5,629 research outputs found
Observations of Chemically Enriched QSO Absorbers near z ~ 2.3 Galaxies: Galaxy-Formation Feedback Signatures in the IGM
We present a study of galaxies and intergalactic gas toward the z=2.73 quasar
HS1700+6416, to explore the effects of galaxy formation feedback on the IGM.
Our observations and ionization simulations indicate that the volume within
100-200 h_71^{-1} physical kpc of high-redshift galaxies contains very small,
dense, and metal-rich absorption-line regions. These systems often contain
shock-heated gas seen in OVI, and may exhibit [Si/C] abundance enhancements
suggestive of Type II supernova enrichment. We argue that the absorbers
resemble thin sheets or bubbles, whose physical properties can be explained
with a simple model of radiatively efficient shocks propegating through the
IGM. Their high metallicities suggest that these shocks are being expelled
from--rather than falling into--star forming galaxies. There is a dropoff in
the IGM gas density at galaxy impact parameters beyond ~300 physical kpc that
may trace boundaries of gas structures where the galaxies reside. The local
heavy-element enhancement covers 100-200 kpc; beyond this the observed
abundances blend into the general IGM. Supernova-driven winds or dynamical
stripping of interstellar gas appears to affect the IGM near massive galaxies,
even at R>~100 kpc. However, these feedback systems represent only a few
percent of the Lya forest mass at z~2.5. Their mass could be larger if the more
numerous metal-poor CIV systems at >~200 kpc are tepid remnants of very
powerful winds. Based on present observations it is not clear that this
scenario is to be favored over one involving pre-enrichment by smaller galaxies
at z>~6.Comment: Accepted for publication in the Astrophysical Journal. 26 pages
emulateapj, incl. 5 pages tables, 15 figure
Strong cloud–circulation coupling explains weak trade cumulus feedback
Shallow cumulus clouds in the trade-wind regions cool the planet by reflecting solar radiation. The response of trade cumulus clouds to climate change is a key uncertainty in climate projections. Trade cumulus feedbacks in climate models are governed by changes in cloud fraction near cloud base with high-climate-sensitivity models suggesting a strong decrease in cloud-base cloudiness owing to increased lower-tropospheric mixing. Here we show that new observations from the EUREC4A (Elucidating the role of cloud-circulation coupling in climate) field campaign refute this mixing-desiccation hypothesis. We find the dynamical increase of cloudiness through mixing to overwhelm the thermodynamic control through humidity. Because mesoscale motions and the entrainment rate contribute equally to variability in mixing but have opposing effects on humidity, mixing does not desiccate clouds. The magnitude, variability and coupling of mixing and cloudiness differ markedly among climate models and with the EUREC4A observations. Models with large trade cumulus feedbacks tend to exaggerate the dependence of cloudiness on relative humidity as opposed to mixing and also exaggerate variability in cloudiness. Our observational analyses render models with large positive feedbacks implausible and both support and explain at the process scale a weak trade cumulus feedback. Our findings thus refute an important line of evidence for a high climate sensitivit
Nuclear Physics Neutrino PreTown Meeting: Summary and Recommendations
In preparation for the nuclear physics Long Range Plan exercise, a group of
104 neutrino physicists met in Seattle September 21-23 to discuss both the
present state of the field and the new opportunities of the next decade. This
report summarizes the conclusions of that meeting and presents its
recommendations. Further information is available at the workshop's web site.
This report will be further reviewed at the upcoming Oakland Town Meeting.Comment: Latex, 31 pages. This version has been updated to include final
Comments from the working group
Radiative rotational lifetimes and state-resolved relative detachment cross sections from photodetachment thermometry of molecular anions in a cryogenic storage ring
Photodetachment thermometry on a beam of OH in a cryogenic storage ring
cooled to below 10 K is carried out using two-dimensional, frequency and time
dependent photodetachment spectroscopy over 20 minutes of ion storage. In
equilibrium with the low-level blackbody field, we find an effective radiative
temperature near 15 K with about 90% of all ions in the rotational ground
state. We measure the J = 1 natural lifetime (about 193 s) and determine the
OH rotational transition dipole moment with 1.5% uncertainty. We also
measure rotationally dependent relative near-threshold photodetachment cross
sections for photodetachment thermometry.Comment: Manuscript LaTeX with 5 pages, 3 figures, and 1 table plus LaTeX
supplement with 12 pages, 3 figures and 3 tables. This article has been
accepted by Physical Review Letter
The Radial Distribution of the Interstellar Medium in Disk Galaxies: Evidence for Secular Evolution
One possible way for spiral galaxies to internally evolve would be for gas to flow to the center and form stars in a central disk (pseudo-bulge). If the inflow rate is faster than the rate of star formation, a central concentration of gas will form. In this paper we present radial profiles of stellar and 8 μm emission from polycyclic aromatic hydrocarbons (PAHs) for 11 spiral galaxies to investigate whether the interstellar medium in these galaxies contains a central concentration above that expected from the exponential disk. In general, we find that the two-dimensional CO and PAH emission morphologies are similar, and that they exhibit similar radial profiles. We find that in 6 of the 11 galaxies there is a central excess in the 8 μm and CO emission above the inward extrapolation of an exponential disk. In particular, all four barred galaxies in the sample have strong central excesses in both 8 μm and CO emission. These correlations suggest that the excess seen in the CO profiles is, in general, not simply due to a radial increase in the CO emissivity. In the inner disk, the ratio of the stellar to the 8 μm radial surface brightness is similar for 9 of the 11 galaxies, suggesting a physical connection between the average stellar surface brightness and the average gas surface brightness at a given radius. We also find that the ratio of the CO to 8 μm PAH surface brightness is consistent over the sample, implying that the 8 μm PAH surface brightness can be used as an approximate tracer of the interstellar medium
