45 research outputs found
A Backtracking Search Algorithm for the Simultaneous Size, Shape and Topology Optimization of Trusses
- Author
- Achtziger W.
- Adeli H.
- Agarwal P
- Ahrari A.
- Balling R.J.
- Behrooz A.
- Bland J.A.
- Civicioglu P.
- Deb K.
- Degertekin S.O.
- Degertekin S.O.
- Dominguez A.
- Dorn W.C.
- Fadel Miguel L. F.
- Galante M.
- Goldberg D.E.
- Goncalves M. S.
- Grierson D.E.
- Hajela P.
- Hajela P.
- Hansen S.R.
- Hasançebi O.
- Hasançebi O.
- Jármai K.
- Kaveh A
- Kaveh A.
- Kaveh A.
- Kaveh A.
- Kaveh A.
- Kaveh A.
- Kazemzadeh Azad S.
- Kazemzadeh Azad S.
- Kazemzadeh Azad S.
- Kelesoglu O.
- Koide R. M.
- Kutyłowski R.
- Lee K.S.
- Li J-P.
- Lobato F.S.
- Lopez R. H.
- Lopez R.H.
- Luh G.C.
- Luh G.C.
- Martini K.
- Miguel L. F. F.
- Miguel L.F.F
- Miguel L.F.F.
- Pereira J. T.
- Rajan S. D.
- Rajeev S.
- Rojas J.E.
- Sadollaha A.
- Salajegheh E.
- Sherestha S.M.
- Soh C.K.
- Sonmez M.
- Souza R.R.
- Tang W.
- Tang. W. Tong. L.
- Torii A. J.
- Torii A.J.
- Wu C.Y.
- Wu S.J.
- Zhanga Y.
- Šilih S.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub M.
- A. Adam M.
- A. Nassar M.
- A. Nemer A.
- Aahlin E. K.
- Ab Rahim M. F.
- Abad Gurumeta A.
- Abad-Motos A.
- Abang Jamari D. Z. H.
- Abantanga F.
- Abarca S.
- Abazid E.
- Abbas A.
- Abbas K.
- Abbas M. M.
- Abbasy J.
- Abbosh A.
- Abd B.
- Abd Karim M. F. S.
- Abd Wahab H. H.
- Abdalei A.
- Abdalla Ahmed Elkamel A.
- Abdallah A.
- AbdAllah M. S. M.
- Abdel Malik A. B.
- Abdelhady Mousa H.
- Abdelhady S.
- Abdelhakim A.
- Abdelkader M.
- Abdelkawy S.
- Abdelkhalek M.
- Abdellatif E.
- Abdelmaksoud Tawakel N.
- Abdelmohsen N.
- Abdelmotaleb I.
- Abdelrazek A.
- Abdelsalam I.
- Abdelshakour M.
- Abdelwahed A. M.
- Abdou A.
- Abdou A. O.
- Abdou H.
- Abdul Aziz M. R.
- Abdul Aziz N.
- Abdulgawad Almogy M.
- Abdulla M. A.
- Abdullah M. T.
- Abdullahi L.
- Abdullayev S.
- Abed S.
- Abello D.
- Abiola O.
- Abo mahadi A.
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- Abou Chaar M. K.
- Abou El. soud M. R.
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- Abreu da Silva A.
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- Abu Jamie N.
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised
Global economic burden of unmet surgical need for appendicitis
- Author
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- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
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- Abbas M
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
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- Abaliksta T
- Abantanga F
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- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
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- Abdel-Kader SM
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- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
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- Amin J
- Amin J
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- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
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- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
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- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
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- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
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- Anwer W
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- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
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- Asele FA
- Ashour A
- Ashour A
- Ashour K
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- Ashton A
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- Assal A
- Assouto PA
- Asturia S
- Asumah H
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- Ata AAA
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- Atiyeh A
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- Attard M
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- Aung KP
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- Aviles S
- Avoka A
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- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
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- Badwi NM
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- Bahar S
- Baheeg M
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- Baillie K
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- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
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- Baldacchino M
- Balducci G
- Balila RMH
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- Balmaceda R
- Balmaceda R
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- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
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- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
- Barrios E
- Barros De Castro Segundo LC
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- Barry J
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- Bassit KA
- Basso SMM
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- Batt J
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- Beasley W
- Beaton C
- Bedada AG
- Bediako-Bowan A
- Behar N
- Beisa V
- Beisa V
- Bekhet AH
- Bekhet NM
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- Belkouchi A
- Belli A
- Bello B
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- Benevento A
- Benevento A
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- Bennai RM
- Benons N
- Bentounsi Z
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- Berti S
- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezerra Morais PA
- Bezzina M
- Bhang A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj IS
- Bhat S
- Bhatnagar A
- Bhattacharya S
- Bhopal KF
- Bhopal KF
- Bianco F
- Bigaran A
- Billy M
- Bin Adnan A
- Bin Hasnan M
- Bin Ismail MJ
- Bin Mahamood A
- Birindelli A
- Birring A
- Bisset C
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- Bjorklund I
- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
- Blencowe N
- Blencowe N
- Bliksoen M
- Blower E
- Bluelle R
- Blundell R
- Boakye-Yiadom K
- Boal M
- Bocchetti T
- Boddy A
- Bode C
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- Bondin J
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- Bondurri A
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- Bonney W
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- Borda-Luque G
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- Bortolasi L
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- Botes S
- Bottini C
- Botto N
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- Bratu R-M
