The link between turbulence, magnetic fields, filaments, and star formation in the Central Molecular Zone cloud G0.253+0.016

Star formation is primarily controlled by the interplay between gravity, turbulence, and magnetic fields. However, the turbulence and magnetic fields in molecular clouds near the Galactic Center may differ substantially from spiral-arm clouds. Here we determine the physical parameters of the central molecular zone (CMZ) cloud G0.253+0.016, its turbulence, magnetic field and filamentary structure. Using column-density maps based on dust-continuum emission observations with ALMA+Herschel, we identify filaments and show that at least one dense core is located along them. We measure the filament width W_fil=0.17$\pm$0.08pc and the sonic scale {\lambda}_sonic=0.15$\pm$0.11pc of the turbulence, and find W_fil~{\lambda}_sonic. A strong velocity gradient is seen in the HNCO intensity-weighted velocity maps obtained with ALMA+Mopra, which is likely caused by large-scale shearing of G0.253+0.016, producing a wide double-peaked velocity PDF. After subtracting the gradient to isolate the turbulent motions, we find a nearly Gaussian velocity PDF typical for turbulence. We measure the total and turbulent velocity dispersion, 8.8$\pm$0.2km/s and 3.9$\pm$0.1km/s, respectively. Using magnetohydrodynamical simulations, we find that G0.253+0.016's turbulent magnetic field B_turb=130$\pm$50$\mu$G is only ~1/10 of the ordered field component. Combining these measurements, we reconstruct the dominant turbulence driving mode in G0.253+0.016 and find a driving parameter b=0.22$\pm$0.12, indicating solenoidal (divergence-free) driving. We compare this to spiral-arm clouds, which typically have a significant compressive (curl-free) driving component (b>0.4). Motivated by previous reports of strong shearing motions in the CMZ, we speculate that shear causes the solenoidal driving in G0.253+0.016 and show that this reduces the star formation rate (SFR) by a factor of 6.9 compared to typical nearby clouds

The link between solenoidal turbulence and slow star formation in G0.253+0.016

Star formation in the Galactic disc is primarily controlled by gravity, turbulence, and magnetic fields. It is not clear that this also applies to star formation near the Galactic Centre. Here we determine the turbulence and star formation in the CMZ cloud G0.253+0.016. Using maps of 3mm dust emission and HNCO intensity-weighted velocity obtained with ALMA, we measure the volume-density variance $\sigma_{\rho/\rho_0} = 1.3 \pm 0.5$ and turbulent Mach number $\mathcal{M} = 11 \pm 3$. Combining these with turbulence simulations to constrain the plasma $\beta = 0.34 \pm 0.35$, we reconstruct the turbulence driving parameter $b = 0.22 \pm 0.12$ in G0.253+0.016. This low value of $b$ indicates solenoidal (divergence-free) driving of the turbulence in G0.253+0.016. By contrast, typical clouds in the Milky Way disc and spiral arms have a significant compressive (curl-free) driving component ($b > 0.4$). We speculate that shear causes the solenoidal driving in G0.253+0.016 and show that this may reduce the star formation rate by a factor of 7 compared to nearby clouds

'The Brick' is not a brick: A comprehensive study of the structure and dynamics of the Central Molecular Zone cloud G0.253+0.016

In this paper we provide a comprehensive description of the internal dynamics of G0.253+0.016 (a.k.a. 'the Brick'); one of the most massive and dense molecular clouds in the Galaxy to lack signatures of widespread star formation. As a potential host to a future generation of high-mass stars, understanding largely quiescent molecular clouds like G0.253+0.016 is of critical importance. In this paper, we reanalyse Atacama Large Millimeter Array cycle 0 HNCO $J=4(0,4)-3(0,3)$ data at 3 mm, using two new pieces of software which we make available to the community. First, scousepy, a Python implementation of the spectral line fitting algorithm scouse. Secondly, acorns (Agglomerative Clustering for ORganising Nested Structures), a hierarchical n-dimensional clustering algorithm designed for use with discrete spectroscopic data. Together, these tools provide an unbiased measurement of the line of sight velocity dispersion in this cloud, $\sigma_{v_{los}, {\rm 1D}}=4.4\pm2.1$ kms$^{-1}$, which is somewhat larger than predicted by velocity dispersion-size relations for the Central Molecular Zone (CMZ). The dispersion of centroid velocities in the plane of the sky are comparable, yielding $\sigma_{v_{los}, {\rm 1D}}/\sigma_{v_{pos}, {\rm 1D}}\sim1.2\pm0.3$. This isotropy may indicate that the line-of-sight extent of the cloud is approximately equivalent to that in the plane of the sky. Combining our kinematic decomposition with radiative transfer modelling we conclude that G0.253+0.016 is not a single, coherent, and centrally-condensed molecular cloud; 'the Brick' is not a \emph{brick}. Instead, G0.253+0.016 is a dynamically complex and hierarchically-structured molecular cloud whose morphology is consistent with the influence of the orbital dynamics and shear in the CMZ

