79 research outputs found
Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells
- Author
- A Hall
- A Shor
- AA Abdul-Sater
- AA Abdul-Sater
- AA Abdul-Sater
- AJ Muller
- Andreas Hocke
- B Opitz
- B Opitz
- B Schmeck
- Bastian Opitz
- Bernd Schmeck
- C Basak
- C Buss
- CD Rothermel
- Christine Orlovski
- Claudia van Laak
- D Prantner
- David M. Ojcius
- DJ Lee
- DM Ojcius
- F Martinon
- F Martinon
- G Chen
- HB Yu
- IC Koo
- IE Brodsky
- IW Fong
- J Eitel
- J Harder
- Julia Eitel
- K Aktories
- K Bedard
- K Meixenberger
- K Shimada
- K Wennerberg
- Karolin Meixenberger
- KR Buchholz
- KW Wong
- L Arbibe
- L Gurcel
- L Van Aelst
- L Welter-Stahl
- M Krull
- M Maass
- M Witzenrath
- MG Netea
- NB Bryan
- Norbert Suttorp
- O Takeuchi
- P Broz
- P Saikku
- P Schotte
- Philippe Dje N'Guessan
- PM Hansbro
- R Munoz-Planillo
- RR Craven
- S Legrand-Poels
- S Mariathasan
- S Prebeck
- S Sasu
- SC Eisenbarth
- Stefan Hippenstiel
- V Hornung
- W Cheng
- X He
- Y Bulut
- Publication venue
- Public Library of Science
- Publication date
- 20/01/2012
- Field of study
Chlamydophila pneumoniae causes acute respiratory tract infections and has been associated with development of asthma and atherosclerosis. The production of IL-1β, a key mediator of acute and chronic inflammation, is regulated on a transcriptional level and additionally on a posttranslational level by inflammasomes. In the present study we show that C. pneumoniae-infected human mononuclear cells produce IL-1β protein depending on an inflammasome consisting of NLRP3, the adapter protein ASC and caspase-1. We further found that the small GTPase Rac1 is activated in C. pneumoniae-infected cells. Importantly, studies with specific inhibitors as well as siRNA show that Rac1 regulates inflammasome activation in C. pneumoniae-infected cells. In conclusion, C. pneumoniae infection of mononuclear cells stimulates IL-1β production dependent on a NLRP3 inflammasome-mediated processing of proIL-1β which is controlled by Rac1
Combined association of chronic disease and low skeletal muscle mass with physical performance in older adults in the Sarcopenia and Translational Aging Research in Taiwan (START) study
- Author
- A Pietrobelli
- BH Goodpaster
- C Rosano
- CC Lin
- Chao A Hsiung
- Cheng-Chieh Lin
- Chia-Ing Li
- Chih-Cheng Hsu
- Chih-Hsing Wu
- Ching-Yi Wang
- Ching-Yu Chen
- Chiu-Shong Liu
- CS Chang
- CY Wang
- D Legrand
- D Podsiadlo
- DL Waters
- EN Merriwether
- G Abellan van Kan
- H Andersen
- HL Taylor
- I Janssen
- IC Wu
- J Woo
- JS Lee
- KG Beenakker
- Kuo-Chin Huang
- LP Fried
- LW Organ
- M Cesari
- M Estrada
- M Navab
- MEM Ouden den
- NB Alexander
- ND Rekeneire
- PM Cawthon
- R Patil
- RR Kalyani
- RW Bohannon
- S Barbat-Artigas
- S Gillette-Guyonnet
- S Stenholm
- S Volpato
- SW Park
- Tsai-Chung Li
- V Bongard
- VA Hughes
- W Lutz
- Wen-Yuan Lin
- WH Pan
- Y Okura
- Y Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cutaneous wound healing: recruiting developmental pathways for regeneration
- Author
- A Augello
- A Bafico
- A Biernacka
- A Capon
- A Desmouliere
- A Desmouliere
- A Ghahary
- A Kim
- A Leask
- A Leask
- A Leask
- A Mauviel
- A Sanchez Alvarado
- A Scheid
- AJ Singer
- AJ Singer
- AK Langton
- AL Berrier
- AS Colwell
- AW Chua
- AW Seifert
- B Bandyopadhyay
- B Favier
- B Hinz
- B Mahdavian Delavary
- B St-Jacques
- BA Alman
- BA Hocevar
- BC Powell
- Benjamin A. Alman
- BH Porras-Reyes
- BJ Larson
- BM Carlson
- C Blanpain
- C Blanpain
- C Chiang
- C Ffrench-Constant
- C Gao
- C Margadant
- C McCusker
- C Niemann
- C Samakovlis
- C Soo
- C Vrijman
- CA Collins
- CC Yang
- CF Cheng
- CH Lee
- CK Sen
- CL Stoick-Cooper
- CP Denton
- CP Petersen
- CW Beck
- CW Beck
- DG McEwen
- DM Gardiner
- DM Ho
- E Quint
- E Schnapp
- E Tasouri
- EA O’Toole
- EJ Ezratty
- EK LeGrand
- EM Robertis De
- F Caiado
- F Grinnell
- F Verrecchia
- FM Watt
- FM Watt
- G Han
- G Han
- G Lin
- G Taylor
- GC Gurtner
- GL Brown
- GS Ashcroft
- GS Chin
- GS Schultz
- GS Schultz
- H Fujiwara
- H Le
- H Nishi
- H Yu
- HC Archbold
- HE Young
- HH Outtz
- HJ Snippert
- HP Lorenz
- HS Li-Korotky
- I Brownell
- I Cicha
- I Darby
- I Olivera-Martinez
- I Ono
- IC Poole Le
- J Asai
- J Berlanga-Acosta
- J Huelsken
- J Lilien
- J Ohtola
- J Shao
- J Thelu
- J Varga
- JA Hoffmann
- JA Pietenpol
- JD Luo
- JM Smiell
- JP Brockes
- K Foitzik
- K So
- KA Bielefeld
- KA Mace
- KB Jensen
- KD Poss
- Kirsten A. Bielefeld
- KJ Lavine
- KM Cadigan
- KM Yamada
- L Bruckner-Tuderman
- L Cooper
- L Karlsson
- L Santos-Ruiz
- L Wu
- LE Reynolds
- LR Solon
- M Athar
- M Dudas
- M Han
- M Ito
- M Ito
- M Kapoor
- M Kragl
- M Landstrom
- M Martinez-Ferrer
- M Moriyama
- M Sato
- M Shah
- M Sisco
- M Suzuki
- M Trojanowska
- M Wadman
- MB Labus
- MC Robson
- MJ Crowe
- MM Martino
- MP Alfaro
- MP Alfaro
- MR Duncan
- MW Ferguson
- N Harden
- N Yoshinari
- NA Coolen
- NL Occleston
- O Stojadinovic
- P Martin
- P Owens
- P Polychronopoulos
- PA Puolakkainen
- PT McCollum
- Q Wei
- R Atit
- R DasGupta
- R Grose
- R Okuyama
- R Poon
- RA Clark
- RAF Clark
- RB Widelitz
- RL McCallion
- RL Richardson
- RO Hynes
- RR Driskell
- RY Lin
- RY Lin
- S Amini Nik
- S Amini-Nik
- S Angers
- S Bai
- S Barrientos
- S Cheon
- S Chigurupati
- S Guo
- S Hehlgans
- S Roy
- S Werner
- S Woolner
- S Yazawa
- SA Nichols
- Saeid Amini-Nik
- SB Ting
- SR Childs
- SS Cheon
- SS Cheon
- SS Cheon
- SS Nakerakanti
- T Adell
- T Andl
- T Gridley
- T Okuse
- T Schreier
- TJ Brummel
- TL Tuan
- TS Alster
- TT Phan
- TY Lee
- U Gat
- V Levy
- V Miragliotta
- V Moulin
- VJ Mandracchia
- VK Mohan
- WJ Nelson
- X Fu
- Y Chen
- Y Kawakami
- Y Mu
- Y Yamaguchi
- Y Zhang
- YE Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
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- Aremu O
- Ariani F
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- Arnlov J
- Arowosegbe OO
- Aryal KK
- Arzani A
- Asaad M
- Asadi-Aliabadi M
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- Asgari S
- Asghari B
- Ashbaugh C
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- Atafar Z
- Athari SS
- Atnafu DD
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- Atre SR
- Atteraya MS
- Ausloos F
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- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
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- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
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- Baldasseroni A
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- Ball K
- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
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- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
- Barua L
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- Baune BT
- Bayati M
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- Bedi N
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- Bejot Y
- Bekuma TTT
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- Ben L
- Bender RG
- Bennett DA
- Bennitt FB
- Bensenor IM
- Benziger CP
- Berhe K
- Berman AE
- Bernabe E
- Bernstein RS
- Bertolacci GJ
- Bhagavathula AS
- Bhageerathy R
- Bhala N
- Bhandari D
- Bhardwaj P
- Bhat AG
- Bhattacharyya K
- Bhattarai S
- Bhutta ZA
- Bibi S
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- Biehl MH
- Bijani A
- Bikbov B
- Bilano V
- Bin Sayeed MS
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- Nikpoor AR
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- Norheim OF
- Norrving B
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- Nsoesie EO
- Nunez-Samudio V
- Oancea B
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- Oghenetega OB
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- Oladnabi M
- Olagunju AT
- Olusanya BO
- Olusanya JO
- Oluwasanu MM
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- Soofi M
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- Sreeramareddy CT
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- Sudaryanto A
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- Truelsen TC
- Tsai AC
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- Ullah I
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- Umeokonkwo CD
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- Upadhyay E
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- Venketasubramanian N
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- Wickramasinghe ND
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- Wijeratne T
- Wilner LB
- Wilson S
- Wiysonge CS
- Wojtyniak B
- Woldu G
- Wolfe CDA
- Wondmeneh TG
- Wondmieneh AB
- Wool EE
- Wozniak SS
- Wu A-M
- Wu C
- Wu J
- Wunrow HY
- Xie Y
- Xu G
- Xu R
- Yadgir S
- Yamada T
- Yamagishi K
- Yaminfirooz M
- Yano Y
- Yaya S
- Yazdi-Feyzabadi V
- Yearwood JA
- Yeheyis TY
- Yeshitila YG
- Yilgwan CS
- Yilma MT
- Yip P
- Yonemoto N
- Yoon S-J
- York HW
- Younis MZ
- Younker TP
- Yousefi B
- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
- Zhao Y
- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Arba AAK
- Aremu O
- Ariani F
- Aripov T
- Armoon B
- Arnlov J
- Arowosegbe OO
- Aryal KK
- Arzani A
- Asaad M
- Asadi-Aliabadi M
- Asadi-Pooya AA
- Asgari S
- Asghari B
- Ashbaugh C
- Assmus M
- Atafar Z
- Athari SS
- Atnafu DD
- Atout MMW
- Atre SR
- Atteraya MS
- Ausloos F
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
- Ayza MA
- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
- Bakkannavar SM
- Balachandran A
- Balakrishnan S
- Balalla S
- Balassyano S
- Baldasseroni A
- Bali AO
- Ball K
- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
- Bante SA
- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
- Barua L
- Barzegar A
- Basaleem H
- Bassat Q
- Basu S
- Baune BT
- Bayati M
- Baye BA
- Bazmandegan G
- Becker JS
- Bedi N
- Beghi E
- Behzadifar M
- Bejot Y
- Bekuma TTT
- Bell ML
- Bello AK
- Ben L
- Bender RG
- Bennett DA
- Bennitt FB
- Bensenor IM
- Benziger CP
- Berhe K
- Berman AE
- Bernabe E
- Bernstein RS
- Bertolacci GJ
- Bhagavathula AS
- Bhageerathy R
- Bhala N
- Bhandari D
- Bhardwaj P
- Bhat AG
- Bhattacharyya K
- Bhattarai S
- Bhutta ZA
- Bibi S
- Bicer BK
- Biehl MH
- Bijani A
- Bikbov B
- Bilano V
- Bin Sayeed MS
- Bin Zaman S
- Biondi A
- Birihane BM
- Bisanzio D
- Bisignano C
- Biswas RK
- Bitew H
- Bjorge T
- Bockarie MJ
- Bohlouli S
- Bohluli M
- Bojia HA
- Bolla SR
- Boloor A
- Boon-Dooley AS
- Borges G
- Borzi AM
- Borzouei S
- Bose D
- Bosetti C
- Boston S
- Boufous S
- Bourne R
- Brady OJ
- Braithwaite D
- Brauer M
- Brayne C
- Breitborde NJK
- Breitner S
- Brenner H
- Breusov AV
- Briant PS
- Briggs AM
- Briko AN
- Briko NI
- Britton GB
- Brugha T
- Bryazka D
- Buchbinder R
- Bumgarner BR
- Burkart K
- Burnett RT
- Busse R
- Butt ZA
- Caetano dos Santos FL
- Cahill LE
- Cahuana-Hurtado L
- Cai T
- Callender CSKH
- Camera LA
- Campos-Nonato IR
- Cao J
- Car J
- Car LT
- Cardenas R
- Carreras G
- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castaneda-Orjuela CA
- Castelpietra G
- Castle CD
- Castro E
- Castro F
- Catala-Lopez F
- Causey K
- Cederroth CR
- Cercy KM
- Cerin E
- Chalek J
- Chandan JS
- Chang AR
- Chang AY
- Chang J-C
- Chang K-L
- Charan J
- Charlson FJ
- Chattu VK
- Chaturvedi S
- Cherbuin N
- Chimed-Ochir O
- Chin KL
- Chirinos-Caceres JL
- Cho DY
- Choi J-YJ
- Christensen H
- Chu D-T
- Chung MT
- Chung S-C
- Cicuttini FM
- Ciobanu LG
- Cirillo M
- Cislaghi B
- Classen TKD
- Cohen AJ
- Collins EL
- Comfort H
- Compton K
- Conti S
- Cooper OR
- Corso B
- Cortesi PA
- Costa VM
- Cousin E
- Cowden RG
- Cowie BC
- Cromwell EA
- Croneberger AJ
- Cross DH
- Cross M
- Crowe CS
- Cruz JA
- Cummins S
- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Dai H
- Dai H
- Damasceno AAM
- Damiani G
- Dandona L
- Dandona R
- Daneshpajouhnejad P
- Dangel WJ
- Danielsson A-K
- Dargan PI
- Darshan BB
- Darwesh AM
- Daryani A
- Das Gupta R
- Das Neves J
- Das JK
- Dash AP
- Davey G
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- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
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- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
Narrow therapeutic index drugs: a clinical pharmacological consideration to flecainide
- Author
- A Carunchio
- A Khavandi
- AA Cohen
- AA Paola De
- AH Pietersen
- AJ Camm
- AJ Williams
- AR Harmer
- AW Nathan
- B Holmes
- B Katzung
- B Rocca
- BD Kahan
- BM Davit
- BP Grubb
- C Funck-Brentano
- C Köppel
- C Lafuente-Lafuente
- C Palmiere
- D Kiblboeck
- DE Hilleman
- DJ Schuirmann
- DM Roden
- DM Salerno
- DP Zipes
- DR Holmes
- DS Echt
- E Aliot
- E Aliot
- E Aliot
- EL Pritchett
- ES Vesell
- G Boriani
- G Mikus
- G Steinbeck
- GJ Conard
- GJ Conard
- GR Wilkinson
- GV Naccarelli
- GV Naccarelli
- H Almroth
- HJ Crijns
- HJ Duff
- HL Kennedy
- HS Blix
- I Sihm
- IC Gelder Van
- J Braun
- J Coromilas
- J Morganroth
- J Tamargo
- JA Reiffel
- JA Reiffel
- JA Reiffel
- Jean-Yves Le Heuzey
- JL Anderson
- JL Anderson
- JL Anderson
- JL Anderson
- JL Anderson
- JP Balthasar
- JR Peters
- Juan Tamargo
- K Doki
- K Doki
- K Doki
- KA Muhiddin
- KJ Hellestrand
- KJ Hellestrand
- KS Lim
- L Bertilsson
- L Endrenyi
- L Hendeles
- L Tennezé
- LCA D’Alessandro
- LM Wijk Van
- M Chimienti
- M Gulizia
- M Hodges
- M Homma
- M Hottinger
- M Restivo
- M Wehling
- MA Josephson
- N Freemantle
- NA Estes
- P Coumel
- P Meredith
- Phillipe Mabo
- PL Friedman
- PW Serruys
- R Taylor
- RE Parker
- RH Falk
- RJ Beyth
- RJ Kasmer
- RK Verbeeck
- RL McNamara
- RL Woosley
- S Nattel
- S Ranger
- SC Forland
- SC Forland
- SH Hohnloser
- SM Ting
- SS Andersen
- T Ozahowski
- V Fuster
- V Legrand
- X Zhang
- YY Tsao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study
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- Abbasi-Kangevari M
- Abdi A
- Abedi A
- Aboyans V
- Abrha WA
- Abu-Gharbieh E
- Abushouk AI
- Acharya D
- Adair T
- Addolorato G
- Addolorato G
- Adebayo OM
- Ademi Z
- Advani SM
- Afshari K
- Afshin A
- Agarwal G
- Agasthi P
- Ahmad S
- Ahmadi S
- Ahmed MB
- Aji B
- Akalu Y
- Akande-Sholabi W
- Aklilu A
- Akunna CJ
- Al-Eyadhy A
- Al-Raddadi RM
- Alahdab F
- Alhabib KF
- Alif SM
- Alipour V
- Aljunid SM
- Alla F
- Almasi-Hashiani A
- Almustanyir S
- Amegah AK
- Amini S
- Aminorroaya A
- Ammirati E
- Ammirati E
- Amu H
- Amugsi DA
- Ancuceanu R
- Anderlini D
- Andrei CL
- Andrei T
- Ansari-Moghaddam A
- Anteneh ZA
- Antonazzo IC
- Antony B
- Anwer R
- Appiah LT
- Arabloo J
- Artanti KD
- Ataro Z
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- Avila-Burgos L
- Awan AT
- Awoke MA
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- Ayza MA
- Azari S
- B DB
- Baddour LM
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- Baheiraei N
- Baig AA
- Bakhtiari A
- Banach M
- Banik PC
- Baptista EA
- Barboza MA
- Barengo NC
- Barengo NC
- Barua L
- Basu S
- Beaton A
- Beaton AZ
- Bedi N
- Benjamin EJ
- Benjamin EJ
- Bennett DA
- Bensenor IM
- Benziger CP
- Benziger CP
- Berman AE
- Bezabih YM
- Bhagavathula AS
- Bhaskar S
- Bhattacharyya K
- Bijani A
- Bikbov B
- Birhanu MM
- Boloor A
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- Briko NI
- Brodmann M
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- Butt ZA
- Béjot Y
- Caetano dos Santos FL
- Cahill LE
- Cahill TJ
- Cahill TJ
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- Campos-Nonato IR
- Cantu-Brito C
- Car J
- Carapetis J
- Carapetis JR
- Carrero JJ
- Carvalho F
- Castañeda-Orjuela CA
- Catalá-López F
- Catapano AL
- Catapano AL
- Cerin E
- Charan J
- Chattu VK
- Chen S
- Chin KL
- Choi J-YJ
- Chu D-T
- Chugh S
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- Cooper LT
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- Coresh J
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- Costa VM
- Criqui M
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- Cundiff DK
- Cámera LA
- Dadras O
- Dagnew B
- Dai X
- Damasceno AAM
- Dandona L
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- Davletov K
- De la Cruz-Góngora V
- De la Hoz FP
- De Neve J-W
- DeCleene N
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- Denova-Gutiérrez E
- Derbew Molla M
- Derseh BT
- Desai R
- Deuschl G
- Dharmaratne SD
- Dhimal M
- Dhungana RR
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- Diaz D
- Djalalinia S
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- Douiri A
- Duncan BB
- Duraes AR
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- Eagle KA
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- Ebtehaj S
- Eftekhari A
- Eftekharzadeh S
- Ekholuenetale M
- El Nahas N
- El-Jaafary SI
- Elgendy IY
- Elhadi M
- Emmons-Bell S
- Emmons-Bell S
- Esteghamati S
- Etisso AE
- Eyawo O
- Fadhil I
- Faraon EJA
- Faris PS
- Farwati M
- Farzadfar F
- Feigin VL
- Feigin VL
- Fernandes E
- Fernandez Prendes C
- Fernández-Sola J
- Fernández-Solà J
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- Filip I
- Fischer F
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- Gebremeskel GG
- Getacher L
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- Ghashghaee A
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- Gill PS
- Gillum RF
- Glushkova EV
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- Humayun A
- Iavicoli I
- Ibeneme CU
- Ibitoye SE
- Ilesanmi OS
- Ilic IM
- Ilic MD
- Inker L
- Inker L
- Iqbal U
- Irvani SSN
- Islam RM
- Iso H
- Iwagami M
- Jain V
- Javaheri T
- Jayapal SK
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- Jeemon P
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- Johnson CO
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- Kamath A
- Kamel I
- Kandel A
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- Karch A
- Karthikeyan G
- Karthikeyan G
- Kasa AS
- Kassebaum N
- Kassebaum NJ
- Katoto PDMC
- Kayode GA
- Khader YS
- Khammarnia M
- Khan EA
- Khan M
- Khan MN
- Khan MS
- Khatab K
- Kibria GMA
- Kim GR
- Kim YJ
- Kimokoti RW
- Kisa A
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- Kivimäki M
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- Koroshetz W
- Koroshetz WJ
- Korshunov VA
- Koulmane Laxminarayana SL
- Koyanagi A
- Krishan K
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- Kucuk Bicer B
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- Kumar GA
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- Kurmi OP
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- Lim L-L
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- Lin H
- Lin R-T
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- Lorkowski S
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- Martini S
- Mathur MR
- Mazzaglia G
- Mehata S
- Mehndiratta MM
- Meier T
- Menezes RG
- Mensah GA
- Mensah GA
- Meretoja A
- Mestrovic T
- Miazgowski B
- Miazgowski T
- Michalek IM
- Miller TR
- Mirijello A
- Mirijello A
- Mirrakhimov EM
- Mirzaei H
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- Mohammad DK
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- Moran AE
- Morawska L
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- Nagarajan AJ
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- Patel UK
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- Rahman Muhammad
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- Rajagopalan S
- Rajagopalan S
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- Ranasinghe P
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- Rathi P
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- Samy AM
- Santos IS
- Santric-Milicevic MM
- Sarrafzadegan N
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- Schmidt MI
- Schutte AE
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- Shahabi S
- Shahid I
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- Shariful Islam Sheikh
- Shawon MSR
- Sheikh A
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- Shin JI
- Shin M-J
- Shiri R
- Shiue I
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- Siddiqi TJ
- Silva DAS
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- Skryabina AA
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- Sliwa-Hahnle K
- Soheili A
- Spurlock EE
- Stark B
- Stark BA
- Stockfelt L
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- Stranges S
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- Teklehaimanot BF
- Temesgen AM
- Temsah M-H
- Tesema AK
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- Timalsina B
- Timpel P
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- Tleyjeh II
- Tleyjeh IM
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- Tripathi A
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- Truelsen TC
- Tsegay GM
- Tsegaye GW
- Tsilimparis N
- Tusa BS
- Tyrovolas S
- Umapathi KK
- Unim B
- Unnikrishnan B
- Ur Rahman MH
- Usman MS
- Vaduganathan M
- Valdez PR
- Valgimigli M
- Valgimigli M
- Vasankari TJ
- Velazquez DZ
- Venketasubramanian N
- Vos T
- Vos T
- Vu GT
- Vujcic IS
- Waheed Y
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- Weintraub RG
- Weldemariam AH
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- Whelton PK
- Whelton PK
- Winkler AS
- Wiysonge CS
- Wolfe CDA
- Wubishet BL
- Xu G
- Yacoub M
- Yacoub M
- Yadollahpour A
- Yamagishi K
- Yan LL
- Yandrapalli S
- Yano Y
- Yatsuya H
- Yeheyis TY
- Yeshaw Y
- Yilgwan CS
- Yonemoto N
- Yu C
- Yusefzadeh H
- Zachariah G
- Zaman MS
- Zaman SB
- Zamanian M
- Zand R
- Zandifar A
- Zarghi A
- Zastrozhin MS
- Zastrozhina A
- Zhang W
- Zhang Y
- Zhang Z-J
- Zhong C
- Zou Z
- Zuhlke L
- Zuhlke LJ
- Zuniga YMH
- Ärnlöv J
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019.
Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019.
Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases
Sulphate-climate coupling over the past 300,000 years in inland Antarctica
- Author
- B Delmonte
- BA Bodhaine
- EW Wolff
- F Lambert
- G Winckler
- Hideaki Motoyama
- IC Tsai
- MO Andreae
- Motohiro Hirabayashi
- MR Legrand
- O Watanabe
- P Kaufmann
- PK Quinn
- PT Manktelow
- R Röthlisberger
- R Röthlisberger
- RJ Charlson
- Ryu Uemura
- T Sakurai
- Takayuki Miyake
- Takeo Hondoh
- Toshitaka Suzuki
- U Lohmann
- V Masson-Delmotte
- Y Fujii
- Y Fujii
- Y Iizuka
- Y Iizuka
- Y Iizuka
- Y Iizuka
- Yoshinori Iizuka
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 04/10/2012
- Field of study
Perioperative acute kidney injury: What’s new?
- Author
- A Bihorac
- A Kulier
- A Zangrillo
- A Zarbock
- AC Gordon
- AX Garg
- B Redfors
- BT Thompson
- C Ronco
- CS Wilcox
- D d Payen
- EA Hoste
- FJ Abelha
- G Bragadottir
- H Mao
- H Masoomi
- I Knezevic
- IC Vermeulen Windsant
- J Kooiman
- JA Kellum
- JA Russell
- JG Abuelo
- JL Alge
- JL Carson
- JL Xue
- JM Arthur
- JS McDonald
- K Fukazawa
- K Karkouti
- K Karkouti
- K Kateros
- LB Holst
- LE Crowley
- LI Goldberg
- LS Chawla
- M Legrand
- M Legrand
- M Legrand
- M Legrand
- M Legrand
- M Meersch
- M Opperer
- M Ostermann
- M Tagawa
- M. Coutrot
- M. Legrand
- MH Rosner
- N Brienza
- NM Yunos
- P Asfar
- PJ Devereaux
- R Yacoub
- R Zarychanski
- RH Thiele
- S Kheterpal
- SY Li
- SY Pan
- T Bove
- ZH Endre
- ZZ Niu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Applying genetic improvement to a genetic programming library in C++
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …