Consortium Governance and Market Entry of Digital B2B Platforms: The Case of ADAMOS

False beliefs pose significant societal threats, including health risks, political polarization and even violence. In two studies (N = 884) we explored the efficacy of an individual-based approach to correcting false beliefs. We examined whether the character virtue of intellectual humility (IH)—an appreciation of one's intellectual boundaries— encourages revising one's false beliefs in response to counter-information. Our research produced encouraging but also mixed findings. Among participants who held false beliefs about the risks of vaccines (Study 1) and the 2020 US Election being rigged (Study 2), those with higher IH explored more information opposing these false beliefs. This exploration of opposing information, in turn, predicted updating away from these inaccurate health and political beliefs. IH did not directly predict updating away from false beliefs, however, suggesting that this effect—if it exists— may not be particularly powerful. Taken together, these results provide moderate support for IH as a character trait that can foster belief revision but, simultaneously, suggest that alternate pathways to combat false beliefs and misinformation may be preferred.publishedVersio

Erschließen von Freitextfeldern mittels Text Mining und die Qualität der gewonnenen Informationen

Vermehrt fallen innerhalb von Firmen neben den einfach auszuwertenden strukturierten Daten, auch unstrukturierte Daten in Form von Freitexten an. In dieser Ausarbeitung werden Techniken zur Strukturierung von Freitexten sowie verwandte Arbeiten und Vor- und Nachteile der Nutzung von Freitexten vorgestellt. Der Fokus liegt auf der Repräsentation der Daten als Vektoren und der Filterung von Stoppwörtern. Außerdem wird ein Prototyp zum Clustern von Freitextfeldern vorgestellt und auf einen Datensatz der NHTSA angewendet. Durch die Anwendung des Prototyps auf den NHTSA-Datensatz wird geklärt, inwiefern dieser Informationen in den Freitextfelder enthält, die nicht in den strukturierten Daten enthalten sind. Und ob das Clustering zu vollständigeren Informationen, das heißt zur erhöhter Datenqualität führt. Die Beantwortung geschieht durch Datenanalysen auf den vom Prototyp erweiterten Datensatz. Eine zusätzliche Anwendung und Auswertung des Prototyps, findet auf einen Datensatz aus der Industrie statt

Measurement of the cosmic ray spectrum above 4×10184{\times}10^{18} eV using inclined events detected with the Pierre Auger Observatory

A measurement of the cosmic-ray spectrum for energies exceeding $4{\times}10^{18}$ eV is presented, which is based on the analysis of showers with zenith angles greater than $60^{\circ}$ detected with the Pierre Auger Observatory between 1 January 2004 and 31 December 2013. The measured spectrum confirms a flux suppression at the highest energies. Above $5.3{\times}10^{18}$ eV, the "ankle", the flux can be described by a power law $E^{-\gamma}$ with index $\gamma=2.70 \pm 0.02 \,\text{(stat)} \pm 0.1\,\text{(sys)}$ followed by a smooth suppression region. For the energy ($E_\text{s}$) at which the spectral flux has fallen to one-half of its extrapolated value in the absence of suppression, we find $E_\text{s}=(5.12\pm0.25\,\text{(stat)}^{+1.0}_{-1.2}\,\text{(sys)}){\times}10^{19}$ eV.Comment: Replaced with published version. Added journal reference and DO

International criteria for electrocardiographic interpretation in athletes: Consensus statement.

Sudden cardiac death (SCD) is the leading cause of mortality in athletes during sport. A variety of mostly hereditary, structural or electrical cardiac disorders are associated with SCD in young athletes, the majority of which can be identified or suggested by abnormalities on a resting 12-lead electrocardiogram (ECG). Whether used for diagnostic or screening purposes, physicians responsible for the cardiovascular care of athletes should be knowledgeable and competent in ECG interpretation in athletes. However, in most countries a shortage of physician expertise limits wider application of the ECG in the care of the athlete. A critical need exists for physician education in modern ECG interpretation that distinguishes normal physiological adaptations in athletes from distinctly abnormal findings suggestive of underlying pathology. Since the original 2010 European Society of Cardiology recommendations for ECG interpretation in athletes, ECG standards have evolved quickly, advanced by a growing body of scientific data and investigations that both examine proposed criteria sets and establish new evidence to guide refinements. On 26-27 February 2015, an international group of experts in sports cardiology, inherited cardiac disease, and sports medicine convened in Seattle, Washington (USA), to update contemporary standards for ECG interpretation in athletes. The objective of the meeting was to define and revise ECG interpretation standards based on new and emerging research and to develop a clear guide to the proper evaluation of ECG abnormalities in athletes. This statement represents an international consensus for ECG interpretation in athletes and provides expert opinion-based recommendations linking specific ECG abnormalities and the secondary evaluation for conditions associated with SCD

Current state and challenges for dynamic metabolic modeling

While the stoichiometry of metabolism is probably the best studied cellular level, the dynamics in metabolism can still not be well described, predicted and, thus, engineered. Unknowns in the metabolic flux behavior arise from kinetic interactions, especially allosteric control mechanisms. While the stoichiometry of enzymes is preserved in vitro, their activity and kinetic behavior differs from the in vivo situation. Next to this challenge, it is infeasible to test the interaction of each enzyme with each intracellular metabolite in vitro exhaustively. As a consequence, the whole interacting metabolome has to be studied in vivo to identify the relevant enzymes properties. In this review we discuss current approaches for in vivo perturbation experiments, that is, stimulus response experiments using different setups and quantitative analytical approaches, including dynamic carbon tracing. Next to reliable and informative data, advanced modeling approaches and computational tools are required to identify kinetic mechanisms and their parameters.The authors EV, AT, KN, IR, MO, DM and AW are part of the ERA-IB funded consortium DYNAMICS (ERA-IB-14-081, NWO 053.80.724)

Academic patenting: the importance of industry support

This paper provides evidence that university-industry collaboration is important for turning commercial opportunities into patents. The results suggest that researchers who receive a large share of research grants from industry have a higher propensity to file a patent. Small dissemination grants generally exert a positive effect, whether they come from industry or not. It also finds that these interactions do not increase the number of industry owned patents alone but benefit universities’ commercialisation efforts in general

Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO