978 research outputs found

    Checking strong open congruence in χ-calculus

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    The χ-calculus is an important evolution for mobile process calculi. Open congruence is widely studied in χ-calculus. However, there still lacks an algorithm for checking this bisimulation relation. In this paper, the symbolic technique is applied to the research of χ-calculus and an efficient characterization for strong open congruence which does not involve quantification over substitutions is given. Based on it, an algorithm, which instantiates bound names 'on-the-fly', is developed to check strong open congruence for finite control processes

    Numerical simulation of thermal and residual stress fields induced by lined pipe welding

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    This paper investigates numerical thermal fields and residual stresses induced by single-pass weld overlay (lap-weld) and girth welding (butt-weld) in lined pipe using Tungsten Inert Gas (TIG) welding. A distributed power density of the moving heat source based on Goldak’s ellipsoid heat flux distribution is used in a Finite Element (FE) simulation of the lined pipe welding process. In addition, radiation and convection have been incorporated in heat transfer coefficient user-subroutines for the FE code ABAQUS. The 3-D FE model approach has been validated using previous experimental results published for butt-welds of similar sections of carbon-manganese C-Mn steel pipe lined with stainless steel. The FE model has been developed to determine the thermal isotherms and residual stress distributions from weld overlay and girth welding. The use of an inner layer known as a liner has a considerable influence on the thermal history and residual stress distributions. Furthermore, the influence of the weld overlay has been examined thermally and mechanically as it is a key factor that can affect the quality of lined pipe welding

    A population of luminous accreting black holes with hidden mergers

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    Major galaxy mergers are thought to play an important part in fuelling the growth of supermassive black holes. However, observational support for this hypothesis is mixed, with some studies showing a correlation between merging galaxies and luminous quasars and others showing no such association. Recent observations have shown that a black hole is likely to become heavily obscured behind merger-driven gas and dust, even in the early stages of the merger, when the galaxies are well separated (5 to 40 kiloparsecs). Merger simulations further suggest that such obscuration and black-hole accretion peaks in the final merger stage, when the two galactic nuclei are closely separated (less than 3 kiloparsecs). Resolving this final stage requires a combination of high-spatial-resolution infrared imaging and high-sensitivity hard-X-ray observations to detect highly obscured sources. However, large numbers of obscured luminous accreting supermassive black holes have been recently detected nearby (distances below 250 megaparsecs) in X-ray observations. Here we report high-resolution infrared observations of hard-X-ray-selected black holes and the discovery of obscured nuclear mergers, the parent populations of supermassive-black-hole mergers. We find that obscured luminous black holes (bolometric luminosity higher than 2x10^44 ergs per second) show a significant (P<0.001) excess of late-stage nuclear mergers (17.6 per cent) compared to a sample of inactive galaxies with matching stellar masses and star formation rates (1.1 per cent), in agreement with theoretical predictions. Using hydrodynamic simulations, we confirm that the excess of nuclear mergers is indeed strongest for gas-rich major-merger hosts of obscured luminous black holes in this final stage.Comment: To appear in the 8 November 2018 issue of Nature. This is the authors' version of the wor

    Topological Photonics

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    Topology is revolutionizing photonics, bringing with it new theoretical discoveries and a wealth of potential applications. This field was inspired by the discovery of topological insulators, in which interfacial electrons transport without dissipation even in the presence of impurities. Similarly, new optical mirrors of different wave-vector space topologies have been constructed to support new states of light propagating at their interfaces. These novel waveguides allow light to flow around large imperfections without back-reflection. The present review explains the underlying principles and highlights the major findings in photonic crystals, coupled resonators, metamaterials and quasicrystals.Comment: progress and review of an emerging field, 12 pages, 6 figures and 1 tabl

    On the link between ocean biota emissions, aerosol, and maritime clouds: Airborne, ground, and satellite measurements off the coast of California

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    Surface, airborne, and satellite measurements over the eastern Pacific Ocean off the coast of California during the period between 2005 and 2007 are used to explore the relationship between ocean chlorophyll a, aerosol, and marine clouds. Periods of enhanced chlorophyll a and wind speed are coincident with increases in particulate diethylamine and methanesulfonate concentrations. The measurements indicate that amines are a source of secondary organic aerosol in the marine atmosphere. Subsaturated aerosol hygroscopic growth measurements indicate that the organic component during periods of high chlorophyll a and wind speed exhibit considerable water uptake ability. Increased average cloud condensation nucleus (CCN) activity during periods of increased chlorophyll a levels likely results from both size distribution and aerosol composition changes. The available data over the period of measurements indicate that the cloud microphysical response, as represented by either cloud droplet number concentration or cloud droplet effective radius, is likely influenced by a combination of atmospheric dynamics and aerosol perturbations during periods of high chlorophyll a concentrations

    Macroscale evolutionary patterns of flight muscle dimorphism in the carrion beetle Necrophila japonica

