Leadership and capability development and deployment in the New Zealand State Service

This article describes the design during 2013 of a model and implementation principles of a leadership and capability development and deployment (LCDD) model for the state services system. In this process, an initial prototype model was developed to describe a desired future state. It was informed by the best traditions of state services leadership development, together with models used by the world’s best companies, such as Procter & Gamble, for leadership development (Filipkowski and Donlon, 2013). The model was then enhanced based on our research in other jurisdictions, including Australia, Singapore and the United Kingdom, and co-creation with stakeholders. This is further discussed in the article. Dr Mike Pratt is Professor of Leadership and Sustainability at the University of Waikato, and a professional director and business adviser. Dr Murray Horn is a former Secretary to the Treasury of New Zealand and bank chief executive, and a professional director and business adviser

Relative numbers of cortical and brainstem inputs to the lateral geniculate nucleus

ABSTRACT Terminals of a morphological type known as RD (for round vesicles and dense mitochondria, which we define here as the aggregate of types formerly known as RSD and RLD, where ''S'' is small and ''L'' is large) constitute at least half of the synaptic inputs to the feline lateral geniculate nucleus, which represents the thalamic relay of retinal input to cortex. It had been thought that the vast majority of these RD terminals were of cortical origin, making the corticogeniculate pathway by far the largest source of input to geniculate relay cells. However, another source of RD terminals recently identified derives from cholinergic cells of the brainstem parabrachial region. (These cells also contain NO.) We used techniques of electron microscopy to determine quantitatively the relative contribution of cortex and brainstem to the population of RD terminals. We identified corticogeniculate terminals by orthograde transport of biocytin injected into the visual cortex and identified brainstem terminals by immunocytochemical labeling for choline acetyltransferase or brain NO synthase (the synthesizing enzymes for acetylcholine and NO, respectively). We estimated the relative numbers of corticogeniculate and brainstem terminals with a two-step algorithm: First, we determined the relative probability of sampling each terminal type in our material, and then we calculated what mixture of identified corticogeniculate and brainstem terminals was needed to recreate the size distribution of the parent RD terminal population. We conclude that brainstem terminals comprise roughly one-half of the RD population. Thus, the cortical input is perhaps half as large and the brainstem input is an order of magnitude larger than had been thought. This further suggests that the brainstem inputs might play a surprisingly complex and subtle role in the control of the geniculocortical relay. It is often claimed that terminals from visual cortex form the dominant input to the lateral geniculate nucleus, which is the thalamic relay of retinal input to the visual cortex (1-4). This is because corticogeniculate axons end in a characteristic type of synaptic terminal we shall refer to as ''RD'' (for round vesicles and dense mitochondria), and RD terminals are the majority found in the geniculate neuropil (1, 2, 4, 5). The RD terminal type represents an aggregate of what was previously defined as RSD and RLD terminals (1, 6), where the ''S'' and ''L'' refer to small and large, respectively. However, we have shown that, based on size, RSD and RLD terminals form a continuum (6) and that there is thus little justification for separating them, so we prefer to lump them together under the new term ''RD.'' Until recently, few candidate sources for RD terminals other than corticogeniculate axons have been identified, and it has been assumed that nearly all of these emanate in the feedback pathway from visual cortex (refs. 1-4 but also see ref. 7). As a result, many functions have been suggested for the corticothalamic pathway in controlling or modifying the thalamic relay (reviewed in ref. 5), and other extrathalamic sources of input have been relegated a less important role. However, we now know that cholinergic terminals from the parabrachial region of the brainstem also display RD morphology, but we have lacked quantitative data permitting us to determine what proportion of the dominant RD terminal population is cortical vs. brainstem in origin. Using material from the cat's lateral geniculate nucleus, we used an algorithm based on size distributions of RD terminals identified as deriving from cortical neurons or from cholinergic brainstem neurons, and we conclude that the brainstem contribution is much greater than previously thought, providing approximately half of the RD terminals. We suggest that, although the corticothalamic input is large, it is not as dominant as once thought, and inputs from the brainstem are much more important in the geniculate relay than has been appreciated. Our basic methods have been fully described elsewher

Dynamics of pebbles in the vicinity of a growing planetary embryo: hydro-dynamical simulations

Understanding the growth of the cores of giant planets is a difficult problem. Recently, Lambrechts and Johansen (2012; LJ12) proposed a new model in which the cores grow by the accretion of pebble-size objects, as the latter drift towards the star due to gas drag. Here, we investigate the dynamics of pebble-size objects in the vicinity of planetary embryos of 1 and 5 Earth masses and the resulting accretion rates. We use hydrodynamical simulations, in which the embryo influences the dynamics of the gas and the pebbles suffer gas drag according to the local gas density and velocities. The pebble dynamics in the vicinity of the planetary embryo is non-trivial, and it changes significantly with the pebble size. Nevertheless, the accretion rate of the embryo that we measure is within an order of magnitude of the rate estimated in LJ12 and tends to their value with increasing pebble-size. We conclude that the model by LJ12 has the potential to explain the rapid growth of giant planet cores. The actual accretion rates however, depend on the surface density of pebble size objects in the disk, which is unknown to date.Comment: In press in Astronomy and Astrophysic

