1,427 research outputs found

    Orthogonality Effects in Relativistic Models of Nucleon Knockout Reactions

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    We study the effect of wave function orthogonality in the relativistic treatment of the nucleon removal reactions (gamma, p) and (e, e' p). The continuum wave function describing the outgoing nucleon is made orthogonal to the relevant bound states using the Gram-Schmidt procedure. This procedure has the advantage of preserving the asymptotic character of the continuum wave function and hence the elastic observables are unaffected. The orthogonality effects are found to be negligible for (e, e' p) reactions for missing momenta up to 700 MeV/c. This holds true for both parallel and perpendicular kinematics. By contrast the orthogonalization of the wave functions appears to have a more pronounced effect in the case of (gamma, p) reactions. We find that the orthogonality effect can be significant in this case particularly for large angles. Polarization of the outgoing protons and photon asymmetry show more sensitivity than the cross sections. If the orthogonality condition is imposed solely on this one hole state the effects are usually smaller.Comment: LaTeX, 7 postscript figure

    Single electron magneto-conductivity of a nondegenerate 2D electron system in a quantizing magnetic field

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    We study transport properties of a non-degenerate two-dimensional system of non-interacting electrons in the presence of a quantizing magnetic field and a short-range disorder potential. We show that the low-frequency magnetoconductivity displays a strongly asymmetric peak at a nonzero frequency. The shape of the peak is restored from the calculated 14 spectral moments, the asymptotic form of its high-frequency tail, and the scaling behavior of the conductivity for omega -> 0. We also calculate 10 spectral moments of the cyclotron resonance absorption peak and restore the corresponding (non-singular) frequency dependence using the continuous fraction expansion. Both expansions converge rapidly with increasing number of included moments, and give numerically accurate results throughout the region of interest. We discuss the possibility of experimental observation of the predicted effects for electrons on helium.Comment: RevTeX 3.0, 14 pages, 8 eps figures included with eps

    Magnetic trapping of ultracold neutrons

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    Three-dimensional magnetic confinement of neutrons is reported. Neutrons are loaded into an Ioffe-type superconducting magnetic trap through inelastic scattering of cold neutrons with 4He. Scattered neutrons with sufficiently low energy and in the appropriate spin state are confined by the magnetic field until they decay. The electron resulting from neutron decay produces scintillations in the liquid helium bath that results in a pulse of extreme ultraviolet light. This light is frequency downconverted to the visible and detected. Results are presented in which 500 +/- 155 neutrons are magnetically trapped in each loading cycle, consistent with theoretical predictions. The lifetime of the observed signal, 660 s +290/-170 s, is consistent with the neutron beta-decay lifetime.Comment: 17 pages, 18 figures, accepted for publication in Physical Review

    Pembrolizumab monotherapy for previously treated metastatic triple-negative breast cancer: cohort A of the phase II KEYNOTE-086 study

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    ABSTRACT Background Treatment options for previously treated metastatic triple-negative breast cancer (mTNBC) are limited. In cohort A of the phase II KEYNOTE-086 study, we evaluated pembrolizumab as second or later line of treatment for patients with mTNBC. Patients and methods Eligible patients had centrally confirmed mTNBC, ≥1 systemic therapy for metastatic disease, prior treatment with anthracycline and taxane in any disease setting, and progression on or after the most recent therapy. Patients received pembrolizumab 200 mg intravenously every 3 weeks for up to 2 years. Primary end points were objective response rate in the total and PD-L1–positive populations, and safety. Secondary end points included duration of response, disease control rate (percentage of patients with complete or partial response or stable disease for ≥24 weeks), progression-free survival, and overall survival. Results All enrolled patients (N = 170) were women, 61.8% had PD-L1–positive tumors, and 43.5% had received ≥3 previous lines of therapy for metastatic disease. ORR (95% CI) was 5.3% (2.7–9.9) in the total and 5.7% (2.4–12.2) in the PD-L1–positive populations. Disease control rate (95% CI) was 7.6% (4.4–12.7) and 9.5% (5.1–16.8), respectively. Median duration of response was not reached in the total (range, 1.2+–21.5+) and in the PD-L1–positive (range, 6.3–21.5+) populations. Median PFS was 2.0 months (95% CI, 1.9–2.0), and the 6-month rate was 14.9%. Median OS was 9.0 months (95% CI, 7.6–11.2), and the 6-month rate was 69.1%. Treatment-related adverse events occurred in 103 (60.6%) patients, including 22 (12.9%) with grade 3 or 4 AEs. There were no deaths due to AEs. Conclusions Pembrolizumab monotherapy demonstrated durable antitumor activity in a subset of patients with previously treated mTNBC and had a manageable safety profile. Clinical trial registration ClinicalTrials.gov, NCT0244700

