Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

Cardioprotection and lifespan extension by the natural polyamine spermidine

Aging is associated with an increased risk of cardiovascular disease and death. Here we show that oral supplementation of the natural polyamine spermidine extends the lifespan of mice and exerts cardioprotective effects, reducing cardiac hypertrophy and preserving diastolic function in old mice. Spermidine feeding enhanced cardiac autophagy, mitophagy and mitochondrial respiration, and it also improved the mechano-elastical properties of cardiomyocytes in vivo, coinciding with increased titin phosphorylation and suppressed subclinical inflammation. Spermidine feeding failed to provide cardioprotection in mice that lack the autophagy-related protein Atg5 in cardiomyocytes. In Dahl salt-sensitive rats that were fed a high-salt diet, a model for hypertension-induced congestive heart failure, spermidine feeding reduced systemic blood pressure, increased titin phosphorylation and prevented cardiac hypertrophy and a decline in diastolic function, thus delaying the progression to heart failure. In humans, high levels of dietary spermidine, as assessed from food questionnaires, correlated with reduced blood pressure and a lower incidence of cardiovascular disease. Our results suggest a new and feasible strategy for protection against cardiovascular disease

Die Lehre von der Gemeinschaft der Heiligen im christl. Altertum : eine dogmengeschichtliche Studie

von J. P. Kirsc

Die Finanzverwaltung des Kardinalkollegiums im XIII. und XIV. Jahrhundert

von Joh. Peter Kirsc

Joseph Kardinal Hergenröther's Handbuch der allgemeinen Kirchengeschichte.

Includes bibliographical references and indexes."Quellen und Hilfsmittel der Kirchengeschichte" ; v. 1, p. 6-17.Bd. 1: Die Kirche in der antiken Kulturwelt. -- 1902 -- Bd. 2: Die Kirche als Leiterin der abendländischen Gesellschaft. -- 1904 -- 3. Schluss-Bd: Die Kirche nach dem Zusammenbruch der religiösen Einheit im Abendland und die Ausbreitung des Christentums in den aussereuropäischen Weltteilen. -- 1907-1909 -- Abt. 1: Vom Anfang des 16. bis zur Mitte des 17. Jahrhunderts. -- 1907 -- 2. Schluss-Abt.: Von der Mitte des 17. Jahrhunderts bis zur Neuzeit. -- 1909.Mode of access: Internet

Forschungen zur christlichen Literatur- und Dogmengeschichte.

Editors: A. Ehrhard, J.P. Kirsch.Imprint varies: Paderborn : F. Schöningh, .Mode of access: Internet

Anderson Localization for Random Schrödinger Operators with Long Range Interactions

We prove pure point spectrum with exponentially decaying eigenfunctions at all band edges for Schrodinger Operators with a periodic potential plus a random potential of the form V ! (x) = P q i (!)f(x \Gamma i) where f decays at infinity like jxj \Gammam for m ? 4d resp. m ? 3d depending on the regularity of f . The random variables q i are supposed to be independent and identically distributed. We assume that their distribution has a bounded density of compact support. AMS Classification: 81Q10 (35J10,47A10) Keywords: Random Operators, Localization, Long Range Potentials, Schrodinger Operators Research supported by NSF-Grants DMS-9401417 and DMS-9706076 1 Introduction At least since the groundbreaking work of Lifshitz in the early 60s it is widely accepted among physicists that random models of solid state physics should exhibit pure point spectrum near fluctuation boundaries. The latter are those parts of the spectrum which are determined by rather rare events. To present..

The burden of conscientiousness? Examining brain activation and cortisol response during social evaluative stress

Although conscientiousness has for a long time been considered generally adaptive, there are findings challenging this view, suggesting that conscientiousness might be less advantageous during uncontrollable stress. We here examined the impact of conscientiousness on brain activation during and the cortisol response following an uncontrollable social evaluative stress task in order to test this hypothesis. Brain activation and cortisol levels were measured during an fMRI stress task, where subjects (n=86) performed cognitive tasks containing preprogrammed failure under time pressure, while being monitored by a panel of experts inducing social-evaluative threat. The degree of conscientiousness was measured using the NEO-FFI. We observed a positive correlation between conscientiousness and salivary cortisol levels in response to the stressful task in male subjects only. In male subjects conscientiousness correlated positively with activation in right amygdala and left insula, and, moreover, mediated the influence of amygdala and insula activation on cortisol output. This pattern of brain activation can be interpreted as a disadvantageous response to uncontrollable stress to which highly conscientious individuals might be predisposed. This is the first study showing the effect of conscientiousness on physiology and brain activation to an uncontrollable psychosocial stressor. Our results provide neurobiological evidence for the hypothesis that conscientiousness should not just be seen as beneficial, but rather as a trait associated with either costs or benefits depending on the extent to which one is in control of the situation. (C) 2017 Elsevier Ltd. All rights reserved