227 research outputs found
Seleksi Induk Kambing Peranakan Etawah Berdasarkan Nilai Estimated Real Producingability Bobot Sapih di Kelompok Tani Margarini
Estimated Real Producing Ability (ERPA) value are maximally estimated of the ability of mother doe, which is allegedly based onexisting perfomans. Producing ability for production capability of an animal which is closelyrelated with the value of Repeatability, the average production, many production records, and the averageproduction within a population. Calculations of ERPA are entering information such asthe average mother inkidbirth production which compared with the average of herdmate production. Herdmate are all parents within thesame farm, who had kidbirth in the same relative time, but not the halfâ brother of a father.The research was conducted on May 2013 until June 2013 in Sungai Langka village, Subdistrict Gedong Tataan,Pesawaran District. This research using a survey method by analyzing production records the birth of the first andsecond of the 30 samples of doe Etawah crossbreed. Analysis was performed by searching for weaning weightcorrected, the estimated value Repeatability and the value of ERPA weaning weight in Margarini farmer groupsgoat.The result said that the average of corection weaning weight PE goat is 19,48±1,47 kg. The value of repeatabilityweaning weight PE Goat gotten in the research is 0,57 and the average of value ERPA weaning weight PE goat is19,84±1,067 kg. Base on the result of research known 20 of 30 goat (66,6 %) mother doe PE has ERPA above ofaverage
Noncovalent Interactions by QMC: Speedup by One-Particle Basis-Set Size Reduction
While it is empirically accepted that the fixed-node diffusion Monte-Carlo
(FN-DMC) depends only weakly on the size of the one-particle basis sets used to
expand its guiding functions, limits of this observation are not settled yet.
Our recent work indicates that under the FN error cancellation conditions,
augmented triple zeta basis sets are sufficient to achieve a benchmark level of
0.1 kcal/mol in a number of small noncovalent complexes. Here we report on a
possibility of truncation of the one-particle basis sets used in FN-DMC guiding
functions that has no visible effect on the accuracy of the production FN-DMC
energy differences. The proposed scheme leads to no significant increase in the
local energy variance, indicating that the total CPU cost of large-scale
benchmark noncovalent interaction energy FN-DMC calculations may be reduced.Comment: ACS book chapter, accepte
Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury
Background: Postnatal insulin-like growth factor-1 (IGF-1) replacement with recombinant human (rh)IGF-1 and IGF binding protein-3 (rhIGF-1/rhIGFBP-3) is being studied as a potential treatment to reduce comorbidities of prematurity. We have recently reported on a phase II, multicenter, randomized, controlled trial comparing postnatal rhIGF-1/rhIGFBP-3 replacement with standard of care (SOC) in extremely preterm infants (NCT01096784). Maximum severity of retinopathy of prematurity was the primary endpoint of the trial and presence of GMH-IVH/PHI one of the pre-specified secondary endpoints. Infants therefore received serial cranial ultrasound scans (CUS) between birth and term age. In this post-hoc analysis we present a detailed analysis of the CUS data of this trial and evaluate the effect of postnatal rhIGF-1/rhIGFBP-3 replacement on the incidence of different kinds of brain injury in extremely preterm infants.
Methods: This report is an exploratory post-hoc analysis of a phase II trial in which infants <28 weeks gestational age were randomly allocated to rhIGF-1/rhIGFBP-3 or SOC. Serial cranial ultrasounds were performed between birth and term-equivalent age. Presence of germinal matrix hemorrhage and intraventricular hemorrhage (GMH-IVH), periventricular hemorrhagic infarction (PHI), post-hemorrhagic ventricular dilatation, and white matter injury (WMI) were scored by two independent masked readers.
Results: The analysis included 117 infants; 58 received rhIGF-1/rhIGFBP-3 and 59 received SOC. A trend toward less grade IIâIII GMH-IVH and PHI was observed in treated infants vs. SOC. A subanalysis of infants without evidence of GMH-IVH at study entry (n = 104) showed reduced progression to GMH-IVH in treated infants (25.0% [13/52] vs. 40.4% [21/52]; not significant). No effects of rhIGF-1/rhIGFBP-3 on WMI were observed.
Conclusion: The potential protective effect of rhIGF-1/rhIGFBP-3 on the occurrence of GMH-IVH/PHI appeared most pronounced in infants with no evidence of GMH-IVH at treatment start
Feature Selection using Tabu Search with Learning Memory: Learning Tabu Search
International audienceFeature selection in classification can be modeled as a com-binatorial optimization problem. One of the main particularities of this problem is the large amount of time that may be needed to evaluate the quality of a subset of features. In this paper, we propose to solve this problem with a tabu search algorithm integrating a learning mechanism. To do so, we adapt to the feature selection problem, a learning tabu search algorithm originally designed for a railway network problem in which the evaluation of a solution is time-consuming. Experiments are conducted and show the benefit of using a learning mechanism to solve hard instances of the literature
Astrophysically Triggered Searches for Gravitational Waves: Status and Prospects
In gravitational-wave detection, special emphasis is put onto searches that
focus on cosmic events detected by other types of astrophysical observatories.
The astrophysical triggers, e.g. from gamma-ray and X-ray satellites, optical
telescopes and neutrino observatories, provide a trigger time for analyzing
gravitational wave data coincident with the event. In certain cases the
expected frequency range, source energetics, directional and progenitor
information is also available. Beyond allowing the recognition of gravitational
waveforms with amplitudes closer to the noise floor of the detector, these
triggered searches should also lead to rich science results even before the
onset of Advanced LIGO. In this paper we provide a broad review of LIGO's
astrophysically triggered searches and the sources they target
A Cross-correlation method to search for gravitational wave bursts with AURIGA and Virgo
We present a method to search for transient GWs using a network of detectors
with different spectral and directional sensitivities: the interferometer Virgo
and the bar detector AURIGA. The data analysis method is based on the
measurements of the correlated energy in the network by means of a weighted
cross-correlation. To limit the computational load, this coherent analysis step
is performed around time-frequency coincident triggers selected by an excess
power event trigger generator tuned at low thresholds. The final selection of
GW candidates is performed by a combined cut on the correlated energy and on
the significance as measured by the event trigger generator. The method has
been tested on one day of data of AURIGA and Virgo during September 2005. The
outcomes are compared to the results of a stand-alone time-frequency
coincidence search. We discuss the advantages and the limits of this approach,
in view of a possible future joint search between AURIGA and one
interferometric detector.Comment: 11 pages, 6 figures, submitted to CQG special issue for Amaldi 7
Proceeding
Evaluating feasibility and acceptability of a group WHO trans-diagnostic intervention for women with common mental disorders in rural Pakistan: a cluster randomised controlled feasibility trial (vol 28, pg 77, 2017)
In the above mentioned article [1] an author name was spelt incorrectly as M. V. OMMEREN. This has been corrected in the original to M. van Ommeren
Synergisitic role of ADP and Ca2+ in diastolic myocardial stiffness
Heart failure (HF) with diastolic dysfunction has been attributed to increased myocardial stiffness that limits proper filling of the ventricle. Altered cross-bridge interaction may significantly contribute to high diastolic stiffness, but this has not been shown thus far. Cross-bridge interactions are dependent on cytosolic [Ca2+] and the regeneration of ATP from ADP. Depletion of myocardial energy reserve is a hallmark of HF leading to ADP accumulation and disturbed Ca2+-handling. Here, we investigated if ADP elevation in concert with increased diastolic [Ca2+] promotes diastolic cross-bridge formation and force generation and thereby increases diastolic stiffness. ADP dose-dependently increased force production in the absence of Ca2+ in membrane-permeabilized cardiomyocytes from human hearts. Moreover, physiological levels of ADP increased actomyosin force generation in the presence of Ca2+ both in human and rat membrane-permeabilized cardiomyocytes. Diastolic stress measured at physiological lattice spacing and 37°C in the presence of pathologicallevels of ADP and diastolic [Ca2+] revealed a 76±1% contribution of cross-bridge interaction to total diastolic stress in rat membrane-permeabilized cardiomyocytes. Inhibition of creatine kinase (CK), which increases cytosolic ADP, in enzyme-isolated intact rat cardiomyocytes impaired diastolic re-lengthening associated with diastolic Ca2+- overload. In isolated Langendorff-perfused rat hearts, CK-inhibition increased ventricular stiffness only in the presence of diastolic [Ca2+]. We propose that elevations of intracellular ADP in specific types of cardiac disease, including those where myocardial energy reserve is limited, contribute to diastolic dysfunction by recruiting cross-bridges even at low Ca2+ and thereby increase myocardial stiffness
Status of coalescing binaries search activities in Virgo
The interferometric gravitational wave detector Virgo is undergoing an advanced phase of its commissioning, during which short runs are routinely performed, in which data are analyzed online and offline, searching for signals from coalescing binary systems. In this report we present the progress of the coalescing binaries search activities in Virgo, and we describe details of the detection pipeline including hardware injections, vetoes, and parameter estimation, using recent data taking
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