Art and devotion around death. The brotherhood of souls of Los Realejos

Las cofradías de ánimas de las dos principales parroquias de Los Realejos han marcado el devenir de sus templos. Sus imponentes cuadros de ánimas, retablos e imágenes asociadas a ellos han marcado la vida parroquial durante siglos. La fundación de ambas confraternidades, a partir de una idea después de la muerte y del culto a las almas que se encontraban en el purgatorio para poder alcanzar la gloria, es el origen de estos cultos. Además, su crecimiento patrimonial, en el caso del Realejo Alto mayor que en Realejo Bajo, acabaría por dotar a ambas parroquias de una importante fuente patrimonial hasta su desaparición durante los siglos xix y xx, quedando los vestigios que hoy conservamos en la parroquia de Santiago y que el fuego arrasó en el caso de la parroquia de la Concepción.The brotherhoods of souls of parishes of Los Realejos they have marked the history of their temples. His imposing paintings of souls, altarpieces, and sculptures have marked the parish life for centuries. The fundation of both brotherghoods, from a idea after death and the cult of souls of Purgatory to be able to achieve glory is the origin of these cults. In addition, its patrimonial growth, in the case of Realejo Alto is greater than Realejo Bajo, it would end up giving both parishes until their disappearance during the century 19th and 20th, remaining the vestiges that today we conserve in de parish of Santiago and that the fire burned in the parish of the Conception

For the sufrague and relief of deceased. Sibling priests saint peter’s brotherhood in La Laguna and it’s reflex in Tenerife

Las cofradías de sacerdotes son un eslabón más dentro de las instituciones gremiales que surgieron durante el Antiguo Régimen. A raíz de la fundación de la primera confraternidad en la parroquia de Nuestra Señora de la Concepción de La Laguna, fueron naciendo más por los distintos templos, en especial los del norte de la isla de Tenerife. Las normas que las regían, los cultos del Martes Santo en honor de las Lágrimas de San Pedro y el patrimonio que desarrollaron son los principales ejes de este artículo.The priest’s brotherhood are a link more inside the union institutions which appears during the Old Regimen (es nombre propio, también se puede poner en español pero me suena mejor en inglés en línea con el texto). Since the foundation of the first fellowship in Nuestra Señora de la Concepción in La Laguna’s chunch were born more ones by the different churches, in special in the north of Tenerife. The rules which followed them, Saint Tuesday’s workship in honor of Saint Peter’s tears and the heritage which developed are the main points of Thais article

A de novo transcriptional atlas in Danaus plexippus reveals variability in dosage compensation across tissues

A detailed knowledge of gene function in the monarch butterfly is still lacking. Here we generate a genome assembly from a Mexican nonmigratory population and used RNA-seq data from 14 biological samples for gene annotation and to construct an atlas portraying the breadth of gene expression during most of the monarch life cycle. Two thirds of the genes show expression changes, with long noncoding RNAs being particularly finely regulated during adulthood, and male-biased expression being four times more common than female-biased. The two portions of the monarch heterochromosome Z, one ancestral to the Lepidoptera and the other resulting from a chromosomal fusion, display distinct association with sex-biased expression, reflecting sample-dependent incompleteness or absence of dosage compensation in the ancestral but not the novel portion of the Z. This study presents extended genomic and transcriptomic resources that will facilitate a better understanding of the monarch's adaptation to a changing environment

Respuesta clínica y bioquímica al manejo de macroprolactinomas en hombres latinoamericanos, Cali, Colombia y la Habana, Cuba

Introducción: los prolactinomas son los tumores hipofisiarios productores más comunes en la práctica clínica. Aunque son más comunes en mujeres, en hombres su comportamiento es distinto, más agresivo y con una respuesta al tratamiento farmacológico incierta. Objetivo: describir las características clínicas y bioquímicas, y la respuesta al tratamiento farmacológico y quirúrgico de un grupo de hombres con macroprolactinomas invasivos. Materiales y métodos: se realizó un estudio de cohorte retrospectivo con los datos clínicos de hombres con diagnóstico de macroprolactinomas invasivos de la Clínica de Enfermedades Hipofisiarias del Instituto Nacional de Endocrinología en Habana, Cuba y de la Clínica Imbanaco en Cali, Colombia (2022-2017), con un rango de edad entre 10-80 años. Se realizó un análisis de las características demográficas, clínicas, signos, síntomas, perfil bioquímico hormonal, imágenes por resonancia magnética de la anatomía de la región hipotálamo-hipofisaria y tratamiento médico y quirúrgico. Se estimaron proporciones y medidas de tendencia central por medio de análisis univariado. Se comparó los dos tipos de tratamiento con las pruebas T de student o Kruskal Wallis. Resultados: se analizaron 30 hombres, la edad media fue 44±13,8 años; 5,2 ±4,1 años de evolución de la enfermedad; 96 % presentaron cefalea, 80 % hipopituitarismo. La prolactina sérica inicial media fue 487?g/L. Se realizó tratamiento con cirugía más agonistas de dopamina en el 53 %, con una disminución del 86 % y 96 % en la prolactina sérica a los 6 y 12 meses, respectivamente; mientras que los pacientes que recibieron agonistas de la dopamina tuvieron una disminución del 71 % y 95 % en la prolactina sérica a los 6 y 12 meses, respectivamente. Inicialmente los pacientes con tratamiento quirúrgico obtuvieron una mayor reducción del tamaño tumoral, pero no hubo diferencias al año de seguimiento. Conclusión: el tratamiento combinado con cirugía más agonistas de dopaminérgicos no tuvo una mayor reducción los niveles de prolactina durante el primer año de tratamiento, independiente del tamaño tumoral. En pacientes hombres con macroprolactinomas invasivos el tratamiento farmacológico con agonistas de la dopamina es el tratamiento de elección de primera línea

Knowledge transfer activities in social sciences and humanities: Explaining the interactions of research groups with non-academic agents

The aim of this research is to achieve a better understanding of the processes underlying knowledge transfer (KT) in social sciences and humanities (SSH). The paper addresses: first, the extent of SSH research groups' engagement in KT and the formal KT activities used to interact with non-academic communities; and second, how the characteristics of research groups may influence engagement in various types of KT. The empirical analysis is at research group level using data derived from a questionnaire of SSH research groups belonging to the Spanish Council for Scientific Research (CSIC). We find that KT activities are based on relational rather than commercial activities. The most frequent relational activities in which SSH research groups engage are consultancy and contract research. We find also that the characteristics of research groups (e.g. size and multidisciplinarity) and individuals (e.g. academic status and star scientist) are associated with involvement in KT activities and that a deliberate focus on the societal impacts and relevance of the research conducted is strongly related to active engagement of research groups in all the modes of KT considered in this study. From a managerial perspective, our findings suggest that measures promoting a focus on the societal impact of research could enhance research groups' engagement in KT activitiesOlmos-Peñuela, J.; Castro-Martinez, E.; Deste Cukierman, P. (2014). Knowledge transfer activities in social sciences and humanities: Explaining the interactions of research groups with non-academic agents. Research Policy. 43(4):696-706. doi:10.1016/j.respol.2013.12.004S69670643

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Networked together: designing participatory research in on-line ethnography

Abstract. This book contains the conference proceedings of the third edition of Rethinking Educational Ethnography: Researching on-line communities and interactions Conference hold in Napoli from 6th to 7th of June 2013. In 2013, the third edition of the Conference has invited ethnographers in different fields of research (not only in education), and those involved in ethnographic investigations in diverse disciplines (anthropology, sociology, etc.) to present and discuss contributions on the challenges of participatory research design in digital ethnography

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe