Correlación cito histológica de tumores en el sistema nervioso central

A total of 88 biopsies of the central nervous system performed in this hospital during 2010 were reviewed; 36 patients underwent intraoperative diagnosis by the method of imprinting crushing or crashing with the aim of establishing the value of cytology for diagnosis of these tumors. A total of 29 true positive and six true negative were obtained, with one false positive and zero false negatives. The sensitivity of cytology was 100%, the specificity was 86%, the positive predictive value was 100%, the negative predictive value was 86% and the efficiency and accuracy was 97%. The factors that influenced the mistakes were analyzed and it was concluded that this study is a useful and rapid method for the diagnosis of these tumors.Se revisaron un total de 88 biopsias del sistema nervioso central realizadas en el Hospital Provincial Universitario “Arnaldo Milián Castro” durante el año 2010; a 36 se les realizó el diagnóstico transoperatorio por el método de la impronta por aplastamiento o crashing con el objetivo de establecer el valor de la citología para el diagnóstico de estos tumores. Se obtuvieron un total de 29 verdaderos positivos y seis verdaderos negativos, con un falso positivo y cero falsos negativos. La sensibilidad del método citológico fue de 100%; la especificidad de 86%, el valor predictivo positivo fue de 100%, el valor predictivo negativo de 86% y la eficiencia y la precisión de 97%. Se analizan los factores que incidieron en los errores cometidos y se concluye que este estudio es un método útil y rápido para el diagnóstico de estos tumores

Land reclamation and artificial islands: Walking the tightrope between development and conservation

Coastal developments worldwide have put entire shoreline ecosystems at risk. Recently, land reclamation has been extended to the construction of whole new islands; a phenomenon that is particularly common in Asia and the Middle East and is recognised as a global conservation issue. Using Penang Island, Malaysia as a case study, we illustrate the relationship between rapid population growth and the simultaneous increase in urbanisation, land reclamation and extent of artificial shorelines; and decrease in the quality and extent of natural coastal habitats. Our goal was to provide an up-to-date assessment of the state of coastal habitats around Penang, identify knowledge gaps and identify locations that may be potentially suitable for eco-engineering. Comparisons of historical and current topographic maps revealed that land formerly consisting of coastal swamp and forest, mangrove forests, sandy beaches, and rubber and oil plantations have been lost to large-scale land reclamation and urbanisation. Between 1960 and 2015, there were increases in urbanised area, reclaimed land, and artificial shoreline extent. The total extent of mangrove forests has remained relatively stable but this balance is characterised by significant losses on the east coast coupled with increases on the west coast. Coastal development on the island is still on-going with plans for the construction of five artificial islands and another two coastal reclamation projects are either underway or scheduled for the near future. If the plans for future land reclamations are fully realized, 32.3 km2 of the 321.8 km2 island (10%) will be reclaimed land and the associated negative effects on the island’s natural coastal habitats will be inevitable. This study highlights sections of the coast of Penang Island in need of effective monitoring, conservation and management and explores the possibility of incorporating ecological engineering into development projects, either prospectively or retrospectively, to create more environmentally-friendly urban environments and to promote educational, amenity and economic activities. With coastal development taking place on a global scale, opportunities to balance development needs with conservation strategies abound and should be integrated into present and subsequent projects to protect these coastal ecosystems for future generations

Epidemiologic Features and Control Measures during Monkeypox Outbreak, Spain, June 2022

During June 2022, Spain was one of the countries most affected worldwide by a multicountry monkeypox outbreak with chains of transmission without identified links to disease-endemic countries. We provide epidemiologic features of cases reported in Spain and the coordinated measures taken to respond to this outbreak.S

From Science to Evidence – How Biodiversity Indicators Can Be Used for Effective Marine Conservation Policy and Management

Indicators are effective tools for summarizing and communicating key aspects of ecosystem state and have a long record of use in marine pollution and fisheries management. The application of biodiversity indicators to assess the status of species, habitats, and functional diversity in marine conservation and policy, however, is still developing and multiple indicator roles and features are emerging. For example, some operational biodiversity indicators trigger management action when a threshold is reached, while others play an interpretive, or surveillance, role in informing management. Links between biodiversity indicators and the pressures affecting them are frequently unclear as links can be obscured by environmental change, data limitations, food web dynamics, or the cumulative effects of multiple pressures. In practice, the application of biodiversity indicators to meet marine conservation policy and management demands is developing rapidly in the management realm, with a lag before academic publication detailing indicator development. Making best use of biodiversity indicators depends on sharing and synthesizing cutting-edge knowledge and experience. Using lessons learned from the application of biodiversity indicators in policy and management from around the globe, we define the concept of ‘biodiversity indicators,’ explore barriers to their use and potential solutions, and outline strategies for their effective communication to decision-makers

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

IMPACTO DE VARIÁVEIS CONGNITIVAS E CONTEXTUAIS SOBRE O SUCESSO ACADÊMICO E O BEM ESTAR NA UNIVERSIDADE – QUE FAZER? QUE DEIXAR DE FAZER?

Este estudo parte de uma investigação longitudinal (2019-2022) mais ampla, vinculada ao Grupo Multidisciplinar de Pesquisa em Educação, Psicopedagogia e Psicologia Escolar, UFAM/CNPq, PROCAD/AMAZÔNIA-PPGEUFAM/UFPA/UFMT, Processo CAPES 8881.314288/2019-0, articula-se metodológica e teoricamente com interfaces entre a psicologia escolar, psicologia educacional, pedagogia do ensino superior e educação escolar. Atua no sentido de entender os efeitos de variáveis cognitivas e contextuais sobre o sucesso acadêmico e o bem estar na universidade. A metodologia para coleta de dados é a aplicação de caderno de instrumentos próprios com apoio do Googleodocs, a amostra atual é de n=1112 estudantes de diferentes países (Brasil, México, República Dominicana, Bolívia, Moçambique, Angola, Venezuela, Colômbia, Espanha e Portugal), do sexo masculino e feminino, idade entre 18 e 54 anos e de 51 universidades públicas e privadas que colaboram com a iniciativa. Os dados são analisados com auxílio do Excel e SPSS, de acordo com os interesses dos pesquisadores e objetivos da investigação. Os resultados atuais demonstram a importância da pesquisa sobre os temas abordados pela iniciativa considerando o impacto das variáveis estudadas sobre o rendimento acadêmico e bom estar tanto de estudantes como de docentes e técnicos no ensino superior. Foram identificadas diferenças de países, renda, etnia, gênero e renda. No caso dos docentes e técnicos verificamos evidências da exaustão feminina. Os resultados podem apoiar a administração geral e coordenação educativa e psicopedagógica universitária em sentido amplo, visando a melhoria dos indicadores de sucesso acadêmico e bem estar, por meio da proposição de novas políticas e gestão da educação superior. Palavras-chave: Pesquisa em educação, Ensino superior, Rendimento acadêmico, Bem estar. Políticas de gestão da educação superior. Educação comparada. &nbsp; IMPACT OF COGNITIVE AND CONTEXTUAL VARIABLES ABOUT ACADEMIC PERFORMANCE AND &nbsp;WELLBEING IN THE UNIVERSITY. Whato to do? Qhato not to do? &nbsp; Abstract: This study, part of a further longitudinal investigation (2019-2022), attached to a multidisciplinary group of Educational Research&nbsp; Scholar Psychotherapy and Psychology, UFAM/CNPq, PROCAD/AMAZONIA-PPGEUFAM/UFPA/UFMT, CAPES process 8881.314288/2019-0, it is articulated methodological and theoretically with interfaces between the scholar and educational psychology, upper and scholar education pedagogy. It acts in the direction of understanding 5he effects og cognitive and contextual variables about the academic achievement and wellness in the university. The methodology to data collection is the application of own instrument cards with the support of Googledocs, the actual sample is quantity of n=1112 students from 51 private and public universities of different countries (Brazil, Mexico, Dominican Republic, Bolivia, Mozambique, Angola, Venezuela, Colombia, Spain and Portugal), from both male and female genders, aging between 18 and 54 years-old. The data were analyzed with the support of software Excel and SPSS, according to the interests of researchers and investigation focus. The actual results show the importance of the research about the themes cited in the initiative considering the impacts of the studied variables over the academic performance and wellness of the students as the teachers and technicians from upper education. There were found differences between countries, income, ethnic and gender. In the cases of the teachers and technicians it was found evidences of female exhaustion. The results could support the general administration, educative and psychopedagogy coordination and in a wide range, looking forward the better successful academic indicators and wellness, through the proposition of new policies and management of upper education. Keywords: Educational Reserch, upper educatión, academic performance, wellness, upper educaciton mangement policies, compared education. &nbsp

