Flame Enhancement and Quenching in Fluid Flows

We perform direct numerical simulations (DNS) of an advected scalar field which diffuses and reacts according to a nonlinear reaction law. The objective is to study how the bulk burning rate of the reaction is affected by an imposed flow. In particular, we are interested in comparing the numerical results with recently predicted analytical upper and lower bounds. We focus on reaction enhancement and quenching phenomena for two classes of imposed model flows with different geometries: periodic shear flow and cellular flow. We are primarily interested in the fast advection regime. We find that the bulk burning rate v in a shear flow satisfies v ~ a*U+b where U is the typical flow velocity and a is a constant depending on the relationship between the oscillation length scale of the flow and laminar front thickness. For cellular flow, we obtain v ~ U^{1/4}. We also study flame extinction (quenching) for an ignition-type reaction law and compactly supported initial data for the scalar field. We find that in a shear flow the flame of the size W can be typically quenched by a flow with amplitude U ~ alpha*W. The constant alpha depends on the geometry of the flow and tends to infinity if the flow profile has a plateau larger than a critical size. In a cellular flow, we find that the advection strength required for quenching is U ~ W^4 if the cell size is smaller than a critical value.Comment: 14 pages, 20 figures, revtex4, submitted to Combustion Theory and Modellin

Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

Advantages and diagnostic effectiveness of the two most widely used resequencing approaches, whole exome (WES) and whole genome (WGS) sequencing, are often debated. WES dominated large-scale resequencing projects because of lower cost and easier data storage and processing. Rapid development of 3(rd) generation sequencing methods and novel exome sequencing kits predicate the need for a robust statistical framework allowing informative and easy performance comparison of the emerging methods. In our study we developed a set of statistical tools to systematically assess coverage of coding regions provided by several modern WES platforms, as well as PCR-free WGS. We identified a substantial problem in most previously published comparisons which did not account for mappability limitations of short reads. Using regression analysis and simple machine learning, as well as several novel metrics of coverage evenness, we analyzed the contribution from the major determinants of CDS coverage. Contrary to a common view, most of the observed bias in modern WES stems from mappability limitations of short reads and exome probe design rather than sequence composition. We also identified the similar to 500kb region of human exome that could not be effectively characterized using short read technology and should receive special attention during variant analysis. Using our novel metrics of sequencing coverage, we identified main determinants of WES and WGS performance. Overall, our study points out avenues for improvement of enrichment-based methods and development of novel approaches that would maximize variant discovery at optimal cost

Coulomb dissociation of O-16 into He-4 and C-12

We measured the Coulomb dissociation of O-16 into He-4 and C-12 within the FAIR Phase-0 program at GSI Helmholtzzentrum fur Schwerionenforschung Darmstadt, Germany. From this we will extract the photon dissociation cross section O-16(alpha,gamma)C-12, which is the time reversed reaction to C-12(alpha,gamma)O-16. With this indirect method, we aim to improve on the accuracy of the experimental data at lower energies than measured so far. The expected low cross section for the Coulomb dissociation reaction and close magnetic rigidity of beam and fragments demand a high precision measurement. Hence, new detector systems were built and radical changes to the (RB)-B-3 setup were necessary to cope with the high-intensity O-16 beam. All tracking detectors were designed to let the unreacted O-16 ions pass, while detecting the C-12 and He-4

Centrality evolution of the charged-particle pseudorapidity density over a broad pseudorapidity range in Pb-Pb collisions at root s(NN)=2.76TeV

Peer reviewe

Superconducting Sub-Terahertz Oscillator with Continuous Frequency Tuning

The development and approbation of a superconducting local oscillator based on a long Josephson junction made it possible to create a fully superconducting integrated receiver in sub-terahertz frequency range, which was successfully tested both on board a high-altitude balloon and in the laboratory. In order to expand the frequency range of a superconducting integrated local oscillator, it is necessary to ensure the continuous tuning of its frequency at an arbitrary bias current, including a so-called resonant mode regime. The resonant mode regime takes place for high-quality tunnel junctions with low leakage; in this regime, stable generation is possible only at Fiske steps, the distance in frequency between which is tens of GHz. A method for suppressing resonances has been proposed and implemented; this method is based on the introduction of normal metal layers into the region near the long Josephson junction. Modeling of the propagation of electromagnetic waves in the proposed integrated structure was carried out; experimental samples were fabricated, and their comprehensive study was performed. The complete suppression of resonances and the possibility of the continuous tuning of the frequency of a superconducting local oscillator in the range of 200–700 GHz have been demonstrated. The linewidth of the FFO radiation does not exceed 15 MHz over the entire frequency range, which makes it possible to implement the phase locked loop mode in an integrated receiver intended for spectral studies

Superconducting integrated submillimeter receiver for TELIS

In this report an overview of the results on the development of a single-chip superconducting integrated receiver for the Terahertz Limb Sounder (TELIS) balloon project intended to measure a variety of stratosphere trace gases is presented. The Superconducting Integrated Receiver (SIR) comprises in one chip a planar antenna integrated with a superconductor-insulator-superconductor (SIS) mixer, a superconducting Flux Flow Oscillator (FFO) acting as Local Oscillator (LO) and a second SIS harmonic mixer (HM) for FFO phase locking. As a result of the FFO design optimization a free-running linewidth between 9 and 1.5 MHz has been measured in the frequency range 500-710 GHz resulting in phase-locking of 35 to 95% of the FFO power correspondingly. A new generation of the SIR devices with improved FFO performance and optimized interface between FFO and SIS/HM has been developed and comprehensively tested. As a result all required TELIS parameters were demonstrated., Phase-locked FFO operation over entire SIR channel frequency range has been realized, spectral resolution below 1 MHz has been confirmed by gas cell and CW signal measurements. An uncorrected double side band (DSB) noise temperature below 250 K has been measured with the phase-locked FFO. The intermediate frequency bandwidth 4-8 GHz; has been realized. To ensure remote operation of the phase-locked SIR several procedures for its automatic computer control have been developed and tested