Implementation of an Optimization and Simulation-Based Approach for Detecting and Resolving Conflicts at Airport

International audienceIn this paper is presented a methodology that uses simulation together with optimization techniques for a conflict detection and resolution at airports. This approach provides more robust solutions to operative problems, since, optimization allows to come up with optimal or suboptimal solutions, on the other hand, simulation allows to take into account other aspects as stochasticity and interactions inside the system. Both the airport airspace (terminal manoeuvring area), and airside (runway taxiways and terminals), were modelled. In this framework, different restrictions such as speed, separation minima between aircraft, and capacity of airside components were taken into account. The airspace was modeled as a network of links and nodes representing the different routes, while the airside was modeled in a low detail, where runway, taxiways and terminals were modeled as servers with a specific capacity. The objective of this work is to detect and resolve conflicts both in the airspace and in the airside and have a balanced traffic load on the ground

Can neutron electromagnetic form factors be obtained by polarized inclusive electron scattering off polarized three-nucleon bound states?

The investigation of the electromagnetic inclusive responses of polarized $^{3}$He within the plane wave impulse approximation is briefly reported. A particular emphasys is put on the extraction, from the inclusive responses at the quasielastic peak, of the neutron form factors from feasible experiments.Comment: 6 pages, Latex, 4 Postscript figures. Presented to XVth Conference on "Few-body problems in Physics", Groningen July 1997.To appear in Nucl. Phys.

Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders

Validating the potential pathogenicity of copy number variants (CNVs) identified in genome-wide studies of autism spectrum disorders (ASD) requires detailed assessment of case/control frequencies, inheritance patterns, clinical correlations, and functional impact. Here, we characterize a small recurrent duplication in the annexin A1 (ANXA1) gene, identified by the Autism Genome Project (AGP) study

Portable smartphone quantitation of prostate specific antigen (PSA) in a fluoropolymer microfluidic device

We present a new, power-free and flexible detection system named MCFphone for portable colorimetric and fluorescence quantitative sandwich immunoassay detection of prostate specific antigen (PSA). The MCFphone is composed by a smartphone integrated with a magnifying lens, a simple light source and a miniaturised immunoassay platform, the Microcapillary Film (MCF). The excellent transparency and flat geometry of fluoropolymer MCF allowed quantitation of PSA in the range 0.9 to 60 ng/ml with < 7 % precision in 13 minutes using enzymatic amplification and a chromogenic substrate. The lower limit of detection was further improved from 0.4 to 0.08 ng/ml in whole blood samples with the use of a fluorescence substrate. The MCFphone has shown capable of performing rapid (13 to 22 minutes total assay time) colorimetric quantitative and highly sensitive fluorescence tests with good %Recovery, which represents a major step in the integration of a new generation of inexpensive and portable microfluidic devices with commercial immunoassay reagents and off-the-shelf smartphone technology

The effects of Gliricidia-derived biochar on sequential maize and bean farming

The addition of biochar to soils can improve soil fertility and increase agricultural productivity. We carried out a field experiment in which biochar produced from Gliricidia sepium (Jacq.) Kunth ex Walp. was added to low-fertility Brazilian planosol and tested to increase the yield of maize (Zea mays) and snap beans (Phaseolus vulgaris L.) in sequential, organic cultivation. Biochar was applied at a 15 t/ha rate, combined or not with Azospirillum Brasiliense inoculation and organic fertilizer (Bokashi). The application of biochar resulted in an increase in soil pH and of the content of macronutrients such as phosphorus and potassium. Contrary to evidence from elsewhere, biochar had a limited effect on increasing maize yield. In the case of beans, when combined with fertilizer, biochar increased the production of beans pods and biomass, but the significant increase was observed only for inoculation. Beans are the principal component of Brazilian diet and increasing productivity of beans is of upmost importance for the poorest in Brazil, and in other tropical countries

Bulge growth through disk instabilities in high-redshift galaxies

The role of disk instabilities, such as bars and spiral arms, and the associated resonances, in growing bulges in the inner regions of disk galaxies have long been studied in the low-redshift nearby Universe. There it has long been probed observationally, in particular through peanut-shaped bulges. This secular growth of bulges in modern disk galaxies is driven by weak, non-axisymmetric instabilities: it mostly produces pseudo-bulges at slow rates and with long star-formation timescales. Disk instabilities at high redshift (z>1) in moderate-mass to massive galaxies (10^10 to a few 10^11 Msun of stars) are very different from those found in modern spiral galaxies. High-redshift disks are globally unstable and fragment into giant clumps containing 10^8-10^9 Msun of gas and stars each, which results in highly irregular galaxy morphologies. The clumps and other features associated to the violent instability drive disk evolution and bulge growth through various mechanisms, on short timescales. The giant clumps can migrate inward and coalesce into the bulge in a few 10^8 yr. The instability in the very turbulent media drives intense gas inflows toward the bulge and nuclear region. Thick disks and supermassive black holes can grow concurrently as a result of the violent instability. This chapter reviews the properties of high-redshift disk instabilities, the evolution of giant clumps and other features associated to the instability, and the resulting growth of bulges and associated sub-galactic components.Comment: 37 pages, 9 figures. Invited refereed review to appear in "Galactic Bulges", E. Laurikainen, D. Gadotti, R. Peletier (eds.), Springe

Expression profiling of Castanea genes during resistant and susceptible interactions with the Oomycete pathogen Phytophthora cinnamomi reveal possible mechanisms of immunity

The most dangerous pathogen affecting the production of chestnuts is Phytophthora cinnamomi a hemibiotrophic that causes root rot, also known as ink disease. Little information has been acquired in chestnut on the molecular defense strategies against this pathogen. The expression of eight candidate genes potentially involved in the defense to P. cinnamomi was quantified by digital PCR in Castanea genotypes showing different susceptibility to the pathogen. Seven of the eight candidate genes displayed differentially expressed levels depending on genotype and time-point after inoculation. Cast_Gnk2-like revealed to be the most expressed gene across all experiments and the one that best discriminates between susceptible and resistant genotypes. Our data suggest that the pre-formed defenses are crucial for the resistance of C. crenata to P. cinnamomi. A lower and delayed expression of the eight studied genes was found in the susceptible Castanea sativa, which may be related with the establishment and spread of the disease in this species. A working model integrating the obtained results is presentedinfo:eu-repo/semantics/publishedVersio