    Quest for Localized 4-D Black Holes in Brane Worlds

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    We investigate the possibility of obtaining localized black hole solutions in brane worlds by introducing a dependence of the four-dimensional line--element on the extra dimension. An analysis, performed for the cases of an empty bulk and of a bulk containing either a scalar or a gauge field, reveals that no conventional type of matter can support such a dependence. Considering a particular ansatz for the five-dimensional line--element that corresponds to a black hole solution with a ``decaying'' horizon, we determine the bulk energy--momentum tensor capable of sustaining such a behaviour. It turns out that an exotic, shell-like distribution of matter is required. For such solutions, the black hole singularity is indeed localized near the brane and the spacetime is well defined near the AdS horizon, in contrast to the behaviour found in black string type solutions.Comment: 17 pages, RevTex, 3 figures, version to appear in Physical Review D, comments and references added, typos correcte

    Experimental and Theoretical Challenges in the Search for the Quark Gluon Plasma: The STAR Collaboration's Critical Assessment of the Evidence from RHIC Collisions

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    We review the most important experimental results from the first three years of nucleus-nucleus collision studies at RHIC, with emphasis on results from the STAR experiment, and we assess their interpretation and comparison to theory. The theory-experiment comparison suggests that central Au+Au collisions at RHIC produce dense, rapidly thermalizing matter characterized by: (1) initial energy densities above the critical values predicted by lattice QCD for establishment of a Quark-Gluon Plasma (QGP); (2) nearly ideal fluid flow, marked by constituent interactions of very short mean free path, established most probably at a stage preceding hadron formation; and (3) opacity to jets. Many of the observations are consistent with models incorporating QGP formation in the early collision stages, and have not found ready explanation in a hadronic framework. However, the measurements themselves do not yet establish unequivocal evidence for a transition to this new form of matter. The theoretical treatment of the collision evolution, despite impressive successes, invokes a suite of distinct models, degrees of freedom and assumptions of as yet unknown quantitative consequence. We pose a set of important open questions, and suggest additional measurements, at least some of which should be addressed in order to establish a compelling basis to conclude definitively that thermalized, deconfined quark-gluon matter has been produced at RHIC.Comment: 101 pages, 37 figures; revised version to Nucl. Phys.

    Resummation of the Divergent Perturbation Series for a Hydrogen Atom in an Electric Field

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    We consider the resummation of the perturbation series describing the energy displacement of a hydrogenic bound state in an electric field (known as the Stark effect or the LoSurdo-Stark effect), which constitutes a divergent formal power series in the electric field strength. The perturbation series exhibits a rich singularity structure in the Borel plane. Resummation methods are presented which appear to lead to consistent results even in problematic cases where isolated singularities or branch cuts are present on the positive and negative real axis in the Borel plane. Two resummation prescriptions are compared: (i) a variant of the Borel-Pade resummation method, with an additional improvement due to utilization of the leading renormalon poles (for a comprehensive discussion of renormalons see [M. Beneke, Phys. Rep. vol. 317, p. 1 (1999)]), and (ii) a contour-improved combination of the Borel method with an analytic continuation by conformal mapping, and Pade approximations in the conformal variable. The singularity structure in the case of the LoSurdo-Stark effect in the complex Borel plane is shown to be similar to (divergent) perturbative expansions in quantum chromodynamics.Comment: 14 pages, RevTeX, 3 tables, 1 figure; numerical accuracy of results enhanced; one section and one appendix added and some minor changes and additions; to appear in phys. rev.

    On the effects of the magnetic field and the isotopic substitution upon the infrared absorption of manganites

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    Employing a variational approach that takes into account electron-phonon and magnetic interactions in La1xAxMnO3La_{1-x}A_xMnO_3 perovskites with 0<x<0.50<x<0.5, the effects of the magnetic field and the oxygen isotope substitution on the phase diagram, the electron-phonon correlation function and the infrared absorption at x=0.3x=0.3 are studied. The lattice displacements show a strong correlation with the conductivity and the magnetic properties of the system. Then the conductivity spectra are characterized by a marked sensitivity to the external parameters near the phase boundary.Comment: 10 figure

    A narrative analysis of career transition themes and outcomes using chaos theory as a guiding metaphor

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    In a rapidly changing world of work little research exists on mid-career transitions. We investigated these using the open-systems approach of chaos theory as a guiding metaphor and conducted interviews with seven mid-career individuals chosen for their experience of a significant mid-career transition. Four common themes were identified through narrative analysis, where ‘false starts’ to a career were a common experience prior to finding a career ‘fit’. Career transitions, precipitated by a trigger state and/or event such as a period of disillusionment, were an important part of this ‘finding a fit’ process. Overall, career success outcomes were shaped by a combination of chaos elements: chance, unplanned events, and non-linearity of resultant outcomes. We discuss implications for future research and for practice
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