49 research outputs found
Noncomparabilities & Non Standard Logics
- Author
- &
- ??? ?? ? ?? = Max
- ??? ?? ? ?? = Min
- ?� ? ? �??
- A Heyting
- A K Sen
- A N Prior
- A N Whitehead
- Alonzo Church
- Alonzo Church
- Arend Heyting
- Arend Heyting
- C Bass
- C Bass
- C Bass
- C Bass
- C Bass
- C Bass
- C I Lewis
- C I Lewis
- Carmen Dworkin
- Cf
- Crispin Wright
- Crispin Wright
- D Bo?var
- D Bo?var
- D Bo?var
- David Kaplan
- David Kaplan
- David Kaplan
- David Lewis
- David Of Course
- Dummett
- Dummett
- E
- E Beltrametti
- E G
- E G See
- E Ok
- Gottwald
- Graham Priest
- Hans Reichenbach
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- Hilary Putnam
- I Call An "
- I Johanssen
- I Johanssen
- J B R Rosser &
- J Dugundji
- J Dugundji
- J M Mcdowell
- J Mcdowell
- J Pavelka
- J R Lucas
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- Jan ?ukasiewicz
- John Also
- John Broome
- John E Roemer
- John Mcdowell
- John Rawls
- John Rawls
- John Rawls
- John Rawls
- John Rawls
- K Segerberg
- Keith Donnellan
- Keith Donnellan
- Kurt G�del
- Kurt G�del
- L A Zadeh
- L E J Brouwer
- L E J See
- L �qvist
- Leonard Bolc
- M A
- M A E Dummett
- M A E Dummett
- M A E Dummett
- M A E Dummett
- M A E Dummett
- M A E Dummett
- M A E Dummett
- M C Fitting
- M L Dalla Chiara
- Marcus
- Mathias Risse
- Nelson Goodman
- Nelson Goodman
- Nicholas Rescher
- Nicholas Rescher
- P Destouches-F�vrier
- P Frank
- P H�jek
- P Woodruff
- P Woodruff
- Patrick Suppes
- Reason Putnam
- Restatement Rawls
- Restatement Rawls
- Richard Arneson
- Risse
- Robert C. Hockett
- Ronald Dworkin
- Ronald Dworkin
- Ronald Dworkin
- Ronald Dworkin
- S C Kleene
- S C Kleene
- S C Kleene
- S C Kleene
- S Ja?kowski
- S Mccall
- Saul Kripke
- Saul Kripke
- Saul Kripke
- Siegfried Gottwald
- Significantly
- So Argue
- Susan Haack
- T J Smiley
- T J Smiley
- T M Scanlon
- V Nov�k
- Publication venue
- Scholarship@Cornell Law: A Digital Repository
- Publication date
- 01/01/2006
- Field of study
Many normative theories set forth in the welfare economics, distributive justice and cognate literatures posit noncomparabilities or incommensurabilities between magnitudes of various kinds. In some cases these gaps are predicated on metaphysical claims, in others upon epistemic claims, and in still others upon political-moral claims. I show that in all such cases they are best given formal expression in nonstandard logics that reject bivalence, excluded middle, or both. I do so by reference to an illustrative case study: a contradiction known to beset John Rawls\u27s selection and characterization of primary goods as the proper distribuendum in any distributively just society. The contradiction is avoided only by reformulating Rawls\u27s claims in a nonstandard form, which form happens also to cohere quite attractively with Rawls\u27s intuitive argumentation on behalf of his claims
The CC-NB-LRR-Type Rdg2a Resistance Gene Confers Immunity to the Seed-Borne Barley Leaf Stripe Pathogen in the Absence of Hypersensitive Cell Death
- Author
- A Bendahmane
- A Chakrabarti
- A Freialdenhoven
- A Gatti
- A Haegi
- A Haegi
- AF Bent
- AM Hammouda
- Antonio M. Stanca
- AP Rehmany
- BC Meyers
- BC Meyers
- BJ DeYoung
- C Biselli
- C Feuillet
- C Giuliani
- Chiara Biselli
- D Bulgarelli
- D Halterman
- D Leister
- D Tian
- DA Halterman
- DA Jones
- Davide Bulgarelli
- DE Ryerson
- E Mangelsen
- EA Stahl
- F Wei
- F Zhou
- G Delogu
- G Tacconi
- Gabriella Consonni
- Giampiero Valè
- GT Bryan
- J Bergelson
- J Ellis
- J Liu
- JDG Jones
- JL Dangl
- JM McDowell
- K Hyashi
- K Sakata
- K Shirasu
- KJ Mueller
- L Arru
- LC Kramer
- LE Rose
- M Levy
- M Wang
- MB Wang
- Mohammed Bendahmane
- N Pecchioni
- N Yahiaoui
- N Yahiaoui
- Nicholas C. Collins
- NK Bhullar
- PA Anderson
- Paul Schulze-Lefert
- PN Dodds
- QH Shen
- R Görg
- R Hückelhoven
- R Platenkamp
- RA Bhat
- RA Van der Hoorn
- RH Kohler
- RW Michelmore
- S Bieri
- S Seeholzer
- SP Dinesh-Kumar
- VV Solovyev
- W Gassmann
- Y Cao
- Y Yu
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
BACKGROUND: Leaf stripe disease on barley (Hordeum vulgare) is caused by the seed-transmitted hemi-biotrophic fungus Pyrenophora graminea. Race-specific resistance to leaf stripe is controlled by two known Rdg (Resistance to Drechslera graminea) genes: the H. spontaneum-derived Rdg1a and Rdg2a, identified in H. vulgare. The aim of the present work was to isolate the Rdg2a leaf stripe resistance gene, to characterize the Rdg2a locus organization and evolution and to elucidate the histological bases of Rdg2a-based leaf stripe resistance. PRINCIPLE FINDINGS: We describe here the positional cloning and functional characterization of the leaf stripe resistance gene Rdg2a. At the Rdg2a locus, three sequence-related coiled-coil, nucleotide-binding site, and leucine-rich repeat (CC-NB-LRR) encoding genes were identified. Sequence comparisons suggested that paralogs of this resistance locus evolved through recent gene duplication, and were subjected to frequent sequence exchange. Transformation of the leaf stripe susceptible cv. Golden Promise with two Rdg2a-candidates under the control of their native 5′ regulatory sequences identified a member of the CC-NB-LRR gene family that conferred resistance against the Dg2 leaf stripe isolate, against which the Rdg2a-gene is effective. Histological analysis demonstrated that Rdg2a-mediated leaf stripe resistance involves autofluorescing cells and prevents pathogen colonization in the embryos without any detectable hypersensitive cell death response, supporting a cell wall reinforcement-based resistance mechanism. CONCLUSIONS: This work reports about the cloning of a resistance gene effective against a seed borne disease. We observed that Rdg2a was subjected to diversifying selection which is consistent with a model in which the R gene co-evolves with a pathogen effector(s) gene. We propose that inducible responses giving rise to physical and chemical barriers to infection in the cell walls and intercellular spaces of the barley embryo tissues represent mechanisms by which the CC-NB-LRR-encoding Rdg2a gene mediates resistance to leaf stripe in the absence of hypersensitive cell death.Davide Bulgarelli, Chiara Biselli, Nicholas C. Collins, Gabriella Consonni, Antonio M. Stanca, Paul Schulze-Lefert and Giampiero Val
Genetic effects on gene expression across human tissues
- Author
- Abell Nathan S.
- Abell Nathan S.
- Addington Anjene
- Addington Anjene M.
- Aguet François
- Aguet François
- Akey Joshua M.
- Ardlie Kristin G.
- Ardlie Kristin G.
- Balliu Brunilda
- Balliu Brunilda
- Barcus Mary E.
- Barcus Mary E.
- Barker Laura K.
- Barshir Ruth
- Basha Omer
- Bates Daniel
- Battle Alexis
- Billy Li Jin
- Bogu Gireesh K.
- Branton Philip A.
- Branton Philip A.
- Bridge Jason
- Bridge Jason
- Brigham Lori E.
- Brigham Lori E.
- Brown Andrew
- Brown Andrew A.
- Brown Christopher D.
- Bustamante Carlos D.
- Carithers Latarsha J.
- Castel Stephane E.
- Castel Stephane E.
- Chan Joanne
- Chen Lin S.
- Chen Lin S.
- Chiang Colby
- Claussnitzer Melina
- Conrad Donald F.
- Conrad Donald F.
- Cox Nancy J.
- Cox Nancy J.
- Craft Brian
- Cummings Beryl B.
- Cummings Beryl B.
- Damani Farhan N.
- Davis David A.
- Davis David A.
- Davis Joe R.
- Davis Joe R.
- Delaneau Olivier
- Delaneau Olivier
- Demanelis Kathryn
- Dermitzakis Emmanouil T.
- Dermitzakis Emmanouil T.
- Diegel Morgan
- Doherty Jennifer A.
- Engelhardt Barbara E.
- Eskin Eleazar
- Eskin Eleazar
- Feinberg Andrew P.
- Fernando Marian S.
- Ferreira Pedro G.
- Flicek Paul
- Foster Barbara A.
- Foster Barbara A.
- Frésard Laure
- Frésard Laure
- Gamazon Eric R.
- Gamazon Eric R.
- Garrido-Martín Diego
- Garrido-Martín Diego
- Gelfand Ellen T.
- Gelfand Ellen T.
- Getz Gad
- Getz Gad
- Gewirtz Ariel D.H.
- Gewirtz Ariel D.H.
- Gillard Bryan M.
- Gillard Bryan M.
- Gliner Genna
- Gliner Genna
- Gloudemans Michael J.
- Gloudemans Michael J.
- Goldman Mary
- Gould Sarah E.
- Guan Ping
- Guan Ping
- Guigo Roderic
- Guigó Roderic
- Hadley Kane
- Hadley Kane
- Haeussler Maximilian
- Hall Ira M.
- Halow Jessica
- Han Buhm
- Han Buhm
- Handsaker Robert E.
- Hansen Kasper D.
- Hariharan Pushpa
- Hasz Richard
- Hasz Richard
- Haugen Eric
- He Amy Z.
- He Yuan
- He Yuan
- Hickey Peter F.
- Hormozdiari Farhad
- Hormozdiari Farhad
- Hou Lei
- Howald Cedric
- Huang Katherine H.
- Huang Katherine H.
- Hunter Marcus
- Hunter Marcus
- Hunter Steven
- Jasmine Farzana
- Jewell Scott D.
- Jewell Scott D.
- Jian Ruiqi
- Jiang Lihua
- Jo Brian
- Jo Brian
- Johns Christopher
- Johns Christopher
- Johnson Audra
- Johnson Mark
- Johnson Mark
- Juettemann Thomas
- Kang Eun Yong
- Karasik Ellen
- Karasik Ellen
- Karczewski Konrad J.
- Kashin Seva
- Kaul Rajinder
- Kellis Manolis
- Kellis Manolis
- Kent W. James
- Kibriya Muhammad G.
- Kim Yungil
- Kim-Hellmuth Sarah
- Koester Susan
- Koester Susan E.
- Kopen Gene
- Kopen Gene
- Kumar Rachna
- Kumar Rachna
- Kyung Im Hae
- Lappalainen Tuuli
- Lappalainen Tuuli
- Lee Christopher M.
- Lee Kristen
- Leinweber William F.
- Leinweber William F.
- Lek Monkol
- Lek Monkol
- Li Gen
- Li Gen
- Li Qin
- Li Xiao
- Li Xiao
- Li Xiao
- Li Xin
- Li Xin
- Lin Jessica
- Lin Shin
- Linder Sandra
- Linke Caroline
- Little A. Roger
- Little A. Roger
- Liu Boxiang
- Liu Boxiang
- Liu Yaping
- Lockart Nicole C.
- Lockhart Nicole C.
- Lonsdale John T.
- Lonsdale John T.
- MacArthur Daniel G.
- MacArthur Daniel G.
- Mangul Serghei
- Martin Casey
- Mash Deborah C.
- Mash Deborah C.
- Matose Takunda
- Maurano Matthew T.
- McCarthy Mark I.
- McCarthy Mark I.
- McDonald Alisa
- McDonald Alisa
- McDowell Ian C.
- McDowell Ian C.
- McLean Jeffrey A.
- Mestichelli Bernadette
- Mestichelli Bernadette
- Miklos Mark
- Miklos Mark
- Mohammadi Pejman
- Mohammadi Pejman
- Molinie Benoit
- Monlong Jean
- Montgomery Stephen B.
- Montgomery Stephen B.
- Montroy Robert G.
- Montroy Robert G.
- Moore Helen M.
- Moore Helen M.
- Mosavel Maghboeba
- Moser Michael T.
- Moser Michael T.
- Muñoz-Aguirre Manuel
- Myer Kevin
- Myer Kevin
- Ndungu Anne W.
- Nedzel Jared L.
- Nedzel Jared L.
- Nelson Jemma
- Neri Fidencio J.
- Nguyen Duyen T.
- Nguyen Duyen Y.
- Nicolae Dan L.
- Nierras Concepcion R.
- Nobel Andrew B.
- Nobel Andrew B.
- Noble Michael S.
- Noble Michael S.
- Oliva Meritxell
- Oliva Meritxell
- Ongen Halit
- Ongen Halit
- Palowitch John J.
- Palowitch John J.
- Panousis Nikolaos
- Papasaikas Panagiotis
- Park Yongjin
- Park YoSon
- Park YoSon
- Parsana Princy
- Parsana Princy
- Paten Benedict
- Payne Anthony J.
- Peterson Christine B.
- Peterson Christine B.
- Pierce Brandon L.
- Qi Liqun
- Quan Jie
- Quon Gerald
- Rao Abhi
- Rao Abhi
- Reverter Ferran
- Rinaldi Nicola J.
- Ripke Stephan
- Rizzardi Lindsay F.
- Robinson Karna L.
- Roche Nancy V.
- Roe Brian
- Roe Bryan
- Rohrer Daniel C.
- Rohrer Daniel C.
- Rosenbloom Kate R.
- Ruffier Magali
- Sabatti Chiara
- Sabatti Chiara
- Saha Ashis
- Saha Ashis
- Salvatore Michael
- Salvatore Michael
- Sammeth Michael
- Sandstrom Richard
- Scott Alexandra J.
- Segrè Ayellet V.
- Segrè Ayellet V.
- Shabalin Andrey A.
- Shabalin Andrey A.
- Shad Saboor
- Shad Saboor
- Sheppard Dan
- Shimko Tyler C.
- Siminoff Laura A.
- Singh Shilpi
- Skol Andrew
- Smith Anna M.
- Smith Kevin S.
- Snyder Michael P.
- Sobin Leslie
- Sobin Leslie
- Sodaei Reza
- Stamatoyannopoulos John
- Stephens Matthew
- Stranger Barbara E.
- Stranger Barbara E.
- Stranger Barbara E.
- Strober Benjamin J.
- Strober Benjamin J.
- Struewing Jeffery P.
- Struewing Jeffery P.
- Sul Jae Hoon
- Sul Jae Hoon
- Sullivan Timothy J.
- Tabor David E.
- Tang Hua
- Taylor Kieron
- Teran Nicole A.
- Thomas Jeffrey A.
- Thomas Jeffrey A.
- Tomaszewski Maria M.
- Traino Heather M.
- Trevanion Stephen J.
- Trowbridge Casandra A.
- Tsang Emily K.
- Tsang Emily K.
- Tsang Emily K.
- Tukiainen Taru
- Tukiainen Taru
- Um Ki Sung
- Undale Anita H.
- Urbut Sarah
- Valentino Kimberly M.
- Valley Dana
- Valley Dana R.
- van de Bunt Martijn
- Van Wittenberghe Nicholas
- Vatanian Negin
- Vaught Jimmie B.
- Vivian John
- Volpi Simona
- Volpi Simona
- Walters Gary
- Walters Gary
- Wang Gao
- Wang Li
- Wang Meng
- Washington Michael
- Washington Michael
- Wen Xiaoquan
- Wen Xiaoquan
- Wheeler Joseph
- Wheeler Joseph
- Wright Fred A.
- Wright Fred A.
- Wu Fan
- Xi Hualin S.
- Yeger-Lotem Esti
- Yong Kang Eun
- Zappala Zachary
- Zappala Zachary
- Zaugg Judith B.
- Zerbino Daniel R.
- Zhang Hailei
- Zhang Rui
- Zhou Yi-Hui
- Zhou Yi-Hui
- Zhu Jingchun
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels across individuals and diverse tissues of the human body, many of which are not easily accessible. Here we describe genetic effects on gene expression levels across 44 human tissues. We find that local genetic variation affects gene expression levels for the majority of genes, and we further identify inter-chromosomal genetic effects for 93 genes and 112 loci. On the basis of the identified genetic effects, we characterize patterns of tissue specificity, compare local and distal effects, and evaluate the functional properties of the genetic effects. We also demonstrate that multi-tissue, multi-individual data can be used to identify genes and pathways affected by human disease-associated variation, enabling a mechanistic interpretation of gene regulation and the genetic basis of diseas
Calibration of the CMS hadron calorimeters using proton-proton collision data at root s=13 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adamov George
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Agyel D.
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anagul S.
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Assran Yasser
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Baldenegro Barrera Cristian
- Ball Austin
- Ball Fionn
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Barth Christian
- Bartosik Nazar
- Bartók Márton
- Baselga Marta
- Bastos Diogo
- Bat Ayse
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baur Sebastian
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beernaert Kelly
- Beghin Diego
- Behera Prafulla Kumar
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Benvenuti Alberto
- Beretvas Andrew
- Bergauer Thomas
- Berger Pirmin
- Berger Thomas
- Beri Suman Bala
- Bermúdez Martínez Armando
- Bernardes Cesar Augusto
- Bernet Colin
- Berry Douglas
- Berryhill Jeffrey
- Bertacchi Valerio
- Bertsche David
- Besancon Marc
- Beschi Andrea
- Betts Russell Richard
- Bhal Eshwen
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhardwaj Rishika
- Bharti Monika
- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhattacharya Soham
- Bhawandeep Bhawandeep
- Bheesette Srinidhi
- Bhopatkar Vallary
- Bhowmik Debabrata
- Bhowmik Sandeep
- Bhyun Ji Hwan
- Bi Ran
- Bialkowska Helena
- Bianchini Lorenzo
- Bianco Michele
- Bianco Stefano
- Biasini Maurizio
- Biino Cristina
- Bilei Gian Mario
- Bilican F.
