Some aspects of the nature and extent of absentee land ownership in Antelope County, Nebraska

The issue of absentee ownership of farm land has become increasingly important to the people of Nebraska. At the time of this writing, a movement is underway to seek a constitutional amendment that would prohibit further land acquisition by nonfamily-owned corporations. The movement is led by such organizations as the Nebraska Farmers Union and the National Farmers Organization. Several surrounding states, including North Dakota, South Dakota, Minnesota, Wisconsin, Iowa, Missouri, Oklahoma, and Kansas, already have enacted similar laws. This study examines the nature and extent of absentee farm ownership in Antelope County, Nebraska, for the purpose of assessing the impact of absentee ownership. In other words, is there a discernible difference between local ownership and absentee ownership of farm land

Consumers Ask: Should I Purchase Long-Term Care Insurance?

Seventy million baby-boomers may face the need for long-term care (LTC). Therefore, educating them about long-term care insurance (LTCI) is necessary considering the high costs of LTC services and the aggressive marketing of LTCI by companies. It is important that consumers receive unbiased information regarding LTCI and how it fits into their personal financial situation. Seminars using the Should I Purchase Long-Term Care Insurance? presentation and accompanying Comparing Long-Term Care Insurance worksheet have helped Idahoans: (1) become more knowledgeable about LTCI, (2) decide if LTCI is right for them, and (3) learn how to effectively shop for and compare LTCI

A Model for Youth Financial Education in Extension Involving a Game-Based Approach

University of Idaho Extension educators have developed a library of 10 game-based personal finance programs, collectively known as the Northwest Youth Financial Education project, and have made these programs freely available for Extension educators to use. The purpose of this article is to share highlights from an associated train-the-trainer event and the impacts of one of the 10 programs as it has begun to be implemented. The Northwest Youth Financial Education project serves as a model for effective and engaging youth personal finance education that can be easily implemented or replicated in Extension

Youths Learn Responsible Use of Credit Cards

The need for youth credit card education is clear given the many statistics indicating increasing credit card debt and an overall scarcity of credit card education targeting youths. The Teen$ Credit Card simulation program offers youths an opportunity to experience owning a credit card, using it, and realizing the consequences of carrying a high balance from month to month. Participants have a chance to discover the benefits and detriments of using a credit card in a safe environment before potentially making mistakes in real life. University of Idaho Extension educators have presented this program to over 550 youths in a variety of settings, with evaluation results indicating self-assessed increases in knowledge and planned positive behavior changes

Educating Idahoans to Make Their Own Estate Planning Decisions

To address the need for estate planning education, University of Idaho Extension partnered with community organizations, local attorneys, and health care professionals to conduct unbiased, low-cost seminars that teach important legal end-of-life concepts and skills. Using the award-winning Legally Secure Your Financial Future: Organize, Communicate, Prepare (LSYFF) curriculum, 19 seminars were offered to nearly 1,600 participants throughout Idaho. Instructors guided seminar participants through an evaluation of their important documents and legal decisions, taught estate planning concepts, motivated attendees to communicate legal end-of-life wishes, and provided references for self-help or professional assistance

Tidal Dissipation in the Early Eocene and Implications for Ocean Mixing

The tidally driven vertical diffusivity in the abyssal ocean during the early Eocene (55 Ma) is investigated using an established tidal model. A weak tide is predicted in the Eocene ocean, except in the Pacific. Consequently, the integrated global tidal dissipation rate is a mere 1.44TW, of which 40% dissipate in the Pacific. However, due to a stronger abyssal vertical stratification the predicted Eocene vertical diffusivities are consistently larger than at present. The results support the hypothesis that altered tidal dissipation may play a role in explaining the maintenance of past climate regimes, especially the anomalously warm temperatures in the southwest Pacific in the Eocene, and the low dissipation rates may be important for lunar evolution history

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function. METHODS: We performed GWAS of the rate of change in forced expiratory volume in the first second (FEV1) in 14 longitudinal, population-based cohort studies comprising 27,249 adults of European ancestry using linear mixed effects model and combined cohort-specific results using fixed effect meta-analysis to identify novel genetic loci associated with longitudinal change in lung function. Gene expression analyses were subsequently performed for identified genetic loci. As a secondary aim, we estimated the mean rate of decline in FEV1 by smoking pattern, irrespective of genotypes, across these 14 studies using meta-analysis. RESULTS: The overall meta-analysis produced suggestive evidence for association at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P  =  5.71 × 10(-7)). In addition, meta-analysis using the five cohorts with ≥3 FEV1 measurements per participant identified the novel ME3 locus on chromosome 11 (P  =  2.18 × 10(-8)) at genome-wide significance. Neither locus was associated with FEV1 decline in two additional cohort studies. We confirmed gene expression of IL16, STARD5, and ME3 in multiple lung tissues. Publicly available microarray data confirmed differential expression of all three genes in lung samples from COPD patients compared with controls. Irrespective of genotypes, the combined estimate for FEV1 decline was 26.9, 29.2 and 35.7 mL/year in never, former, and persistent smokers, respectively. CONCLUSIONS: In this large-scale GWAS, we identified two novel genetic loci in association with the rate of change in FEV1 that harbor candidate genes with biologically plausible functional links to lung function

Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study

<p>Abstract</p> <p>Background</p> <p>Mannose-binding lectin (MBL) forms an integral part of the innate immune system. Persistent, subclinical infections and chronic inflammatory states are hypothesized to contribute to the pathogenesis of atherosclerosis. MBL gene (<it>MBL2</it>) variants with between 12 to 25% allele frequency in Caucasian and other populations, result in markedly reduced expression of functional protein. Prospective epidemiologic studies, including a nested, case-control study from the present population, have demonstrated the ability of <it>MBL2 </it>genotypes to predict complications of atherosclerosis,. The genetic control of <it>MBL2 </it>expression is complex and genetic background effects in specific populations are largely unknown.</p> <p>Methods</p> <p>The Strong Heart Study is a longitudinal, cohort study of cardiovascular disease among American Indians. A subset of individuals genotyped for the above mentioned case-control study were selected for analysis of circulating MBL levels by double sandwich ELISA method. Mean MBL levels were compared between genotypic groups and multivariate regression was used to determine other independent factors influencing <it>MBL2 </it>expression.</p> <p>Results</p> <p>Our results confirm the effects of variant structural (B, C, and D) and promoter (H and Y) alleles that have been seen in other populations. In addition, MBL levels were found to be positively associated with male gender and hemoglobin A1c levels, but inversely related to triglyceride levels. Correlation was not found between MBL and other markers of inflammation.</p> <p>Conclusion</p> <p>New data is presented concerning the effects of known genetic variants on MBL levels in an American Indian population, as well as the relationship of <it>MBL2 </it>expression to clinical and environmental factors, including inflammatory markers.</p

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and indices of beta-cell function (HOMA-B) and insulin resistance (HOMA-IR) in up to 46,186 nondiabetic participants. Follow-up of 25 loci in up to 76,558 additional subjects identified 16 loci associated with fasting glucose and HOMA-B and two loci associated with fasting insulin and HOMA-IR. These include nine loci newly associated with fasting glucose (in or near ADCY5, MADD, ADRA2A, CRY2, FADS1, GLIS3, SLC2A2, PROX1 and C2CD4B) and one influencing fasting insulin and HOMA-IR (near IGF1). We also demonstrated association of ADCY5, PROX1, GCK, GCKR and DGKB-TMEM195 with type 2 diabetes. Within these loci, likely biological candidate genes influence signal transduction, cell proliferation, development, glucose-sensing and circadian regulation. Our results demonstrate that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes

Calcium isotope (δ^44/40Ca ) variations of Neogene planktonic foraminifera

Measurements of the calcium isotopic composition (δ44/40Ca) of planktonic foraminifera from the western equatorial Pacific and the Indian sector of the Southern Ocean show variations of about 0.6‰ over the past 24 Myr. The stacked δ44/40Ca record of Globigerinoides trilobus and Globigerina bulloides indicates a minimum in δ44/40Casw (seawater calcium) at 15 to 16 Ma and a subsequent general increase toward the present, interrupted by a second minimum at 3 to 5 Ma. Applying a coupled calcium/carbon cycle model, we find two scenarios that can explain a large portion of the observed δ44/40Casw variations. In both cases, variations in the Ca input flux to the ocean without proportional changes in the carbonate flux are invoked. The first scenario increases the riverine calcium input to the ocean without a proportional increase of the carbonate flux. The second scenario generates an additional calcium flux from the exchange of Ca by Mg during dolomitization. In both cases the calcium flux variations lead to drastic changes in the seawater Ca concentrations on million year timescales. Our δ44/40Casw record therefore indicates that the global calcium cycle may be much more dynamic than previously assumed