781 research outputs found

    Employability of the Graduates From 14 CFR PART 147 Schools: Understanding the Critical Factors Using Covariance-Based SEM

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    Certified aviation mechanics are crucial to maintaining a healthy aviation industry in the United States. To fulfill this need, 14 CFR Part 147 aviation mechanic schools educate students under the supervision of the FAA. Though the demand for mechanics is projected to increase over the next 20 years, the supply is not expected to meet this demand. Therefore, the research discussed in this paper addressed this potential deficiency by asking two research questions. The first related to the factors students feel affect their employability, and the second was used to analyze whether the students learned these skills at school or through personal development. To address the research questions, a Q-sort was conducted with recruiters in the industry. The recruiters organized 19 factors, which the researcher chose during the literature review, in order of importance to the industry. The 11 factors that rated the highest were then placed in a survey. Questions for each factor were chosen from published scales and combined into a survey that was administered in person and online. After data cleansing, 210 records were used in the model. The first step of the analysis was to complete a confirmatory factor analysis in AMOS. The factors used in the model for the first question were the top four from the Q-sort results: technical skills, problem solving, reliability, and teamwork. The model fit was excellent, with a CFI of .977, TLI equal to .969, and RMSEA of .041. The covariance-based structural equation model (SEM) was then executed. Among all participants, none of the factors had a significant impact on self-perceived employability. However, after separating the data between participants who were employed and unemployed, the model was adjusted and the model fit maintained excellence. The new SEM analysis showed employed graduates felt problem solving significantly affected their employability. In contrast, unemployed students felt reliability significantly affected their employability. For the second research question, the SEM analysis for combined employed and unemployed participants showed the critical skills for employability were being taught in 14 CFR Part 147 schools after model fit statistics of .918 CFI, .907 TLI, and RMSEA of .067 were found in the CFA. Once the data were separated into unemployed and employed participants, the employed group measured a significant and positive effect on the employability-critical skills being taught in the mechanic schools, whereas the unemployed participants did not. All three groups resulted in a nonsignificant effect of personally developed skills. These results are critical for industry leaders to understand and incorporate into the education of aviation mechanics. Employability studies have been conducted in the business field for decades to understand and return the unemployed to employment. In the realm of education, results can help school leaders teach their students which factors are critical to employers and ensure these skills are highlighted in the curriculum. Within the aviation industry, this information can be used to address the growing gap between the supply and demand of qualified mechanics. If actions are not taken over the next few years, adverse effects, such as canceled flights, delayed deliveries, and increased costs will be felt throughout the industry

    Evaluation of COVID-19 on AMT Part 147 Schools Related to Knowledge-based Testing Scores for AMG, AMA, & AMP Mechanic Certification Examinations

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    The FAA mandates under CFR 14, Part 65 Subpart D § 65.75 Knowledge requirements, that an applicant for a mechanics certificate must possess. The knowledge-based test, more commonly referred to as the “written” examinations and covers materials specific to either an airframe certificate (AMA) or a powerplant certificate (AMP) with the general (AMG) component being common to each. The prescribed level of testing for a Part 147 school is specifically outlined under § 147.38a Quality of instruction and measured by the results of the KBT examinations for all students tested and measured against a national norm. During the period of COVID both training and learning challenges have taken place throughout the system of approved institutions. This paper investigates standardized national norm scores at a pre-pandemic level and compares them to the time frame of the results during the actual pandemic using data from March 2020 up to the current period. Data gathered from the FAA Form 8080-08 collected by AFS630 was reviewed and analyzed and stratified by institution, regions, and students. A noticeable drop in the national scores and the individual scores related to each of the three testing regimes, AMG, AMA, and AMP of all the accredited schools was documented. This research endeavors to draw possible conclusions as to the underlying fundamental reasons for the phenomena as discussed, offering both insight and possible corrective actions to be considered

    Shallow stratigraphic control on pockmark distribution in north temperate estuaries