X-Ray Spectroscopy of Stars

(abridged) Non-degenerate stars of essentially all spectral classes are soft X-ray sources. Low-mass stars on the cooler part of the main sequence and their pre-main sequence predecessors define the dominant stellar population in the galaxy by number. Their X-ray spectra are reminiscent, in the broadest sense, of X-ray spectra from the solar corona. X-ray emission from cool stars is indeed ascribed to magnetically trapped hot gas analogous to the solar coronal plasma. Coronal structure, its thermal stratification and geometric extent can be interpreted based on various spectral diagnostics. New features have been identified in pre-main sequence stars; some of these may be related to accretion shocks on the stellar surface, fluorescence on circumstellar disks due to X-ray irradiation, or shock heating in stellar outflows. Massive, hot stars clearly dominate the interaction with the galactic interstellar medium: they are the main sources of ionizing radiation, mechanical energy and chemical enrichment in galaxies. High-energy emission permits to probe some of the most important processes at work in these stars, and put constraints on their most peculiar feature: the stellar wind. Here, we review recent advances in our understanding of cool and hot stars through the study of X-ray spectra, in particular high-resolution spectra now available from XMM-Newton and Chandra. We address issues related to coronal structure, flares, the composition of coronal plasma, X-ray production in accretion streams and outflows, X-rays from single OB-type stars, massive binaries, magnetic hot objects and evolved WR stars.Comment: accepted for Astron. Astrophys. Rev., 98 journal pages, 30 figures (partly multiple); some corrections made after proof stag

A mathematical and computational review of Hartree-Fock SCF methods in Quantum Chemistry

We present here a review of the fundamental topics of Hartree-Fock theory in Quantum Chemistry. From the molecular Hamiltonian, using and discussing the Born-Oppenheimer approximation, we arrive to the Hartree and Hartree-Fock equations for the electronic problem. Special emphasis is placed in the most relevant mathematical aspects of the theoretical derivation of the final equations, as well as in the results regarding the existence and uniqueness of their solutions. All Hartree-Fock versions with different spin restrictions are systematically extracted from the general case, thus providing a unifying framework. Then, the discretization of the one-electron orbitals space is reviewed and the Roothaan-Hall formalism introduced. This leads to a exposition of the basic underlying concepts related to the construction and selection of Gaussian basis sets, focusing in algorithmic efficiency issues. Finally, we close the review with a section in which the most relevant modern developments (specially those related to the design of linear-scaling methods) are commented and linked to the issues discussed. The whole work is intentionally introductory and rather self-contained, so that it may be useful for non experts that aim to use quantum chemical methods in interdisciplinary applications. Moreover, much material that is found scattered in the literature has been put together here to facilitate comprehension and to serve as a handy reference.Comment: 64 pages, 3 figures, tMPH2e.cls style file, doublesp, mathbbol and subeqn package

Expression of Trichoderma reesei β-Mannanase in Tobacco Chloroplasts and Its Utilization in Lignocellulosic Woody Biomass Hydrolysis

Lignocellulosic ethanol offers a promising alternative to conventional fossil fuels. One among the major limitations in the lignocellulosic biomass hydrolysis is unavailability of efficient and environmentally biomass degrading technologies. Plant-based production of these enzymes on large scale offers a cost-effective solution. Cellulases, hemicellulases including mannanases and other accessory enzymes are required for conversion of lignocellulosic biomass into fermentable sugars. β-mannanase catalyzes endo-hydrolysis of the mannan backbone, a major constituent of woody biomass. In this study, the man1 gene encoding β-mannanase was isolated from Trichoderma reesei and expressed via the chloroplast genome. PCR and Southern hybridization analysis confirmed site-specific transgene integration into the tobacco chloroplast genomes and homoplasmy. Transplastomic plants were fertile and set viable seeds. Germination of seeds in the selection medium showed inheritance of transgenes into the progeny without any Mendelian segregation. Expression of endo-β-mannanase for the first time in plants facilitated its characterization for use in enhanced lignocellulosic biomass hydrolysis. Gel diffusion assay for endo-β-mannanase showed the zone of clearance confirming functionality of chloroplast-derived mannanase. Endo-β-mannanase expression levels reached up to 25 units per gram of leaf (fresh weight). Chloroplast-derived mannanase had higher temperature stability (40°C to 70°C) and wider pH optima (pH 3.0 to 7.0) than E.coli enzyme extracts. Plant crude extracts showed 6–7 fold higher enzyme activity than E.coli extracts due to the formation of disulfide bonds in chloroplasts, thereby facilitating their direct utilization in enzyme cocktails without any purification. Chloroplast-derived mannanase when added to the enzyme cocktail containing a combination of different plant-derived enzymes yielded 20% more glucose equivalents from pinewood than the cocktail without mannanase. Our results demonstrate that chloroplast-derived mannanase is an important component of enzymatic cocktail for woody biomass hydrolysis and should provide a cost-effective solution for its diverse applications in the biofuel, paper, oil, pharmaceutical, coffee and detergent industries

Performance of the CMS Cathode Strip Chambers with Cosmic Rays

The Cathode Strip Chambers (CSCs) constitute the primary muon tracking device in the CMS endcaps. Their performance has been evaluated using data taken during a cosmic ray run in fall 2008. Measured noise levels are low, with the number of noisy channels well below 1%. Coordinate resolution was measured for all types of chambers, and fall in the range 47 microns to 243 microns. The efficiencies for local charged track triggers, for hit and for segments reconstruction were measured, and are above 99%. The timing resolution per layer is approximately 5 ns

Star formation in 'the Brick': ALMA reveals an active proto-cluster in the Galactic centre cloud G0.253+0.016

G0.253+0.016, aka 'the Brick', is one of the most massive (> 10^5 Msun) and dense (> 10^4 cm-3) molecular clouds in the Milky Way's Central Molecular Zone. Previous observations have detected tentative signs of active star formation, most notably a water maser that is associated with a dust continuum source. We present ALMA Band 6 observations with an angular resolution of 0.13" (1000 AU) towards this 'maser core', and report unambiguous evidence of active star formation within G0.253+0.016. We detect a population of eighteen continuum sources (median mass ~ 2 Msun), nine of which are driving bi-polar molecular outflows as seen via SiO (5-4) emission. At the location of the water maser, we find evidence for a protostellar binary/multiple with multi-directional outflow emission. Despite the high density of G0.253+0.016, we find no evidence for high-mass protostars in our ALMA field. The observed sources are instead consistent with a cluster of low-to-intermediate-mass protostars. However, the measured outflow properties are consistent with those expected for intermediate-to-high-mass star formation. We conclude that the sources are young and rapidly accreting, and may potentially form intermediate and high-mass stars in the future. The masses and projected spatial distribution of the cores are generally consistent with thermal fragmentation, suggesting that the large-scale turbulence and strong magnetic field in the cloud do not dominate on these scales, and that star formation on the scale of individual protostars is similar to that in Galactic disc environments

Primary versus secondary source of data in observational studies and heterogeneity in meta-analyses of drug effects: a survey of major medical journals

The data from individual observational studies included in meta-analyses of drug effects are collected either from ad hoc methods (i.e. "primary data") or databases that were established for non-research purposes (i.e. "secondary data"). The use of secondary sources may be prone to measurement bias and confounding due to over-the-counter and out-of-pocket drug consumption, or non-adherence to treatment. In fact, it has been noted that failing to consider the origin of the data as a potential cause of heterogeneity may change the conclusions of a meta-analysis. We aimed to assess to what extent the origin of data is explored as a source of heterogeneity in meta-analyses of observational studies.publishe