CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

Search for a massive resonance decaying into a Higgs boson and a W or Z boson in hadronic final states in proton-proton collisions at root s=8 TeV

Peer reviewe

Data for the s Process from n_TOF

International audienceA considerable amount of (n, $\gamma$ ) reactions has been studied, so far, at the neutron time-of-flight facility n_TOF at CERN. The experimental program aims at determining and improving cross sections for a number of isotopes relevant to s-process nucleosynthesis. A brief summary of some physical cases related to the s-process nucleosyntheis is presented in this work together with ongoing experiments and challenging future programs

7^{7} Be(n,p)7^{7} Li Cross Section Measurement for the Cosmological Lithium Problem at the n _\_ TOF Facility at CERN

International audienceOne of the most puzzling problems in Nuclear Astrophysics is the “Cosmological Lithium Problem”, i.e the discrepancy between the primordial abundance of$^{7}$ Li observed in metal poor halo stars (Asplund et al. in Astrophys J 644:229–259, 2006, [1]), and the one predicted by Big Bang Nucleosynthesis (BBN). One of the reactions that could have an impact on the problem is$^{7}$ Be(n,p)$^{7}$ Li. Despite of the importance of this reaction in BBN, the cross-section has never been directly measured at the energies of interest for BBN. Taking advantage of the innovative features of the second experimental area at the n $\_$ TOF facility at CERN (Sabate-Gilarte et al. in Eur Phys J A 53:210, 2017, [2], Weiss et al. in NIMA 799:90, 2015, [3]), an accurate measurement of$^{7}$ Be(n,p) cross section has been recently performed at n $\_$ TOF, with a pure$^{7}$ Be target produced by implantation of a$^{7}$ Be beam at ISOLDE. The mesurement started in April 2016 and lasted for two months. The experimental procedure, the setup used in the measurement and the results obtained so far will be here presented