Protection alone may not promote natural recovery of biogenic habitats of high biodiversity damaged by mobile fishing gears

The horse mussel Modiolus modiolus (L.) is a large marine bivalve that aggregates to create complex habitats of high biodiversity. As a keystone species, M. modiolus is of great importance for the functioning of marine benthic ecosystems, forming biogenic habitats used to designate Marine Protected Areas (MPAs). The present study investigates the condition of M. modiolus beds historically subjected to intense scallop fishing using mobile fishing gears. The study, conducted seven years after the introduction of legislation banning all forms of fishing, aimed to establish whether natural habitat recovery occurs after protection measures are put in place. Lower biodiversity and up to 80% decline in densities of M. modiolus were recorded across the current distributional range of the species in Strangford Lough, Northern Ireland. The decline in biodiversity in most areas surveyed was consistent with that observed in biogenic reefs impacted by mobile fishing gears elsewhere. Epifauna, including sponges, hydroids and tunicates, experienced the most substantial decline in biodiversity, with up to 64% fewer taxa recorded in 2010 compared with 2003. Higher variability in community composition and a shift towards faunal assemblages dominated by opportunistic infaunal species typical of softer substrata were also detected. Based on these observations we suggest that, for biogenic habitats, the designation of MPAs and the introduction of fishing bans alone may not be sufficient to reverse or halt the negative effects caused by past anthropogenic impacts. Direct intervention, including habitat restoration based on translocation of native keystone species, should be considered as part of management strategies for MPAs which host similar biogenic reef habitats where condition and natural recovery have been compromised

Community convergence and recruitment of keystone species as performance indicators of artificial reefs

An experimental artificial reefwas constructed in Strangford Lough, Northern Ireland as part of trials to regenerate damaged biogenic reefs formed by the horse mussel Modiolus modiolus. Experimental reef plots were constructed using Pecten maximus shell as cultch. Clumps of live adult M. modiolus were translocated from nearby natural reefs into cultchwith a high profile (elevated cultch), cultch with a lowprofile (flattened cultch), as well as directly into the seafloor. The aim of the study was to test the hypothesis that translocated mussel clumps would increase habitat complexity thus accelerating community succession and enhancing natural recruitment of M. modiolus spat. These effects were predicted to be greater on elevated cultch due to greater protection frompredators and increased accessibility to food resources. Within the artificial reef array the translocated clumps had a significant positive effect on recruitment compared to cultch without mussels with average densities of spat settled on the translocated M. modiolus clumps ranging from 100 to 200 individuals m-2 compared to 4 to 52 spat m-2 on cultch without mussels. Recruitment of M. modiolus spat was also significantly higher on translocated horse mussels when compared to natural reefs where densities of 8–36 spat m-2 were recorded.Reef elevation appeared to provide some degree of protection from predators but differences in translocated M. modiolus survival on the different elevation treatments were not significant. In total, 223 taxa were recorded 12 months after reef construction. The presence of translocated clumps ofM. modiolus was the main driver of the increases in faunal diversity and species abundance. Application of objective criteria to assess the performance of artificial reefs suggested that translocation of M. modiolus clumps alone achieved most of the restoration objectives. Consequently this pilot study demonstrates a straightforward and realistic intervention technique that could be used to kick start the regeneration and expansion of impacted mussel and similar biogenic reefs elsewhere