Web based hybrid volumetric visualisation of urban GIS data: Integration of 4D Temperature and Wind Fields with LoD-2 CityGML models

City models visualisation, buildings, structures and volumetric information, is an important task in Computer Graphics and Urban Planning -- The different formats and data sources involved in the visualisation make the development of applications a big challenge -- We present a homogeneous web visualisation framework using X3DOM and MEDX3DOM for the visualisation of these urban objects -- We present an integration of different declarative data sources, enabling the utilization of advanced visualisation algorithms to render the models -- It has been tested with a city model composed of buildings from the Madrid University Campus, some volumetric datasets coming from Air Quality Models and 2D layers wind datasets -- Results show that the visualisation of all the urban models can be performed in real time on the Web -- An HTML5 web interface is presented to the users, enabling real time modifications of visualisation parameter

Safe electrode trajectory planning in SEEG via MIP-based vessel segmentation

Stereo-ElectroEncephaloGraphy (SEEG) is a surgical procedure that allows brain exploration of patients affected by focal epilepsy by placing intra-cerebral multi-lead electrodes. The electrode trajectory planning is challenging and time consuming. Various constraints have to be taken into account simultaneously, such as absence of vessels at the electrode Entry Point (EP), where bleeding is more likely to occur. In this paper, we propose a novel framework to help clinicians in defining a safe trajectory and focus our attention on EP. For each electrode, a Maximum Intensity Projection (MIP) image was obtained from Computer Tomography Angiography (CTA) slices of the brain first centimeter measured along the electrode trajectory. A Gaussian Mixture Model (GMM), modified to include neighborhood prior through Markov Random Fields (GMM-MRF), is used to robustly segment vessels and deal with the noisy nature of MIP images. Results are compared with simple GMM and manual global Thresholding (Th) by computing sensitivity, specificity, accuracy and Dice similarity index against manual segmentation performed under the supervision of an expert surgeon. In this work we present a novel framework which can be easily integrated into manual and automatic planner to help surgeon during the planning phase. GMM-MRF qualitatively showed better performance over GMM in reproducing the connected nature of brain vessels also in presence of noise and image intensity drops typical of MIP images. With respect Th, it is a completely automatic method and it is not inuenced by inter-subject variability

Nearly complete genome sequences of eight rabies virus strains obtained from domestic carnivores in the Democratic Republic of the Congo

In this report, we describe eight nearly complete genome sequences of rabies virus strains collected in the Democratic Republic of the Congo from domestic carnivores in 2017 and 2018. All of them clustered into a specific phylogroup among the Africa 1b lineage in the Cosmopolitan clade

Toxoplasmosis prevalence in cats of Kingabwa and Limete résidentiel districts in Kinshasa

Durant sept mois, 150 échantillons de selles ont été collectés chez les chats des quartiers Kingabwa et Limete résidentiel à Kinshasa. Les analyses coprologiques par flottaison quantitative ont donné une prévalence brute de toxoplasmose de 14,7 %, à raison de 20 % à Kingabwa et de 8,6 % à Limete résidentiel pour ce qui est des quartiers (p? 0,05), de 13,3 % chez les mâles et de 16 % chez les femelles (p?0,05) concernant le sexe et de 16 % chez les chats âgés d’une année et plus et de 13,3 % chez ceux ayant moins d’une année (p?0,05) pour ce qui est de l’âge. Les chats joueraient un rôle important dans la forte prévalence de la toxoplasmose humaine observée à Kinshasa. Les médecins vétérinaires devront intégrer en plus du vermifugeage, l’administration de la pyriméthamine et de la sulfadiazine lors de la vaccination antirabique chez les chats afin de lutter contre la toxoplasmose féline. Mots-clés: Prévalence, Toxoplasmose, chats, Kingabwa, Limete résidentiel, Kinshasa.During seven months, 150 fecal samples were collected in cats of Kingabwa and residential Limete in Kinshasa. Coprological analysis by quantitative flotation gave a crude prevalence of 14.5 %, with 20 % prevalence at Kingabwa and 8.6 % for residential Limete in terms of neighborhoods (p?0.05), 13.3 % for males and 16 % for females (p?0,05) and 16 % of cats aged one year or more and 13.3 % in those with less than a year (p?0,05). Cats play an important role in the high prevalence of human toxoplasmosis observed in Kinshasa. Veterinarians should integrate, in addition to deworming, the administration of pyriméthamine and sulfadiazine at the time of anti-rabies vaccination of cats in order to fight against feline toxoplasmosis. Keywords: Prevalence, Toxoplasmosis, cats, Kingabwa, Limete residential, Kinshasa

Toxoplasmosis prevalence in cats of Kingabwa and Limete résidentiel districts in Kinshasa

During seven months, 150 fecal samples were collected in cats of Kingabwa and residential Limete in Kinshasa. Coprological analysis by quantitative flotation gave a crude prevalence of 14.5 %, with 20 % prevalence at Kingabwa and 8.6 % for residential Limete in terms of neighborhoods (p<0.05), 13.3 % for males and 16 % for females (p<0,05) and 16 % of cats aged one year or more and 13.3 % in those with less than a year (p<0,05). Cats play an important role in the high prevalence of human toxoplasmosis observed in Kinshasa. Veterinarians should integrate, in addition to deworming, the administration of pyriméthamine and sulfadiazine at the time of anti-rabies vaccination of cats in order to fight against feline toxoplasmosis

The Ability to Look: Management of Breast Disease in the Democratic Republic of the Congo Using Smart Ultrasound Technology

Background: The vast majority of women with breast cancer in sub-Saharan Africa present with advanced stage disease, due primarily to the lack of opportunities for early detection and treatment. As part of a larger effort to increase access to diagnostic and therapeutic services for women's cancers in the Democratic Republic of Congo (DRC), we implemented a curriculum to train the local workforce and a program to build the supportive infrastructure for the diagnosis and treatment of breast cancer at a private sector health facility (Biamba Marie Mutombo Hospital) in Kinshasa. Study design: After onsite trainings in the DRC by a US breast surgeon (RT), Congolese surgeons, general physicians, physician assistants, and nurses used the Phillips Lumify smart-phone ultrasound device to perform and interpret the results of whole breast ultrasound on symptomatic women. Surgeons were trained to perform ultrasound-guided core needle biopsy on those who met the criteria for tissue diagnosis, after which they trained nurses to do the same. Results: Over 3 years, 5,211 patients were identified as having a breast abnormality on clinical breast examination. Ultrasound abnormalities were noted in 1,493 (27%) patients, of which 632 (42%) met the criteria for ultrasound-guided core needle biopsy or fine needle aspiration. Pathology reports were available on 368 (58%) patients who underwent biopsy, of which 164 were malignant and 204 benign. Conclusions: We demonstrated how the “ability to look” using smart technology can be successfully used to augment clinical breast exam and triage patients for biopsy in a resource-constrained African setting

Seroepidemiology of Bovine Viral Diarrhoea Virus (BVDV) in the Adamawa Region of Cameroon and Use of the SPOT Test to Identify Herds with PI Calves

Bovine viral diarrhoea, caused by the bovine viral diarrhoea virus (BVDV) in the Pestivirus genus of the Flaviviridae, is one of the most important diseases of cattle world wide causing poor reproductive performance in adult cattle and mucosal disease in calves. In addition it causes immunosuppression and increased susceptibility to other infections, the impact of which is uncertain, particularly in sub-Saharan Africa where animals are exposed to a much wider range and higher intensity of infections compared to Europe. There are no previous estimates of the seroprevalence of BVDV in cattle in Cameroon. This paper describes the serological screening for antibodies to BVDV and antigen of BVDV in a cattle population in the Adamawa Region of Cameroon in 2000. The estimates of herd-level and within herd seroprevalences adjusted for test imperfections were 92% and 30% respectively and 16.5% of herds were classed as having a persistently infected calf (PI) in the herd within the last year based on the “spot” test approach. There was evidence of clustering of herds with PI calves across the north and west of the Region which corresponds with the higher cattle density areas and of self-clearance of infection from herds. A multivariable model was developed for the risk of having a PI calf in the herd; proximity to antelope, owning a goat, mixing with 10 other herds at grazing and the catchment area of the veterinary centre the herd was registered at were all significant risk factors. Very little is known about BVDV in sub-Saharan Africa and these high seroprevalences suggest that there is a large problem which may be having both direct impacts on fertility and neonate mortality and morbidity and also indirect effects through immunosuppression and susceptibility to other infections. Understanding and accounting for BVDV should be an important component of epidemiological studies of other diseases in sub-Saharan Africa

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Business model innovation for eco-efficiency: an empirical study

Business model has the potential to create value and capture value for companies, which is critical for their sustainable development [1]. The concept of eco-efficiency can be a useful concept to link an enterprise’s business with sustainable development as well as achieving long-term profits [2,3]. Extant lit- erature reveals that there is a need to study business model innovation and eco- efficiency under one text to achieve a win-win rationale to increase profits while reducing environmental impact [4,5]. This empirical study conducted 8-in-depth case studies with manufacturing companies across UK and China. The author synthesized the cases and concluded the measures of business model innovation for eco-efficiency in five categories, namely (1) Selling of service model, (2) Direct selling model, (3) Collaboration strategy, (4) Whole system design strat- egy, and (5) Technology renovation strategy. The empirical finding suggests the adaptation of strategy and exploitation of the technologies are essential to busi- ness model innovation when manufacturing companies seeking to implement eco-efficiency