EFETIVIDADE DE UM PROGRAMA DE EXERCÍCIOS E TREINAMENTO NEUROMUSCULAR PARA PACIENTES COM A SÍNDROME DA DOR PATELOFEMORAL

A Síndrome da Dor Patelofemoral (SDPF) é uma das lesões mais comunsobservadas na prática ortopédica, correspondendo a 25% a 40% das afecções queacometem a articulação do joelho e afetando cerca de 26% da população em geral.Embora estejam presentes em uma ampla gama de indivíduos, a patologia éprevalente em pessoas mais jovens e ativas, principalmente em mulheres, que sãoafetadas cerca de duas vezes mais que os homens. A etiologia para desenvolvimentoda SDPF é multifatorial e está relacionada com alterações biomecânicas, excesso deatividade física, fraqueza dos músculos do joelho (quadríceps femoral), quadril (glúteomédio e máximo), patela alta e pé pronado. Diante do exposto, o objetivo do presentetrabalho foi verificar os resultados da aplicação de um programa de exercíciosresistidos e sensório motores para o tratamento de pacientes com diagnóstico deSDPF. Foi realizado um ensaio clínico com 20 pacientes do gênero feminino,fisicamente ativas, com a média de idade 25,8 (±7,4) anos, peso 61,1(±9,7) kg,estatura 163 (±5,5) cm, clinicamente diagnosticadas com SDPF. A pesquisa foidesenvolvida no Hospital Ortopédico de Medicina Especializada - HOME, CentroUniversitário de Brasília - UniCEUB e Instituto Trata Joelho e Quadril / DF. Aspacientes foram submetidas a 6 semanas de um programa de exercícios resistidos esensório motores para os músculos do tronco, abdutores e rotadores laterais dequadril e extensores de joelho. As sessões foram realizadas três vezes semana (n=18)e tinham por objetivo a melhora da força muscular, resposta neuromotora,coordenação e equilíbrio. Anteriormente e após o período de aplicação do programa,todas as participantes foram avaliadas em relação ao membro lesionado para o nível de dor (EVA), funcionalidade subjetiva (Escalas de Atividade de Vida Diária (EAVD) e Atividade Esportiva (EAE), força isométrica máxima dos músculos extensores de joelho, abdutores e rotadores laterais de quadril (dinamometria manual digital) e análise biomecânica 2D, mensurando o valgo dinâmico e a queda da pelve. Os resultados encontrados foram estatisticamente significativos para todas as variáveis (p0,0005). As queixas iniciais de dor diminuíram de 7 para 1 (p0,0001); a classificação funcional para as atividades de vida diária aumentou de 55 para 90 (p0,0001) e atividades esportivas de 50 para 82,5 (p0,0001); a força muscular aumentou de 25,6 para 35,0 (p0,0001) nos extensores de joelho, 19,1 para 24,8 (p0,0001) nos abdutores de quadril e 9,3 para 11,2 e rotadores laterais (p0,0001). A análise biomecânica demonstrou uma diminuição de 7,5° para 4,0° no valgo dinâmico (p0,0001) e de 4,0° para 2,5° na queda pélvica (p0,0001). Os resultados encontrados nos permitiram concluir que o programa de tratamento proposto promoveu a melhora da dor e funcionalidade dos pacientes, por meio do aumento da força muscular e melhora no padrão de movimento da cintura pélvica e membros inferiore

Eggplant crop in no tillage system under different irrigation depths

Este estudo foi conduzido no município de Seropédica, RJ, com o objetivo de se determinar, em cultivo orgânico e sistema de plantio direto, a produtividade da cultura da berinjela sob diferentes lâminas de irrigação e sistemas de cultivo (consorciada com leguminosa e solteira). O delineamento experimental adotado foi o de blocos ao acaso, no esquema de parcela subdividida com quatro repetições caracterizando, na parcela, os tratamentos equivalentes à lâmina de irrigação (40; 70; 100 e 120% ETc) e, na subparcela, os sistemas de cultivo consorciado com feijão caupi e solteiro. Ambos os sistemas de cultivo não influenciaram a produtividade final da berinjela; no entanto, considerando as diferentes lâminas, a maior produtividade comercial foi de 65,41 Mg ha-1, obtida para uma lâmina total de 690,04 mm (106,8% ETc). A menor lâmina aplicada resultou em qualidade inferior dos frutos em relação às maiores lâminas, sendo a taxa de descarte dos frutos de 3 e 14%, respectivamente, para a maior e a menor lâmina.This study was carried out in the municipality of Seropedica-RJ, in order to determine, under organic farming and no tillage system, the yield of eggplants under different irrigation depths and cropping systems (intercropped with legumes and alone). The experimental design was in randomized blocks in a split plot design with four replications. The plots were characterized by the treatments corresponding to different water depths (40, 70, 100, 120% ETc), and the sub plots, the intercropping systems with cowpea and eggplant alone. Cropping systems did not influence the final yield of eggplant. However, considering the different irrigation depths, the highest commercial yield (65.41 Mg ha(-1)) was obtained for a total depth of 690.04 mm (106.8% ETc). The lower applied depth provided lower quality of fruit compared with that observed in the higher depths. The rate of fruit discard was 3 and 14%, respectively, for the higher and lower depths of irrigation

