Influence of overlapping décollements, syn-tectonic sedimentation and structural inheritace in the evolution of contractional system: The central Kuqa fold-and-thrust bely (Tian Shan Mountains, NW China)

Contractional deformation in the Kuqa fold‐and‐thrust belt (southern foreland of the Tian Shan Mountains, NW China) is recorded by well‐preserved syntectonic continental sequences. In addition, its structural evolution was strongly controlled by synorogenic salt (Eocene in age) and presalt décollements with varying spatial distribution. We present a balanced and sequentially restored cross section across the central part of this fold‐and‐thrust belt that provides a new interpretation of the structure beneath the evaporites, in which Paleozoic and Mesozoic strata are deformed by a thrust stack involving (i) a thin‐skinned thrust system detached on Triassic‐Jurassic coal units and (ii) an ensemble of south‐directed basement thrusts. The latter formed from the inversion of Mesozoic extensional faults such as those preserved both in the Tarim foreland basin and beneath the frontal part of the Kuqa fold‐and‐thrust belt. The constructed section shows a total shortening of 35 km from the Late Cretaceous to the present. The restoration depicts a three‐stage evolution for the Kuqa fold‐and‐thrust belt: (i) minor Mesozoic extension, (ii) an early compressional stage (Late Cretaceous to early Miocene) with low shortening and syntectonic sedimentary rates, and (iii) a later compressional stage (late Pliocene‐Pleistocene) characterized by a greater and progressively increasing shortening rate and rapid deposition. Our results are discussed in light of previous analogue and numerical modeling studies and demonstrate the control exerted by the interplay between syntectonic sedimentation, the inversion of inherited basement structures, and the nature and extent of Triassic/Jurassic and Eocene décollements

Multidimensional Optical Sensing and Imaging Systems (MOSIS): From Macro to Micro Scales

Multidimensional optical imaging systems for information processing and visualization technologies have numerous applications in fields such as manufacturing, medical sciences, entertainment, robotics, surveillance, and defense. Among different three-dimensional (3-D) imaging methods, integral imaging is a promising multiperspective sensing and display technique. Compared with other 3-D imaging techniques, integral imaging can capture a scene using an incoherent light source and generate real 3-D images for observation without any special viewing devices. This review paper describes passive multidimensional imaging systems combined with different integral imaging configurations. One example is the integral-imaging-based multidimensional optical sensing and imaging systems (MOSIS), which can be used for 3-D visualization, seeing through obscurations, material inspection, and object recognition from microscales to long range imaging. This system utilizes many degrees of freedom such as time and space multiplexing, depth information, polarimetric, temporal, photon flux and multispectral information based on integral imaging to record and reconstruct the multidimensionally integrated scene. Image fusion may be used to integrate the multidimensional images obtained by polarimetric sensors, multispectral cameras, and various multiplexing techniques. The multidimensional images contain substantially more information compared with two-dimensional (2-D) images or conventional 3-D images. In addition, we present recent progress and applications of 3-D integral imaging including human gesture recognition in the time domain, depth estimation, mid-wave-infrared photon counting, 3-D polarimetric imaging for object shape and material identification, dynamic integral imaging implemented with liquid-crystal devices, and 3-D endoscopy for healthcare applications.B. Javidi wishes to acknowledge support by the National Science Foundation (NSF) under Grant NSF/IIS-1422179, and DARPA and US Army under contract number W911NF-13-1-0485. The work of P. Latorre Carmona, A. Martínez-Uso, J. M. Sotoca and F. Pla was supported by the Spanish Ministry of Economy under the project ESP2013-48458-C4-3-P, and by MICINN under the project MTM2013-48371-C2-2-PDGI, by Generalitat Valenciana under the project PROMETEO-II/2014/062, and by Universitat Jaume I through project P11B2014-09. The work of M. Martínez-Corral and G. Saavedra was supported by the Spanish Ministry of Economy and Competitiveness under the grant DPI2015-66458-C2-1R, and by the Generalitat Valenciana, Spain under the project PROMETEOII/2014/072

Dynamic Spectrum Sharing in Cognitive Radio Networks Using Truthful Mechanisms and Virtual Currency

In cognitive radio networks, there are scenarios where secondary users (SUs) utilize opportunistically the spectrum originally allocated to primary users (PUs). The spectrum resources available to SUs fluctuates over time due to PUs activity, SUs mobility and competition between SUs. In order to utilize these resources efficiently spectrum sharing techniques need to be implemented. In this paper we present an approach based on game-theoretical mechanism design for dynamic spectrum sharing. Each time a channel is not been used by any PU, it is allocated to SUs by a central spectrum manager based on the valuations of the channel reported by all SUs willing to use it. When an SU detects a free channel, it estimates its capacity according to local information and sends the valuation of it to the spectrum manager. The manager calculates a conflict-free allocation by implementing a truthful mechanism. The SUs have to pay for the allocation an amount which depends on the set of valuations. The objective is not to trade with the spectrum, but to share it according to certain criteria. For this, a virtual currency is defined and therefore monetary payments are not necessary. The spectrum manager records the credit of each SU and redistributes the payments to them after each spectrum allocation. The mechanism restricts the chances of each SU to be granted the channel depending on its credit availability. This credit restriction provides an incentive to SUs to behave as benefit maximizers. If the mechanism is truthful, their best strategy is to communicate the true valuation of the channel to the manager, what makes possible to implement the desired spectrum sharing criteria. We propose and evaluate an implementation of this idea by using two simple mechanisms which are proved to be truthful, and that are tractable and approximately efficient. We show the flexibility of these approach by illustrating how these mechanisms can be modified to achieve different sharing objectives which are trade-offs between efficiency and fairness. We also investigate how the credit restriction and redistribution affects the truthfulness of these mechanisms.This work was supported by the Spanish government through Projects TIN 2008-06739-C04-02 and TIN 2010-21378-C02-02.Vidal Catalá, JR.; Pla, V.; Guijarro Coloma, LA.; Martínez Bauset, J. (2013). Dynamic Spectrum Sharing in Cognitive Radio Networks Using Truthful Mechanisms and Virtual Currency. Ad Hoc Networks. 11:1858-1873. https://doi.org/10.1016/j.adhoc.2013.04.010S185818731

Influence of Syntectonic sedimentation and décollement rheology on the geometry and evolution of orogenic wedges: analog modelling of the Kuqa Fold-and-thrust belt (NW China)

Contractional deformation in the outer parts of fold‐and‐thrust belts is in part controlled by the presence of syntectonic sediments and multiple décollements (e.g., the Apennines, the Appalachians, the Pyrenees, the Zagros, or the Sub‐Andean and Kuqa fold‐and‐thrust belts). To better understand the influence of these parameters in the kinematic evolution of fold‐and‐thrust systems, we carried out an experimental study including four 3‐D sandbox models inspired by one of the previously mentioned prototypes, the Kuqa fold‐and‐thrust belt. This belt contains two décollements: a weak synorogenic salt layer and a deeper, preorogenic, and frictionless décollement (i.e., organic‐rich shales) showing along strike variations of rheology. The experimental results show that increasing synkinematic sedimentation rate (i) generates a progressive change from distributed to localized deformation and (ii) delays the development of frontal contractional structures detached on the salt, favoring the formation and reactivation of more hinterland thrusts and backthrusts. With respect to the rheology, our study reveals that as the viscosity of the prekinematic décollement increases, (i) the deformation propagates more slowly toward the foreland, and (ii) the underlying thrust stack becomes broader and lower and has a gentler thrust taper angle. The rheology of the prekinematic décollement defines the distribution and geometry of the structures detached on it that in turn influence the development of overlying, salt‐detached structures. Subsalt structures can (i) determine the areal extent of the salt and therefore of any fold‐and‐thrust system detached on it and (ii) hamper or even prevent the progressive foreland propagation of deformation above the salt

A multiscale hybrid model for pro-angiogenic calcium signals in a vascular endothelial cell

Cytosolic calcium machinery is one of the principal signaling mechanisms by which endothelial cells (ECs) respond to external stimuli during several biological processes, including vascular progression in both physiological and pathological conditions. Low concentrations of angiogenic factors (such as VEGF) activate in fact complex pathways involving, among others, second messengers arachidonic acid (AA) and nitric oxide (NO), which in turn control the activity of plasma membrane calcium channels. The subsequent increase in the intracellular level of the ion regulates fundamental biophysical properties of ECs (such as elasticity, intrinsic motility, and chemical strength), enhancing their migratory capacity. Previously, a number of continuous models have represented cytosolic calcium dynamics, while EC migration in angiogenesis has been separately approached with discrete, lattice-based techniques. These two components are here integrated and interfaced to provide a multiscale and hybrid Cellular Potts Model (CPM), where the phenomenology of a motile EC is realistically mediated by its calcium-dependent subcellular events. The model, based on a realistic 3-D cell morphology with a nuclear and a cytosolic region, is set with known biochemical and electrophysiological data. In particular, the resulting simulations are able to reproduce and describe the polarization process, typical of stimulated vascular cells, in various experimental conditions.Moreover, by analyzing the mutual interactions between multilevel biochemical and biomechanical aspects, our study investigates ways to inhibit cell migration: such strategies have in fact the potential to result in pharmacological interventions useful to disrupt malignant vascular progressio

Recruitment Constraints in Singapore's Fluted Giant Clam (Tridacna squamosa) Populations - A Dispersal Model Approach

10.1371/journal.pone.0058819PLoS ONE83

Acute loss of TET function results in aggressive myeloid cancer in mice

TET-family dioxygenases oxidize 5-methylcytosine (5mC) in DNA, and exert tumour suppressor activity in many types of cancers. Even in the absence of TET coding region mutations, TET loss-of-function is strongly associated with cancer. Here we show that acute elimination of TET function induces the rapid development of an aggressive, fully-penetrant and cell-autonomous myeloid leukaemia in mice, pointing to a causative role for TET loss-of-function in this myeloid malignancy. Phenotypic and transcriptional profiling shows aberrant differentiation of haematopoietic stem/progenitor cells, impaired erythroid and lymphoid differentiation and strong skewing to the myeloid lineage, with only a mild relation to changes in DNA modification. We also observe progressive accumulation of phospho-H2AX and strong impairment of DNA damage repair pathways, suggesting a key role for TET proteins in maintaining genome integrityopen0

Roadmap on 3D integral imaging: Sensing, processing, and display

This Roadmap article on three-dimensional integral imaging provides an overview of some of the research activities in the field of integral imaging. The article discusses various aspects of the field including sensing of 3D scenes, processing of captured information, and 3D display and visualization of information. The paper consists of a series of 15 sections from the experts presenting various aspects of the field on sensing, processing, displays, augmented reality, microscopy, object recognition, and other applications. Each section represents the vision of its author to describe the progress, potential, vision, and challenging issues in this field