The patatin-containing phospholipase A pPLAIIα modulates oxylipin formation and water loss in Arabidopsis thaliana

The patatin-related phospholipase A (pPLA) hydrolyzes membrane glycerolipids to produce monoacyl compounds and free fatty acids. Phospholipids are cleaved by pPLAIIα at the sn-1 and sn-2 positions, and galactolipids, including those containing oxophytodienoic acids, can also serve as substrates. Ablation of pPLAIIα decreased lysophosphatidylcholine and lysophosphatidylethanolamine levels, but increased free linolenic acid. pPLAIIα-deficient plants displayed a higher level of jasmonic acid and methyl jasmonate, as well as the oxylipin-biosynthetic intermediates 13-hydroperoxylinolenic acid and 12-oxophytodienoic acid than wild-type plants. The expression of genes involved in oxylipin production was also higher in the pPLAIIα-deficient mutant than in wild-type plants. The mutant plants lost water faster than wild type plants did. The stomata of wild type and mutant plants responded similarly to abscisic acid. In response to desiccation, the mutant and wild type leaves produced abscisic acid at the same rate, but after 4 h of desiccation, the jasmonic acid level was much higher in mutant than wild-type leaves. These results indicate that pPLAIIα negatively regulates oxylipin production and suggest a role in the removal of oxidatively modified fatty acids from membranes

The Radio - X-ray relation as a star formation indicator: Results from the VLA--E-CDFS Survey

In order to trace the instantaneous star formation rate at high redshift, and hence help understanding the relation between the different emission mechanisms related to star formation, we combine the recent 4 Ms Chandra X-ray data and the deep VLA radio data in the Extended Chandra Deep Field South region. We find 268 sources detected both in the X-ray and radio band. The availability of redshifts for $\sim 95$ of the sources in our sample allows us to derive reliable luminosity estimates and the intrinsic properties from X-ray analysis for the majority of the objects. With the aim of selecting sources powered by star formation in both bands, we adopt classification criteria based on X-ray and radio data, exploiting the X-ray spectral features and time variability, taking advantage of observations scattered across more than ten years. We identify 43 objects consistent with being powered by star formation. We also add another 111 and 70 star forming candidates detected only in the radio or X-ray band, respectively. We find a clear linear correlation between radio and X-ray luminosity in star forming galaxies over three orders of magnitude and up to $z \sim 1.5$. We also measure a significant scatter of the order of 0.4 dex, higher than that observed at low redshift, implying an intrinsic scatter component. The correlation is consistent with that measured locally, and no evolution with redshift is observed. Using a locally calibrated relation between the SFR and the radio luminosity, we investigate the L_X(2-10keV)-SFR relation at high redshift. The comparison of the star formation rate measured in our sample with some theoretical models for the Milky Way and M31, two typical spiral galaxies, indicates that, with current data, we can trace typical spirals only at z<0.2, and strong starburst galaxies with star-formation rates as high as $\sim 100 M_\odot yr^{-1}$, up to $z\sim 1.5$.Comment: 21 pages, 10 figures, 5 table

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity (<10[superscript -5] Hz[superscript –1/2]) and diffraction-limited resolution across a wide field of view.Allen Institute for Brain ScienceHoward Hughes Medical Institut

Associativity of a class of two-place functions and its consequences for classes of triangular norms

This article characterizes the associativity of two-place functions $T: [0,1]^2\rightarrow [0,1]$ defined by $T(x,y)=f^{(-1)}(F(f(x),f(y)))$ where $F:[0,1]^2\rightarrow[0,1]$ is a triangular norm (even a triangular subnorm), $f: [0,1]\rightarrow [0,1]$ is a strictly increasing function and $f^{(-1)}:[0,1]\rightarrow[0,1]$ is the pseudo-inverse of $f$. We prove that the associativity of functions $T$ only depends on the range of $f$, which is used to give a sufficient and necessary condition for the function $T$ being associative when the triangular norm $F$ is an ordinal sum of triangular norms and an ordinal sum of triangular subnorms in the sense of A. H. Clifford, respectively. These results finally are applied for describing classes of triangular norms generated by strictly increasing functions.2

A simulation study on the measurement of D0-D0bar mixing parameter y at BES-III

We established a method on measuring the \dzdzb mixing parameter $y$ for BESIII experiment at the BEPCII $e^+e^-$ collider. In this method, the doubly tagged $\psi(3770) \to D^0 \overline{D^0}$ events, with one $D$ decays to CP-eigenstates and the other $D$ decays semileptonically, are used to reconstruct the signals. Since this analysis requires good $e/\pi$ separation, a likelihood approach, which combines the $dE/dx$, time of flight and the electromagnetic shower detectors information, is used for particle identification. We estimate the sensitivity of the measurement of $y$ to be 0.007 based on a $20fb^{-1}$ fully simulated MC sample.Comment: 6 pages, 7 figure

The CDEX-1 1 kg Point-Contact Germanium Detector for Low Mass Dark Matter Searches

The CDEX Collaboration has been established for direct detection of light dark matter particles, using ultra-low energy threshold p-type point-contact germanium detectors, in China JinPing underground Laboratory (CJPL). The first 1 kg point-contact germanium detector with a sub-keV energy threshold has been tested in a passive shielding system located in CJPL. The outputs from both the point-contact p+ electrode and the outside n+ electrode make it possible to scan the lower energy range of less than 1 keV and at the same time to detect the higher energy range up to 3 MeV. The outputs from both p+ and n+ electrode may also provide a more powerful method for signal discrimination for dark matter experiment. Some key parameters, including energy resolution, dead time, decay times of internal X-rays, and system stability, have been tested and measured. The results show that the 1 kg point-contact germanium detector, together with its shielding system and electronics, can run smoothly with good performances. This detector system will be deployed for dark matter search experiments.Comment: 6 pages, 8 figure

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns