145 research outputs found

    Diferencias en el perfil reproductivo de mujeres autóctonas e inmigrantes residentes en Cataluña

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    ResumenObjetivoDescribir el perfil reproductivo en las mujeres autóctonas e inmigrantes residentes en Cataluña.MétodosLos abortos proceden del Registro de interrupción voluntaria del embarazo (IVE) del Departament de Salut, y los nacimientos y la población del Institut d’Estadística de Catalunya. Se han usado las variables «país de nacimiento» o «nacionalidad », según la fuente, para agrupar. Se analizan las tasas de fecundidad y aborto por edad, y las características sociodemográficas de las mujeres para el año 2005.ResultadosEl 20,8% de los 79.504 nacimientos y el 37,8% de las 16.798 IVE fueron de mujeres inmigrantes. El 14,2% de los embarazos de mujeres autóctonas y el 27,7% de los de mujeres inmigrantes terminan en aborto. Las tasa bruta de fecundidad y aborto es 1,4 y 3 veces superior, respectivamente, en las mujeres inmigrantes.ConclusionesHay importantes diferencias en las tasas y en las características sociodemográficas entre las mujeres autóctonas y las inmigrantes.AbstractObjectiveTo describe differences in reproductive patterns between autochthonous and immigrant women living in Catalonia (Spain).MethodsData on legal abortions were obtained from the abortions register in the Regional Ministry of Health, while data on births and the population were drawn from the Institute of Statistics of Catalonia. Depending on the source, the variables «country of birth» or «nationality» were used to compose the groups. Rates of fertility and abortion by age were computed for 2005 and the women's sociodemographic characteristics were analyzed.ResultsA total of 20.8% of the 79,504 births and 37.8% of the 16,798 abortions involved immigrant women, while 14.2% of pregnancies in autochthonous women and 27.7% of those in immigrant women terminated in abortion. Crude fertility and abortion rates were 1.4 and 3 times higher, respectively, in immigrant women.ConclusionsThere are important differences in abortion and fertility rates, as well as in social and demographic patterns, between autochthonous and immigrant women

    History of MeToo University movement in Spain

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    The precedents of the MeToo University movement, both in USA and Spain, has been led since the 1990s both by people who have taken a stand against sexual harassment in universities. The present study reflects the history of the MeToo University in Spain with an emphasis in the start of organized movement in 2013, also simultaneously with the one organized in the USA. For this purpose, in-depth interviews were conducted with people who led this transformation since its beginnings, as well as with others who have joined recently, in order to learn about the historical scope of this movement from a qualitative approach. Those people have suffered from isolating gender violence for daring to break the silence, being a loudspeaker and putting a name to a problem still silenced in Spanish universities and in the world. The movement has achieved great advances in academic settings, such as the obligation of all universities to have protocols for action in case of sexual harassment or gender violence, the legislation of isolating gender violence, and an unstoppable number of people who come out to tell their cases

    Effect of the inclusion of citrus pulp in the diet of goats on cheeses characteristics

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    The differences between the physicochemical (water content, water activity, pH, NaCl, fat, color, and texture) and sensory (descriptive analysis and consumer test) characteristics of cheeses made from the milk of goats fed on a typical control diet and goats fed on a diet incorporating orange pulp were compared. The addition of orange pulp leads to obtain cheeses(i) with a lower pH and water activity, but with a higher fat content, (ii) that are lighter and with a more yellowish-green hue and (iii) higher in color purity, hardness and adhesiveness, although they are less elastic and cohesive. Thus, the incorporation of orange pulp into the goat's diet affected not only the presence of holes in the cheese, but also its hardness, goat taste and salty taste, which were associated with a higher score of consumer acceptance. (C) 2014 Elsevier B.V. All rights reserved.The authors thank the panel of assessors for making themselves available and the Universitat Politecnica de Valencia for the financial support given throughout the Project PAID-05-12, SP20120723.Salvador Alcaraz, A.; Igual Ramo, M.; Contreras Monzón, CI.; Martínez Navarrete, N.; Camacho Vidal, MM. (2014). Effect of the inclusion of citrus pulp in the diet of goats on cheeses characteristics. Small Ruminant Research. 121(2-3):361-367. https://doi.org/10.1016/j.smallrumres.2014.06.012S3613671212-

    Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform

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    According to the World Health Organization, more than 1 billion people are at risk of or are affected by neglected tropical diseases. Examples of such diseases include trypanosomiasis, which causes sleeping sickness; leishmaniasis; and Chagas disease, all of which are prevalent in Africa, South America, and India. Our aim within the New Medicines for Trypanosomatidic Infections project was to use (1) synthetic and natural product libraries, (2) screening, and (3) a preclinical absorption, distribution, metabolism, and excretion\u2013toxicity (ADME-Tox) profiling platform to identify compounds that can enter the trypanosomatidic drug discovery value chain. The synthetic compound libraries originated from multiple scaffolds with known antiparasitic activity and natural products from the Hypha Discovery MycoDiverse natural products library. Our focus was first to employ target-based screening to identify inhibitors of the protozoan Trypanosoma brucei pteridine reductase 1 (TbPTR1) and second to use a Trypanosoma brucei phenotypic assay that made use of the T. brucei brucei parasite to identify compounds that inhibited cell growth and caused death. Some of the compounds underwent structure-activity relationship expansion and, when appropriate, were evaluated in a preclinical ADME-Tox assay panel. This preclinical platform has led to the identification of lead-like compounds as well as validated hits in the trypanosomatidic drug discovery value chain

    Significance of Cuscutain, a cysteine protease from Cuscuta reflexa, in host-parasite interactions

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    <p>Abstract</p> <p>Background</p> <p>Plant infestation with parasitic weeds like <it>Cuscuta reflexa </it>induces morphological as well as biochemical changes in the host and the parasite. These modifications could be caused by a change in protein or gene activity. Using a comparative macroarray approach <it>Cuscuta </it>genes specifically upregulated at the host attachment site were identified.</p> <p>Results</p> <p>One of the infestation specific <it>Cuscuta </it>genes encodes a cysteine protease. The protein and its intrinsic inhibitory peptide were heterologously expressed, purified and biochemically characterized. The haustoria specific enzyme was named cuscutain in accordance with similar proteins from other plants, e.g. papaya. The role of cuscutain and its inhibitor during the host parasite interaction was studied by external application of an inhibitor suspension, which induced a significant reduction of successful infection events.</p> <p>Conclusions</p> <p>The study provides new information about molecular events during the parasitic plant - host interaction. Inhibition of cuscutain cysteine proteinase could provide means for antagonizing parasitic plants.</p

    Simulating rewetting events in intermittent rivers and ephemeral streams: a global analysis of leached nutrients and organic matter

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    Climate change and human pressures are changing the global distribution and extent of intermittent rivers and ephemeral streams (IRES), which comprise half of the global river network area. IRES are characterized by periods of flow cessation, during which channel substrates accumulate and undergo physico‐chemical changes (preconditioning), and periods of flow resumption, when these substrates are rewetted and release pulses of dissolved nutrients and organic matter (OM). However, there are no estimates of the amounts and quality of leached substances, nor is there information on the underlying environmental constraints operating at the global scale. We experimentally simulated, under standard laboratory conditions, rewetting of leaves, riverbed sediments, and epilithic biofilms collected during the dry phase across 205 IRES from five major climate zones. We determined the amounts and qualitative characteristics of the leached nutrients and OM, and estimated their areal fluxes from riverbeds. In addition, we evaluated the variance in leachate characteristics in relation to selected environmental variables and substrate characteristics. We found that sediments, due to their large quantities within riverbeds, contribute most to the overall flux of dissolved substances during rewetting events (56‐98%), and that flux rates distinctly differ among climate zones. Dissolved organic carbon, phenolics, and nitrate contributed most to the areal fluxes. The largest amounts of leached substances were found in the continental climate zone, coinciding with the lowest potential bioavailability of the leached organic matter. The opposite pattern was found in the arid zone. Environmental variables expected to be modified under climate change (i.e. potential evapotranspiration, aridity, dry period duration, land use) were correlated with the amount of leached substances, with the strongest relationship found for sediments. These results show that the role of IRES should be accounted for in global biogeochemical cycles, especially because prevalence of IRES will increase due to increasing severity of drying events