On the tidal environment of an outwardly migrating F ring

Saturn’s F-ring is a unique narrow ring that lies radially close to the tidally disruptive Roche limit of Saturn for water ice. Significant work has been done on the system that shows it to be one of the most dynamic places in the Solar System. Aggregates fortunate enough to form constantly battle against the strong tidal forces of Saturn and the nearby moons Prometheus and Pandora, which act to gravitationally stir up ring material. Planetary rings are also known to radially spread, with the outer ring edge migrating outwards. As the F ring lies at the edge of the main rings, we investigate the effect of an outwardly migrated F ring and its interaction with Prometheus. For each model with decreasing local tidal environment, an increase in maximum number density of particles at the channel edges is observed. In the same locations as particles with maximum number densities, radial velocity dispersion's are observed to fall below escape velocities of a 150m icy moonlet (<10 cm s^(-1)), and are gravitationally unstable with Toomre parameters Q<2. Additionally, in locations of the ring where Q<2 is observed, more particles are seen to fall below or close to critical values as the radial location of the ring increases

Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism

© 2015 Wiley Periodicals, Inc. Acknowledgement Grant sponsor: State of Lower Saxony-Israel Research Cooperation; Grant number: ZN2035; Grant sponsor:German Research Council; Grant number: SFB/TRR43 and FOR1336; Grant sponsor: Parkinson UK; Grant number: K-1001; Grant sponsor: ProFutura Program (University of Gottingen); Grant sponsor: Else Kroner Fresenius Stiftung;Grant number: A69/2010; Grant sponsor: DFG; Grant number: WE 3547/4–1; Grant sponsor: US National Multiple Sclerosis Society; Grant numbers: NMSS; PP 1660. The authors thank Elke Pralle, Susanne Kiecke and Caroline Jaß (University of Gottingen) for excellent technical assistance.Peer reviewedPostprin

Children's Norm Enforcement in Their Interactions With Peers

This study investigates how children negotiate social norms with peers. In Study 1, 48 pairs of 3- and 5-year-olds (N = 96) and in Study 2, 48 pairs of 5- and 7-year-olds (N = 96) were presented with sorting tasks with conflicting instructions (one child by color, the other by shape) or identical instructions. Three-year-olds differed from older children: They were less selective for the contexts in which they enforced norms, and they (as well as the older children to a lesser extent) used grammatical constructions objectifying the norms (“It works like this” rather than “You must do it like this”). These results suggested that children's understanding of social norms becomes more flexible during the preschool years.Psycholog

The measurement of psychological literacy: A first approximation

Psychological literacy, the ability to apply psychological knowledge to personal, family, occupational, community and societal challenges, is promoted as the primary outcome of an undergraduate education in psychology. As the concept of psychological literacy becomes increasingly adopted as the core business of undergraduate psychology training courses world-wide, there is urgent need for the construct to be accurately measured so that student and institutional level progress can be assessed and monitored. Key to the measurement of psychological literacy is determining the underlying factor-structure of psychological literacy. In this paper we provide a first approximation of the measurement of psychological literacy by identifying and evaluating self-report measures for psychological literacy. Multi-item and single-item self-report measures of each of the proposed nine dimensions of psychological literacy were completed by two samples (N = 218 and N = 381) of undergraduate psychology students at an Australian university. Single and multi-item measures of each dimension were weakly to moderately correlated. Exploratory and confirmatory factor analyses of multi-item measures indicated a higher order three factor solution best represented the construct of psychological literacy. The three factors were reflective processes, generic graduate attributes, and psychology as a helping profession. For the measurement of psychological literacy to progress there is a need to further develop self-report measures and to identify/develop and evaluate objective measures of psychological literacy. Further approximations of the measurement of psychological literacy remain an imperative, given the construct's ties to measuring institutional efficacy in teaching psychology to an undergraduate audience

Enterococcal meningitis caused by Enterococcus casseliflavus. First case report

BACKGROUND: Enterococcal meningitis is an uncommon disease usually caused by Enterococcus faecalis and Enterococcus faecium and is associated with a high mortality rate. Enterococcus casseliflavus has been implicated in a wide variety of infections in humans, but never in meningitis. CASE PRESENTATION: A 77-year-old Italian female presented for evaluation of fever, stupor, diarrhea and vomiting of 3 days duration. There was no history of head injury nor of previous surgical procedures. She had been suffering from rheumatoid arthritis for 30 years, for which she was being treated with steroids and methotrexate. On admission, she was febrile, alert but not oriented to time and place. Her neck was stiff, and she had a positive Kernig's sign. The patient's cerebrospinal fluid was opalescent with a glucose concentration of 14 mg/dl, a protein level of 472 mg/dl, and a white cell count of 200/μL with 95% polymorphonuclear leukocytes and 5% lymphocytes. Gram staining of CSF revealed no organisms, culture yielded E. casseliflavus. The patient was successfully treated with meropenem and ampicillin-sulbactam. CONCLUSIONS: E. casseliflavus can be inserted among the etiologic agents of meningitis. Awareness of infection of central nervous system with Enterococcus species that possess an intrinsic vancomycin resistance should be increased