ACTUALIZACIÓN SOBRE EL USO DE MIEL EN EL TRATAMIENTO DE ÚLCERAS Y HERIDAS. CASO CLÍNICO.

In this articulate is made one revision sistematica of cientifica literature on the honey use in the treatment of hurt and ulceras. The honey has antibacterial and stimulating characteristics of the healing process. The high osmolaridad is partly responsible for its beneficial effects. When the honey is applied on a wound the glucose oxidasa locally produces hydrogen a slow peroxide liberation. Several comparative studies between honey of manuka and other types of honey have been made, and seems that the honey of manuka has a greater activity antibacterial. The honey has been used successfully in the treatment of hurt and burns. The pure honey without processing neither to sterilize has been used without no adverse reaction nor case some of botulism. The honey use can be an alternative to the traditional therapies, although it is needed to make great comparative studies between honey and other treatments. When being a natural, economic and present product in almost all the cultures, its use in the countries of the call third world could be very beneficial. The clinical case of a patient is exposed in whom pure honey in the treatment of several ulcers by pressure was used with good results.En este artículo se realiza una revisión sistemática de la literatura científica sobre el uso de miel en el tratamiento de úlceras y heridas. La miel tiene características antibacterianas y estimulantes del proceso de cicatrización. La osmolaridad alta es en parte responsable de sus efectos beneficiosos. Cuando la miel es aplicada sobre una herida la glucosa oxidasa produce localmente una liberación lenta de peróxido de hidrógeno. Se han realizado varios estudios comparativos entre miel de manuka y otros tipos de miel, y parece que la miel de manuka tiene una actividad antibacteriama mayor. La miel ha sido utilizada con éxito en el tratamiento de heridas y quemaduras. La miel pura sin procesar ni esterilizar ha sido utilizada sin ninguna reacción adversa ni caso alguno de botulismo. El uso de miel puede ser una alternativa a las terapias tradicionales, aunque se necesita realizar grandes estudios comparativos entre miel y otros tratamientos. Al tratarse de un producto natural, económico y presente en casi todas las culturas, su utilización en los países del llamado tercer mundo podría ser muy beneficiosa. Se expone el caso clínico de una paciente en la que se utilizó miel pura en el tratamiento de varias úlceras por presión (UPP) con buenos resultados

Reading-related Cognitive Deficits in Spanish Developmental Dyslexia

AbstractSpanish-speaking children learn to read words written in a relatively transparent orthography. Variations in orthographic transparency may shape the manifestation of reading difficulties. This study was intended to help clarify the nature of developmental dyslexia in Spanish. Developmentally Dyslexic children (DD) were compared to a chronological age-matched control group (CA). Measures included rapid automated naming, verbal working memory, phonological short-term memory, and phonemic awareness. Results demonstrated that developmental dyslexics show reading-related cognitive deficits in areas such as naming speed, verbal working memory, phonological short-term memory, and phonemic awareness. Our results are consistent with studies conducted in the Spanish language and in other transparent orthographies

Elastin-like-recombinamers multilayered nanofibrous scaffolds for cardiovascular applications

Producción CientíficaCoronary angioplasty is the most widely used technique for removing atherosclerotic plaques in blood vessels. The regeneration of the damaged intima layer after this treatment is still one of the major challenges in the field of cardiovascular tissue engineering. Different polymers have been used in scaffold manufacturing in order to improve tissue regeneration. Elastin-mimetic polymers are a new class of molecules that have been synthesized and used to obtain small diameter fibers with specific morphological characteristics. Elastin-like polymers produced by recombinant techniques and called elastin-like recombinamers (ELRs) are particularly promising due to their high degree of functionalization. Generally speaking, ELRs can show more complex molecular designs and a tighter control of their sequence than other chemically synthetized polymers Rodriguez Cabello et al (2009 Polymer 50 5159–69, 2011 Nanomedicine 6 111–22). For the fabrication of small diameter fibers, different ELRs were dissolved in 2,2,2-fluoroethanol (TFE). Dynamic light scattering was used to identify the transition temperature and get a deep characterization of the transition behavior of the recombinamers. In this work, we describe the use of electrospinning technique for the manufacturing of an elastic fibrous scaffold; the obtained fibers were characterized and their cytocompatibility was tested in vitro. A thorough study of the influence of voltage, flow rate and distance was carried out in order to determine the appropriate parameters to obtain fibrous mats without beads and defects. Moreover, using a rotating mandrel, we fabricated a tubular scaffold in which ELRs containing different cell adhesion sequences (mainly REDV and RGD) were collected. The stability of the scaffold was improved by using genipin as a crosslinking agent. Genipin-ELRs crosslinked scaffolds show a good stability and fiber morphology. Human umbilical vein endothelial cells were used to assess the in vitro bioactivity of the cell adhesion domains within the backbone of the ELRs.2018-08-0

Design rules for antenna placement on MIMO systems

In recent works, it is demonstrated that, depending on the different spatial distributions and distance between elements, there exists a different true polarization diversity (TPD) configuration that provides a high improvement in terms of capacity. This means that it is necessary to choose the appropriate TPD configuration to maximize the multiple-input-multiple-output (MIMO) capacity. In this work, a genetic algorithm is used to optimize the element positions for four new different configurations in combination with the TPD technique. It is shown that, for some configurations, the same polarization option is always found to reach the maximum capacity. Based on this, some novel design rules are provided to maximize MIMO capacity when the area for placing the antennas is very small. This is the case for most of the wireless devices, where the antenna design and location is one of the latest design constraints to be taken into consideration in the device design

On domain walls in a Ginzburg-Landau non-linear S^2-sigma model

The domain wall solutions of a Ginzburg-Landau non-linear $S^2$-sigma hybrid model are unveiled. There are three types of basic topological walls and two types of degenerate families of composite - one topological, the other non-topological- walls. The domain wall solutions are identified as the finite action trajectories (in infinite time) of a related mechanical system that is Hamilton-Jacobi separable in sphero-conical coordinates. The physical and mathematical features of these domain walls are thoroughly discussed.Comment: 26 pages, 18 figure

Mid- and Far-infrared Luminosity Functions and Galaxy Evolution from Multiwavelength Spitzer Observations up to z~2.5

[Abridged]We exploit a large homogeneous dataset to derive a self-consistent picture of IR emission based on the time-dependent 24, 15, 12 and 8micron monochromatic and bolometric IR luminosity functions (LF) over the 0<z<2.5 redshift range. Our analysis is based on the combination of data from deep Spitzer surveys in the VVDS-SWIRE and GOODS areas. To our limiting flux of S(24)=400microJy our derived sample in VVDS-SWIRE includes 1494 sources, and 666 and 904 sources brighter than S(24)=80microJy are catalogued in GOODS-S and GOODS-N, respectively, for a total area of ~0.9 square degs. We obtain reliable optical identifications and redshifts, providing us a rich and robust dataset for our luminosity function determination. Based on the multi-wavelength information available, we constrain the LFs at 8, 12, 15 and 24micron. We also extrapolate total IR luminosities from our best-fit to the observed SEDs of each source, and use this to derive the bolometric LF and comoving volume emissivity up to z~2.5. In the 0<z<1 interval, the bolometric IR luminosity density evolves as (1+z)^3.8+/-0.4. Although more uncertain at higher-z, our results show a flattening of the IR luminosity density at z>1. The mean redshift of the peak in the source number density shifts with luminosity: the brighest IR galaxies appear to be forming stars earlier in cosmic time (z>1.5), while the less luminous ones keep doing it at more recent epochs (z~1 for L(IR)<10^11L_sun). Our results suggest a rapid increase of the galaxy IR comoving volume emissivity back to z~1 and a constant average emissivity at z>1. We also seem to find a difference in the evolution rate of the source number densities as a function of luminosity, a downsizing evolutionary pattern similar to that reported from other samples of cosmic sources.Comment: Accepted for pubblicantion in Astronomy and Astrophysic

Buenas Prácticas en los Programas Universitarios para Mayores en España

Ana Isabel Muñoz Alcón y Francisco Trullén Galve (Universidad Catolica de Ávila); María P. García de la Torre y Francisco Ascón Belver (Universidad de A Coruña); M. Isabel Luis Rico, Ángel Gañán Adánez, Tamara de la Torre Cruz, Vanesa Baños Martínez (Universidad de Burgos); Yolanda Lázaro Fernández y Jaime Cuenca Amigo (Universidad de Deusto); Camino Caballero Posado (Universidad de Extremadura); Mª Adoración Holgado Sánchez y Mª Teresa Ramos Bernal (Universidad Pontificia de Salamanca); Sara Serrate González, Javier Alba Barrios y José Manuel Muñoz Rodríguez; Miguel Ángel Nombela Castaño (Universidad de Vigo

The [OIII] emission line luminosity function of optically selected type-2 AGN from zCOSMOS

We present a catalog of 213 type-2 AGN selected from the zCOSMOS survey. The selected sample covers a wide redshift range (0.15<z<0.92) and is deeper than any other previous study, encompassing the luminosity range 10^{5.5} < Lsun< L[OIII] < 10^{9.1} Lsun. We explore the intrinsic properties of these AGN and the relation to their X-ray emission (derived from the XMM-COSMOS observations). We study their evolution by computing the [OIII]5007A line luminosity function (LF) and we constrain the fraction of obscured AGN as a function of luminosity and redshift. The sample was selected on the basis of the optical emission line ratios, after applying a cut to the signal-to-noise ratio (S/N) of the relevant lines. We used the standard diagnostic diagrams [OIII]/Hbeta versus [NII]/Halpha and ([OIII]/Hbeta versus [SII]/Halpha) to isolate AGN in the redshift range 0.15<z<0.45 and the diagnostic diagram [OIII]/Hbeta versus [OII]/Hbeta to extend the selection to higher redshift (0.5<z<0.92). Combining our sample with one drawn from SDSS, we found that the best description of the evolution of type-2 AGN is a luminosity-dependent density evolution model. Moreover, using the type-1 AGN LF we were able to constrain the fraction of type-2 AGN to the total (type-1 + type-2) AGN population. We found that the type-2 fraction decreases with luminosity, in agreement with the most recent results, and shows signs of a slight increase with redshift. However, the trend with luminosity is visible only after combining the SDSS+zCOSMOS samples. From the COSMOS data points alone, the type-2 fraction seems to be quite constant with luminosity.Comment: 20 pages, 11 figures, accepted for publication in Astronomy and Astrophysic