    Estudos Luso-Hispanos de História do Direito

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    El primer volumen de los Estudios Luso-Hispanos de Historia del Derecho/ Estudos Luso-Hispanos de História do Direito recoge los trabajos presentados en el ámbito de la segunda edición del EHLHD (Encuentro Hispano-Luso de Historiadores del Derecho/Encontro Hispano-Luso de Historiadores do Direito), celebrado los días 6, 7 y 8 de julio de 2017 en la Universidad Autónoma de Madrid.Presentación / Laura Beck Varela y María Julia Solla Sastre (pp. 9-12). -- Quando il diritto era ancora compatto. Perché la storia giuridica svizzera è così diversa? / Pio Caroni (pp. 13-43). -- El derecho municipal medieval de la Cataluña Nueva (siglos XIII-XVII) / Josep Serrano Daura (pp. 45-62). -- Algunas consideraciones sobre el régimen local cantábrico frente al fomento naval y forestal en la Corona de Castilla (c.1560-1570) / Alfredo José Martínez González (pp. 63-91). -- Organização judiciária e administração da justiça no Portugal filipino: a “reformaçam da justiça” de Filipe I de Portugal (1582) / Jorge Veiga Testos (pp. 93-121). -- El oficio de secretario en la doctrina jurídica de la Edad Moderna / Marina Rojo Gallego-Burín (pp. 123-149). -- Notas sobre la reforma municipal carolina en Sevilla: la representación del común / María del Mar Tizón Ferrer (pp. 151-165). -- Un programa ilustrado para la formación de juristas. El Plan de Estudios de Pablo de Olavide de 1768 / Fernando Liendo Tagle (pp. 167-198). -- La formación del jurista en el virreinato del Perú en las postrimerías del antiguo régimen / Carlos Tormo Camallonga (pp. 199-237). -- Propiedad moderna y alteridad indígena en Brasil (1755-1862) / Camilla de Freitas Macedo (pp. 239-270). -- Direito, política e sociedade: as Novas Conquistas de Goa durante o Perismo. Os contributos de Nery Xavier e Cláudio Lagrange / Luís Pedroso de Lima Cabral de Oliveira y João Pedro Caleira (pp. 271-303). -- Horizonte nacional, espacio tradicional. La construcción jurídica de la nación y el extranjero en la constitución de Cádiz / Iván Pastoriza Martínez (pp. 305-337). -- La disolución de los consejos: entre quiebras, confusiones y continuidad (1834-1836) / Antonio Manuel Luque Reina (pp. 339-371). -- Justicia legal y derecho judicial: la influencia de la jurisprudencia en la formación de la ciencia jurídica isabelina / Blanca Sáenz de Santa María Gómez-Mampaso (pp. 373-409). -- Nuevas etiquetas disciplinares y sus contiendas: las ciencias políticas ante el derecho en Francia (1871-1900) / Pedro Luis López Herráiz (pp. 411-449). -- O casamento na legislação de 1910 em Portugal. A mudança de paradigma nas relações familiares / Miriam Afonso Brigas (pp. 451-479). -- Primeira Lei do Contrato de Trabalho em Portugal: Lei nº 1.952, de 10 de Março de 1937 / Margarida Seixas (pp. 481-513). -- A Revisão Constitucional de 1971: o Projecto de Lei 6/X da “Ala Liberal” num contexto de tensões internas no Marcelismo / Filipe de Arede Nunes (pp. 515-543)
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