Terrestrial water storage changes over the Pearl River Basin from GRACE and connections with Pacific climate variability

AbstractTime-variable gravity data from the Gravity Recovery and Climate Experiment (GRACE) satellite mission are used to study terrestrial water storage (TWS) changes over the Pearl River Basin (PRB) for the period 2003–Nov. 2014. TWS estimates from GRACE generally show good agreement with those from two hydrological models GLDAS and WGHM. But they show different capability of detecting significant TWS changes over the PRB. Among them, WGHM is likely to underestimate the seasonal variability of TWS, while GRACE detects long-term water depletions over the upper PRB as was done by hydrological models, and observes significant water increases around the Longtan Reservoir (LTR) due to water impoundment. The heavy drought in 2011 caused by the persistent precipitation deficit has resulted in extreme low surface runoff and water level of the LTR. Moreover, large variability of summer and autumn precipitation may easily trigger floods and droughts in the rainy season in the PRB, especially for summer, as a high correlation of 0.89 was found between precipitation and surface runoff. Generally, the PRB TWS was negatively correlated with El Niño-Southern Oscillation (ENSO) events. However, the modulation of the Pacific Decadal Oscillation (PDO) may impact this relationship, and the significant TWS anomaly was likely to occur in the peak of PDO phase as they agree well in both of the magnitude and timing of peaks. This indicates that GRACE-based TWS could be a valuable parameter for studying climatic influences in the PRB

A parallel numerical algorithm by combining MPI and OpenMP programming models with applications in gravity field recovery

Satellite gravimetry missions have enabled the calculation of high-accuracy and high-resolution Earth gravity field models from satellite-to-satellite tracking data and gravitational gradients. However, calculating high maximum degree/order (e.g., 240 or even higher) gravity field models using the least squares method is time-consuming due to the vast amount of gravimetry observations. To improve calculation efficiency, a parallel algorithm has been developed by combining Message Passing Interface (MPI) and Open Multi-Processing (OpenMP) programming models to calculate and invert normal equations for the Earth gravity field recovery. The symmetrical feature of normal equations has been implemented to speed up the calculation progress and reduce computation time. For example, the computation time to generate the normal equation of an IGGT_R1 test version of degree/order 240 was reduced from 88 h to 27 h by considering the symmetrical feature. Here, the calculation was based on the high-performance computing cluster with 108 cores in the School of Geodesy and Geomatics, at Wuhan University. Additionally, the MPI parallel Gaussian-Jordan elimination method was modified to invert normal equation matrices and scaled up to 100 processor cores in this study while the traditional method was limited in a certain number of processors. Furthermore, the Cholesky decomposition from the ScaLAPACK library was used to compare with the parallel Gauss-Jordan elimination method. The numerical algorithm has effectively reduced the amount of calculation and sped up the calculation progress, and has been successfully implemented in applications such as building the gravity field models IGGT_R1 and IGGT_R1C.</p

Precise Hong Kong Geoid HKGEOID-2000

Abstract: This paper briefly discusses the data and methodology used in the construction of a Hong Kong local geoid of centimeter accuracy HKGEOID-2000. The results have been published in the website of Department of Land obtain the Surveying and Geo-Informatics, the Hong Kong Polytechnic University for public use. Users can directly geoidal height of a point by inputting its geodetic coordinates (in ITRF96 reference frame) or the HK1980 grid coordinates. Examples are given to illustrate the procedures

Altered fecal microbiome and correlations of the metabolome with plasma metabolites in dairy cows with left displaced abomasum

