Factores que conducen a la delincuencia juvenil en los expedientes tramitados en los Juzgados Especializados de Familia de Tarapoto - 2018

La delincuencia juvenil es un problema social presente en todo el mundo en magnitudes diversas y la Región San Martín no es la excepción. La investigación tuvo como objetivo identificar los factores que conducen a la delincuencia juvenil en los expedientes tramitados en los Juzgados especializados de Familia de Tarapoto – 2018, la muestra fue 30 expedientes revisados, 2 jueces entrevistados y 31 menores sancionados encuestados. Los resultados demostraron que: El 47% de los expedientes tenían como causal de delito el robo agravado involucrando al 58% de los menores sancionado, a este delito están asociados el factor familiar con 91% de menores con problemas familiares, el factor personal con 48%, el factor socioeconómico y social con 43% y el factor educativo con 30%; para el caso de los delitos contra la libertad sexual y lesiones culposas el factor personal influye con el 75%, el factor familiar y social influye con el 50% y el factor educativo con el 25%. El 100% de los jueces entrevistados mencionan que los factores más influyentes en la delincuencia juvenil son el factor familiar y el factor socioeconómico y el 50% de jueces consideran que también influyen los factores personales y sociales. La encuesta de respuestas múltiples demostró que el 84% los encuestados consideran que el factor socioeconómico “siempre” influye en la delincuencia juvenil, el 61% considera que “siempre” influye el factor familiar, el 52% cree que “siempre” influye el factor institucional, 45% afirma que “siempre” influye el factor educativo, el 68% y el 36% consideran que “casi siempre” influyen los factores social y político y el 74% considera que a veces influye el factor personal

Zero-free regions for multivariate Tutte polynomials (alias Potts-model partition functions) of graphs and matroids

The chromatic polynomial P_G(q) of a loopless graph G is known to be nonzero (with explicitly known sign) on the intervals (-\infty,0), (0,1) and (1,32/27]. Analogous theorems hold for the flow polynomial of bridgeless graphs and for the characteristic polynomial of loopless matroids. Here we exhibit all these results as special cases of more general theorems on real zero-free regions of the multivariate Tutte polynomial Z_G(q,v). The proofs are quite simple, and employ deletion-contraction together with parallel and series reduction. In particular, they shed light on the origin of the curious number 32/27.Comment: LaTeX2e, 49 pages, includes 5 Postscript figure

Lagrangian Description of the Variational Equations

A variant of the usual Lagrangian scheme is developed which describes both the equations of motion and the variational equations of a system. The required (prolonged) Lagrangian is defined in an extended configuration space comprising both the original configurations of the system and all the virtual displacements joining any two integral curves. Our main result establishes that both the Euler-Lagrange equations and the corresponding variational equations of the original system can be viewed as the Lagrangian vector field associated with the first prolongation of the original LagrangianAfter discussing certain features of the formulation, we introduce the so-called inherited constants of the motion and relate them to the Noether constants of the extended system

Is the five-flow conjecture almost false?

The number of nowhere zero Z_Q flows on a graph G can be shown to be a polynomial in Q, defining the flow polynomial \Phi_G(Q). According to Tutte's five-flow conjecture, \Phi_G(5) > 0 for any bridgeless G.A conjecture by Welsh that \Phi_G(Q) has no real roots for Q \in (4,\infty) was recently disproved by Haggard, Pearce and Royle. These authors conjectured the absence of roots for Q \in [5,\infty). We study the real roots of \Phi_G(Q) for a family of non-planar cubic graphs known as generalised Petersen graphs G(m,k). We show that the modified conjecture on real flow roots is also false, by exhibiting infinitely many real flow roots Q>5 within the class G(nk,k). In particular, we compute explicitly the flow polynomial of G(119,7), showing that it has real roots at Q\approx 5.0000197675 and Q\approx 5.1653424423. We moreover prove that the graph families G(6n,6) and G(7n,7) possess real flow roots that accumulate at Q=5 as n\to\infty (in the latter case from above and below); and that Q_c(7)\approx 5.2352605291 is an accumulation point of real zeros of the flow polynomials for G(7n,7) as n\to\infty.Comment: 44 pages (LaTeX2e). Includes tex file, three sty files, and a mathematica script polyG119_7.m. Many improvements from version 3, in particular Sections 3 and 4 have been mostly re-writen, and Sections 7 and 8 have been eliminated. (This material can now be found in arXiv:1303.5210.) Final version published in J. Combin. Theory

Electric-magnetic duality and renormalization in curved spacetimes

We point out that the duality symmetry of free electromagnetism does not hold in the quantum theory if an arbitrary classical gravitational background is present. The symmetry breaks in the process of renormalization, as also happens with conformal invariance. We show that a similar duality anomaly appears for a massless scalar field in 1 + 1 dimensions

Ground State Entropy of the Potts Antiferromagnet on Strips of the Square Lattice

We present exact solutions for the zero-temperature partition function (chromatic polynomial $P$) and the ground state degeneracy per site $W$ (= exponent of the ground-state entropy) for the $q$-state Potts antiferromagnet on strips of the square lattice of width $L_y$ vertices and arbitrarily great length $L_x$ vertices. The specific solutions are for (a) $L_y=4$, $(FBC_y,PBC_x)$ (cyclic); (b) $L_y=4$, $(FBC_y,TPBC_x)$ (M\"obius); (c) $L_y=5,6$, $(PBC_y,FBC_x)$ (cylindrical); and (d) $L_y=5$, $(FBC_y,FBC_x)$ (open), where $FBC$, $PBC$, and $TPBC$ denote free, periodic, and twisted periodic boundary conditions, respectively. In the $L_x \to \infty$ limit of each strip we discuss the analytic structure of $W$ in the complex $q$ plane. The respective $W$ functions are evaluated numerically for various values of $q$. Several inferences are presented for the chromatic polynomials and analytic structure of $W$ for lattice strips with arbitrarily great $L_y$. The absence of a nonpathological $L_x \to \infty$ limit for real nonintegral $q$ in the interval $0 < q < 3$ ($0 < q < 4$) for strips of the square (triangular) lattice is discussed.Comment: 37 pages, latex, 4 encapsulated postscript figure

African-American mitochondrial DNAs often match mtDNAs found in multiple African ethnic groups

BACKGROUND: Mitochondrial DNA (mtDNA) haplotypes have become popular tools for tracing maternal ancestry, and several companies offer this service to the general public. Numerous studies have demonstrated that human mtDNA haplotypes can be used with confidence to identify the continent where the haplotype originated. Ideally, mtDNA haplotypes could also be used to identify a particular country or ethnic group from which the maternal ancestor emanated. However, the geographic distribution of mtDNA haplotypes is greatly influenced by the movement of both individuals and population groups. Consequently, common mtDNA haplotypes are shared among multiple ethnic groups. We have studied the distribution of mtDNA haplotypes among West African ethnic groups to determine how often mtDNA haplotypes can be used to reconnect Americans of African descent to a country or ethnic group of a maternal African ancestor. The nucleotide sequence of the mtDNA hypervariable segment I (HVS-I) usually provides sufficient information to assign a particular mtDNA to the proper haplogroup, and it contains most of the variation that is available to distinguish a particular mtDNA haplotype from closely related haplotypes. In this study, samples of general African-American and specific Gullah/Geechee HVS-I haplotypes were compared with two databases of HVS-I haplotypes from sub-Saharan Africa, and the incidence of perfect matches recorded for each sample. RESULTS: When two independent African-American samples were analyzed, more than half of the sampled HVS-I mtDNA haplotypes exactly matched common haplotypes that were shared among multiple African ethnic groups. Another 40% did not match any sequence in the database, and fewer than 10% were an exact match to a sequence from a single African ethnic group. Differences in the regional distribution of haplotypes were observed in the African database, and the African-American haplotypes were more likely to match haplotypes found in ethnic groups from West or West Central Africa than those found in eastern or southern Africa. Fewer than 14% of the African-American mtDNA sequences matched sequences from only West Africa or only West Central Africa. CONCLUSION: Our database of sub-Saharan mtDNA sequences includes the most common haplotypes that are shared among ethnic groups from multiple regions of Africa. These common haplotypes have been found in half of all sub-Saharan Africans. More than 60% of the remaining haplotypes differ from the common haplotypes at a single nucleotide position in the HVS-I region, and they are likely to occur at varying frequencies within sub-Saharan Africa. However, the finding that 40% of the African-American mtDNAs analyzed had no match in the database indicates that only a small fraction of the total number of African haplotypes has been identified. In addition, the finding that fewer than 10% of African-American mtDNAs matched mtDNA sequences from a single African region suggests that few African Americans might be able to trace their mtDNA lineages to a particular region of Africa, and even fewer will be able to trace their mtDNA to a single ethnic group. However, no firm conclusions should be made until a much larger database is available. It is clear, however, that when identical mtDNA haplotypes are shared among many ethnic groups from different parts of Africa, it is impossible to determine which single ethnic group was the source of a particular maternal ancestor based on the mtDNA sequence