- Bilin Bugra
- Bilki Burak
- Bin Anuar Afiq Aizuddin
- Bisello Dario
- Bitioukov Sergei
- Blekman Freya
- Blinov Vladimir
- Blobel Volker
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bozena
- Boletti Alessio
- Bologna Simone
- Bols Emil Sørensen
- Bonacorsi Daniele
- Bonchev Miroslav
- Bondu Olivier
- Boos Edouard
- Boran Fatma
- Borchsh Vladislav
- Boren Samuel
- Borg Johan
- Borgonovi Lisa
- Bornheim Adolf
- Borras Kerstin
- Bortignon Pierluigi
- Bose Tulika
- Bossini Edoardo
- Botta Cristina
- Botta Valeria
- Boudoul Gaelle
- Bouhali Othmane
- Bourgatte Guillaume
- Bourilkov Dimitri
- Bowen James
- Bozzo Marco
- Bragagnolo Alberto
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brainerd Christopher
- Brandstetter Johannes
- Brandt Stephanie
- Branson James G
- Bravo Cameron
- Breedon Richard
- Breeze Shane
- Brew Christopher
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M
- Brun Hugues
- Bruno Giacomo
- Brzhechko Danyyl
- Bucci Rachael
- Buccilli Andrew
- Buchanan James
- Buchmuller Oliver
- Bueghly James
- Bundock Aaron
- Bunin Pavel
- Bunkowski Karol
- Buontempo Salvatore
- Burkett Kevin
- Burkle Bjorn
- Burns Douglas
- Burt Kira
- Busson Philippe
- Busza Wit
- Butler Joel Nathan
- Butler Philip H
- Butz Erik
- Bylinkin Alexander
- Bylsma Ben
- Byszuk Adrian
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol Cécile
- Cakir Altan
- Calabria Cesare
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Call Kenneth
- Calligaris Luigi
- Camen Camille
- Caminada Lea
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Canepa Anadi
- Cankocak Kerem
- Capiluppi Paolo
- Cappati Alessandra
- Caputo Claudio
- Caratelli Alessandro
- Cardini Andrea
- Carlin Roberto
- Carlsmith Duncan
- Carnes Andrew
- Carrera Jarrin Edgar
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Casarsa Massimo
- Caspart René
- Cassese Antonio
- Castaldi Rino
- Castaneda Hernandez Alfredo
- Castilla-Valdez Heriberto
- Castro Andrea
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceccarelli Rudy
- Ceci Sasa
- Celik Ali
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Cerri Olmo
- Chabert Eric Christian
- Chadeeva Marina
- Chang Paoti
- Chang Philip
- Chanon Nicolas
- Chao Yuan
- Chaparro Sierra Luisa Fernanda
- Chapon Emilien
- Charlot Claude
- Chatterjee Kalyanmoy
- Chatterjee Rajdeep Mohan
- Chatterjee Suman
- Chauhan Shubhanshu
- Chauhan Sushil
- Chaves Jorge
- Chawla Ridhi
- Chazin Quero Barbara
- Checchia Paolo
- Chekhovsky Vladimir
- Chen Geng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Xuan
- Chen Yuan
- Chenarani Shirin
- Cheng Tongguang
- Cheng Yangyang
- Cherepanov Vladimir
- Chernyavskaya Nadezda
- Chertok Maxwell
- Cheung Harry
- Chhibra Simranjit Singh
- Chiarito Brandon
- Chierici Roberto
- Chinellato Jose
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- Yusli Mohd Nizam
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- Zaganidis Nicolas
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Anna
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zlebcik Radek
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Methods are presented for calibrating the hadron calorimeter system of theCMSetector at the LHC. The hadron calorimeters of the CMS experiment are sampling calorimeters of brass and scintillator, and are in the form of one central detector and two endcaps. These calorimeters cover pseudorapidities vertical bar eta vertical bar ee data. The energy scale of the outer calorimeters has been determined with test beam data and is confirmed through data with high transverse momentum jets. In this paper, we present the details of the calibration methods and accuracy.Peer reviewe
Genetic effects on gene expression across human tissues
- Author
- Abell Nathan S.
- Addington Anjene M.
- Addington Anjene M.
- Aguet François
- Akey Joshua M.
- Ardlie Kristin G.
- Balliu Brunilda
- Barcus Mary E.
- Barker Laura K.
- Barshir Ruth
- Basha Omer
- Bates Daniel
- Battle Alexis
- Bogu Gireesh K.
- Branton Philip A.
- Bridge Jason
- Brigham Lori E.
- Brown Andrew A.
- Brown Christopher D.
- Bustamante Carlos D.
- Carithers Latarsha J.
- Castel Stephane E.
- Chan Joanne
- Chen Lin S.
- Chiang Colby
- Claussnitzer Melina
- Conrad Donald F.
- Cox Nancy J.
- Craft Brian
- Cummings Beryl B.
- Damani Farhan N.
- Davis David A.
- Davis Joe R.
- Delaneau Olivier
- Demanelis Kathryn
- Dermitzakis Emmanouil T.
- Diegel Morgan
- Doherty Jennifer A.
- Engelhardt Barbara E.
- Eskin Eleazar
- Feinberg Andrew P.
- Fernando Marian S.
- Ferreira Pedro G.
- Flicek Paul
- Foster Barbara A.
- Frésard Laure
- Gamazon Eric R.
- Garrido-Martín Diego
- Gelfand Ellen T.
- Getz Gad
- Gewirtz Ariel D.H.
- Gillard Bryan M.
- Gliner Genna
- Gloudemans Michael J.
- Goldman Mary
- Gould Sarah E.
- Guan Ping
- Guigó Roderic
- Hadley Kane
- Haeussler Maximilian
- Hall Ira M.
- Halow Jessica
- Han Buhm
- Handsaker Robert E.
- Hansen Kasper D.
- Hariharan Pushpa
- Hasz Richard
- Haugen Eric
- He Amy Z.
- He Yuan
- Hickey Peter F.
- Hormozdiari Farhad
- Hou Lei
- Howald Cedric
- Huang Katherine H.
- Hunter Marcus
- Hunter Steven
- Im Hae Kyung
- Jasmine Farzana
- Jewell Scott D.
- Jian Ruiqi
- Jiang Lihua
- Jo Brian
- Johns Christopher
- Johnson Audra
- Johnson Mark
- Juettemann Thomas
- Kang Eun Yong
- Karasik Ellen
- Karczewski Konrad J.
- Kashin Seva
- Kaul Rajinder
- Kellis Manolis
- Kent W. James
- Kibriya Muhammad G.
- Kim Yungil
- Kim-Hellmuth Sarah
- Koester Susan
- Koester Susan E.
- Kopen Gene
- Kumar Rachna
- Lappalainen Tuuli
- Lee Christopher M.
- Lee Kristen
- Leinweber William F.
- Lek Monkol
- Li Gen
- Li Jin Billy
- Li Qin
- Li Xiao
- Li Xin
- Lin Jessica
- Lin Shin
- Linder Sandra
- Linke Caroline
- Little A. Roger
- Liu Boxiang
- Liu Yaping
- Lockart Nicole C.
- Lockhart Nicole C.
- Lonsdale John T.
- MacArthur Daniel G.
- Mangul Serghei
- Martin Casey
- Mash Deborah C.
- Matose Takunda
- Maurano Matthew T.
- McCarthy Mark I.
- McDonald Alisa
- McDowell Ian C.
- McLean Jeffrey A.
- Mestichelli Bernadette
- Miklos Mark
- Mohammadi Pejman
- Molinie Benoit
- Monlong Jean
- Montgomery Stephen B.
- Montroy Robert G.
- Moore Helen M.
- Mosavel Maghboeba
- Moser Michael T.
- Muñoz-Aguirre Manuel
- Myer Kevin
- Ndungu Anne W.
- Nedzel Jared L.
- Nelson Jemma
- Neri Fidencio J.
- Nguyen Duyen T.
- Nguyen Duyen Y.
- Nicolae Dan L.
- Nierras Concepcion R.
- Nobel Andrew B.
- Noble Michael S.
- Oliva Meritxell
- Ongen Halit
- Palowitch John J.
- Panousis Nikolaos
- Papasaikas Panagiotis
- Park Yongjin
- Park YoSon
- Parsana Princy
- Paten Benedict
- Payne Anthony J.
- Peterson Christine B.
- Pierce Brandon L.
- Qi Liqun
- Quan Jie
- Quon Gerald
- Rao Abhi
- Reverter Ferran
- Rinaldi Nicola J.
- Ripke Stephan
- Rizzardi Lindsay F.
- Robinson Karna L.
- Roche Nancy V.
- Roe Bryan
- Rohrer Daniel C.
- Rosenbloom Kate R.
- Ruffier Magali
- Sabatti Chiara
- Saha Ashis
- Salvatore Michael
- Sammeth Michael
- Sandstrom Richard
- Scott Alexandra J.
- Segrè Ayellet V.
- Shabalin Andrey A.
- Shad Saboor
- Sheppard Dan
- Shimko Tyler C.
- Siminoff Laura A.
- Singh Shilpi
- Skol Andrew
- Smith Anna M.
- Smith Kevin S.
- Snyder Michael P.
- Sobin Leslie
- Sodaei Reza
- Stamatoyannopoulos John
- Stephens Matthew
- Stranger Barbara E.
- Strober Benjamin J.