Left displaced abomasum (LDA) in postpartum dairy cows contributes to significant economic losses. Dairy cows with LDA undergo excessive lipid mobilization and insulin resistance. Although gut dysbiosis is implicated, little is known about the role of the gut microbiota in the abnormal metabolic processes of LDA. To investigate the functional links among microbiota, metabolites, and disease phenotypes in LDA, we performed 16S rDNA gene amplicon sequencing and liquid chromatography-tandem mass spectrometry (LC-MS/MS) of fecal samples from cows with LDA (n = 10) and healthy cows (n = 10). Plasma marker profiling was synchronously analyzed. In the LDA event, gut microbiota composition and fecal metabolome were shifted in circulation with an amino acid pool deficit in dairy cows. Compared with the healthy cows, salicylic acid derived from microbiota catabolism was decreased in the LDA cows, which negatively correlated with Akkermansia, Prevotella, non-esterified fatty acid (NEFA), and β-hydroxybutyric acid (BHBA) levels. Conversely, fecal taurolithocholic acid levels were increased in cows with LDA. Based on integrated analysis with the plasma metabolome, eight genera and eight metabolites were associated with LDA. Of note, the increases in Akkermansia and Oscillospira abundances were negatively correlated with the decreases in 4-pyridoxic acid and cytidine levels, and positively correlated with the increases in NEFA and BHBA levels in amino acid deficit, indicating pyridoxal metabolism-associated gut dysbiosis and lipolysis. Changes in branched-chain amino acids implicated novel host-microbial metabolic pathways involving lipolysis and insulin resistance in cows with LDA. Overall, these results suggest an interplay between host and gut microbes contributing to LDA pathogenesis

Sodium Fluoride Arrests Renal G2/M Phase Cell-Cycle Progression by Activating ATM-Chk2-P53/Cdc25C Signaling Pathway in Mice

Background/Aims: Excessive fluoride intake can induce cytotoxicity, DNA damage and cell-cycle changes in many tissues and organs, including the kidney. However, the underlying molecular mechanisms of fluoride-induced renal cell-cycle changes are not well understood at present. In this study, we used a mouse model to investigate how sodium fluoride (NaF) induces cell-cycle changes in renal cells. Methods: Two hundred forty ICR mice were randomly assigned to four equal groups for intragastric administration of NaF (0, 12, 24 and 48 mg/kg body weight/day) for 42 days. Kidneys were taken to measure changes of the cell-cycle at 21 and 42 days of the experiment, using flow cytometry, quantitative real-time polymerase chain reaction (qRT-PCR) and western blot methods. Results: NaF, at more than 12 mg/kg body weight, induced G2/M phase cell-cycle arrest in the renal cells, which was supported by the finding of significantly increased percentages of renal cells in the G2/M phase. We found also that G2/M phase cell-cycle arrest was accompanied by up-regulation of p-ATM, p-Chk2, p-p53, p-Cdc25C, p-CDK1, p21, and Gadd45a protein expression levels; up-regulation of ATM, Chk2, p53, p21, and Gadd45a mRNA expression levels; down-regulation of CyclinB1, mdm2, PCNA protein expression levels; and down-regulation of CyclinB1, CDK1, Cdc25C, mdm2, and PCNA mRNA expression levels. Conclusion: In this mouse model, NaF, at more than 12 mg/ kg, induced G2/M phase cell-cycle arrest by activating the ATM-Chk2-p53/Cdc25C signaling pathway, which inhibits the proliferation of renal cells and development of the kidney. Activation of the ATM-Chk2-p53/Cdc25C signaling pathway is the mechanism of NaF-induced renal G2/M phase cell-cycle arrest in this model

The oyster genome reveals stress adaptation and complexity of shell formation

The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads and a fosmid-pooling strategy, along with transcriptomes of development and stress response and the proteome of the shell. The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. Transcriptome studies reveal an extensive set of genes responding to environmental stress. The expansion of genes coding for heat shock protein 70 and inhibitors of apoptosis is probably central to the oyster's adaptation to sessile life in the highly stressful intertidal zone. Our analyses also show that shell formation in molluscs is more complex than currently understood and involves extensive participation of cells and their exosomes. The oyster genome sequence fills a void in our understanding of the Lophotrochozoa. © 2012 Macmillan Publishers Limited. All rights reserved

Pseudorapidity and transverse momentum dependence of flow harmonics in pPb and PbPb collisions

info:eu-repo/semantics/publishe

Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions

Peer reviewe

An embedding technique to determine ττ backgrounds in proton-proton collision data

An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe