Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.

BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. METHODS: The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, survey, police, and surveillance data. GBD 2017 added ten VA studies, 127 country-years of VR data, 502 cancer-registry country-years, and an additional surveillance country-year. Expansions of the GBD cause of death hierarchy resulted in 18 additional causes estimated for GBD 2017. Newly available data led to subnational estimates for five additional countries-Ethiopia, Iran, New Zealand, Norway, and Russia. Deaths assigned International Classification of Diseases (ICD) codes for non-specific, implausible, or intermediate causes of death were reassigned to underlying causes by redistribution algorithms that were incorporated into uncertainty estimation. We used statistical modelling tools developed for GBD, including the Cause of Death Ensemble model (CODEm), to generate cause fractions and cause-specific death rates for each location, year, age, and sex. Instead of using UN estimates as in previous versions, GBD 2017 independently estimated population size and fertility rate for all locations. Years of life lost (YLLs) were then calculated as the sum of each death multiplied by the standard life expectancy at each age. All rates reported here are age-standardised

A new and convenient route to synthesis of enynones and dienones from TosMIC

Dilithio- and disodiotosylmethylisocyanides react with pyridine N-oxide and pyridazine N-oxide leading to formation of ring opened unsaturated products which on reaction with aralkyl halides and further hydrolysis result in formation of dienones and enynones respectively

Multiplicity and pseudorapidity distribution of photons in S+Au reaction at 200A GeV

The photon multiplicity has been measured for the first time in S+Au collisions at 200A GeV over a wide pseudorapidity range (2.8 less than or equal to eta less than or equal to 5.2) employing a fine granularity preshower detector. The pseudorapidity density of photons increases with centrality, reaching similar to 200 at the highest centrality studied. The results are compared with measurements of the charged particle multiplicity and with predictions of the VENUS event generator

Soft photon production in central 200 GeV nucleon S-32+Au collisions

Inclusive photons of low transverse momenta have been measured in 200 GeV/nucleon S-32+Au collisions at the CERN SPS. Data were taken in the WA93 experiment using a small acceptance BGO detector with longitudinal segmentation. The results are compared to WA80 measurements for the same system and results from hadron decay calculations, An excess of soft photons over the expectations from neutral meson decays is observed

Additional file 4 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Additional file 4: Supplemental results.1. README. 2. Prevalence range across districts. 3. Prevalence range between sexes. 4. Prevalence range between ages. 5. Age-specific district ranges