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- Bray LD
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- Breitenstein S
- Breslin R
- Brincat SD
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- Brown J
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- Burns H
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- Cabala Chiong JA
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- Castro Mollo M
- Catani M
- Cautiero R
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- Cecilia T
- Celik S
- Cengiz TB
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Cengiz Y
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- Chabok A
- Chachulski W
- Chai C-A
- Chai FY
- Chambers A
- Chambers A
- Chan E
- Chan L
- Chan T-YK
- Chan XW
- Chan Z
- Chandrakumar C
- Chang K
- Chang KY-C
- Chapman A
- Chapman SJ
- Charles A
- Cheah AEZ
- Chen CY
- Chen KY
- Chen T-L
- Chenn R
- Cheong YJ
- Chetta N
- Cheung YHE
- Chew LS
- Chhabra S
- Chibuye C
- Chidambaram S
- Chiesa D
- Chilton G
- Chin PX
- Chin YR
- Chiu S
- Chiu S
- Chiu SMY
- Choi J
- Choi P
- Chong BFHK
- Chong CL
- Chong CL
- Chong CL
- Chong CS
- Chong H-Y
- Chong HY
- Choudhry A
- Chow CYN
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung KJ
- Chung S
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- Cirocchi R
- Ciubotaru C
- Claire R
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- Clegg-Lamptey J-N
- Clement KD
- Clements JM
- Clerico G
- Clifford C
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- Coasaca Huaraya R
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- Contreras Vergara AL
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- Costas-Chavarri A
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- Court E
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- Cullen F
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- Currow C
- Currow C
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- D'Amours S
- D'amours SK
- D'cruz R
- D'Souza MS
- D'Souza R
- Da Silva LA
- Dabboor M
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- Dablouk M
- Dablouk MO
- Dagoe E
- Dahy A
- Dainius E
- Dakubo J
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- Danelli P
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- Daniyan M
- Danys D
- Dao W
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- Dar M
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- Darweesh M
- Darwish AKZ
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- De Sousa AV
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- Decker E
- Dedekind B
- Dedey F
- Deichsel F
- Del Basso C
- del Pilar Paucar A
- Delforge X
- Dell A
- Dempster E
- Denakpo M
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar GH
- Dharamshi HA
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu I-B
- Dias S
- Diaz Vico T
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake TM
- Drake TM
- Drake TM
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Dwydar A
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- Ebidy MM
- Ebrahim OS
- Eduard P
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- Ekow M
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- El Dahab AA
- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
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- Fairfield C
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- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
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- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler AJ
- Fozard T
- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
- Gad MO
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaignard E
- Gaignard E
- Gaizauskas V
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
- Galvez CP
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
- Gan C
- Gan YY
- Gani MA
- Garaycochea O
- Garcia Bernardo C
- Garcia Florez LJ
- Garcia Septiem J
- Garcia Torres CP
- Garcia-Florez L
- Garland A
- Gash K
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- Gastaldi P
- Gasteratos K
- Gaujoux S
- Gavagna L
- Gbessi DG
- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
- Germanos S
- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
- Ghandora N
- Ghanem A
- Ghanem E
- Ghanem S
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- Ghazy AA
- Gheith A
- Ghetia M
- Ghetia M
- Ghonaim MA
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- Ghoneim O
- Giacci L
- Giardino FR
- Giavarini L
- Giglio MC
- Gilbert R
- Gilbert RW
- Giles J
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- Giraldo RSR
- Giuliani S
- Giuliani S
- Giuriato TF
- Gkiokas G
- Glasbey J
- Glasbey J
- Glasbey JC
- GlobalSurg Collaborative
- Glover TE
- Glover-Addy H
- Glynn M
- Gobin N
- Gobin N
- Goh CC
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- Goh W
- Gohar ME-SAM
- Gokani S
- Goldin E
- Golding D
- Gomaa A
- Gomah M
- Gonzales Montejo MS
- Gonzales Stuva JP
- Gonzalez M
- Goodstein M
- Gosling S
- Gosling SG
- Gouda A
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- Gouldthorpe C
- Gouvas N
- Gouws J
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- Gran M
- Grandinetti PP
- Grant A
- Grasset E
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- Grassi V
- Gratton R
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- Gray D
- Grech N
- Green N
- Grella MG
- Gribauskaite J
- Griffiths E
- Griffiths E
- Griffiths M
- Grima T
- Grisin E
- Grizhja B
- Grobler DC
- Grosos C
- Grossart C
- Gubeli A
- Gudal A
- Gudal A
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- Gudlaugsdottir K
- Guevara Torres S
- Guevara R
- Guglielmo V
- Gui D
- Gul E
- Gulbinas A
- Gulcicek OB
- Gulielmi A
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- Gumar M
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- Gunawan R
- Guner A
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- Guo W
- Gupta A
- Gustafsson U
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- Gyamfi FE
- Gyanchandani N
- Gyedu A
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- Habeebullah A
- Hache-Marliere M
- Haddad N
- Hafez AT
- Hafez M
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- Hafiz S
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- Hagar A
- Haines M
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- Hajeh H
- Hakim H
- Halhouli O
- Halhouli O
- Halicioglu I
- Hall E
- Hall N
- Hall NJ
- Hall TF
- Hallam S
- Haloho A
- Hamad MGM
- Hamarshi A
- Hamasaki Hamaguchi JL
- Hamasaki J
- Hamdan A
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- Hamsho W
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- Hanley I
- Hanoun S
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- Haque M
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- Hashad E
- Hasheminia A
- Hashim A
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Effects of alirocumab on types of myocardial infarction: insights from the ODYSSEY OUTCOMES trial
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- Abbate A
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- Abhyanakar AD
- Aboyans V
- Abrantes JAM
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- Zuniga JDH
- Zurakowski A
- Zuran I
- Zweiker R
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2019
- Field of study
Aims The third Universal Definition of Myocardial Infarction (MI) Task Force classified MIs into five types: Type 1, spontaneous; Type 2, related to oxygen supply/demand imbalance; Type 3, fatal without ascertainment of cardiac biomarkers; Type 4, related to percutaneous coronary intervention; and Type 5, related to coronary artery bypass surgery. Low-density lipoprotein cholesterol (LDL-C) reduction with statins and proprotein convertase subtilisin–kexin Type 9 (PCSK9) inhibitors reduces risk of MI, but less is known about effects on types of MI. ODYSSEY OUTCOMES compared the PCSK9 inhibitor alirocumab with placebo in 18 924 patients with recent acute coronary syndrome (ACS) and elevated LDL-C (≥1.8 mmol/L) despite intensive statin therapy. In a pre-specified analysis, we assessed the effects of alirocumab on types of MI. Methods and results Median follow-up was 2.8 years. Myocardial infarction types were prospectively adjudicated and classified. Of 1860 total MIs, 1223 (65.8%) were adjudicated as Type 1, 386 (20.8%) as Type 2, and 244 (13.1%) as Type 4. Few events were Type 3 (n = 2) or Type 5 (n = 5). Alirocumab reduced first MIs [hazard ratio (HR) 0.85, 95% confidence interval (CI) 0.77–0.95; P = 0.003], with reductions in both Type 1 (HR 0.87, 95% CI 0.77–0.99; P = 0.032) and Type 2 (0.77, 0.61–0.97; P = 0.025), but not Type 4 MI. Conclusion After ACS, alirocumab added to intensive statin therapy favourably impacted on Type 1 and 2 MIs. The data indicate for the first time that a lipid-lowering therapy can attenuate the risk of Type 2 MI. Low-density lipoprotein cholesterol reduction below levels achievable with statins is an effective preventive strategy for both MI types.For complete list of authors see http://dx.doi.org/10.1093/eurheartj/ehz299</p
Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey
- Author
- Abbas Ahmed Hosam Eldin Hasan
- Abbas Ghanem
- Abbas Hazem
- Abbatini Francesca
- Abdalbakheet Duaa
- Abdallah Emad
- Abdelazim Tarek
- Abdelaziz Nabil Yassin Tammam
- Abdelglil Momen
- Abdelhalim Ahmed
- Abdelhalim Mostafa Mohammed
- Abdelhamid Ahmed
- Abdelhamid Mohamed Sayed
- Abdelkhalik Morsi Mohamed Morsi
- Abdellatif Ahmed
- Abdelmageed Mohammed Elkassaby
- Abdelmaksoud Mohamed
- Abdelmohsen Ahmed
- Abdelmomen Ahmed Ezzat Elghrieb
- Abdelmoneim Ibrahim Tharwat Mohamed
- Abdelmonem Mohamed Ahmed
- Abdelmotaleb Hussien Ali
- Abdelrafee Ahmed
- Abdelrasheed Sayed
- Abdelsayed Emad Fahim
- Abdo Nael
- Abdulatef Shehab Ahmed Ali
- Abdullah Alqahtani Ali
- Abdulrahman Chadi
- Abdur-Rahman Lukman
- Abduraboh Abdullah Fayez
- Abed Ali Ibrahim Eldawy
- Abiodun Azeez Lateef
- Abiyere Henry
- Aboelmagid Hamdy Haggag Ebrahim
- Abolnasr Khaled Samir
- Abosi-Appeadu Kessewa
- Abouelnagah Galal
- Abozeid Ahmad Mahmoud
- Abozeid Mahmoud
- Abualkhair Wael
- Abualnaja Yousra
- Abualsel Abdulmenem
- Abuosba Abdelrahman
- Abusalem Osama
- Abusiam Wael
- Abutalib Raid Abdullah
- Abuzeid Mohamed Mostafa
- Addari Giulio
- Adebowale Yusuf
- Adejumo Adeyinka
- Adel Mohammed
- Adeoluwa Ojajuni
- Adeyeye Ademola
- Adly Ramy Magdy
- Adorisio Ottavio
- Agbonrofo Peter
- Agrawal Abhishek
- Ahmad Farooq
- Ahmad Misbahu Haruna
- Ahmad Mustafa
- Ahmad Sufian
- Ahmad Suhaib
- Ahmed Abeer Abdul Hameed
- Ahmed Arooj
- Ahmed Emad Ali
- Ahmed Hassan
- Ahmed Mohamed
- Ahmed Mostafa Mahmoud
- Aitali Abdelmounaim
- Akeel Nouf
- Akhtar Khalid
- Akin Furkan Atakan
- Akinmade Akinola
- Al Eisa Abdulmohsen
- Al Hassn Ibrahim
- Al Naeb Mohamed
- Al Turki Neamat Ahmed Ali
- Al-Bahrani Ahmed
- Al-Kubati Waheeb
- Al-Masari Hayder Makki
- Al-Sadery Humood
- Alaa Mohammed
- Alabbas Haytham
- Alafghani Haitham
- Alarabi Rayan
- Alawadhi Abdulbari Mohammed
- Alawady Mohammed
- Alawfi Homoud
- Alazzam Saleh
- Albadry Ali Almahdy Ali
- Albahooth Khalid
- Albalawi Ibrahim Altedlawi
- Albeshri Khalid A.
- Aleksandr Ogoreltsev
- Alfalah Haitham
- Algatanesh Nassib
- Alghamdi Faisal Saleh
- Alghamdi Saleh
- Alghuliga Abdullah
- Alhamdany Arkan Shubber
- Alharbi Abdulhamid
- Alhazmi Barrag
- Alhazmi Waleed
- Alhedaithy Alhanouf
- Alhendawey Moaaz
- Alhussaini Mohammed Khalid
- Alhussien Fade Ahmed
- Ali Ali Sayed
- Ali Bandar Idrees A.
- Ali Doaa
- Ali Mahmoud
- Ali Mohamed Anwar Abdel Razik
- Ali Muhammad Zulfiqar
- Ali Shabeer
- Ali Syed Muhammad
- Aliyu Yakubu
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- Aljawhari Adel Ali
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- Alkhayat Mohammed Amer
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- Shomoye El-Zaki
- Sibiany Abdulrahman
- Siboe Mark M. W.
- Sidorova Lyudmila
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- Silva Jesús
- Simioni Andrea
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- Situ Oladele
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- Slavchev Mihail
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- Suliman Omar AAbu
- Tabasi Hani
- Tagg Gamal Hassan El
- Tairab Elsanousi Ibrahim Sabir
- Taki-Eldin Ahmed
- Tallon-Aguilar Luis
- Taman Mohamed
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- Tamini Nicolò
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- Tashkandi Waleed
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- Uccelli Matteo
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- Uggeri Fabio
- Uraiqat Ahmad
- Uranitsch Stefan
- Uslu Gülberk
- Valente Marina
- Valery Nekoval
- Van Daele Elke
- Van Praet Charles
- Van Ramshorst Gabrielle H.
- Vanlander Aude
- Vanommeslaeghe Hanne
- Varma Gopala Pillay
- Vázquez-Melero Alba
- Vella Ivan
- Veltri Marco
- Venturelli Paolina
- Vikrantmr Sharma
- Villwock Jennifer
- Visconti Diego
- Vishwakarma Kushagra
- Vosloo Susan
- W Njoroge P.
- Waleed Aasma
- Wali Zubair
- Waqar Shahzad Hussain
- Warusavitarne Janindra
- Waseem Talat
- Wexner Steven
- Wuraola Funmilola Olanike
- Yacir El Alami
- Yakar Fatih
- Yanaga Katsuhiko
- Yassin Nouf
- Yassine Wassim Abou
- Yeşilyurt Değercan
- Yildiz Alp
- Yousef Yousef Mohamed
- Youssef Mohamed
- Youssef Youssef Abdel Aziz
- Yves Van Nieuwenhove
- Zafar Noman
- Zahra Tarek
- Zaidi Mariam
- Zaieem Mohammad
- Zakaria Hazem M.
- Zakharenko Alexander
- Zancana Giuseppa
- Zentar Aziz
- Zese Monica
- Zewar Karem Shahin Mohamed
- Zidan Ahmed Azmy
- Zigiotto Daniele
- Zubayraeva Albina
- Zuhdy Mohammad
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020
Mortality of emergency abdominal surgery in high-, middle- and low-income countries
- Author
- A A Ahmed Ata
- A A Ibrahem
- A A Maghrabi
- A A Nasir
- A A Ne'ma Abdullah
- A Abd El Galeel
- A Abdel-Rahman Al-Aarag
- A AbdelFattah
- A Abdelgelil
- A Abdelkareem
- A Abdelmotaleb Ghazy
- A Aber
- A Abo El Magd
- A Abo Elazayem
- A Aboarab
- A Abouelnasr
- A Abouzahra
- A Adebanjo
- A Adekoya
- A Adel
- A Adel
- A Ademuyiwa
- A Adeniyi
- A Adesina
- A Adesuyi
- A Adeyeye
- A Afandy
- A Agarwal
- A Ahmed
- A Al-Mallah
- A Al-Shammari
- A Aldalaq
- A Ali
- A Ali
- A Alkammash
- A Allegri
- A Almallah
- A Almoflihi
- A Alrifaie
- A Altaf
- A Altamimi
- A Althwainy
- A Arenas
- A Ashton
- A Atef Omar
- A Austraite
- A B Zerihun
- A Badr
- A Badwy
- A Baird
- A Bamicha
- A Benevento
- A Bhangu
- A Bhargava
- A Birring
- A Boddy
- A Bondurri
- A Bonnard
- A C Manchego Bautista
- A C Manchego Bautista
- A C Roslani
- A C Snaith
- A Cacurri
- A Chambers
- A Chambers
- A Chapman
- A Chowdhury
- A Chun
- A Daltri Lazzarini Cury
- A Daqeeq
- A Das
- A Diab
- A Driscoll
- A Dubois
- A Dwydar
- A E Ajao
- A E K Musa
- A E Ward
- A Echevarria Rosas Moran
- A El Gendy
- A El Kholy
- A Elbatahgy
- A Elgebaly
- A Elkelany
- A Elkelany
- A Elkelany
- A Elkelany
- A Elkholy
- A Elshafay
- A Elwaey
- A Elwan
- A Essam Elnemr
- A Eysa
- A F Palma
- A Fadel
- A Fahiem
- A Farah
- A Faraz
- A Farquharson
- A Faure
- A Fawzy
- A Fouad
- A G N Robertson
- A Gamal Toeema
- A Garland
- A Gerosa
- A Gharib
- A Gharib
- A Gheith
- A Gomaa
- A Gouda
- A Grant
- A Gudal
- A Habeebullah
- A Hafez El-Badri Kotb
- A Hagar
- A Hammad
- A Hanks
- A Haroun
- A Hasan
- A Hasheminia
- A Hashish
- A Hassan
- A Hassan
- A Hassan
- A Hegazy Khedr
- A Horobjowsky
- A Hussein
- A Huwait
- A J Fowler
- A Jabbar
- A Karim
- A Kenibar
- A Khairy Aly
- A Khalique
- A Khan
- A Khoja
- A Khyrallh
- A Kiasat
- A Kirishnan
- A Kirupagaran
- A Kjellin
- A Kolosov
- A Kyaw Tun
- A L Contreras Vergara
- A L Mclean
- A Lasheen
- A Leal
- A Leppäniemi
- A Livesey
- A M Afifi
- A M Altwigry
- A M Attia
- A M Elkorashy
- A M Hammad
- A M Mphatsoe
- A M Saeed
- A M Shariffuddin
- A M Warwick
- A Macdonald
- A Macfarlane
- A Maffioli
- A Mahdi
- A Maniscalco
- A Marey
- A Martin
- A Mcguigan
- A Mcphee
- A Menshawy
- A Minocha
- A Mirza
- A Mistry
- A Mittal
- A Mohameden
- A Mohammad
- A Mohammed
- A Mohammed
- A Mokhtar
- A Morsi
- A Mosad
- A Munera
- A Nabawi
- A Nashaat
- A Nasr
- A Nawawi
- A Negida
- A Nesaratnam
- A Niragire
- A Nocito
- A Novak
- A Ogunyemi
- A Oluwagbemiga Lawal
- A Oosterkamp
- A Osama Elsebaaye
- A Osinowo
- A Osman Abdelaziz Elhendawy
- A P Arnaud
- A Popoola
- A Powell
- A Prabhudesai
- A R Mitul
- A Ragab Nayel
- A Ragab Soliman
- A Ramadan
- A Ramos-De La Medina
- A Rasendran
- A Rasendran
- A Rasendran
- A Rashid
- A Raslan
- A Riaz
- A Rotundo
- A Rslan
- A Rudzenskaite
- A S Mironescu
- A S North
- A Sabry
- A Sabry El-Hamouly
- A Sadek
- A Safwan Marey
- A Sakr
- A Salah Elsherbiny
- A Salleh
- A Samir
- A Sanad
- A Sayed
- A Scalabre
- A Shabkah
- A Shah
- A Shalaby
- A Sheshe
- A Skardžiukaitė
- A Solaiman El-Ma'doul
- A Spina
- A Sreedharan
- A Sriram
- A Stephen
- A Strazdas
- A Szczap
- A Tade
- A Tammam
- A Tanase
- A Tanase
- A Tang
- A Tarek
- A Tarek Hafez
- A Thorell
- A Usaityte
- A Vega Carreiro De Freitas
- A Venâncio De Sousa
- A Vlachogiorgos
- A W Anwar
- A Watts
- A Williamson
- A Wilson
- A Zani
- A Zardab
- A Zeynel A Balkan
- A Zil-E-Ali
- Abid Bin Mahamood
- B Albeladi
- B Alghamdi
- B B Ozkan
- B B Ozkan
- B Cameron
- B F Hon Khi Chong
- B Frisk
- B Magdy
- B Mansour
- B Mijuskovic
- B Nighat
- B Odeyemi
- B Pereira
- B Pereira Silvestre
- B S Kumar
- B Sieda
- B Skelly
- B Thompson
- B Van Duren
- B Weber
- B Wolf
- B-V Martian
- C A Arroyo Basto
- C A Azmitia Mendizabal
- C Agalianos
- C Anthoulakis
- C Beaton
- C Bode
- C Boereboom
- C Bowman
- C C Goh
- C C L Szeto
- C C Ramã Rez Cabrera
- C Ceriani
- C Chandrakumar
- C Clifford
- C Currow
- C Dervenis
- C Diaz-Zorrilla
- C E Lopez
- C Fahy
- C Fairfield
- C Fairfield
- C Fermani
- C Gouldthorpe
- C Grossart
- C Hand
- C Hinojosa
- C Houlden
- C I Pérez Velásquez
- C J Mcintyre
- C Jenvey
- C Jones
- C Khatri
- C Koh
- C Lee
- C Leung Chong
- C Leung Chong
- C Leung Chong
- C Lopez-Arevalo
- C López
- C M Rees
- C Magee
- C Mangan
- C Mangan
- C Marinos
- C Mason
- C Milagros Herrera Puma
- C Morales
- C Morgan
- C Muller
- C Nawara
- C Neophytou
- C Normile
- C Normile
- C Nwokoro
- C Oliveira Felipe
- C Ou Yong
- C P García Torres
- C P Major
- C Raslan
- C S Wong
- C Sampson
- C Schoewe
- C Smith
- C Tedjaatmadja
- C Tolg
- C Venugopal
- C Vinícius Barroso de Lima
- C W Ho
- C Wredberg
- C Y Chen
- C Y Tan
- D A Amin Elsorogy
- D A Raptis
- D A Romani Pozo
- D A Soeselo
- D Alkhabbaz
- D Anandkumar
- D Anderson
- D Bowley
- D Brown
- D C Marshall
- D Dabessa
- D Donoghue
- D Du Plessis
- D Duarte Cadogan
- D E Marroquín Rodríguez
- D Emadeldin
- D Fouad
- D Golding
- D Heffernan
- D Hemeda
- D Hemingway
- D I Samaraweera
- D Iyer
- D J Clark
- D Karousos
- D Kazanavicius
- D Kotecha
- D L Deckelbaum
- D Loughran
- D Lytras
- D M Cocker
- D M Elbendary Elsawahly
- D Mapasse
- D McCullagh
- D Mckechnie
- D McMorran
- D Mcnish
- D Merlini
- D Mirghani
- D Nel
- D Pata
- D Periasammy
- D R L Browning
- D Roi
- D Samuel
- D Schivo
- D Smith
- D Stewart
- D Venskutonis
- D Venskutonis
- D Vimalachandran
- D Vinicius Dos Santos
- D Youssef
- D Öfner
- D-C Zachariades
- E Abdallah
- E Abington
- E Adel Sayma
- E Ali Ahmed
- E Aljohani
- E Aljohani
- E Alnawam
- E Alqahtani
- E Barrios
- E Barrios
- E Blower
- E Borg
- E Borin
- E Brown
- E Chan
- E Court
- E D Kennedy
- E Decker
- E Dempster
- E Domini
- E E Howie
- E Elbanby
- E Etchill
- E Eyssartier
- E F Zimmermann
- E Farinella
- E G Escobar
- E G Heywood
- E Gaignard
- E Gaignard
- E Gamaly
- E Ghanem
- E Grasset
- E Grasset
- E Griffiths
- E Harper
- E Hervieux
- E Hoogakker
- E Huaman
- E Jenner
- E Jones
- E Jovine
- E Jurdell
- E Kasem
- E Kefalidi
- E Kostov
- E Laugzemys
- E M Harrison
- E M Saeed Taha
- E Macdermid
- E Macdonald
- E Mamdouh
- E Marks
- E Mcaleer
- E Monaghan
- E N W Yeung
- E Niyirera
- E Nofal
- E P Refianti Sutanto
- E Panieri
- E Preckailaite
- E Rausa
- E Schadde
- E Snyder
- E Teasdale
- E Temoche
- E Thomas
- E Upchurch
- E Veronese
- E Williams
- E Woin
- E Y A Palkhi
- F A Asele
- F A Naranjo Aristizã Bal
- F Abantanga
- F Abd El-Salam
- F Alakaloko
- F Altoe
- F Coccolini
- F Deichsel
- F Di Franco
- F Elgendy
- F Elkady
- F Elzowawi
- F Fernandez-Bueno
- F Frade
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- F Koumpa
- F M Iqbal
- F N Rahmawati
- F Nada
- F Owusu
- F Pata
- F Primavesi
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- F Sauvat
- F Schmitt
- F Tale
- F Taylor
- F Th'ng
- F Wogensen
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- F Y Lam
- F Zheng
- F-M Iordache
- G Azzie
- G Borda Luque
- G Dawnay
- G El Ashal
- G Elena
- G Gemenetzis
- G Gravante
- G H Devadasar
- G Humm
- G Irwin
- G Kouraklis
- G Landolfo
- G Lap
- G Lim
- G Luca Lamanna
- G M Machain Vega
- G Maharaj
- G Manrique Sila
- G Manrrique Sila
- G Mclachlan
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- G Tessera
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- G Williams
- H A Segovia Lohse
- H Abbas Dharamshi
- H Abudeeb
- H Ahmed
- H Ahmed El-Badawy
- H Ali
- H Ali Mostafa
- H Anderson-Knight
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- H Cruz
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- H Dawoud
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- H Jordan
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- H Koh
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- H Nair
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- H Royson
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- H Safa
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- H Tafazal
- H Thorarinsdottir
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- I Ortega-Vazquez
- I Rakita
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- I S Bharj
- I Youssef
- I-B Diaconescu
- J A Cabala Chiong
- J A Cabala Chiong
- J A Carreira
- J A Garcia-Marin
- J A Montoya Botero
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- J F Camilleri-Brennan
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- J Kabba
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- J M Vergara Celis
- J Ma
- J Marcelo Delgado
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- M A Baky Fahmy
- M A E H Mohamed
- M A Fathi Abozyed
- M Abbas
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- M Abdelraheim
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- M Abdulgawad
- M Abdulkhalek Habeeb
- M Abo Raya
- M Aboraya
- M Abozaid
- M Abuseif
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- M Agius
- M Aguilera
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- M Aledrisy
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- M Aljiffry
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- M Allam
- M Alrahawy
- M Alrajraji
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- M Alsaggaf
- M Alzahrani
- M Alzahrani
- M Ameen
- M Amer
- M Ammar
- M Amreia
- M Angel Paludi
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- M Attard
- M Baheeg
- M Bakhaidar
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- M Ghetia
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- P A Assouto
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- S Desta
- S Di Saverio
- S Dias
- S Dindyal
- S Doughan
- S El Mesery
- S El-Rabaa
- S Elshanwany
- S Elsheikh
- S Elsobky
- S Estupinian
- S F Ashraf
- S Fergusson
- S G Gosling
- S Galloway
- S Germanos
- S Ghanem
- S Giuliani
- S Gokani
- S Gosling
- S Hafiz
- S Haines
- S Hallam
- S Hassan
- S Highcock
- S Hossaini
- S Hussein
- S Irtan
- S Itopa Suleiman
- S J Chapman
- S J Lim
- S Juciute
- S K D'amours
- S K Pitt
- S Karandikar
- S Khan
- S Kharsa
- S King
- S Koh
- S Kruspi
- S Kumar
- S Kushwaha
- S Limache
- S Loizides
- S M Contreras Mérida
- S M Lakhani
- S M Sundstrom
- S Magdy Ahmed
- S Mahdi
- S Man Yeng Chiu
- S Mcaleer
- S Mehrez
- S Mikalauskas
- S Mitrasinovic
- S Mouttalib
- S Nadkarni
- S Ng
- S Nigo
- S O'Neill
- S Olori
- S Pai
- S Parthiban
- S Ramzi
- S Ray
- S Rayne
- S Razmdjou
- S Roncali
- S Roy
- S S Prasad
- S Saad
- S Said Elkolaly
- S Samy
- S Sani Ali
- S Sarsik
- S Sarwary
- S Satoskar
- S Shaikh
- S Shehata
- S Sheth
- S Shu
- S Sierra
- S Singh
- S Sinha
- S Sivaganesh
- S Stock
- S Tabiri
- S Talukder
- S Talukder
- S Tewari
- S Tharmalingam
- S Tou
- S V Kinnera
- S Vivekanantham
- S Ward
- S Wondimu
- S Zegarra
- S Zeidan
- S-H Kim
- S-P Hosein
- T A M Malik
- T Akeem Lawal
- T Alzayat
- T Arulampalam
- T B Wold
- T Barker
- T Boyce
- T Brogden
- T Chun
- T Clark
- T E Glover
- T Ebogo Ngwa
- T F Jones
- T Falconer Hall
- T Farooq
- T Fautz
- T Fernandes Giuriato
- T Fozard
- T Fozard
- T Khan
- T Kumar
- T M Drake
- T Mak
- T Muhammad Yaseen
- T Naqvi
- T Newton
- T Nouh
- T O'Connor
- T Pezas
- T Poskus
- T Razek B Marinkovic
- T S Hettiarachchi
- T Sherman
- T Stasinou
- T Urbonas
- T W Tilston
- T White
- T Xerri
- T Yaseen
- U Alamoudi
- U Gunnarsson
- U Gustafsson
- U Hantour
- U Karabacak
- U Walsh
- V Ambrozeviciute
- V Beisa
- V D Palomino Castillo
- V Despotidis
- V Gadhvi
- V Graffeille
- V Graffieille
- V Grassi
- V J P Nsengimana
- V Jennings
- V Jotautas
- V K Proctor
- V Kong
- V M Quintero Riaza
- V Parent
- V Patel
- V Punja
- V Sallinen
- V Shatkar
- V Summerour
- V Thanusan
- W Adham
- W Anwer
- W Beasley
- W C Ho
- W C Soon
- W Chachulski
- W Forno
- W Guo
- W Hawkins
- W Ho
- W Hutch
- W J Lossius
- W L Messa Aguilar
- W L Messa Aguilar
- W Milligan
- W Milligan
- W Pino
- W S Li
- W S M Kithsiri Janakantha Senanayake
- Y Abd El Salam
- Y Abd Elrasoul
- Y Abd-Elrasoul
- Y Aigrain
- Y Cengiz
- Y El Shoura
- Y Elfouly
- Y Hegazy
- Y Ibrahim
- Y Imorou Souaibou
- Y Macchitella
- Y N Neo
- Y P Mogan
- Y Rajjoub
- Y Reddy
- Y Salama
- Y Sinha
- Z Chan
- Z Dambrauskas
- Z Hassan
- Z Iftikhar
- Z Jaffry
- Z Mikwar
- Z Oof
- Z Urniezius
- Z Zhang
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2016
- Field of study
Background: Surgical mortality data are collected routinely in high-income countries, yet virtually no low- or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergency abdominal surgery, comparing findings across countries with a low, middle or high Human Development Index (HDI).
Methods: This was a prospective, multicentre, cohort study. Self-selected hospitals performing emergency surgery submitted prespecified data for consecutive patients from at least one 2-week interval during July to December 2014. Postoperative mortality was analysed by hierarchical multivariable logistic regression.
Results: Data were obtained for 10 745 patients from 357 centres in 58 countries; 6538 were from high-, 2889 from middle- and 1318 from low-HDI settings. The overall mortality rate was 1⋅6 per cent at 24 h (high 1⋅1 per cent, middle 1⋅9 per cent, low 3⋅4 per cent; P < 0⋅001), increasing to 5⋅4 per cent by 30 days (high 4⋅5 per cent, middle 6⋅0 per cent, low 8⋅6 per cent; P < 0⋅001). Of the 578 patients who died, 404 (69⋅9 per cent) did so between 24 h and 30 days following surgery (high 74⋅2 per cent, middle 68⋅8 per cent, low 60⋅5 per cent). After adjustment, 30-day mortality remained higher in middle-income (odds ratio (OR) 2⋅78, 95 per cent c.i. 1⋅84 to 4⋅20) and low-income (OR 2⋅97, 1⋅84 to 4⋅81) countries. Surgical safety checklist use was less frequent in low- and middle-income countries, but when used was associated with reduced mortality at 30 days.
Conclusion: Mortality is three times higher in low- compared with high-HDI countries even when adjusted for prognostic factors. Patient safety factors may have an important role. Registration number: NCT02179112 (http://www.clinicaltrials.gov)
Effect of alirocumab on mortality after acute coronary syndromes. An analysis of the ODYSSEY OUTCOMES randomized clinical trial
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- Abbas J
- Abbate A
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- Abhyanakar AD
- Aboyans V
- Abrantes JAM
- Abu-Fadel M
- Acevedo M
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- Agarwal H
- Aggarwal R
- Aggarwal RK
- Agnetti V
- Aguirre A
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- Ahuad Guerrero RA
- Aidar Ayoub JC
- Airaksinen JK
- Aitken D
- Akatova E
- Akhter F
- Ako J
- Akright L
- Akyea-Djamson A
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- Al-Windy NYY
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- Alvarisqueta AF
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- Zweiker R
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 04/01/2019
- Field of study
Background: Previous trials of PCSK9 (proprotein convertase subtilisin-kexin type 9) inhibitors demonstrated reductions in major adverse cardiovascular events, but not death. We assessed the effects of alirocumab on death after index acute coronary syndrome. Methods: ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) was a double-blind, randomized comparison of alirocumab or placebo in 18 924 patients who had an ACS 1 to 12 months previously and elevated atherogenic lipoproteins despite intensive statin therapy. Alirocumab dose was blindly titrated to target achieved low-density lipoprotein cholesterol (LDL-C) between 25 and 50 mg/dL. We examined the effects of treatment on all-cause death and its components, cardiovascular and noncardiovascular death, with log-rank testing. Joint semiparametric models tested associations between nonfatal cardiovascular events and cardiovascular or noncardiovascular death. Results: Median follow-up was 2.8 years. Death occurred in 334 (3.5%) and 392 (4.1%) patients, respectively, in the alirocumab and placebo groups (hazard ratio [HR], 0.85; 95% CI, 0.73 to 0.98; P=0.03, nominal P value). This resulted from nonsignificantly fewer cardiovascular (240 [2.5%] vs 271 [2.9%]; HR, 0.88; 95% CI, 0.74 to 1.05; P=0.15) and noncardiovascular (94 [1.0%] vs 121 [1.3%]; HR, 0.77; 95% CI, 0.59 to 1.01; P=0.06) deaths with alirocumab. In a prespecified analysis of 8242 patients eligible for ≥3 years follow-up, alirocumab reduced death (HR, 0.78; 95% CI, 0.65 to 0.94; P=0.01). Patients with nonfatal cardiovascular events were at increased risk for cardiovascular and noncardiovascular deaths (P<0.0001 for the associations). Alirocumab reduced total nonfatal cardiovascular events (P<0.001) and thereby may have attenuated the number of cardiovascular and noncardiovascular deaths. A post hoc analysis found that, compared to patients with lower LDL-C, patients with baseline LDL-C ≥100 mg/dL (2.59 mmol/L) had a greater absolute risk of death and a larger mortality benefit from alirocumab (HR, 0.71; 95% CI, 0.56 to 0.90; Pinteraction=0.007). In the alirocumab group, all-cause death declined wit h achieved LDL-C at 4 months of treatment, to a level of approximately 30 mg/dL (adjusted P=0.017 for linear trend). Conclusions: Alirocumab added to intensive statin therapy has the potential to reduce death after acute coronary syndrome, particularly if treatment is maintained for ≥3 years, if baseline LDL-C is ≥100 mg/dL, or if achieved LDL-C is low. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01663402
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
- Author
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- Ö
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- Ž
- Ž
- &apos
- Aahlin Ek
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader Sm
- Abdel-Wahab Nye
- Abdelaal A
- Abdelaty M
- Abdelazeam Ar
- Abdelazim G
- Abdelaziz Ma
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf Am
- Abdelrouf Dm
- Abdelshafy M
- Abdelshakour M
- Abdrabou Ak
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
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- Arnaud Ap
- Arnaud Ap
- Arshad Mm
- Arslan E
- Arsyad Hm
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- Arulampalam T
- Aruldas N
- Asaat Ul Razi S
- Asal M
- Asar Yh
- Asare-Bediako K
- Asele Fa
- Ashour A
- Ashour A
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- Ashraf Sf
- Ashtari M
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- Asi F
- Asilah Smd
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- Ata A
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- Atiyeh A
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- Atobatele K
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- Attard M
- Attia A
- Attia Am
- Augestad Km
- Aung Kp
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad Sa
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo Oo
- Aydin Mc
- Ayyar S
- Aziz Dna
- Aziz Mra
- Aziz Na
- Azizeldine Mg
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- Azodo Ia
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- Azzis O
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- Badawy M
- Badenjki Ma
- Badicel M
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- Badwi Nm
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- Badwy A
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- Baheeg M
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- Bakhaidar M
- Baki Be
- Bakr A
- Bakry Hm
- Baky Fahmy MA
- Bala M
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- Baldacchino M
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- Balila Rmh
- Balkan Aza
- Ballouhey Q
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- Balmaceda R
- Balmaceda R
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- Bamford R
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- Bamicha A
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- Bandoh D
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- Barakat Sae
- Barendegere V
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- Barmayehvar B
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- Barnacle J
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- Barreda Lma
- Barrientos Lam
- Barrios E
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- Barrios E
- Barry J
- Basilicò
- Basir Erm
- Bassem M
- Bassit Ka
- Basso Sm
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- Bautista Acm
- Bayram S
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- Bediako-Bowan A
- Behar N
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- Beisa V
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- Bekhet Nm
- Beleñ
- Belkouchi A
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- Benammi S
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- Benevento A
- Benger M
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- Benyaiche C
- Bermú
- Bernardo Cg
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- Bertuello I
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- Beuran M
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- Bezzina M
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- Bhangu A
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- Bhat S
- Bhatnagar A
- Bhattacharya S
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- Bhopal Kf
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- Birring A
- Bisset C
- Bjö
- Bjö
- Blacker S
- Blackwell J
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- Blanco-Colino R
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- Blencowe N
- Bliksø
- Blower E
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- Boakye-Yiadom K
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- Boddy A
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- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
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- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
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- Bondurri A
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- Borda-Luque G
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- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botero Jam
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- Botto N
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- Bré
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- Bratu Rm
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- Bray Ld
- Breistrand M
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- Brown J
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- Bukari M
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- Bustangi N
- Butt Mt
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- Cardozo Jt
- Cardozo Ram
- Careta Mc
- Carlucci M
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- Carpio J
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- Cassar K
- Castillo Vdp
- Castro Mr
- Catani M
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- Chachulski W
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- Chai Fy
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- Chan Z
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- Chang Ky
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- Cheah Aez
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- Chen Jhc
- Chen Ky
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- Chenn R
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- Chetta N
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- Chidambaram S
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- Chin Yr
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- Chiong Jac
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- Chiu S
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- Chong Hy
- Chong Hy
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- Chowdhury D
- Chu K
- Chun A
- Chun T
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- Chung S
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- Clegg-Lampety Jn
- Clegg-Lamptey Jn
- Clement Kd
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- Contreras E
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- Corbellini C
- Corbellino M
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- Correa Jc
- Corro-Diaz S
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- Costa-Maia J
- Costa-Maia J
- Costas-Chavarri A
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- Cox D
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- Dé
- D&apos
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- D&apos
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- Da Silva LA
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- Daniyan M
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- Daqeeq A
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- Das A