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    Some insect species exhibit polymorphisms in flight muscles or wings, which provide opportunities for studying the factors that drive dispersal polymorphisms and the evolution of flightlessness in insects. We investigated the macroscale evolutionary pattern of flightlessness in the widespread Japanese beetle Necrophila japonica (Coleoptera: Silphidae), which exhibits flight muscle dimorphisms using phylogeographic approaches. N. japonica lives in both stable and unstable habitats, and the flight muscle dimorphisms may have been maintained through the use of these diverse habitats. We studied the distribution pattern of the proportion of individuals lacking flight muscles in relation to the genetic differentiation among geographic populations using an 842-base pair sequence of the COI-II gene. Both flight-capable and flightless individuals occurred over the distribution area, and the flight muscle condition showed no significant phylogeographic pattern. Several populations comprised flight-capable individuals only, whereas few comprised flightless ones only. Demographic expansion was suggested for major clades of COI-II haplotypes, and the genetic differentiation showed an isolation-by-distance pattern among the populations in Japan. The proportion of flightless individuals was higher in a population with a higher annual mean temperature and with higher genetic diversity among individuals. These results indicate that geographic expansion occurred recently while flight muscle dimorphisms have been maintained, that flight-capable individuals have colonized cooler (peripheral) habitats, and that flightlessness has increased in long-persisting populations as suggested by high genetic diversity

    Rotational knee laxity: Reliability of a simple measurement device in vivo

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    <p>Abstract</p> <p>Background</p> <p>Double bundle ACL reconstruction has been demonstrated to decrease rotational knee laxity. However, there is no simple, commercially-available device to measure knee rotation. The investigators developed a simple, non-invasive device to measure knee rotation. In conjunction with a rigid boot to rotate the tibia and a force/moment sensor to allow precise determination of torque about the knee, a magnetic tracking system measures the axial rotation of the tibia with respect to the femur. This device has been shown to have acceptable levels of test re-test reliability to measure knee rotation in cadaveric knees.</p> <p>Methods</p> <p>The objective of this study was to determine reliability of the device in measuring knee rotation of human subjects. Specifically, the intra-tester reliability within a single testing session, test-retest reliability between two testing sessions, and inter-tester reliability were assessed for 11 male subjects with normal knees.</p> <p>Results</p> <p>The 95% confidence interval for rotation was less than 5° for intra-tester, test-retest, and inter-tester reliability, and the standard error of measurement for the differences between left and right knees was found to be less than 3°.</p> <p>Conclusion</p> <p>It was found that the knee rotation measurements obtained with this device have acceptable limits of reliability for clinical use and interpretation.</p

    Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis

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    Metastasis is the leading cause of death of patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonization are poorly understood. Here we deploy comparative genomics to identify and validate clinically relevant drivers of melanoma metastasis. To do this we identified a set of 976 genes whose expression level was associated with a poor outcome in patients from two large melanoma cohorts. We next characterised the genomes and transcriptomes of mouse melanoma cell lines defined as weakly metastatic and their highly metastatic derivatives. By comparing expression data between species we identified Lunatic Fringe (LFNG), amongst 28 genes whose expression level is predictive of poor prognosis, and whose altered expression is associated with a pro-metastatic phenotype in mouse melanoma cells. CRISPR/Cas9 mediated knockout of Lfng dramatically enhanced the capability of weakly metastatic melanoma cells to metastasize in vivo, a phenotype that could be rescued with the Lfng cDNA. Notably, genomic alterations disrupting LFNG are found exclusively in human metastatic melanomas sequenced as part of The Cancer Genome Atlas. Using comparative genomics we show that LFNG expression plays a functional role in regulating melanoma metastasis

    Measurement of Z/gamma*+jet+X angular distributions in ppbar collisions at sqrt{s}=1.96 TeV

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    We present the first measurements at a hadron collider of differential cross sections for Z+jet+X production in delta phi(Z, jet), |delta y(Z, jet)| and |y_boost(Z, jet)|. Vector boson production in association with jets is an excellent probe of QCD and constitutes the main background to many small cross section processes, such as associated Higgs production. These measurements are crucial tests of the predictions of perturbative QCD and current event generators, which have varied success in describing the data. Using these measurements as inputs in tuning event generators will increase the experimental sensitivity to rare signals.Comment: Published in Physics Letters B 682 (2010), pp. 370-380. 15 pages, 6 figure

    Search for the standard model Higgs boson in tau final states

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    We present a search for the standard model Higgs boson using hadronically decaying tau leptons, in 1 inverse femtobarn of data collected with the D0 detector at the Fermilab Tevatron ppbar collider. We select two final states: tau plus missing transverse energy and b jets, and tau+ tau- plus jets. These final states are sensitive to a combination of associated W/Z boson plus Higgs boson, vector boson fusion and gluon-gluon fusion production processes. The observed ratio of the combined limit on the Higgs production cross section at the 95% C.L. to the standard model expectation is 29 for a Higgs boson mass of 115 GeV.Comment: publication versio
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