Hybridization between wild and cultivated potato species in the Peruvian Andes and biosafety implications for deployment of GM potatoes

The nature and extent of past and current hybridization between cultivated potato and wild relatives in nature is of interest to crop evolutionists, taxonomists, breeders and recently to molecular biologists because of the possibilities of inverse gene flow in the deployment of genetically-modified (GM) crops. This research proves that natural hybridization occurs in areas of potato diversity in the Andes, the possibilities for survival of these new hybrids, and shows a possible way forward in case of GM potatoes should prove advantageous in such areas

Ribosome recycling, diffusion, and mRNA loop formation in translational regulation

We explore and quantify the physical and biochemical mechanisms that may be relevant in the regulation of translation. After elongation and detachment from the 3' termination site of mRNA, parts of the ribosome machinery can diffuse back to the initiation site, especially if it is held nearby, enhancing overall translation rates. The elongation steps of the mRNA-bound ribosomes are modeled using exact and asymptotic results of the totally asymmetric exclusion process (TASEP).Since the ribosome injection rates of the TASEP depend on the local concentrations at the initiation site, a source of ribosomes emanating from the termination end can feed back to the initiation site, leading to a self-consistent set of equations for the steady-state ribosome throughput. Additional mRNA binding factors can also promote loop formation, or cyclization, bringing the initiation and termination sites into close proximity. The probability distribution of the distance between the initiation and termination sites is described using simple noninteracting polymer models. We find that the initiation, or initial ribosome adsorption binding required for maximal throughput can vary dramatically depending on certain values of the bulk ribosome concentration and diffusion constant. If cooperative interactions among the loop-promoting proteins and the initiation/termination sites are considered, the throughput can be further regulated in a nonmonotonic manner. Potential experiments to test the hypothesized physical mechanisms are discussed.Comment: 21 pp, 11 .eps figs, realigned figures and magin

Molecular Insights into Division of Single Human Cancer Cells in On-Chip Transparent Microtubes.

In vivo, mammalian cells proliferate within 3D environments consisting of numerous microcavities and channels, which contain a variety of chemical and physical cues. External environments often differ between normal and pathological states, such as the unique spatial constraints that metastasizing cancer cells experience as they circulate the vasculature through arterioles and narrow capillaries, where they can divide and acquire elongated cylindrical shapes. While metastatic tumors cause most cancer deaths, factors impacting early cancer cell proliferation inside the vasculature and those that can promote the formation of secondary tumors remain largely unknown. Prior studies investigating confined mitosis have mainly used 2D cell culture systems. Here, we mimic aspects of metastasizing tumor cells dividing inside blood capillaries by investigating single-cell divisions of living human cancer cells, trapped inside 3D rolled-up, transparent nanomembranes. We assess the molecular effects of tubular confinement on key mitotic features, using optical high- and super-resolution microscopy. Our experiments show that tubular confinement affects the morphology and dynamics of the mitotic spindle, chromosome arrangements, and the organization of the cell cortex. Moreover, we reveal that membrane blebbing and/or associated processes act as a potential genome-safety mechanism, limiting the extent of genomic instability caused by mitosis in confined circumstances, especially in tubular 3D microenvironments. Collectively, our study demonstrates the potential of rolled-up nanomembranes for gaining molecular insights into key cellular events occurring in tubular 3D microenvironments in vivo.The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013)/ERC grant agreement no. 311529 (S.S.) and the Volkswagen Foundation no. 86 362 (S.S. and W.X.), a FEBS Return-to-Europe fellowship (C.K.S.), the Wellcome Trust (092096/Z/10/Z for N.L.; 094587/Z/10/Z for R.B.), and a European Research Council (ERC) Starting Researcher Grant (R.E.C.-S.; SYSGRO). O.G.S. acknowledges financial support from the DFG Research Unit 1713 “Sensorische Mikro und Nanosysteme”. D.H.G. acknowledges funding from the Alexander von Humboldt Foundation and the U.S. National Science Foundation (Grants: CMMI 1200241 and CBET-1442014). Research in the S.P.J. laboratory is funded by Cancer Research U.K., the ERC, and the European Community Seventh Framework Programme (DDResponse), with core infrastructure provided by Cancer Research U.K. and the Wellcome Trust.This is the final version of the article. It first appeared from the American Chemical Society via http://dx.doi.org/10.1021/acsnano.6b0046