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    This paper is not subject to U.S. copyright. The definitive version was published in Marine Geology 329-331 (2012): 34-45, doi:10.1016/j.margeo.2012.09.006.Pockmark fields occur throughout northern North American temperate estuaries despite the absence of extensive thermogenic hydrocarbon deposits typically associated with pockmarks. In such settings, the origins of the gas and triggering mechanism(s) responsible for pockmark formation are not obvious. Nor is it known why pockmarks proliferate in this region but do not occur south of the glacial terminus in eastern North America. This paper tests two hypotheses addressing these knowledge gaps: 1) the region's unique sea-level history provided a terrestrial deposit that sourced the gas responsible for pockmark formation; and 2) the region's physiography controls pockmarks distribution. This study integrates over 2500 km of high-resolution swath bathymetry, Chirp seismic reflection profiles and vibracore data acquired in three estuarine pockmark fields in the Gulf of Maine and Bay of Fundy. Vibracores sampled a hydric paleosol lacking the organic-rich upper horizons, indicating that an organic-rich terrestrial deposit was eroded prior to pockmark formation. This observation suggests that the gas, which is presumably responsible for the formation of the pockmarks, originated in Holocene estuarine sediments (loss on ignition 3.5–10%), not terrestrial deposits that were subsequently drowned and buried by mud. The 7470 pockmarks identified in this study are non-randomly clustered. Pockmark size and distribution relate to Holocene sediment thickness (r2 = 0.60), basin morphology and glacial deposits. The irregular underlying topography that dictates Holocene sediment thickness may ultimately play a more important role in temperate estuarine pockmark distribution than drowned terrestrial deposits. These results give insight into the conditions necessary for pockmark formation in nearshore coastal environments.Graduate support for Brothers came from a Maine Economic Improvement Fund Dissertation Fellowship

    Better supporting workers in ML workplaces

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    This workshop is aimed at bringing together a multidisciplinary group to discuss Machine Learning and its application in the workplace as a practical, everyday work matter. It's our hope this is a step toward helping us design better technology and user experiences to support the accomplishment of that work, while paying attention to workplace context. Despite advancement and investment in Machine Learning (ML) business applications, understanding workers in these work contexts have received little attention. As this category experiences dramatic growth, it's important to better understand the role that workers play, both individually and collaboratively, in a workplace where the output of prediction and machine learning is becoming pervasive. There is a closing window of opportunity to investigate this topic as it proceeds toward ubiquity. CSCW and HCI offer concepts, tools and methodologies to better understand and build for this future

    Building a diverse workforce and thinkforce to reduce health disparities

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    The Research Centers in Minority Institutions (RCMI) Program was congressionally man-dated in 1985 to build research capacity at institutions that currently and historically recruit, train, and award doctorate degrees in the health professions and health-related sciences, primarily to individuals from underrepresented and minority populations. RCMI grantees share similar infrastructure needs and institutional goals. Of particular importance is the professional development of multidisciplinary teams of academic and community scholars (the “workforce”) and the harnessing of the heterogeneity of thought (the “thinkforce”) to reduce health disparities. The purpose of this report is to summarize the presentations and discussion at the RCMI Investigator Development Core (IDC) Workshop, held in conjunction with the RCMI Program National Conference in Bethesda, Maryland, in December 2019. The RCMI IDC Directors provided information about their professional development activities and Pilot Projects Programs and discussed barriers identified by new and early-stage investigators that limit effective career development, as well as potential solutions to overcome such obstacles. This report also proposes potential alignments of professional development activities, targeted goals and common metrics to track productivity and success

    Genomic Responses to Abnormal Gene Dosage: The X Chromosome Improved on a Common Strategy

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    This new primer, which discusses a study by Zhang et al., provides an overview of the process by which chromosomes achieve dose compensation and the mechanisms underlying this phenomenon in Drosophila S2 cells

    A Phase I Double Blind, Placebo-Controlled, Randomized Study of a Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected Adults

