17 research outputs found
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019 : a systematic analysis from the Global Burden of Disease Study 2019
Background Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings Globally in 2019, 1.14 billion (95% uncertainty interval 1.13-1.16) individuals were current smokers, who consumed 7.41 trillion (7.11-7.74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27.5% [26. 5-28.5] reduction) and females (37.7% [35.4-39.9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0.99 billion (0.98-1.00) in 1990. Globally in 2019, smoking tobacco use accounted for 7.69 million (7.16-8.20) deaths and 200 million (185-214) disability-adjusted life-years, and was the leading risk factor for death among males (20.2% [19.3-21.1] of male deaths). 6.68 million [86.9%] of 7.69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation In the absence of intervention, the annual toll of 7.69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a dear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe
Search for patterns by combining cosmic-ray energy and arrival directions at the Pierre Auger Observatory
Energy-dependent patterns in the arrival directions of cosmic rays are searched for using data of the Pierre Auger Observatory. We investigate local regions around the highest-energy cosmic rays with E > = 6×1019 eV by analyzing cosmic rays with energies above E > = 5×1018 eV arriving within an angular separation of approximately 15°. We characterize the energy distributions inside these regions by two independent methods, one searching for angular dependence of energy-energy correlations and one searching for collimation of energy along the local system of principal axes of the energy distribution. No significant patterns are found with this analysis. The comparison of these measurements with astrophysical scenarios can therefore be used to obtain constraints on related model parameters such as strength of cosmic-ray deflection and density of point sources
Prototype muon detectors for the AMIGA component of the Pierre Auger Observatory
International audienceAMIGA (Auger Muons and Infill for the Ground Array) is an upgrade of the Pierre Auger Observatory to extend its range of detection and to directly measure the muon content of the particle showers. It consists of an infill of surface water-Cherenkov detectors accompanied by buried scintillator detectors used for muon counting. The main objectives of the AMIGA engineering array, referred to as the Unitary Cell, are to identify and resolve all engineering issues as well as to understand the muon-number counting uncertainties related to the design of the detector. The mechanical design, fabrication and deployment processes of the muon counters of the Unitary Cell are described in this document. These muon counters modules comprise sealed PVC casings containing plastic scintillation bars, wavelength-shifter optical fibers, 64 pixel photomultiplier tubes, and acquisition electronics. The modules are buried approximately 2.25 m below ground level in order to minimize contamination from electromagnetic shower particles. The mechanical setup, which allows access to the electronics for maintenance, is also described in addition to tests of the modules' response and integrity. The completed Unitary Cell has measured a number of air showers of which a first analysis of a sample event is included here
Muons In Air Showers At The Pierre Auger Observatory: Mean Number In Highly Inclined Events
We present the first hybrid measurement of the average muon number in air showers at ultrahigh energies, initiated by cosmic rays with zenith angles between 62\ub0 and 80\ub0. The measurement is based on 174 hybrid events recorded simultaneously with the surface detector array and the fluorescence detector of the Pierre Auger Observatory. The muon number for each shower is derived by scaling a simulated reference profile of the lateral muon density distribution at the ground until it fits the data. A 10^19\u2009\u2009eV shower with a zenith angle of 67\ub0, which arrives at the surface detector array at an altitude of 1450 m above sea level, contains on average (2.68\ub10.04\ub10.48(sys))
710^7 muons with energies larger than 0.3 GeV. The logarithmic gain dlnN\u3bc/dlnE of muons with increasing energy between 4
710^18\u2009\u2009eV and 5
710^19\u2009\u2009eV is measured to be (1.029\ub10.024\ub10.030(sys))
Limits to gauge coupling in the dark sector set by the non-observation of instanton-induced decay of Super-Heavy Dark Matter in the Pierre Auger Observatory data
We investigate instanton-induced decay processes of super-heavy dark matter particles produced during the inflationary epoch. Using data collected at the Pierre Auger Observatory we derive a bound on the reduced coupling constant of gauge interactions in the dark sector: , for . We show that this upper limit on is complementary to that obtained from the non-observation of tensor modes in the cosmic microwave background
Limits to gauge coupling in the dark sector set by the non-observation of instanton-induced decay of Super-Heavy Dark Matter in the Pierre Auger Observatory data
We investigate instanton-induced decay processes of super-heavy dark matter particles produced during the inflationary epoch. Using data collected at the Pierre Auger Observatory we derive a bound on the reduced coupling constant of gauge interactions in the dark sector: , for . We show that this upper limit on is complementary to that obtained from the non-observation of tensor modes in the cosmic microwave background
Limits to gauge coupling in the dark sector set by the non-observation of instanton-induced decay of Super-Heavy Dark Matter in the Pierre Auger Observatory data
We investigate instanton-induced decay processes of super-heavy dark matter particles produced during the inflationary epoch. Using data collected at the Pierre Auger Observatory we derive a bound on the reduced coupling constant of gauge interactions in the dark sector: , for . We show that this upper limit on is complementary to that obtained from the non-observation of tensor modes in the cosmic microwave background
Limits to gauge coupling in the dark sector set by the non-observation of instanton-induced decay of Super-Heavy Dark Matter in the Pierre Auger Observatory data
We investigate instanton-induced decay processes of super-heavy dark matter particles produced during the inflationary epoch. Using data collected at the Pierre Auger Observatory we derive a bound on the reduced coupling constant of gauge interactions in the dark sector: , for . We show that this upper limit on is complementary to that obtained from the non-observation of tensor modes in the cosmic microwave background