37 research outputs found

    A template for resource productivity/sustainability programs in forest products manufacturing facilities

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    53 p.This document introduces the principles and practices of resource productivity and sustainable development as they may apply to forest products manufacturing firms and facilities. It was developed by a group of forest products professionals with staffing assistance from the Center for Watershed and Community Health at Portland State University. This is a working draft, and the authors request feedback on content, presentation and usefulness. Part I of the document provides background information on resource productivity and sustainability. It is intended to prepare the reader to use the template outlined in Part II. The template is organized around the steps involved with answering the five key questions that should drive the development of your resource productivity/sustainability program

    Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser

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    Citation: Ekeberg, T., Svenda, M., Abergel, C., Maia, F., Seltzer, V., Claverie, J. M., . . . Hajdu, J. (2015). Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser. Physical Review Letters, 114(9), 6. doi:10.1103/PhysRevLett.114.098102We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.Additional Authors: Andersson, I.;Loh, N. D.;Martin, A. V.;Chapman, H.;Bostedt, C.;Bozek, J. D.;Ferguson, K. R.;Krzywinski, J.;Epp, S. W.;Rolles, D.;Rudenko, A.;Hartmann, R.;Kimmel, N.;Hajdu, J

    Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials

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    An amendment to this paper has been published and can be accessed via the original article

    Patient and stakeholder engagement learnings: PREP-IT as a case study

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    Anthropogener und klimatischer Einfluss auf die N_2O und CH_4-Fluesse zwischen Boden und Atmosphaere. Regulation der Methanemission aus Feuchtgebieten Abschlussbericht 2001

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    Predicting climatic changes is only possible, if the variation in source strengths of greenhouse gases can be predicted, too. Hence, the development of process-based models is necessary. The same type of models is needed for analysis of past climate changes. We have focused on methane, its turnover, and its emission from wetlands. In this study we have measured a set of data that allows validation of process-based methane models. The set contains both biotic and abiotic data as well as measurements of production, consumption, emission, and isotopic signatures of methane in a northern raised bog. We have analyzed the implementation of these processes in a recently published model and give recommendations for a further improvement based on ecology and biogeochemistry of wetlands. (orig.)SIGLEAvailable from TIB Hannover: F02B1429 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung und Forschung, Berlin (Germany)DEGerman

    Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart

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    Myocardial dysfunction is commonly associated with accumulation of cardiac lipid droplets (LDs). Perilipin 2 (Plin2) is a LD protein that is involved in LD formation, stability and trafficking events within the cell. Even though Plin2 is highly expressed in the heart, little is known about its role in myocardial lipid storage. A recent report shows that cardiac overexpression of Plin2 result in massive myocardial steatosis suggesting that Plin2 stabilizes LDs. In this study, we hypothesized that deficiency in Plin2 would result in reduced myocardial lipid storage. In contrast to our hypothesis, we found increased accumulation of triglycerides in hearts, and specifically in cardiomyocytes, from Plin2−/− mice. Although Plin2−/− mice had markedly enhanced lipid levels in the heart, they had normal heart function under baseline conditions and under mild stress. However, after an induced myocardial infarction, stroke volume and cardiac output were reduced in Plin2−/− mice compared with Plin2+/+ mice. We further demonstrated that the increased triglyceride accumulation in Plin2-deficient hearts was caused by altered lipophagy. Together, our data show that Plin2 is important for proper hydrolysis of LDs
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