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    <div><h3>Background</h3><p>We conducted a phase I, randomized, double-blind, placebo-controlled trial to assess the safety and immunogenicity of escalating doses of two recombinant replication defective adenovirus serotype 35 (Ad35) vectors containing gag, reverse transcriptase, integrase and nef (Ad35-GRIN) and env (Ad35-ENV), both derived from HIV-1 subtype A isolates. The trial enrolled 56 healthy HIV-uninfected adults.</p> <h3>Methods</h3><p>Ad35-GRIN/ENV (Ad35-GRIN and Ad35-ENV mixed in the same vial in equal proportions) or Ad35-GRIN was administered intramuscularly at 0 and 6 months. Participants were randomized to receive either vaccine or placebo (10/4 per group, respectively) within one of four dosage groups: Ad35-GRIN/ENV 2×10<sup>9</sup> (A), 2×10<sup>10</sup> (B), 2×10<sup>11</sup> (C), or Ad35-GRIN 1×10<sup>10</sup> (D) viral particles.</p> <h3>Results</h3><p>No vaccine-related serious adverse event was reported. Reactogenicity events reported were dose-dependent, mostly mild or moderate, some severe in Group C volunteers, all transient and resolving spontaneously. IFN-γ ELISPOT responses to any vaccine antigen were detected in 50, 56, 70 and 90% after the first vaccination, and in 75, 100, 88 and 86% of Groups A–D vaccine recipients after the second vaccination, respectively. The median spot forming cells (SFC) per 10<sup>6</sup> PBMC to any antigen was 78–139 across Groups A–C and 158–174 in Group D, after each of the vaccinations with a maximum of 2991 SFC. Four to five HIV proteins were commonly recognized across all the groups and over multiple timepoints. CD4+ and CD8+ T-cell responses were polyfunctional. Env antibodies were detected in all Group A–C vaccinees and Gag antibodies in most vaccinees after the second immunization. Ad35 neutralizing titers remained low after the second vaccination.</p> <h3>Conclusion/Significance</h3><p>Ad35-GRIN/ENV reactogenicity was dose-related. HIV-specific cellular and humoral responses were seen in the majority of volunteers immunized with Ad35-GRIN/ENV or Ad35-GRIN and increased after the second vaccination. T-cell responses were broad and polyfunctional.</p> <h3>Trial Registration</h3><p>ClinicalTrials.gov <a href="http://clinicaltrials.gov/ct2/results?term=NCT00851383">NCT00851383</a></p> </div

    Genome3D: exploiting structure to help users understand their sequences.

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    Genome3D (http://www.genome3d.eu) is a collaborative resource that provides predicted domain annotations and structural models for key sequences. Since introducing Genome3D in a previous NAR paper, we have substantially extended and improved the resource. We have annotated representatives from Pfam families to improve coverage of diverse sequences and added a fast sequence search to the website to allow users to find Genome3D-annotated sequences similar to their own. We have improved and extended the Genome3D data, enlarging the source data set from three model organisms to 10, and adding VIVACE, a resource new to Genome3D. We have analysed and updated Genome3D's SCOP/CATH mapping. Finally, we have improved the superposition tools, which now give users a more powerful interface for investigating similarities and differences between structural models

    De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

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    Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic regulator SMCHD1 mapping to the extended ATPase domain of the encoded protein cause BAMS in all 14 cases studied. All mutations were de novo where parental DNA was available. Biochemical tests and in vivo assays in Xenopus laevis embryos suggest that these mutations may behave as gain-of-function alleles. This finding is in contrast to the loss-of-function mutations in SMCHD1 that have been associated with facioscapulohumeral muscular dystrophy (FSHD) type 2. Our results establish SMCHD1 as a key player in nasal development and provide biochemical insight into its enzymatic function that may be exploited for development of therapeutics for FSHD

    The genomes of two key bumblebee species with primitive eusocial organization

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    Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. Bumblebees are also invaluable natural and agricultural pollinators, and there is widespread concern over recent population declines in some species. High-quality genomic data will inform key aspects of bumblebee biology, including susceptibility to implicated population viability threats. Results: We report the high quality draft genome sequences of Bombus terrestris and Bombus impatiens, two ecologically dominant bumblebees and widely utilized study species. Comparing these new genomes to those of the highly eusocial honeybee Apis mellifera and other Hymenoptera, we identify deeply conserved similarities, as well as novelties key to the biology of these organisms. Some honeybee genome features thought to underpin advanced eusociality are also present in bumblebees, indicating an earlier evolution in the bee lineage. Xenobiotic detoxification and immune genes are similarly depauperate in bumblebees and honeybees, and multiple categories of genes linked to social organization, including development and behavior, show high conservation. Key differences identified include a bias in bumblebee chemoreception towards gustation from olfaction, and striking differences in microRNAs, potentially responsible for gene regulation underlying social and other traits. Conclusions: These two bumblebee genomes provide a foundation for post-genomic research on these key pollinators and insect societies. Overall, gene repertoires suggest that the route to advanced eusociality in bees was mediated by many small changes in many genes and processes, and not by notable expansion or depauperation
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