Selection and phenotypic characterization of a core collection of <i>Brachypodium distachyon</i> inbred lines
BACKGROUND: The model grass Brachypodium distachyon is increasingly used to study various aspects of grass biology. A large and genotypically diverse collection of B. distachyon germplasm has been assembled by the research community. The natural variation in this collection can serve as a powerful experimental tool for many areas of inquiry, including investigating biomass traits. RESULTS: We surveyed the phenotypic diversity in a large collection of inbred lines and then selected a core collection of lines for more detailed analysis with an emphasis on traits relevant to the use of grasses as biofuel and grain crops. Phenotypic characters examined included plant height, growth habit, stem density, flowering time, and seed weight. We also surveyed differences in cell wall composition using near infrared spectroscopy (NIR) and comprehensive microarray polymer profiling (CoMPP). In all cases, we observed extensive natural variation including a two-fold variation in stem density, four-fold variation in ferulic acid bound to hemicellulose, and 1.7-fold variation in seed mass. CONCLUSION: These characterizations can provide the criteria for selecting diverse lines for future investigations of the genetic basis of the observed phenotypic variation
Warm Molecular Gas in M51: Mapping the Excitation Temperature and Mass of H_2 with the Spitzer Infrared Spectrograph
We have mapped the warm molecular gas traced by the H_2 S(0) - H_2 S(5) pure
rotational mid-infrared emission lines over a radial strip across the nucleus
and disk of M51 (NGC 5194) using the Infrared Spectrograph (IRS) on the Spitzer
Space Telescope. The six H_2 lines have markedly different emission
distributions. We obtained the H_2 temperature and surface density
distributions by assuming a two temperature model: a warm (T = 100 - 300 K)
phase traced by the low J (S(0) - S(2)) lines and a hot phase (T = 400 - 1000
K) traced by the high J (S(2) - S(5)) lines. The lowest molecular gas
temperatures are found within the spiral arms (T ~ 155 K), while the highest
temperatures are found in the inter-arm regions (T > 700 K). The warm gas
surface density reaches a maximum of 11 M_sun/pc^2 in the northwestern spiral
arm, whereas the hot gas surface density peaks at 0.24 M_sun/pc^2 at the
nucleus. The spatial offset between the peaks in the warm and hot phases and
the differences in the distributions of the H_2 line emission suggest that the
warm phase is mostly produced by UV photons in star forming regions while the
hot phase is mostly produced by shocks or X-rays associated with nuclear
activity. The warm H_2 is found in the dust lanes of M51, spatially offset from
the brightest HII regions. The warm H_2 is generally spatially coincident with
the cold molecular gas traced by CO (J = 1 - 0) emission, consistent with
excitation of the warm phase in dense photodissociation regions (PDRs). In
contrast, the hot H_2 is most prominent in the nuclear region. Here, over a 0.5
kpc radius around the nucleus of M51, the hot H_2 coincides with [O IV](25.89
micron) and X-ray emission indicating that shocks and/or X-rays are responsible
for exciting this phase
Back to the future of soil metagenomics
JN was funded by a fellowship from the French MENESR.Peer reviewedPeer Reviewe
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Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions
A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone. Since the underlying mechanism is not known, we have investigated the effect of mycolactone on endothelial cells, focussing on the expression of surface anticoagulant molecules involved in the protein C anticoagulant pathway. Congenital deficiencies in this natural anticoagulant pathway are known to induce thrombotic complications such as purpura fulimans and spontaneous necrosis. Mycolactone profoundly decreased thrombomodulin (TM) expression on the surface of human dermal microvascular endothelial cells (HDMVEC) at doses as low as 2ng/ml and as early as 8hrs after exposure. TM activates protein C by altering thrombin's substrate specificity, and exposure of HDMVEC to mycolactone for 24 hours resulted in an almost complete loss of the cells' ability to produce activated protein C. Loss of TM was shown to be due to a previously described mechanism involving mycolactone-dependent blockade of Sec61 translocation that results in proteasome-dependent degradation of newly synthesised ER-transiting proteins. Indeed, depletion from cells determined by live-cell imaging of cells stably expressing a recombinant TM-GFP fusion protein occurred at the known turnover rate. In order to determine the relevance of these findings to BU disease, immunohistochemistry of punch biopsies from 40 BU lesions (31 ulcers, nine plaques) was performed. TM abundance was profoundly reduced in the subcutis of 78% of biopsies. Furthermore, it was confirmed that fibrin deposition is a common feature of BU lesions, particularly in the necrotic areas. These findings indicate that there is decreased ability to control thrombin generation in BU skin. Mycolactone's effects on normal endothelial cell function, including its ability to activate the protein C anticoagulant pathway are strongly associated with this. Fibrin-driven tisischemia could contribute to the development of the tissue necrosis seen in BU lesions
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