- Struewing Jeffery P.
- Sul Jae Hoon
- Sullivan Timothy J.
- Tabor David E.
- Tang Hua
- Taylor Kieron
- Teran Nicole A.
- Thomas Jeffrey A.
- Tomaszewski Maria M.
- Traino Heather M.
- Trevanion Stephen J.
- Trowbridge Casandra A.
- Tsang Emily K.
- Tukiainen Taru
- Um Ki Sung
- Undale Anita H.
- Urbut Sarah
- Valentino Kimberly M.
- Valley Dana
- Van De Bunt Martijn
- Van Wittenberghe Nicholas
- Vatanian Negin
- Vaught Jimmie B.
- Vivian John
- Volpi Simona
- Walters Gary
- Wang Gao
- Wang Li
- Wang Meng
- Washington Michael
- Wen Xiaoquan
- Wheeler Joseph
- Wright Fred A.
- Wu Fan
- Xi Hualin S.
- Yeger-Lotem Esti
- Zappala Zachary
- Zaugg Judith B.
- Zerbino Daniel R.
- Zhang Hailei
- Zhang Rui
- Zhou Yi-Hui
- Zhu Jingchun
- Publication venue
- Publication date
- 01/01/2017
- Field of study
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels across individuals and diverse tissues of the human body, many of which are not easily accessible. Here we describe genetic effects on gene expression levels across 44 human tissues. We find that local genetic variation affects gene expression levels for the majority of genes, and we further identify inter-chromosomal genetic effects for 93 genes and 112 loci. On the basis of the identified genetic effects, we characterize patterns of tissue specificity, compare local and distal effects, and evaluate the functional properties of the genetic effects. We also demonstrate that multi-tissue, multi-individual data can be used to identify genes and pathways affected by human disease-associated variation, enabling a mechanistic interpretation of gene regulation and the genetic basis of disease
Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Aaron Joffe
- Aaron Mark Hernandez
- Aaron Mark Hernandez
- Abby Lewis
- Abdelhamid Hachimi
- Abdualhamid I Alshrif
- Abel Viveiros
- Abhijit Duggal
- Abidin Oner Balbay
- Achilleas Chovas
- Ade Susanti
- Adi Hadzibegovic
- Adonis Dungca
- Adrian Belii
- Adrian Belii
- Adriana Onelli
- Afolabi Owojuyigbe
- Agnieszka Kubisz-Pudelko
- Agnès Blanc
- Ahmed Ali Aboufray
- Ahmed Elhadi
- Ahmed Ramadan Triki
- Ahmed Subhy Alsheikhly
- Ahmed Zaki
- Ahmet Eroglu
- Aidan O'Shea
- Aikaterini Dimoula
- Aikaterini Efthimiou
- Aikaterini Flevari
- Ailesh Corcoran
- AiPing Bi
- Aiua Ren
- Aizhi Zhang
- Ajitha Rajendran
- Akemi Hirao
- Akira Ohuchi
- Aktham Yaghi
- Ala Khaled
- Alan Sustic
- Alan Sustic
- Alba Riera
- Alban Greca
- Alberto de Jesús Ortiz
- Alberto Peratoner
- Alejandra Aucapina
- Alejandra Azahara Marguello Fernandez
- Alejandro Ibarra
- Aleksandar Šuput
- Aleksandra Gutysz-Wojnicka
- Alessandra Negro
- Alessandro Di Risio
- Alessandro Galazzi
- Alexander Dullenkopf
- Alexander Kiselev
- Alexander Tsarev
- Alexandra Pivkina
- Alexandra Vasquez
- Alexis Tabah
- Ali Kağnıcı
- Alida Moise
- Aline Ramalho
- Alinoy Lavy
- Alisha van Axel
- Alma Cani
- Alvaro Ortega Guerrero
- Amalia Corso
- Amber Markham
- Amelia Ferreira
- Amer Assiri
- Amilcar Garcia
- Amilcar Garcia
- Amit Gupta
- Amit Gupta
- Amy Collins
- Amy Thompson
- Amy Walsh
- Amylkar Garay Reyes
- Amylkar José Garay Reyes
- Ana Alabart Llinas
- Ana Alícia Velarde Pineda
- Ana Bantar
- Ana Belén Curto Polo
- Ana Belén Sánchez de la Ventana
- Ana Diaz
- Ana Diaz
- Ana Isabel Clement
- Ana Laura Gonzalez
- Ana Lucia Vitti Ronchini
- Ana Margarida Feranandes
- Ana María De Pablo
- Ana Pascual-Bielsa
- Ana Tavares
- Ana Vochin
- Ana Wensell Fernández
- Anastasia Spyropoulou
- Anastasio Espejo Cano
- Andeas Stübner
- Andrea Bruni
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Cortegiani
- Andrea Giampaoletti
- Andrea Martonova
- Andrea Martonova
- Andrea McDonnell
- Andrea McLucas
- Andrej Markota
- Andrijan Kartalov
- Andréa Maria Laizner
- Andréa Maria Laizner
- Andréa Maria Laizner
- Ane Stenset
- Angela Trposak
- Angelica Olivetto de Almeida
- Anisette Hoegenhaven
- Anita Alias
- Anita Jans
- Anita Vuković
- Anita-Chrysolyte Kusi-Appiah
- Anja Diers
- Anja Hansen
- Ann-Sofie Malvemyr
- Anna Alexandrou
- Anna Diaz
- Anna Efthymiou
- Anna Kyriakoudi
- Anna Leonova
- Anna Vita Bruno
- Anne Fishman
- Anne Langvad
- Anne Marie Kodal
- Anne Sofie Bomholt Pedersen
- Anne Williams
- Anne-Sophie Debue
- Annette Carey
- Annette Toellefsen
- Anthony Adenekan
- Anthony Radavidson
- Antigoni Karathanou
- Anton Turčan
- Antonella Cotoia
- Antonella Mo
- Antoni Margarit Ribas
- Antonia Liarmakopoulou
- Antonija Petosic
- Antonino Rizzo
- Antonio Abdala
- Antonio Barone
- Antonio Landaverde
- Antonio Manzo
- Antonio Margarit Ribas
- Antony Eneas
- Apostolos Bakas
- Arena Raimondo
- Arif Moghal
- Aristeidis Vakalos
- Arlette Van Den Elst
- Armanda Bozena
- Armando Schmukler
- Armorel Salberg
- Artemis Patsalos
- Arturo Briva
- Arvind Baronia
- Asbjorn Blondal
- Ascanio Tridente
- Ashish K Khanna
- Ashish K Khanna
- Ashish Khanna
- Ashley Szabo Eltorai
- Ashok Sundai Raj
- Ashwaq Ali
- Asmah Zainudin
- Asu Ozgultekin
- Ata Mahmoodpoor
- Athena Lavrentieva
- Attilio Quaini
- Audrey Fioretti
- Audrey Massard
- Auke Reidinga
- Auli Palmu
- Avşar Zerman
- Aya Alabuzidi
- Ayako Noguchi
- Ayça Gümüş
- Azmin Huda Abdul Rahim
- Babangida John Sankey
- Badiola Hilario
- Banu Taşdemir
- Baoke Zhang
- Barbara Garcia
- Barbro Meland
- Bart Ramaker
- Basri Mat Nor
- Battsetseg Baasanjav
- Başar Erdivanli
- Başar Erdivanli
- Beatrice Pastore
- Begoña Zalba-Etayo
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- Belinda Guadi-Gosh
- Ben Attwood
- Benjamin Bongiorno
- Benjamin Gerretsen
- Benoît Chinardet
- Berenice Navarro
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- Bernardo Panka
- Bernd Oliver Rose
- Bert Loef
- Betty Star Kampayana
- Beverley Thomas
- Beysim Özcan
- Beysim Özcan
- Bhagyesh Shah
- Biljana Kuzmanovska
- Bindu Thankamma
- Bing Song
- Binny Tuinstra
- Birgitte Fosser Johansen
- Birthe Husted
- Biyan Li
- Bjoern Monsen
- Bjorn Bratsberg
- Bodin Khwannimit
- Bogdan Raitsiou
- Bojan Jovanovic
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- Bram Kilapong
- Bram Kilapong
- Branislava Stefanovic
- Brian Marsh
- Brigitte Tejeda-Huezo
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- Elsa Afonso
- Emanuel Valgolio
- Emiliano Dean
- Emilio Maseda
- Emma Aves
- Emma Moreno Barreiro
- Emma Parkin
- Enas Soula
- Eneli Anvelt
- Enora Atchade
- Epaminontas Farmakis
- Erik Roman-Pognuz
- Erika Backlund Jansson
- Eryun Tian
- Esben Straede
- Esteban Milioto
- Estefania Orozco
- Estefanía Prol-Silva
- Estevão Lafuente
- Etienne De Montmollin
- Eugenio Garofalo
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- Eugeniya Larina
- Eulália Luis
- Eumorfia Kondili
- Eunice Tole
- Eva Joelsson-Alm
- Eva Joelsson-Alm
- Eva Åkerman
- Eva Åkerman
- Evangelia Michailidou
- Evdokia Sourla
- Evellyn Oliveira
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- Ewa Wahlbom
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- Jarone Lee
- Jasdeep Dhaliwal
- Jasmina Smajic
- Jasmina Smajic
- Jason Cupitt
- Jasper Haringman
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- Javier Bogarin
- Javier Lorenzo
- Javier Ripolles-Melchor
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- Javiera Soledad
- Jayne Craig
- Je Hyeong Kim
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- Jean-Christophe Farkas
- Jean-Francois Timsit
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- Jianhong Wan
- Jie Gao
- JiFen Zhu
- Jin Liu
- Jin Won Huh
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- JinHui Song
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- Jisoo Park
- Jiye Guo
- Jiyin Cheng
- Jo Jones
- Joanne White
- Joao Azoia
- Joaquin Aguirre
- Joerg C Schefold
- Joerg C Schefold
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- Jonghyun Baek
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- José Manuel Garcia Pena
- José Peral Gutierrez de Ceballos
- José Rojas-Suarez
- Jowena Ibao
- João Cabral
- João Vieira
- Juan Carlos Rivas
- Juan Cata
- Juan Ignacio Torres Gonzalez
- Juan P Romero-Gonzalez
- Juan Sebastian Hernandez
- Juan Wu
- Judy Enamorado
- Judy Enamorado Enamorado
- Julia Kovaleva
- Julie Benbenishty
- Julie Benbenishty
- Julie Benbenishty
- Julie Camsooksai
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- Jun Kataoka
- Jundi Zhang
- Jung-Min Bae
- Junghyun Kim
- Junping Hao
- Justin Woods
- Justine Somerville
- Kadri Tamme
- Karely Duran
- Karen Baxter
- Karen Boulton
- Karen Burns
- Karen Cranmer
- Karen Habgood
- Karen Williams
- Karianne Dale Jensen
- Karin Kaasby
- Karin Rehnholt Pedersen
- Kathleen Ann Smiley
- Kathrin Bösl
- Keevan Singh
- Kefang Wang
- Kellie Sosnowski
- Kelly Fletcher
- Kelly Fletcher
- Kelly Matthews
- Kelly Matthews
- Kenji Takahashi
- Kerrie Martin
- Kerry Wright
- Kevin Hatton
- Kewei Liu
- Khaled Al Qawasmeh
- Khalid Abidi
- Khalid Abidi
- Khalid Mahmood Khan Nafees
- Khalid Mahmood Khan Nafees
- Kishore Mangal
- Kit Weng Foong
- Koen De Decker
- Koji Fujimoto
- Konlawij Trongtrakul
- Konlawij Trongtrakul
- Konlawij Trongtratul
- Konstantina Nestora
- Konstantinos Mandis
- Konstantinos Pagioulas
- Konstantinos Psarulis
- Kounougeri Katerina
- Kristina Mariana Matei Stalika
- Kristina Reinertsen Monstad
- Kristy Masters
- Kumi Maruyama
- Kunal Karamchandani
- Kyeongman Jeon
- Kyriaki Tsikritsaki
- Kyung Chan Kim
- Laetitia Boyer
- Laila Kamaliah Kamalul Bahrin
- Lakshay Bhakhtiani
- Lamia Besbes
- Lamia Ouanes Besbes
- Lamprini Avramopoulou
- Laura Bormans
- Laura Cespedes
- Laura Claramunt Domenech
- Laura Martinez Reyes
- Laura Maulicino
- Laura Pedro
- Laura Van Gulik
- Lea Albrecht
- Leah Flores
- Leanne Parsons
- Lee Yeon-Joo
- Lei Chen
- Lei Lei
- Lei Tan
- Lei Yang
- Leif Saager
- Leif Saager
- Leif Saager
- Lena Napolitano
- Lenneke Haas
- Lesia Zgrzheblovska
- Lesia Zgrzheblovska
- Leticia Serpa
- Lettie Van Den Berg
- Li Chuntang Li
- Li Gao
- Li Hong
- Li Ping Hu
- Li Xixi
- Li Yin
- Libing Zhang
- Lidia Glinka
- Lidia Traina
- Liesbet Demarré
- Lihong Liu
- Liivi Maddison
- Liivi Maddison
- Lijuan Zhao
- Lili Hu
- Lili Tuo
- Limei Fan
- Limei Miao
- Lin InSu
- Lina Xiao
- Lina Xu
- Lina Zhao
- Ling Li
- Ling Liu
- Ling Zhang
- LingLing Wang
- Linlin Luan
- LiPing Huang
- Lisa Dunne
- Lisa Høgvall
- Liu Hong
- Liudmila Fadeeva
- Liudmila Grishina
- Liuyan Ge
- Liz Wilby
- Llesley Chadwick
- Lomangisi Dlamini-Sserumaga
- Lorena Del Rio Cabajo
- Lorna Merritt-Charles
- Lorna Merritt-Charles
- Lorraine Thompson
- Losune Cano Sanchez
- Lotta Johansson
- Lotti Orvelius
- Louise Barr
- Louise Bruhn
- Louise Maltby
- Louise Rose
- Louise Rose
- Louise Rose
- Lu Liu
- Luc-Marie Jacquet
- Lucia Hernandez-Ponce
- Lucia Mirabella
- Lucia Stivanello
- Luciano Bonaccorso
- Lucie Mouton
- Luis Alejandro Sanchez-Hurtado
- Luis Camputaro
- Luis Gorordo-Delsol
- Luis Mario Tamayo
- Luis Mendes
- Luis Pedro Ambriz Nava
- Luis Sánchez-Hurtado
- Luz Coronado Sanz
- Luz Marina Silva Gama
- Ly Yuemen
- Lydia Gallego Aguirre
- Lynette Morrison
- Lynette Newby
- Lynne Williams
- Léa Soulisse
- M Del Rosario Villar Redondo
- M Llaurado-Serra
- Ma Hong
- Maarit Ahtiala
- Madeleine Powell
- Madhu Balasubramanian
- Madiha Hashmi
- Madiha Hashmi Ffarcsi
- Mae Templeton
- Magnus Teig
- Maie Ebaid
- Maie Salem Ebaid
- Maija Anniina Valta
- Maija Valta
- Maja Sostaric
- Maja Stanojević
- Majd Tabib
- Maksim Tribulev
- Mala Elgammudi
- Malcolm C Correia
- Malgorzata Mikaszewska-Sokolewicz
- Malgorzata Mikaszewska-Sokolewicz
- Man Liu
- Man Ye
- Mandy Hughes
- Mandy Tallot
- Manish Gupta
- Manoj Kamal
- Manuel Lois
- Maram Milud Said Al-Alawi
- Marat Magomedov
- Marc Bota
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- Marc Gallion
- Marcela Mastantuono
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- Marcos Hernandez-Romero
- Margaret Lynn Jong
- Margarida Ferreira Figueiredo
- Margarita Campos-Perez
- Margherita Boschetto
- Margijske Vanroest
- Maria Alejandra Fernandez
- Maria Angeles Hurtado Sanchez
- Maria Aranzazu Isasi
- Maria Ayala
- Maria Carmen Gorgolas
- Maria Cossu
- Maria Cristina Iglesias Fernandez
- Maria Del Mar Diaz Salcedo
- Maria Donvito
- Maria Fernanda García
- Maria Foka
- Maria Galiana
- Maria Gracia San Antonio
- Maria Idalia Sepulveda
- Maria Liz Moreira
- Maria Luisa Blasco
- Maria Mylordou
- Maria Pilar Sogues Blanco
- Maria Rosa Taibi
- Maria Schofield Legorburo
- Maria Stafylaraki
- Maria Varela
- Maria-Elena Ochoa
- Mariangeles Gabriela Nocheretti
- Marianne Maus
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- Marija Rajković
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- Mario Del Moral Armengol
- Mario Ramirez
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- Marios Georgiou
- Marisa Onrust
- Marit Hildegunn Andersen
- Marit Nyhus
- Mark Fielding
- Mark Fielding
- Mark Pulletz
- Mark Van Den Brink
- Mark van der Kuil
- Marta Borkowska
- Marta Tubacka
- Martin Christ
- Martin Kütimets
- Martin Lang
- Martin Rinket
- Martin Roller
- Martin Sills
- Martin Spångfors
- Martina Lausch
- Mary Coman
- María Luisa Bravo Arcas
- María Ocotlan Gonzalez Herrera
- Masakatsu Nananmori
- Masako Shimizu
- Matias Guereschi
- Matias Jesús Flamm Zamorano
- Matjaž Groznik
- Matteo Bossolasco
- Matthew Jackson
- Matthia Mergeay
- Matty Koopmans
- Matías Baini
- Maxim Petrushin
- Mayang Indah Lestari
- Mayra Martinez-Gonzalez
- Mayumi Tsujimoto
- Mazal Azencot
- Meena Manandhar
- Megan McQuirter