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- Dashnyam E
- Dassah V
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- Davenport R
- Davies J
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- Dawnay G
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- Dayie M
- De Boni D
- De Bono P
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- De Castro Segundo LCB
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- De La Medina AR
- de Leó
- De Leon MZP
- De Leon MZP
- de Lima CVB
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- Deichsel F
- Del Basso C
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- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
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- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
- Dhillon D
- Di Franco F
- Di Martino N
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- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu Ib
- Dias S
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
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- Dindyal S
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
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- Dorani Rmnr
- Dorismé
- Dos Santos DV
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- Drake Tm
- Driscoll A
- Drungilas M
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- Dueñ
- Duffy L
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- Durand Sya
- Dwydar A
- Ebdewi H
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- Eduard P
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- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Salam YA
- El Sayed GS
- El Sayed IM
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- El-Dien Ks
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- El-Gizawy E
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- El-Kashef H
- El-Latif Nka
- El-Ma&apos
- El-Rabaa S
- El-Sagheer N
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- El-Sawy A
- El-Sehily A
- El-Shahat Ns
- El-Sheemy H
- El-Taher E
- Elabdin Hz
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem Aa
- Elazoul M
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- Elbanby Es
- Elbatahgy A
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- Eldeen Ea
- Eldin Mab
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- Elebute O
- Elena G
- Elfarargy A
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- Elfeki H
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- Elfouly Y
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- Elgendy Fi
- Elgheriany M
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- Elkelany A
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- Elkholy A
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- Elkolaly Ss
- Elkorashy Am
- Ellison Q
- Elmashala A
- Elmasry M
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- Elmihy S
- Elnagar A
- Elnajjar Ma
- Elnemr Ae
- Elrasoul Ya
- Elrazek Aa
- Elsabbagh N
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- Elsawahly Dme
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
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- Elsayed Zm
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- Elsehimy M
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- Elshaar M
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- Elshaer M
- Elshaer M
- Elshafay Ae
- Elshami M
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- Elsharkawy Aa
- Elsheikh S
- Elsherbiney S
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- Elsherif Fa
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy Deaa
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
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- Espinoza Kt
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- Essam A
- Essam Aa
- Essam M
- Essoun S
- Esteban E
- Estee Mm
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
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- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
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- Fahiem A
- Fahim M
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- Fairfield C
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- Fairfield C
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- Falco N
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- Farag S
- Farah A
- Farahat Mm
- Faraz A
- Fares M
- Farfan Esf
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- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
- Fergusson Sj
- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
- Florez Ljg
- Foco M
- Fok Cyj
- Fontana T
- Foo Cc
- Forlin L
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- Fouad D
- Fouad D
- Fourcade L
- Fowler Aj
- Fozard T
- Fozard T
- Frade F
- Fraga Gp
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- Francois P
- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
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- Gü
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- Gaafar S
- Gaarder T
- Gad A
- Gad Mo
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- Gadhvi V
- Gado A
- Gaiž
- Gaignard E
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- Gala T
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- Galiqi G
- Galleano R
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- Gamal D
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- Gamil D
- Gan C
- Gan Yy
- Gani Ma
- Garaycochea O
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- Garcia-Marin Ja
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- Garland A
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- Gemeah M
- Gemenetzis G
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- George R
- Germanos S
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- Gerosa A
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- Geuoshy A
- Ghaben A
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- Ghannam M
- Gharib A
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- Ghazy Aa
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- Ghetia M
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- Giuriato Tf
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- Grobler Dc
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- Guevara R
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- Gulielmi A
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- Gustafsson U
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- Hafiz S
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- Hagar A
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- Halhouli O
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- Halicioglu I
- Hall E
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- Hamaguchi Jlh
- Hamarshi A
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- Hamdan A
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- Hany E
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- Har Pa
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- Hasanah A
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- Hashad E
- Hasheminia A
- Hashim A
- Hashish A
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- Haslegrave A
- Hasnan Mb
- Hassaan A
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- Hassan A
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- Hassan Ata
- Hassan I
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- Hassanein Ab
- Havemann I
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- Huwait A
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- Iannone I
- Ibraheem Aa
- Ibraheem Hi
- Ibrahem Aa
- Ibrahem Aa
- Ibrahim A
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- Ibrahim A
- Ibrahim Am
- Ibrahim E
- Ibrahim Em
- Ibrahim I
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- Ibrahim M
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- Iftekhar F
- Iftikhar Z
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- Ihediwa G
- Imoro O
- Ingabire Jca
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- Ioannidis O
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- Kamarulzamil Sna
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- Kasputyte S
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- Kiasat A
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- Kim My
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- King R
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- Klappenbach R
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- Komolafe O
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- Kong C
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- Kose E
- Koskenvuo L
- Kostov E
- Kotb Ahe
- Kotecha D
- Koto Mz
- Kotobi H
- Koumpa F
- Kouraklis G
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- Laugzemys E
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- Laurie K
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- Law Jh
- Lawal A
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- Lawal T
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- Lawani I
- Lawther R
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- Lee C
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- Lee F
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- Leone N
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- Leusink A
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- Loaloa Mr
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- Loizides S
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- Macfarlane A
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- Mapasse D
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- Margaritis M
- Mariani A
- Marinkovic B
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- Marks E
- Marples L
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- Martian Bv
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- Miranda C
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- Mogan Yp
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- Mohamed F
- Mohamed I
- Mohamed M
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- Mohamed Maeh
- Mohamed Mm
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- Monteleone M
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- Montrimaite M
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- Moodley Y
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- Mostafa Ha
- Mostafa M
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- Mowafy B
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- Mshelbwala P
- Msiska N
- Msosa V
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- Mukuzunga C
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- Nanthakumaran S
- Napolitano L
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- Naqvi Sa
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- Naranjo Aristizã
- Narayanan R
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- Nevieraite V
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- Nsengimana Vjp
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone