144 research outputs found
Potential core species and satellite species in the bacterial community within the rabbit caecum
A bacteria library was constructed from the caecum of a rabbit maintained under standard conditions. The complete gene 16S rRNA gene was sequenced. The 228 clones obtained were distributed in 70 operational taxonomic units (OTUs). The large majority of the OTUs were composed of one or two clones and seven OTUs contained half of the sequences. Fourteen sequences had high similarity to the sequence already registered in databases (threshold of 97%). Only one of these sequences has been identified as Variovorax sp. (99% identity). Units were distributed mainly (94%) in the Firmicutes phylum. Three sequences were related to Bacteroidetes. Nine clusters were defined in the phylogenic tree. A great diversity of caecal bacteria of the rabbit was shown. Half of the sequences generated in this library were distributed in the phylogenetic tree near the sequences characterized previously in rabbit caecum (potential core species), and the other half of the sequences were well separated (satellite species)
Les fouilles de Tepecik-Çiftlik et les activités du programme Melendiz préhistorique, campagne 2016
Tepecik-Çiftlik est un site d’habitat de la fin de la Préhistoire, couvrant une période allant de la fin du Néolithique PPNB (ou Acéramique selon les définitions régionales) jusqu’au Chalcolithique Ancien, soit de quelques 8000 à 6000 BC cal. Localisé en Turquie, sur le plateau anatolien (Fig. 1), il se situe dans la plaine de la Melendiz, au Sud de la Cappadoce (province de Niğde). C’est en 2000 que le site fut mis en fouille par le département de Préhistoire de l’Université d’Istanbul, sous..
On the accumulation of planetesimals near disc gaps created by protoplanets
We have performed three-dimensional two-fluid (gas-dust) hydrodynamical
models of circumstellar discs with embedded protoplanets (3 - 333 M\oplu) and
small solid bodies (radii 10cm to 10m). We find that high mass planets (\gtrsim
Saturn mass) open sufficiently deep gaps in the gas disc such that the density
maximum at the outer edge of the gap can very efficiently trap metre-sized
solid bodies. This allows the accumulation of solids at the outer edge of the
gap as solids from large radii spiral inwards to the trapping region. This
process of accumulation occurs fastest for those bodies that spiral inwards
most rapidly, typically metre-sized boulders, whilst smaller and larger objects
will not migrate sufficiently rapidly in the discs lifetime to benefit from the
process. Around a Jupiter mass planet we find that bound clumps of solid
material, as large as several Earth masses, may form, potentially collapsing
under self-gravity to form planets or planetesimals. These results are in
agreement with Lyra et al. (2009), supporting their finding that the formation
of a second generation of planetesimals or of terrestrial mass planets may be
triggered by the presence of a high mass planet.Comment: 14 pages, 10 figures. Accepted for publication in MNRA
Asteroids' physical models from combined dense and sparse photometry and scaling of the YORP effect by the observed obliquity distribution
The larger number of models of asteroid shapes and their rotational states
derived by the lightcurve inversion give us better insight into both the nature
of individual objects and the whole asteroid population. With a larger
statistical sample we can study the physical properties of asteroid
populations, such as main-belt asteroids or individual asteroid families, in
more detail. Shape models can also be used in combination with other types of
observational data (IR, adaptive optics images, stellar occultations), e.g., to
determine sizes and thermal properties. We use all available photometric data
of asteroids to derive their physical models by the lightcurve inversion method
and compare the observed pole latitude distributions of all asteroids with
known convex shape models with the simulated pole latitude distributions. We
used classical dense photometric lightcurves from several sources and
sparse-in-time photometry from the U.S. Naval Observatory in Flagstaff,
Catalina Sky Survey, and La Palma surveys (IAU codes 689, 703, 950) in the
lightcurve inversion method to determine asteroid convex models and their
rotational states. We also extended a simple dynamical model for the spin
evolution of asteroids used in our previous paper. We present 119 new asteroid
models derived from combined dense and sparse-in-time photometry. We discuss
the reliability of asteroid shape models derived only from Catalina Sky Survey
data (IAU code 703) and present 20 such models. By using different values for a
scaling parameter cYORP (corresponds to the magnitude of the YORP momentum) in
the dynamical model for the spin evolution and by comparing synthetics and
observed pole-latitude distributions, we were able to constrain the typical
values of the cYORP parameter as between 0.05 and 0.6.Comment: Accepted for publication in A&A, January 15, 201
IP Pegasi: Investigation of the accretion disk structure. Searching evidences for spiral shocks in the quiescent accretion disk
We present the results of spectral investigations of the cataclysmic variable
IP Peg in quiescence. Optical spectra obtained on the 6-m telescope at the
Special Astrophysical Observatory (Russia), and on the 3.5-m telescope at the
German-Spanish Astronomical Center (Calar Alto, Spain), have been analysed by
means of Doppler tomography and Phase Modelling Technique. From this analysis
we conclude that the quiescent accretion disk of IP Peg has a complex
structure. There are also explicit indications of spiral shocks. The Doppler
maps and the variations of the peak separation of the emission lines confirm
this interpretation. We have detected that all the emission lines show a rather
considerable asymmetry of their wings varying with time. The wing asymmetry
shows quasi-periodic modulations with a period much shorter than the orbital
one. This indicates the presence of an emission source in the binary rotating
asynchronously with the binary system. We also have found that the brightness
of the bright spot changes considerably during one orbital period. The spot
becomes brightest at an inferior conjunction, whereas it is almost invisible
when it is located on the distant half of the accretion disk. Probably, this
phenomenon is due to an anisotropic radiation of the bright spot and an eclipse
of the bright spot by the outer edge of the accretion disk.Comment: 13 pages, 11 figures (= 21 EPS files), accepted for publication in
A&
Galex and optical observations of GW librae during the long decline from superoutburst
The prototype of accreting, pulsating white dwarfs (GW Lib) underwent a large amplitude dwarf nova outburst in 2007. We used ultraviolet data from Galaxy Evolution Explorer and ground-based optical photometry and spectroscopy to follow GW Lib for three years following this outburst. Several variations are apparent during this interval. The optical shows a superhump modulation in the months following outburst, while a 19 minute quasi-periodic modulation lasting for several months is apparent in the year after outburst. A long timescale (about 4 hr) modulation first appears in the UV a year after outburst and increases in amplitude in the following years. This variation also appears in the optical two years after outburst but is not in phase with the UV. The pre-outburst pulsations are not yet visible after three years, likely indicating the white dwarf has not returned to its quiescent state
Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib
Upon DNA binding the poly(ADP-ribose) polymerase family of enzymes (PARPs) add multiple ADP-ribose subunits to themselves and other acceptor proteins. Inhibitors of PARPs have become an exciting and real prospect for monotherapy and as sensitizers to ionising radiation (IR). The action of PARPs are reversed by poly(ADP-ribose) glycohydrolase (PARG). Until recently studies of PARG have been limited by the lack of an inhibitor. Here, a first in class, specific, and cell permeable PARG inhibitor, PDD00017273, is shown to radiosensitize. Further, PDD00017273 is compared with the PARP1/2/3 inhibitor olaparib. Both olaparib and PDD00017273 altered the repair of IR-induced DNA damage, resulting in delayed resolution of RAD51 foci compared with control cells. However, only PARG inhibition induced a rapid increase in IR-induced activation of PRKDC (DNA-PK) and perturbed mitotic progression. This suggests that PARG has additional functions in the cell compared with inhibition of PARP1/2/3, likely via reversal of tankyrase activity and/or that inhibiting the removal of poly(ADP-ribose) (PAR) has a different consequence to inhibiting PAR addition. Overall, our data are consistent with previous genetic findings, reveal new insights into the function of PAR metabolism following IR and demonstrate for the first time the therapeutic potential of PARG inhibitors as radiosensitizing agents
Study of the diversity of culturable actinomycetes in the North Pacific and Caribbean coasts of Costa Rica
In this study, 137 actinomycetes were isolated from subtidal marine sediments in the North Pacific and Caribbean coasts of Costa Rica. Bioinformatics analysis of the 16S rRNA gene sequences assigned the isolates to 15 families and 21 genera. Streptomyces was the dominant genus while the remaining 20 genera were poorly represented. Nearly 70% of the phylotypes presented a coastal-restricted distribution whereas the other 30% were common inhabitants of both shores. The coastal tropical waters of Costa Rica showed a high diversity of actinomycetes, both in terms of the number of species and phylogenetic composition, although significant differences were observed between and within shores. The observed pattern of species distribution might be the result of several factors including the characteristics of the ecosystems, presence of endemic species and the influence of terrestrial runoff.University of Aberdeen/[]//EscociaNational Institutes of Health/[U01 TW007404-01 ICBG]/NIH/Estados UnidosUCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de BiologíaUCR::Vicerrectoría de Docencia::Ciencias Básicas::Facultad de Ciencias::Escuela de Químic
Evidence of multiple halogen sources in scapolites from iron oxide-copper-gold (IOCG) deposits and regional Na Cl metasomatic alteration, Norrbotten County, Sweden
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