805 research outputs found

    Prospectus, November 3, 1969

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    STUDENT GOVERNMENT: NEW OFFICERS TELL PLANS FOR COMING SCHOOL YEAR; Knows Line?; Parkland College Makes History; Farris Plans Spending; Here\u27s Your Chance!; Support Our Astronauts; Carol Scherer Feels PC Has Lots To Offer; Laurel and Hardy; Dance November 7; Record Reviews; Journalism Workshop Here Nov. 8; Unusual Moments on Campus; PC Students: Here\u27s Where It Happens; I-Beam, for the Fashion Minded; Letters To The Editor; First Yearbook To Arrive in Spring; Moratorium Sparks Interest; Vets Hold \u27Walk\u27; Casino Night Profitable; Russell Appeals Baseball Ruling; Ikes, Bandits Lead in I.M.; Two Out for X-Country; Parkland Wrestling Beginshttps://spark.parkland.edu/prospectus_1969/1001/thumbnail.jp

    Hidradenoma Papilliferum Occurring on the Nasal Skin

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    Hidradenoma papilliferum is a rare benign neoplasm that usually occurs in the female anogenital area. We present a 43-year-old female with a non-anogenital (ectopic) hidradenoma papilliferum on her nose. The patient had had a skin-colored subcutaneous nodule on her nose for 7 years. The histopathological findings showed variously shaped cystic spaces in the tumor. And the lumina were surrounded by a single or double layer of cell which showed decapitation secretion. In the English dermatological literature, only one case of ectopic hidradenoma papilliferum arising in nasal skin has been reported. Hence we suggest hidradenoma papilliferum occurring on the nasal skin is a peculiar and interesting event

    Stress overshoot in a simple yield stress fluid: an extensive study combining rheology and velocimetry

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    We report a large amount of experimental data on the stress overshoot phenomenon which takes place during start-up shear flows in a simple yield stress fluid, namely a carbopol microgel. A combination of classical rheological measurements and ultrasonic velocimetry makes it possible to get physical insights on the transient dynamics of both the stress σ(t)\sigma(t) and the velocity field across the gap of a rough cylindrical Couette cell during the start-up of shear under an applied shear rate γ˙\dot\gamma. (i) At small strains (γ<1\gamma <1), σ(t)\sigma(t) increases linearly and the microgel undergoes homogeneous deformation. (ii) At a time tmt_m, the stress reaches a maximum value σm\sigma_m which corresponds to the failure of the microgel and to the nucleation of a thin lubrication layer at the moving wall. (iii) The microgel then experiences a strong elastic recoil and enters a regime of total wall slip while the stress slowly decreases. (iv) Total wall slip gives way to a transient shear-banding phenomenon, which occurs on timescales much longer than that of the stress overshoot and has been described elsewhere [Divoux \textit{et al., Phys. Rev. Lett.}, 2010, \textbf{104}, 208301]. This whole sequence is very robust to concentration changes in the explored range (0.5C30.5 \le C \le 3% w/w). We further demonstrate that the maximum stress σm\sigma_m and the corresponding strain γm=γ˙tm\gamma_m=\dot\gamma t_m both depend on the applied shear rate γ˙\dot \gamma and on the waiting time twt_w between preshear and shear start-up: they remain roughly constant as long as γ˙\dot\gamma is smaller than some critical shear rate γ˙w1/tw\dot\gamma_w\sim 1/t_w and they increase as weak power laws of γ˙\dot \gamma for γ˙>γ˙w\dot\gamma> \dot\gamma_w [...].Comment: 18 pages, 14 figures, accepted for publication in Soft Matte

    Resting state network mapping in individuals using deep learning

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    INTRODUCTION: Resting state functional MRI (RS-fMRI) is currently used in numerous clinical and research settings. The localization of resting state networks (RSNs) has been utilized in applications ranging from group analysis of neurodegenerative diseases to individual network mapping for pre-surgical planning of tumor resections. Reproducibility of these results has been shown to require a substantial amount of high-quality data, which is not often available in clinical or research settings. METHODS: In this work, we report voxelwise mapping of a standard set of RSNs using a novel deep 3D convolutional neural network (3DCNN). The 3DCNN was trained on publicly available functional MRI data acquired in RESULTS: Our results indicate this method can be applied in individual subjects and is highly resistant to both noisy data and fewer RS-fMRI time points than are typically acquired. Further, our results show core regions within each network that exhibit high average probability and low STD. DISCUSSION: The 3DCNN algorithm can generate individual RSN localization maps, which are necessary for clinical applications. The similarity between 3DCNN mapping results and task-based fMRI responses supports the association of specific functional tasks with RSNs

    Quantitative imaging of concentrated suspensions under flow

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    We review recent advances in imaging the flow of concentrated suspensions, focussing on the use of confocal microscopy to obtain time-resolved information on the single-particle level in these systems. After motivating the need for quantitative (confocal) imaging in suspension rheology, we briefly describe the particles, sample environments, microscopy tools and analysis algorithms needed to perform this kind of experiments. The second part of the review focusses on microscopic aspects of the flow of concentrated model hard-sphere-like suspensions, and the relation to non-linear rheological phenomena such as yielding, shear localization, wall slip and shear-induced ordering. Both Brownian and non-Brownian systems will be described. We show how quantitative imaging can improve our understanding of the connection between microscopic dynamics and bulk flow.Comment: Review on imaging hard-sphere suspensions, incl summary of methodology. Submitted for special volume 'High Solid Dispersions' ed. M. Cloitre, Vol. xx of 'Advances and Polymer Science' (Springer, Berlin, 2009); 22 pages, 16 fig

    Recent cadmium exposure among male partners may affect oocyte fertilization during in vitro fertilization (IVF)

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    We recently reported evidence suggesting associations between urine cadmium concentrations, reflecting long-term exposure, measured in 25 female patients (relative risk = 1.41, P = 0.412) and 15 of their male partners (relative risk = 0.19, P = 0.097) and oocyte fertilization in vitro. Blood cadmium concentrations reflect more recent exposure. We here incorporate those measures into our prior data set and employ multivariable log-binomial regression models to generate hypotheses concerning the relative effects of long-term and recent cadmium exposure on oocyte fertilization in vitro. No association is indicated for blood cadmium from women and oocyte fertilization, adjusted for urine cadmium and creatinine, blood lead and mercury, age, race/ethnicity and cigarette smoking (relative risk = 0.88, P = 0.828). However, we suggest an inverse adjusted association between blood cadmium from men and oocyte fertilization (relative risk = 0.66, P = 0.143). These results suggest that consideration of long-term and recent exposures are both important for assessing the effect of partner cadmium levels on oocyte fertilization in vitro

    A Literature Review of Social and Economic Leader-Member Exchange

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    Leader–member exchange (LMX) research has increasingly relied upon the social exchange theory (SET) as a theoretical foundation, but the dominating way of measuring LMX has not followed this theoretical development (Gottfredson et al., 2020). With the aim of developing a measure that more coherently reflects SET, Kuvaas et al. (2012) conceptualized LMX as two qualitatively different relationships, labeled economic LMX and social LMX. Since the most applied LMX measures are under scrutiny for not being sufficiently grounded in theory (Gottfredson et al., 2020), it may be especially important to expose alternative measures. Therefore, we provide a comprehensive review of the research to date applying a two-dimensional approach to LMX, while also adding to interpretation and suggestions for how we can progress the field even further.publishedVersio

    MassBuilt: effectiveness of an apprenticeship site-based smoking cessation intervention for unionized building trades workers

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    Blue-collar workers are difficult to reach and less likely to successfully quit smoking. The objective of this study was to test a training site-based smoking cessation intervention. This study is a randomized-controlled trial of a smoking cessation intervention that integrated occupational health concerns and was delivered in collaboration with unions to apprentices at 10 sites (n = 1,213). We evaluated smoking cessation at 1 and 6 months post-intervention. The baseline prevalence of smoking was 41%. We observed significantly higher quit rates in the intervention versus control group (26% vs. 16.8%; p = 0.014) 1 month after the intervention. However, the effects diminished over time so that the difference in quit rate was not significant at 6 month post-intervention (9% vs. 7.2%; p = 0.48). Intervention group members nevertheless reported a significant decrease in smoking intensity (OR = 3.13; 95% CI: 1.55–6.31) at 6 months post-intervention, compared to controls. The study demonstrates the feasibility of delivering an intervention through union apprentice programs. Furthermore, the notably better 1-month quit rate results among intervention members and the greater decrease in smoking intensity among intervention members who continued to smoke underscore the need to develop strategies to help reduce relapse among blue-collar workers who quit smoking

    Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring

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    Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to bisphenol A (BPA). Moreover, BPA structural analogues (e.g. BPS, BPF, BPAF), used as BPA replacements, are being increasingly detected in human biological matrices. BPA and some of its analogues are classified as endocrine disruptors suspected of contributing to adverse health outcomes such as altered reproduction and neurodevelopment, obesity, and metabolic disorders among other developmental and chronic impairments. One of the aims of the H2020 European Human Biomonitoring Initiative (HBM4EU) is the implementation of effect biomarkers at large scales in future HBM studies in a systematic and standardized way, in order to complement exposure data with mechanistically-based biomarkers of early adverse effects. This review aimed to identify and prioritize existing biomarkers of effect for BPA, as well as to provide relevant mechanistic and adverse outcome pathway (AOP) information in order to cover knowledge gaps and better interpret effect biomarker data. A comprehensive literature search was performed in PubMed to identify all the epidemiologic studies published in the last 10 years addressing the potential relationship between bisphenols exposure and alterations in biological parameters. A total of 5716 references were screened, out of which, 119 full-text articles were analyzed and tabulated in detail. This work provides first an overview of all epigenetics, gene transcription, oxidative stress, reproductive, glucocorticoid and thyroid hormones, metabolic and allergy/immune biomarkers previously studied. Then, promising effect biomarkers related to altered neurodevelopmental and reproductive outcomes including brainderived neurotrophic factor (BDNF), kisspeptin (KiSS), and gene expression of nuclear receptors are prioritized, providing mechanistic insights based on in vitro, animal studies and AOP information. Finally, the potential of omics technologies for biomarker discovery and its implications for risk assessment are discussed. To the best of our knowledge, this is the first effort to comprehensively identify bisphenol-related biomarkers of effect for HBM purposes.European Union Commission H2020-EJP-HBM4EU 733032HBM4EU Initiativ
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