- Mei Jiang
- Mei Ye
- Mei Yu Hsu
- Meili Chen
- Melike Cengiz
- Mendsaikhan Naranpurev
- Mendsaikhan Naranpurev
- Meneses Dayan
- Mengmeng Lv
- Meraj Ahmad
- Mercedes Del Cotillo
- Mercè Girona
- Meritxell Tapia Fores
- Merja Merilainen
- Meropi Mpouzika
- Mervyn Mer
- Metaxia Papanikolaou
- Mette From
- Mette Lund
- Mhamed Sami Mebazaa
- Mia Hylen
- Mia Thorning Miller
- Miao Li
- Miao Liu
- Michael Isanan
- Michael Piradov
- Michal Borys
- Michel El Feghaly
- Michele Clark
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- Michelle Kotze
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- Mieke Deschepper
- Miguel Angel Gimenez Lajara
- Miguel Ángel Sosa
- Mihai Popescu
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- Mihails Dolgusevs
- Milena Dobric
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- Milica Lukic
- Min Ding
- Min Song
- Min Xiao
- Min Yu
- Mina Elkhayari
- Mina Mathaios
- Minna Peltomaa
- Miquel Sanz
- Mireia Llaurado-Serra
- Mireia Llaurado-Serra
- Mirjam Evers
- Mirjana Shosholcheva
- Mirjana Shosolcheva
- Miroslaw Czuczwar
- Misa Fister
- Missael Vladimir Espinoza Villafuerte
- Mohamed Abdurazzag Ali Ghula
- Mohamed Benlamin
- Mohan Gurjar
- Mohan Gurjar
- Mohd Basri Mat Nor
- Mohd Nazri Ali
- Mohd Zulfakar Mazlan
- Mohd Zulfakar Mazlan
- Mona Ringdal
- Monica Adriana Scutariu
- Monica Garcia Diaz
- Monica Gomez
- Monica Popescu
- Monica Recio Losilla
- Monica Rocco
- Monika Rothenfusser
- Montserrat Venturas Nieto
- Morena Milic
- Moris Rosati
- Moritoki Egi
- Morten Bestle
- Mrina Oikonomou
- Mu Jianhong
- Muhammed Elhadi
- Muhommed Ridwaan Syed
- Mukta Singh
- Murat Emre Tokur
- Muriel Fartoukh
- Mustafa Akker
- Mustafa Ay
- Na Jia
- Na Zhang
- Nadezhda Zubareva
- Nadine Flessel
- Nafseen Mostafa
- Nafseen Mostafa
- Nahla Ismail
- Nancy Hernandez-Sanchez
- Naraindath N Boedjawan
- Natalia Franco
- Natalia Hagau
- Natalia Monges
- Natalie Fox
- Natalie Remor
- Natalya Egorova
- Nathalie Fox
- Nathalie Gautheret
- Nathalie Heitzler
- Nawfel Ben-Hamouda
- Nayeli Rocio Cañas Padilla
- Nebia Peker
- Nehat Baftiu
- Neil Smith
- Nejc Umek
- Nelson Antunes
- Nerilee Baker
- Nestor Caicedo
- Neus Calpe
- Ngu Pei Hua
- Nicola Allison
- Nicola Horrigan
- Nicola McCann
- Nicola Vaughan-Jones
- Nicolas De Schryver
- Nie Bocui
- Niels Van Regenmortel
- Nigel White
- Nik Azman Nik Adib
- Nika Zorko
- Nikita Matiushkov
- Nikki Sarkar
- Nikolaj Kamenshchikov
- Nikolaos Kakaras
- Nikolaos Kazakos
- Nikolaos Pantelas
- Nikolina Udiljak
- Nina Kolbe
- Ning Li
- Nisha Bhandari Subedi
- Nivisha Parag
- Nobuaki Shime
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- Noryani Mohd Samat
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- Oktay Demirkiran
- Olakunle Idowu
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- Olga Farre
- Olga Ignatenko
- Oliva Matrona
- Orla Smith
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- Oscar Fernandez
- Oscar Fernández Rostello
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- Ourania Mousafiri
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- Oyebola Adekola
- Oyebola Adekola
- Ozcengiz Dilek
- Ozlem Ozkan Kuscu
- Pablo Garcia Olivares
- Pablo Julio Maldonaldo Bonsignore
- Pablo Lopez-Arcas Calleja
- Pablo Monedero
- Pablo Saul
- Pamela Rocha
- Panagiotis Ioannides
- Paola Araya
- Paolo Ciorba
- Paolo Cortellazi
- Paolo D'Ambrosio
- Paraskevi Alexandropoulou
- Pascal Beuret
- Pasquale Iozzo
- Patricia Albert
- Patricia Brizuela
- Patricia Delgado
- Patricia Gordon
- Patricia Wijnands
- Patrick Biston
- Patrick M Honore
- Patrick M Honore
- Patrick M Honoré
- Patrick Meybohm
- Patrick Toppin
- Paul Caddell
- Paul Eric Reyes
- Paul Hayden
- Paul Kuijpers
- Paul Pulak
- Paula Cabrita
- Paula Cristina Nogueira
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- Pauline Fivecoat
- Paulo Alves
- Paulo Carlos Garcia
- Pavlina Kleanthous
- Pedro Gutierrez
- Pedro Mogrovejo
- Pedro Silva
- Penny Parsons
- Peter Creber
- Peter Delve
- Peter Firment
- Peter Marko
- Peter Van Vliet
- Petr Piza
- Petra Crone
- Petra Polgarova
- Phil Broadhurst
- Philipp Douschan
- Philipp Eller
- Philipp Eller
- Philipp Simon
- Philippe Montravers
- Phumele Jali
- Pia Molina
- Pierina Arias Campos
- Pieter Hoste
- Pilar Martinez
- Pina Migliorino
- Pınar Karabacak
- Poe Poe Ei
- Poon Shing Tak
- Prabha Gautam
- Prabha Gautam
- Preveen Banwarie
- Prisca Olabisi Adejumo
- Prune Avogadro
- Przemyslaw Jasiewicz
- Purificacion Sanchez Zamora
- Qi Bo
- Qi Li
- Qi Zeng
- Qian Zhao
- Qiang Lin
- Qiao Yang
- Qin Fei
- Qing Feng Jiao
- Qing Li
- Qingli Zhao
- Qingping Huang
- Qiong Liang
- Qiong Ran
- Qun Xia Jiang
- Rachael Parke
- Rachael Parke
- Rachel Baumber
- Rachel Jarman
- Radmilo Jankovic
- Radmilo Jankovic
- Radmilo Jankovic
- Rafael Gonzalez
- Rafael Sierra
- Rajnish Saha
- Ramanathan Lakshmanan
- Ramon Molina Chueca
- Rand Butcher
- Rannveig J Jonasdottir
- Ranveig Lind
- Raquel Cavaco
- Raquel Garcia Alvarez
- Raquel Jimenez
- Rayanne Santos
- Raysa Cristina Schmidt
- Regina Martinez
- Regina Mulvey
- Reimer Riessen
- Renata Curic Radivojevic
- Reni Jacob
- René Favre
- René Schmutz
- Rhian Bull
- Rica Dagooc
- Ricardo Gregorio
- Richard Lebon
- Richard Whitticase
- Rihard Knafelj
- Rihard Knafelj
- Rik T Gerritsen
- Rima Song
- Rishi Ghosh
- Rita Foss Hargott
- Ritoo Kapoor
- Rob Wilting
- Robert Villa
- Robert Wise
- Roberto Gonzalez
- Rodney Rosalia
- Romina Esposito
- Romina Marconi
- Romuald Hentchoya
- Romuald Hentchoya
- Rong Fen Huang
- Rong Hua Zhao
- Ronghua Zhao
- Rongjun Ling Hu
- Rosa Del Bosque Diez
- Rosa Garcia
- Rosaleen Baruah
- Rosana Gabriela Escalante
- Rosanna Vaschetto
- Rosario Cosano
- Rosario Spina
- Rose Ekama Ilesanmi
- Rose Ilesanmi
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- Rosie Reece-Anthony
- Rosina Shayamano
- Ruben Fernandez
- RuiXia Wang
- Ruth Palfrey
- Ryohey Yamamoto
- Ryszard Gawda
- Sabah Abu Shawish
- Sabina Dhakal Pathak
- Sabrina Pelz
- Saeed Mahmood
- Saira Gomez
- Sait Karakurt
- Salma Kamoun
- Salvatore Girianni
- Salvatore Maurizio Maggiore
- Samantha Hagan
- Samantha North
- Samantha Smith
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- Sandra McPherson
- Sandrine Balon
- Sang-Miin Lee
- Sang-Min Lee
- Sanne Mikkelsen
- Santhana Kannan
- Sara Lospitao
- Sarah Bean
- Sarah Brumwell
- Sarah Buckley
- Sarah Farnell-Ward
- Sarah Grotheer
- Sarah Jane Turner
- Sarah Jones
- Sasha Sankar-Maharaj
- Satoru Hashimoto
- Saulius Vosylius
- Savino Spadaro
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sean Bagshaw
- Sebastian Geijer
- Sebastian Schüppel
- Sebastian Stehr
- Sema Turan
- Semih Aydemir
- Senay Goksu
- Seok Chan Kim
- Seok Jeong Lee
- Serap Avcı Ay
- Serdar Efe
- Sergio Reyes Iburrigarro
- Seung Yong Park
- Seval İzdes
- Seyed Mohammadreza Hashemian
- Shaly George
- Shanshan Lv
- Shanthi Ratnam
- Shanthi Ratnam
- Shanti Ratnam
- Shanti Rudra Deva
- Sharon McDowell-Skaines
- Shella Delossantos
- Shelley Schmollgruber
- Sherissa Microys
- Sherliza Wahab
- ShiFen Wu
- Shu Chuan Chang
- Shuchi Kaushik
- Shuhui Wang
- Shumin Jiang
- Shunsuke Taito
- Shunzhu Yang
- Shuo Wang
- Sibel Ocak Serin
- Silvia Angelica Jorge
- Silvia Call Manosa
- Silvia Calvino Günther
- Silvia Calvino-Gunther
- Silvia Calvino-Gunther
- Silvia Chaparro
- Silvia De Rosa
- Silvia Fernandez
- Silvie Allaert
- Silvina Bravo
- Silvio A Ñamendys-Silva
- Simant Jha
- Simeon Olanipekun
- Simeon Olanipekun
- Simon Dolenc
- Simon Mandaroux
- Simon Whiteley
- Simona Casaioli
- Sini John
- Siobhan O'Nuallain
- Siri Hansen
- Sirley Gill
- Siti Rohayah Sulaiman
- Siv Karin Malmin
- Siw Trudvang
- Slobodan Mihaljevic
- So Young Park
- Soad Imhmed R Alkhumsi
- Sofia Dias
- Sofia Kanakaki
- Sofia Putruele
- Sofia Zepoy
- Solenne Ory
- Sonia O Labeau
- Sonia Stiban
- Sonika Agarwal
- Sophie Liu
- Souheil Elatrous
- Souzana Anisoglou
- Srđan Gavrilovic
- Stacey Watts
- Stanislas Ledochowski
- Stefan Goller
- Stefan Schaller
- Stefano Coremans
- Stella Soundoulounaki
- Stella Uba
- Stephan Graeser
- Stephanie Harris
- Stephen Brett
- Stephen J Brett
- Stephen M Pastores
- Stijn I Blot
- Stijn Van de Velde
- Styliani Bastani
- Styliani Kourelea
- Suha Bozbay
- Sun Lijuan
- Sun Zhiping
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sundaresan Maiyalagan
- Sung Wai Ho
- Sunghoon Park
- Sunthiti Morakul
- Susana Ferreira
- Susana Pinto
- Susanna Hojden
- Susanne Fischer
- Suzana Bianchini
- Suzana Pečenković
- Suzanne Barrowcliffe
- Suzanne Bench
- Swagata Tripathy
- Swagotika Salo
- Sylvi Vullum
- Syragoula Tsikriki
- Sébastien Jochmans
- Sébastien Pili-Floury
- Taha Khaled
- Tai Sun Park
- Takoua Merhabene
- Talia Ben-Jacob
- Tamas Szakmany
- Tamas Vymazal
- Tanja Depuydt
- Tanja Goranovic
- Tao Zan
- Tara Clesi
- Tarek Dendane
- Tarja Tervo-Heikkinen
- Tatiana Patrichi
- Tatjana Beker
- Taís Pantaleao
- Teena Maguire
- Theogene Twagirumugabe
- Theogene Twagirumugabe
- Theonymfi Papavasilopoulou
- Thierry Dugernier
- Thomai Tholioti
- Thomas Dimski
- Thomas Leong
- Thomas Llewellym
- Tianfei Chen
- Ticiane Campanili
- Tien Meng Khoo
- Tim Chimunda
- Timothy Eng
- Tina Charlotte Bitsch Hansen
- Tina Damgaar Thomsen
- Tine Melgaard Frandsen
- Ting Han
- Tingting Li
- Tingting Yu
- Tobias Heinicke
- Tobias Odenthal
- Tobias Schulze
- Tom Dormans
- Tomas Jovaisa
- Tomas Jovaisa
- Tomas Vymazal
- Tomasz Torlinski
- Tomislav Mirkovic
- Tonia Onyeka
- Touraj Rastegar
- Treiza Trueman-Dawkins
- Trina Zhivotneva
- Troy Browne
- Turkay Akbas
- Ulf Guenther
- Ulla Kesti
- Ulla Sandberg
- Ulrica Mickelsson
- Ulrich Jaschinski
- Umeda Aya
- Una Gunter
- Uri Gorokhovatsky
- Uta Kolussi
- V Gusarov
- Vaarisan Ganeshalingam
- Vaibhav Bhargava
- Valentina Bendelari
- Valentina Di Gravio
- Vanda Seromenho
- Vanesa Mercado Telleria
- Vanesa Mercado Telleria
- Vanja Gievski
- Vanja Misic
- Vasileios Bekos
- Vasiliki Chantziara
- Vasilios Koulouras
- Vasilios Koulouras
- Veronica Curilen
- Veronika Kotanidi
- Vesna Bumbasirevic
- Vicent Salvà-Costa
- Victor Gonzalez
- Victoria Houghton
- Victoria Khoronenko
- Victoria Marriott
- Vilas Kushare
- Vincent Castelain
- Vincent Fraipont
- Vincianne Pleitinckx
- Virginie Souppart
- Virpi Lusenius
- Vishnu Das Sasidharan Nair
- Vitaly Gusarev
- Vitaly Gusarov
- Vitor Gomes
- Vitor Manuel Vaz Pinto
- Viveca Hamback Hellkvist
- Višnja Nesek Adam
- Vladimir Gurevich
- Vladimir Kulakov
- Vladislav Belskiy
- Volkan Inal
- Volodymyr Babych
- Vongayi Ogbeide
- W Nazaruddin W Hassan
- Walid Naija
- Walid Sellami
- Walter Swinnen
- Wan Nasrudin Wan Ismail
- Wang Zhijuan
- Wangari Waweru-Siika
- Wangari Waweru-Siika
- Wangyan Jin
- Wei Sun
- Wei Wang
- Wei Wei
- Wei Zhang
- Wei Zhang
- Weilian Yuan
- Weiwei Li
- Wenche Arntsen
- Wendy Brown
- Wendy Chaboyer
- Wendy Chaboyer
- Wendy Milner
- Wenjie Ju
- Wenmei Wang
- Wenmin Chen
- Wenwen Zhao
- Wenzhen Cao
- Wesal Ali Belkhair
- Willem Dieperink
- Windu Baskoro
- Won-Yeon Lee
- Wu Yuchen
- Xia Cui
- Xia Huang
- Xianhong Zheng
- Xianping Luo
- Xiao Fang Tian
- Xiao Xu
- XiaoChun Hu
- Xiaodi Liu
- Xiaofang Luo
- Xiaohan Li
- Xiaohan Li
- Xiaojun Wu
- Xiaoli Yan
- Xiaomin Wang
- Xiaoqiong Deng
- Xiaowu Bai
- Xiaoyan Chen
- Xiaoyan Chen
- Xiaoying Wu
- XiaoZhe Liu
- Ximena Villanueva
- Xingguo Li
- Xinhua Xia
- Xinhua Xia
- Xinjian Li
- Xinran Ding
- Xinxia Li
- Xinxia Li
- Xiuhua Fang
- Xiuhua Fang
- Xiujuan Xue
- XiuMei Liu
- Xiuying Yao
- Xiyan Wei
- Xu Peipei
- Xue Lin
- Xue Qin Li
- Xuejuan Liang
- XueLian Liu
- Xuelian Pang
- Xuelian Xu
- Xueping Jiao
- Yajun Ding
- Yakubu H Yakubu
- Yali Zhang
- Yalım Dikmen
- Yalım Dikmen
- Yalim Dikmen
- Yan Gao
- Yan Li
- Yan Liu
- Yan Liu
- Yan Long
- Yan Wan
- Yan Wang
- Yan Xiao
- Yan Xie
- Yan Xu
- Yan Yan
- Yanfei Long
- Yang Lei
- Yang Liu
- Yang Wu
- Yang Xiaoyan
- Yanhong Di
- Yanhua Hao
- Yani Tian
- Yanlan Yao
- Yanling Shen
- Yanman Jian
- Yanmei Gu
- Yanming Ding
- Yann Le Guen
- Yanping Yang
- Yasser Mandourah
- Yenny Cardenas
- Yenny Cardenas
- Yesim Serife Bayraktar
- Yin He
- Ying Cao
- Ying Li
- Ying Liu
- Ying Wang
- Ying Wei
- Ying Zhang
- Yingjuan Zhao
- Yingli Wang
- Yinhua Guo
- Yolanda Mendiara
- YongXia Yang
- Yoshimasa Nishime
- Yoshiro Hayashi
- Youjin Chang
- Youru Jiang
- Youssef Zied Elhechmi
- Ysica Acosta
- Yu Chao
- Yu Han
- Yu Liu
- Yu Liu
- Yue Sun
- Yue Ying Gong
- Yuming Zhou
- Yun Su Sim
- Yun Wu
- Yunchun Dong
- Yunfeng Xiong
- Yupeng Liu
- Yuping Wang
- Yuxia Huo
- Yuxia Wang
- Yuxia Yuan
- Yvan Fleury
- Yvonne Andersen
- Zainab Ateya
- Zaneta Bogoevska-Miteva
- Zeya Shi
- Zhang Zhigang
- ZhangShuangzi Li
- ZhangXia Feng
- Zhaoxia Feng
- Zhaoxing Dai
- Zhenxia Zhang
- Zhihong Chen
- Zhiru Yao
- Zhixia Jiang
- ZhiXia Jiang
- Zhixia Tian
- Zhu Jun Yu
- Zhuqing Li
- Zied Hajjej
- Zijing Wu
- Zsuzsann Ágoston
- Zu Qing Cao
- Zulkifli Zulkifli
- Ângela Lima
- Publication venue
- Intensive Care Medicine
- Publication date
- 29/08/2020
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
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- Alvarez Raquel Garcia
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- von Lewinski Dirk
- Vosylius Saulius
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- Wahab Sherliza
- Wahlbom Ewa
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- Watts Stacey
- Waweru-Siika Wangari
- Wei Dongfang
- Wei Wei
- Wei Xiyan
- Wei Ying
- Welters Ingeborg D.
- White Joanne
- White Nigel
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- Whitticase Richard
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- Wijnands Patricia
- Wilby Liz
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- Williams Lynne
- Wilting Rob
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- Wu Juan
- Wu ShiFen
- Wu Xiaojun
- Wu Xiaoying
- Wu Yang
- Wu Yun
- Wu Zijing
- Xhindi Nordian
- Xia Chun Jie
- Xia Xinhua
- Xiao Lina
- Xiao Min
- Xiao Yan
- Xiaoyan Yang
- Xie Yan
- Xing Cynthia
- Xiong Yunfeng
- Xixi Li
- Xu Lina
- Xu Xiao
- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
- Yang Lei
- Yang Qiao
- Yang Shunzhu
- Yang Yanping
- Yang YongXia
- Yao Xiuying
- Yao Yanlan
- Yao Zhiru
- Ye Man
- Ye Mei
- Yeni Nomhle Princess
- Yeon-Joo Lee
- Yildiz İsmail
- Yilmaz Hakan
- Yin Hai
- Yin Li
- Young Charlotte
- Young-Jae Cho
- Yu Jing
- Yu Min
- Yu Tingting
- Yu Zhu Jun
- Yuan Cui
- Yuan Weilian
- Yuan Yuxia
- Yuchen Wu
- Yuemen Ly
- Yumei Chen
- Zahra Hajer Ben
- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
- Zalba-Etayo Begoña
- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- 'Organisation for Economic Co-Operation and Development (OECD)'
- Publication date
- 26/02/2021
- Field of study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat
Recommended from our members
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
- Author
- Abdala Antonio
- Abidi Khalid
- Abillama Fayez François
- Abos Francisco Javier Saenz
- Aboufray Ahmed Ali
- Abregal Giancarlo
- Abroug Fekri
- Achilleos Eleni
- Acosta Ysica
- Adam Višnja Nesek
- Adamina Ileana
- Adams John
- Adamuz Jordi
- Adejumo Prisca Olabisi
- Adekola Oyebola
- Ademokun Jane
- Adenekan Anthony
- Adib Nik Azman Nik
- Adipa Faustina Excel
- Afonso Elsa
- Aganon Ferdinand
- Agarwal Sonika
- Aguirre Joaquin
- Aguirre Lydia Gallego
- Aguirre-Bermeo Hernan
- Ahmad Fatima Kasem El
- Ahmad Meraj
- Ahmed Hazem
- Ahn Jong-Joon
- Ahtiala Maarit
- Akbas Turkay
- Akdağ Devrim
- Akker Mustafa
- Akselsen Gro Ringstad
- Al-Alawi Maram Milud Said
- Alabuzidi Aya
- Alampi Daniela
- Albaiceta Guillermo Muñiz
- Albert Patricia
- Albrecht Lea
- Albrett Jonathan
- Alexandropoulou Paraskevi
- Alexandrou Anna
- Ali Ashwaq
- Ali Mohd Nazri
- Alias Anita
- Alkhumsi Soad Imhmed R.
- Allaert Silvie
- Allison Nicola
- Almekhlafi Ghaleb
- Alonso Helena Fernandez
- Alsheikhly Ahmed Subhy
- Alshrif Abdualhamid I
- Alvarenga Gloria
- Alvarez Diana
- Alvarez Gonzalo Martín
- Alvarez Gustavo Andres
- Alvarez Jorge Duerto
- Alvarez Josep Trenado
- Alvarez Raquel Garcia
- Alves Paulo
- Andersen Marit Hildegunn
- Andersen Yvonne
- Andresen Hanne
- Anisoglou Souzana
- Antonio Maria Gracia San
- Antunes Nelson
- Anvelt Eneli
- Aperocho Cristal April Jane
- Aponte Cesar
- Araya Paola
- Arcas María Luisa Bravo
- Arikan Huseyin
- Arntsen Wenche
- Arteta Arteta Donaldo S.
- Ashour Firas
- Assiri Amer
- Atchade Enora
- Ateya Zainab
- Attwood Ben
- Aucapina Alejandra
- Avalos Fernando
- Aves Emma
- Avogadro Prune
- Avramopoulou Lamprini
- Ay Mustafa
- Ay Serap Avcı
- Aya Umeda
- Ayala Maria
- Aydemir Semih
- Aydin Demet Tok
- Azencot Mazal
- Azoia Joao
- Baasanjav Battsetseg
- Babych Volodymyr
- Baccaro Fernando
- Badariotti Gustavo
- Bae Jung-Min
- Baek Jonghyun
- Baftiu Nehat
- Bagshaw Sean
- Bahrin Laila Kamaliah Kamalul
- Bai Dongmei
- Bai Xiaowu
- Baini Matías
- Bakas Apostolos
- Baker Helen
- Baker Nerilee
- Balasubramanian Madhu
- Balbay Abidin Oner
- Balon Sandrine
- Bantar Ana
- Banwarie Preveen
- Bao Guijun
- Baptiste-Savoie Jacqueline
- Barakat-Johnson Michelle
- Barefield Cindy
- Barkas Diane
- Barnes Christopher
- Barone Antonio
- Baronia Arvind
- Barr Louise
- Barreiro Emma Moreno
- Barros Elaine
- Barrowcliffe Suzanne
- Barrueco-Francioni Jesus Emilio
- Bartoli Julio Ricardo
- Baruah Rosaleen
- Bascary Carlos Alejandro
- Baskakov Danil
- Baskoro Windu
- Bastani Styliani
- Baumber Rachel
- Baxter Karen
- Bayraktar Yesim Serife
- Bealer Cheryl
- Bean Sarah
- Becker Cathy
- Becker Delmiro
- Behan Helena
- Beker Tatjana
- Bekos Vasileios
- Belii Adrian
- Belkhair Wesal Ali
- Belskiy Vladislav
- Ben-Hamouda Nawfel
- Ben-Jacob Talia
- Benbenishty Julie
- Bench Suzanne
- Bendelari Valentina
- Benlamin Mohamed
- Berry Gillian
- Bertoletti Fernando Pablo
- Besbes Lamia
- Besbes Lamia Ouanes
- Besch Guillaume
- Bestle Morten
- Beuret Pascal
- Bhakhtiani Lakshay
- Bhargava Vaibhav
- Bi AiPing
- Bianchini Suzana
- Bielskute Egidija
- Bilawicz Jan
- Binda Filipo
- Birgisdottir Hrönn
- Birgisdóttir Hrönn
- Bispo Bruno Miguel
- Biston Patrick
- Bjorgen Hege
- Blackwood Bronagh
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- Xiong Yunfeng
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- Xu Xuelian
- Xu Yan
- Xue Xiujuan
- Yaghi Aktham
- Yakubu Yakubu H.
- Yamamoto Ryohey
- Yan Howe
- Yan Xiaoli
- Yan Yan
- Yang Fan
- Yang Fengling
- Yang Huai
- Yang Jing
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- Zainudin Asmah
- Zakalik Graciela
- Zaki Ahmed
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- Zamora Purificacion Sanchez
- Zamorano Matias Jesús Flamm
- Zan Tao
- Zand Farid
- Zarei Fatemeh
- Zeng Jing Mei
- Zeng Qi
- Zepoy Sofia
- Zerman Avşar
- Zermeno Jorge Macias
- Zgrzheblovska Lesia
- Zhang Aizhi
- Zhang Baoke
- Zhang Feifei
- Zhang Guiping
- Zhang Hong
- Zhang Hongsu
- Zhang Hui
- Zhang Jing
- Zhang Jundi
- Zhang Libing
- Zhang Ling
- Zhang Na
- Zhang Wei
- Zhang Yali
- Zhang Ying
- Zhang Zhenxia
- Zhao Hui Min
- Zhao Lijuan
- Zhao Lina
- Zhao Qian
- Zhao Qingli
- Zhao Rong Hua
- Zhao Ronghua
- Zhao Wenwen
- Zhao Yingjuan
- Zhedaeva Marina
- Zheng Hong
- Zheng Jing
- Zheng Xianhong
- Zhigang Zhang
- Zhijuan Wang
- Zhiping Sun
- Zhivotneva Trina
- Zhou Yuming
- Zhu Guoyan
- Zhu JiFen
- Zhu Jin Yu
- Zivanovic-Posilovic Gordana
- Zorko Nika
- Zubareva Nadezhda
- Zuev Evgeniy
- Zueva Oksana
- Zulkifli Zulkifli
- Ágoston Zsuzsann
- Åkerman Eva
- Çelik Jale Bengi
- Ñamendys-Silva Silvio A.
- Özcan Beysim
- Özserezli Boğaç
- Ünlü Nurdan
- Čuljak Hemena
- Şentürk Evren
- Šuput Aleksandar
- Publication venue
- Intensive Care Medicine
- Publication date
- 09/04/2021
- Field of study
The original version of this article unfortunately contained a mistake
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
- Author
- Aaltonen M
- Abdur Rahman M
- Abell T
- Abide W. Jr
- Acheatel R
- Achiri P
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- Öner A
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND:
Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS:
We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization.
RESULTS:
During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events.
CONCLUSIONS:
Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)
Introduction to first issue from editors
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2022
- Field of study