Diarrhoea scores and weight changes in response to artificial milk supplementation or use of solulyte-neomycin solution in preweaning piglets

The objective of this study was to determine the effects of supplemental milk replacer and solulyte-neomix solution in preweaning piglets. A total of 199 five-day-old piglets from 22litters were available for this three-week study. 12 litters (110 piglets) were allocated into the milk replacer supplemented group (MILK), five litters (47 piglets) were allocated into the ELEC group which was given an antibiotic-fortified electrolyte solution for pigs, and five litters (45 piglets) remained as untreated control (CTRL). However, after matching for litter size and total litter weights among treatment groups, only 44 piglets (5litters) in the MILK group, 47 piglets (5 litters) in the ELEC group and 45 piglets from 5 litters in the CTRL group were considered in this report. All sows were fed the same diet (18 % protein, 3,952 kcal of ME/kg). Body weights of piglets were measured at days 5 and 25 of age. Fresh liquid commercial milk replacer and solulyte-neomix solution were prepared daily. The fluids were offered thrice daily at 100mL per litter for 5-day-old piglets. Supplementation was increased to 5 times daily at 200mL per litter when piglets were 9 days or older, till the end of the trial. Average litter weight gain was higher in the ELEC piglets given solulyte-neomix solution and creep feed (P<0.05). Milk replacer supplemented group (MILK) generally had lower average litter weight gains at 3.72 kg. However, the diarrhea scores were affected by the types of supplementation fluids given. The overall diarrhoea scores were higher in the MILK and CTRL piglets compared to the ELEC piglets. In conclusion, milk replacer supplementation offered no obvious benefit in terms of weight gain, final weight, and overall diarrhoea scores in piglets compared to solulyte-neomix supplemented piglets

Nonlinear optics and optical limiting properties of multifunctional fullerenol/polymer composite

The nonlinear optics and optical limiting properties of materials based on multifunctional fullerenol and poly(styrene-co-4-vinylpyridine) matrix were studied using 7 ns pulses of nanosecond laser operating at 532 nm wavelength. The observed imaginary and real parts of third order susceptibility of the fullerenol/polymer composite are found to be lower than that of its parent C60. The optical limiting performances of fullerenol and fullerenol incorporated with poly(styrene-co-4-vinylpyridine) have been proved to be poorer than that of C60 due to their higher limiting thresholds. Concentration dependence of poly(styrene-co-4-vinylpyridine) containing 32 mol% has been mainly contributed to the optical limiting performance of fullerenol.Comment: 23 pages, 9 figures, presented in ISMOA-2002, Bandung, Indonesia. Submitted to J. Nonlinear Opt. Phys. (December 2002

Effects of biomaterials keratin-gelatin and basic fibroblast growth factor-gelatin composite film on wound healing in dogs

Eighteen clinically healthy dogs weighing 10-15 kg body weight were used in this study over a 20-day period. They were allocated randomly into 3 groups of 6 animals each. After the creation of 5 cm x 5cm open wound, Group I was control treated with Gentamycin ointment. Groups II and ill were treated with keratin-gelatin and basic fibroblast growth factor (bFGF)-gelatin composite film respectively. On application, the keratin-gelatin and bFGF-gelatin composite film were well accepted by the animals without any adverse reaction. On clinical examination, Group II showed bright beefy red color granulation tissue with angiogenesis when compared to Groups I and ill. On bacteriological examination, Staphylococcus aureus, Pseudomonas, Escherichia coli, Proteus and Klebsiella species were isolated from all the groups. Mean percentage of epithelialisation, wound contraction and total healing were significantly better in Group II (P<0.05). Keratin is a biocompatible protein which does not interfere with the body's normal immunologic response and therefore it can be used in extensive wounds and also in non healing chronic wounds which need a trigger to stimulate the normal healing process. In extensive wounds when there is lack of autologous tissue, biomaterials like keratin-gelatin may be beneficial and can be used

Loss minimization DTC electric motor drive system based on adaptive ANN strategy

Electric motor drive systems (EMDS) have been recognized as one of the most promising motor systems recently due to their low energy consumption and reduced emissions. With only some exceptions, EMDS are the main source for the provision of mechanical energy in industry and accounts for about 60% of global industrial electricity consumption. Large energy efficiency potentials have been identified in EMDS with very short payback time and high-cost effectiveness. Typical, during operation at rated mode, the motor drive able to hold its good efficiencies. However, a motor usually operates out from rated mode in many applications, especially while under light load, it reduced the motor’s efficiency severely. Hence, it is necessary that a conventional drive system to embed with loss minimization strategy to optimize the drive system efficiency over all operation range. Conventionally, the flux value is keeping constantly over the range of operation, where it should be highlighted that for any operating point, the losses could be minimize with the proper adjustment of the flux level to a suitable value at that point. Hence, with the intention to generate an adaptive flux level corresponding to any operating point, especially at light load condition, an online learning Artificial Neural Network (ANN) controller was proposed in this study, to minimize the system losses. The entire proposed strategic drive system would be verified under the MATLAB/Simulink software environment. It is expected that with the proposed online learning Artificial Neural Network controller efficiency optimization algorithm can achieve better energy saving compared with traditional blended strategies

Cardiovascular Outcomes in Acute Coronary Syndrome and Malnutrition: A Meta-Analysis of Nutritional Assessment Tools

Background: There is emerging evidence that malnutrition is associated with poor prognosis among patients with acute coronary syndrome (ACS). // Objectives: This study seeks to elucidate the prognostic impact of malnutrition in patients with ACS and provide a quantitative review of most commonly used nutritional assessment tools. // Methods: Medline and Embase were searched for studies reporting outcomes in patients with malnutrition and ACS. Nutritional screening tools of interest included the Prognostic Nutrition Index, Geriatric Nutritional Risk Index, and Controlling Nutritional Status. A comparative meta-analysis was used to estimate the risk of all-cause mortality and cardiovascular events based on the presence of malnutrition and stratified according to ACS type, ACS intervention, ethnicity, and income. // Results: Thirty studies comprising 37,303 patients with ACS were included, of whom 33.5% had malnutrition. In the population with malnutrition, the pooled mortality rate was 20.59% (95% CI: 14.95%-27.67%). Malnutrition was significantly associated with all-cause mortality risk after adjusting for confounders including age and left ventricular ejection fraction (adjusted HR: 2.66, 95% CI: 1.78-3.96, P = 0.004). There was excess mortality in the group with malnutrition regardless of ACS type (P = 0.132), ethnicity (P = 0.245), and income status (P = 0.058). Subgroup analysis demonstrated no statistically significant difference in mortality risk between individuals with and without malnutrition (P = 0.499) when using Controlling Nutritional Status (OR: 7.80, 95% CI: 2.17-28.07, P = 0.011), Geriatric Nutritional Risk Index (OR: 4.30, 95% CI: 2.78-6.66, P < 0.001), and Prognostic Nutrition Index (OR: 4.67, 95% CI: 2.38-9.17, P = 0.023). // Conclusions: Malnutrition was significantly associated with all-cause mortality risk following ACS, regardless of ACS type, ethnicity, and income status, underscoring the importance of screening and interventional strategies for patients with malnutrition

The changing seroepidemiology of enterovirus 71 infection among children and adolescents in Singapore

<p>Abstract</p> <p>Background</p> <p>Enterovirus 71 (EV71) has caused recurrent epidemics of hand, foot and mouth disease among children in Singapore. Between August 2008 and July 2010, we conducted a survey to estimate the seroprevalence of EV71 infection among children and adolescents aged 1-17 years. We compared our EV71 seroepidemiologic findings with a previous study conducted in 1996-1997.</p> <p>Methods</p> <p>The survey involved the prospective collection of 1,200 residual sera from Singapore residents aged 1-17 years in two hospitals. Neutralizing antibodies to EV71 were detected by the microneutralization test. The geometric mean titer (GMT) of EV71 antibodies and 95% confidence intervals (CI) were calculated and compared by age groups. Statistical significance was taken as <it>P </it>< 0.05.</p> <p>Results</p> <p>The overall EV71 antibody prevalence was 26.9% (95% CI: 24.5-29.5%). It increased significantly from 14.3% in children aged 1-6 years to 27.8% in those aged 7-12 years, and reached 38.8% in adolescents aged 13-17 years. The seroconversion rate differed by about 12% between the consecutive age groups. The GMT of EV71 antibodies was higher among primary school children aged 7-12 years in our study than that among the 6-12 year age group in the 1996-1997 study.</p> <p>Conclusions</p> <p>Higher antibody titers were observed in children aged 1-6 years than those in the other two age groups, indicating that most of the infections had been acquired during early childhood. EV71 infection is common among children and adolescents in Singapore, with 39% infected by the time they are in secondary school (13-17 years of age).</p

Seroepidemiology of coxsackievirus A6, coxsackievirus A16, and Enterovirus 71 infections among children and adolescents in Singapore, 2008-2010

10.1371/journal.pone.0127999PLoS ONE105e012799

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Measurement of the Z/gamma* + b-jet cross section in pp collisions at 7 TeV

The production of b jets in association with a Z/gamma* boson is studied using proton-proton collisions delivered by the LHC at a centre-of-mass energy of 7 TeV and recorded by the CMS detector. The inclusive cross section for Z/gamma* + b-jet production is measured in a sample corresponding to an integrated luminosity of 2.2 inverse femtobarns. The Z/gamma* + b-jet cross section with Z/gamma* to ll (where ll = ee or mu mu) for events with the invariant mass 60 < M(ll) < 120 GeV, at least one b jet at the hadron level with pT > 25 GeV and abs(eta) < 2.1, and a separation between the leptons and the jets of Delta R > 0.5 is found to be 5.84 +/- 0.08 (stat.) +/- 0.72 (syst.) +(0.25)/-(0.55) (theory) pb. The kinematic properties of the events are also studied and found to be in agreement with the predictions made by the MadGraph event generator with the parton shower and the hadronisation performed by PYTHIA.Comment: Submitted to the Journal of High Energy Physic