Color parameters applied to pedotransfer functions in the estimation of soil attributes

Global demands for an increased food production have prompted scientists to create technological innovations in various segments of the agricultural and environmental sectors. The use of diffuse reflectance spectroscopy in soil color determination to estimate its attributes is an example of these advances. Thus, the aim of this research was to identify the potential of the three parameters of the Munsell color system (Hue, Value, and Chroma) in estimating different chemical and particle size attributes by pedotransfer functions in a Typic Hapludox in the Cerrado of Piauí State, Brazil. This soil showed a yellowish color due to the goethite and low contents of bases and organic carbon. Among the calibrated pedotransfer functions, we observed that phosphorus, aluminum, hydrogen, potential acidity, potential cation exchange capacity, and base saturation could be estimated by Hue, while clay content by Value, and Chroma used to estimate hydrogen, potential acidity, and cation exchange capacity. We conclude that the parameter color could be used to estimate soil attributes

Position statement of the Brazilian Academy of Rhinology on the use of antihistamines, antileukotrienes, and oral corticosteroids in the treatment of inflammatory sinonasal diseases

Introduction: Inflammatory conditions of the nose and paranasal sinuses are very prevalent in the general population, resulting in marked loss of quality of life in affected patients, as well as significant work, leisure, and social activity losses. These patients require specific and specialized treatment. A wide range of oral medications are available. Objective: The present document is aimed to clarify, for professionals treating patients with inflammatory sinonasal diseases, both specialists and general practitioners, specific oral therapies in noninfectious nasal inflammatory conditions. Methods: The methodology used to create this article included the search for the key words: oral corticosteroids, antihistamines, antileukotrienes, rhinitis, rhinosinusitis in the MEDLINE and EMBASE databases in the last 5 years. Since no relevant article was found for the text on the subject of interest in the last 5 years, the search was extended for another 5 years, and so on, according to the authors' needs. Results: Relevant literature was found regarding the use of antihistamines, antileukotrienes and oral corticosteroids in these conditions. The Brazilian Academy of Rhinology emphasizes, after extensive discussion by the collegiate, key points in the treatment with these drugs. Conclusion: There is support in the literature for the use of these drugshowever, final considerations about the role of each of them have been made. (C) 2017 Published by Elsevier Editora Ltda. on behalf of Associacao Brasileira de Otorrino-laringologia e Cirurgia Cervico-Facial.Univ Sao Paulo, Disciplina Otorrinolaringol, Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med, Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med, Dept Otorrinolaringol, Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Dept Otorrinolaringol, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Ciencias Saude, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Otorrinolaringol, Sao Paulo, SP, BrazilUniv Fed Minas Gerais, Fac Med, Belo Horizonte, MG, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Ribeirao Preto, SP, BrazilUniv Fed Bahia, Fac Med, Disciplina Otorrinolaringol, Salvador, BA, BrazilHosp Inst Paranaense Otorrinolaringol, Centro Rinite & Alergia, Curitiba, PR, BrazilUniv Estado Rio De Janeiro, Rio De Janeiro, RJ, BrazilUniv Brasilia, Fac Med, Brasilia, DF, BrazilUniv Fed Sao Paulo, Dept Otorrinolaringol & Cabeca & Pescoco, Sao Paulo, SP, BrazilUniv Luterana Brasil, Fac Med, Otorrinolaringol, Canoas, RS, BrazilMt Sinai Hosp, Dept Othorhinolaryngol, Toronto, ON, CanadaUniv Sao Paulo, Fac Med, Ciencias, Sao Paulo, SP, BrazilUniv Sao Paulo, Fac Med Ribeirao Preto, Dept Oftalmol Otorrinolaringol & Cirurgia Cabeca, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Ciencias Saude, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Otorrinolaringol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Otorrinolaringol & Cabeca & Pescoco, Sao Paulo, SP, BrazilWeb of Scienc

Ecossitema de Startups: um estudo das variáveis que compõem o contexto empreendedor maranhense

O artigo tem como objetivo: identificar as variáveis ​​que compõem o ecossistema de startups em São Luís - MA. O estudo busca responder ao problema: quais as principais variáveis ​​das startups no ecossistema São Luís - MA? O estudo foi realizado com uma amostra de 28 startups do cenário Maranhense de março a agosto de 2019. A pesquisa é de natureza quantitativa, onde foi realizada um levantamento de dados, com uso de um questionário adaptado do SEBRAE-PR. Os resultados demostram que esses modelos de negócio tem como órgão de maior as inciativas privadas, a dificuldade maior, sendo a falta de investimento, assim, os investimentos mais recebidos são pelos sócios investidores, os modelos de negócios mais utilizados, o SaaS (Software as a service uso de software por mensalidade) é o modelo de negócio em desenvolvido pela maioria das startups, as startups em sua maioria não participaram ou não se inscreveram para programa de aceleração, o problema a ser resolvido e a solução para o problema foram já estão validado e foram protótipados por maioria das startups participantes, a estrutura, o MPV e as métricas já estão definidas por maioria da startups e a solução já foi adquirida por 20 clientes

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected

Variability of systemic and oro-dental phenotype in two families with non-lethal Raine syndrome with FAM20C mutations

Background: Raine syndrome (RS) is a rare autosomal recessive bone dysplasia typified by osteosclerosis and dysmorphic facies due to FAM20C mutations. Initially reported as lethal in infancy, survival is possible into adulthood. We describe the molecular analysis and clinical phenotypes of five individuals from two consanguineous Brazilian families with attenuated Raine Syndrome with previously unreported features. Methods: The medical and dental clinical records were reviewed. Extracted deciduous and permanent teeth as well as oral soft tissues were analysed. Whole exome sequencing was undertaken and FAM20C cDNA sequenced in family 1. Results: Family 1 included 3 siblings with hypoplastic Amelogenesis Imperfecta (AI) (inherited abnormal dental enamel formation). Mild facial dysmorphism was noted in the absence of other obvious skeletal or growth abnormalities. A mild hypophosphataemia and soft tissue ectopic mineralization were present. A homozygous FAM20C donor splice site mutation (c.784 + 5 g > c) was identified which led to abnormal cDNA sequence. Family 2 included 2 siblings with hypoplastic AI and tooth dentine abnormalities as part of a more obvious syndrome with facial dysmorphism. There was hypophosphataemia, soft tissue ectopic mineralization, but no osteosclerosis. A homozygous missense mutation in FAM20C (c.1487C > T; p.P496L) was identified. Conclusions: The clinical phenotype of non-lethal Raine Syndrome is more variable, including between affected siblings, than previously described and an adverse impact on bone growth and health may not be a prominent feature. By contrast, a profound failure of dental enamel formation leading to a distinctive hypoplastic AI in all teeth should alert clinicians to the possibility of FAM20C mutations

Multicenter validation of PIM3 and PIM2 in Brazilian pediatric intensive care units

ObjectiveTo validate the PIM3 score in Brazilian PICUs and compare its performance with the PIM2.MethodsObservational, retrospective, multicenter study, including patients younger than 16 years old admitted consecutively from October 2013 to September 2019. We assessed the Standardized Mortality Ratio (SMR), the discrimination capability (using the area under the receiver operating characteristic curve – AUROC), and the calibration. To assess the calibration, we used the calibration belt, which is a curve that represents the correlation of predicted and observed values and their 95% Confidence Interval (CI) through all the risk ranges. We also analyzed the performance of both scores in three periods: 2013–2015, 2015–2017, and 2017–2019.Results41,541 patients from 22 PICUs were included. Most patients aged less than 24 months (58.4%) and were admitted for medical conditions (88.6%) (respiratory conditions = 53.8%). Invasive mechanical ventilation was used in 5.8%. The median PICU length of stay was three days (IQR, 2–5), and the observed mortality was 1.8% (763 deaths). The predicted mortality by PIM3 was 1.8% (SMR 1.00; 95% CI 0.94–1.08) and by PIM2 was 2.1% (SMR 0.90; 95% CI 0.83–0.96). Both scores had good discrimination (PIM3 AUROC = 0.88 and PIM2 AUROC = 0.89). In calibration analysis, both scores overestimated mortality in the 0%–3% risk range, PIM3 tended to underestimate mortality in medium-risk patients (9%–46% risk range), and PIM2 also overestimated mortality in high-risk patients (70%–100% mortality risk).ConclusionsBoth scores had a good discrimination ability but poor calibration in different ranges, which deteriorated over time in the population studied