared versus digital thermometer

Background: Accurate measurement of body temperature is of great importance in day to day neonatology practice. One touch infraredthermometry is safe, accurate, and easy to use. Objective: We aimed at comparing infrared forehead thermometer with an axillary digitalthermometer to assess the accuracy. Methods: Axillary and forehead temperatures were measured simultaneously in normal newbornbabies using digital and infrared thermometers respectively at a tertiary level teaching hospital in northern Kerala, India and the meantemperature measured by these two methods were compared. Those babies with fever or admitted at Neonatal Intensive Care Unit werenot included in the study. Results: Totally, 193 newborns were included in the study with the mean birth weight of 2600±400 g. Therewas no significant difference in temperature measured by digital and infrared thermometers (97.74±0.91°F vs. 97.81±0.89°F, p=0.44).There was a significant positive correlation between axillary and forehead temperature (r=0.94) and mean difference between two readingswas 0.07±0.25°F (p=0.11). Conclusion: Infrared forehead thermometry is as reliable and accurate as axillary digital thermometry. Thus,infrared forehead thermometry can be used in clinical practice, especially in neonatal and postnatal wards where ease of use and speed ofobtaining the temperature readings are important

Selective isomer emission via funneling of exciton polaritons

Polaritons in organic systems has shown the potential to modify chemical properties and to mediate long-range energy transfer between individual chromophores, among other capabilities. Here, we demonstrate that strong coupling and formation of organic exciton-polaritons can be used to selectively tune the isomer emission of organic molecules. By taking advantage of their delocalized and hybrid character, polaritons emerging in the strong coupling regime open a new relaxation pathway that allows for an efficient funneling of the excitation between the molecular isomers. We implement this by strong coupling to trans-DCS (E-4-dimethylamino-4′cyanostilbene) molecules, which present two isomers in different amounts when immersed in a polymer matrix. Thanks to this new relaxation pathway, the photoexcitation that is first shared by the common polaritonic mode is then selectively funneled to the excited states of one of the isomers, recognizing pure emission from the isomeric states that do not contribute to emission under normal conditionsThis work was supported by the Department of Energy, USA under DOE-47851-00- 01. We also acknowledge the use of the nanofabrication and imaging facility at ASRC, CUNY. J.F. and F.J.G.-V. acknowledge financial support from the European Research Council through grant ERC-2016-StG-71487

Studies on Sexual Behavior During COVID-19 Pandemic: A Bibliometric Analysis

Sexual relations suffered from a drastic change because of the pandemic of the COVID-19 and its controlling measures. We performed a bibliometric review of articles conducted on sexual behavior through this COVID-19 pandemic. We performed a search in the Scopus database on August 14, 2021. The search was carried out by the mentioned search terms: “sex* act*” OR “Sex* Behav*” AND “COVID-19.” A total of 230 published articles was identified in the Scopus database, out of which 130 research works were funded and 23.91% (n = 55) articles had international collaborations. R Stephenson published the highest number of papers (n = 4) whilst SK Kar had the maximum number of citations (n = 39) and the highest number of citations per article (13). Universidade de São Paulo and the University of California were the most productive organizations whilst the USA outnumbered the other countries. Sexually Transmitted Infections (n = 13) and Elsevier (61) published the highest number of papers as a journal and publisher, respectively. It is the first bibliometric review on studies that assessed impact of the COVID-19 pandemic on human sexual activities during which identified that more than half of the articles were funded which is a promising sign for the researchers from this field and for those who are keen to work in this field

The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice

Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target. The plant polyphenol Curcumin has been proposed for dietary prevention of cancer. We therefore examined its effects on the human breast cancer cell line MDA-MB-231 in vitro and in a mouse metastasis model. Curcumin strongly induces apoptosis in MDA- MB- 231 cells in correlation with reduced activation of the survival pathway NF kappa B, as a consequence of diminished I kappa B and p65 phosphorylation. Curcumin also reduces the expression of major matrix metalloproteinases (MMPs) due to reduced NF kappa B activity and transcriptional downregulation of AP-1. NF kappa B/p65 silencing is sufficient to downregulate c-jun and MMP expression. Reduced NF kappa B/AP-1 activity and MMP expression lead to diminished invasion through a reconstituted basement membrane and to a significantly lower number of lung metastases in immunodeficient mice after intercardiac injection of 231 cells (p=0.0035). 68% of Curcumin treated but only 17% of untreated animals showed no or very few lung metastases, most likely as a consequence of down-regulation of NF kappa B/AP-1 dependent MMP expression and direct apoptotic effects on circulating tumor cells but not on established metastases. Dietary chemoprevention of metastases appears therefore feasible. Copyright (c) 2007 S. Karger AG, Basel

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks