Post-embryonic development of intramandibular glands of Friesella schrottkyi (Friese, 1900) (Hymenoptera: Apidae) workers

Exocrine glands play important role in social organization of insects, such as caste and inter-caste differentiation. Due their functional and structural plasticity, morphological studies on such glands contribute to better understanding the biology of social bees. Therefore, the aim of the study was to characterize the sequence of the post-embryonic development of intramandibular glands of Friesella schrottkyi (Friese, 1900) (Hymenoptera: Apidae) workers using histological and histochemical analyses. The mandibles of pupae at different developmental stages and newly emerged adults were analyzed. The intramandibular glands of F. schrottkyi presented two types: class I glands, in the mandible epidermis and class III glands, inside the mandible cavity that open onto external surface. The intramandibular glands of F. schrottkyi developed during the transition from the prepupae to the white-eyed pupae, as shown by the morphological changes. Black-eyed pupae of F. schrottkyi presented fully developed intramandibular glands

Physiological selectivity of insecticides from different chemical groups and cuticle thickness of Protonectarina sylveirae (Saussure) and Brachygastra lecheguana (Latreille)

O uso de inseticidas mais tóxicos para uma praga do que a saúde natural pode favorecer o salvamento desses organismos benéficos. Este estudo teve como objetivos fisiológicos distanciadores de inseticidas de separações científicas para Vespidae Protonectarina sylveirae (Saussure, 1854) e Brachygastra lecheguana. (Latterille, 1824) e espessura de cutícula para avaliação da tolerância entre os 2 anos estes mesmos inseticidas. Como imersas foram folhas de milho (10 x 10 cm) em solução inseticida em dose (100%), subdose (50%) e água destilada (controle) por 5 segundos. Nós podemos ler as folhas e depois embalamos em placas de Petri.Como 20 vespas, por placa, receberam 10% de mel e as placas foram fechadas com tecido de organza fino e elastificadas. Após 24 horas, avaliamos uma porcentagem de vespas mortas. O inseticida alfa-cipermetrina foi altamente tóxico para P. sylveirae e B. lecheguana em dose (100%) e subdose (50%). Os inseticidas Novaluron, chlorantraniliprole, spinosad e indoxacarb foram pouco tóxicos para P. sylveirae e B. lecheguana. dose (100%) e subdose (50%). A alta toxicidade dos inseticidas metomil + novalurom, clorantraniliprole + lambda-cialotrina e deltametrina a P. sylveirae corresponde à menor espessura da cutícula.Portanto, os inseticidas novalurom, clorantraniliprole, spinosad e indoxacarb da selectividade fisiológica para P. sylveirae e B. lecheguana .

Dificuldades no tratamento de pacientes disfágicos em decorrência de Alzheimer no Sistema Único de Saúde (SUS)

A disfagia se apresenta como um distúrbio de deglutição característico em pacientes idosos com sinais e sintomas específicos, que tem como característica alterações em qualquer etapa ou entre etapas da dinâmica da deglutição, podendo ser congênita ou adquirida. Esse trabalho tem como objetivo, compreender as singularidades terapêuticas que o SUS oferece e, principalmente, a importância do tratamento desta patologia, no intuito de minimizar as dificuldades e melhorar a qualidade de vida. A Doença de Alzheimer, comum em pacientes idosos, caracteriza-se por manifestar perda progressiva da memória e do raciocínio abstrato. A localização da lesão é no início basal de Meynert, por degeneração de seus neurônios e consequente depleção de acetilcolina no córtex cerebral, causando possíveis disfagias que afetem a motricidade da fala. Tendo em vista os diversos empecilhos no tratamento, além de uma grande dificuldade no acesso desses pacientes ao Sistema Único de Saúde, buscam-se estratégias para tornar o SUS acolhedor para maiores feitos e progressos no tratamento. Os resultados mostraram que no SUS, apesar de serem feitos tratamentos e acompanhamentos para a DA, não há uma resolubilidade eficaz, visto que são poucos os estudos em torno desse assunto que comprovem uma influência maior do sistema único de saúde

Development and validation of HERWIG 7 tunes from CMS underlying-event measurements

This paper presents new sets of parameters (“tunes”) for the underlying-event model of the HERWIG7 event generator. These parameters control the description of multiple-parton interactions (MPI) and colour reconnection in HERWIG7, and are obtained from a fit to minimum-bias data collected by the CMS experiment at s=0.9, 7, and 13Te. The tunes are based on the NNPDF 3.1 next-to-next-to-leading-order parton distribution function (PDF) set for the parton shower, and either a leading-order or next-to-next-to-leading-order PDF set for the simulation of MPI and the beam remnants. Predictions utilizing the tunes are produced for event shape observables in electron-positron collisions, and for minimum-bias, inclusive jet, top quark pair, and Z and W boson events in proton-proton collisions, and are compared with data. Each of the new tunes describes the data at a reasonable level, and the tunes using a leading-order PDF for the simulation of MPI provide the best description of the dat

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe

Measurement of B-c(2S)(+) and B-c*(2S)(+) cross section ratios in proton-proton collisions at root s=13 TeV

Peer reviewe

Reconstruction of signal amplitudes in the CMS electromagnetic calorimeter in the presence of overlapping proton-proton interactions

A template fitting technique for reconstructing the amplitude of signals produced by the lead tungstate crystals of the CMS electromagnetic calorimeter is described. This novel approach is designed to suppress the contribution to the signal of the increased number of out-of-time interactions per beam crossing following the reduction of the accelerator bunch spacing from 50 to 25 ns at the start of Run 2 of the LHC. Execution of the algorithm is sufficiently fast for it to be employed in the CMS high-level trigger. It is also used in the offline event reconstruction. Results obtained from simulations and from Run 2 collision data (2015-2018) demonstrate a substantial improvement in the energy resolution of the calorimeter over a range of energies extending from a few GeV to several tens of GeV.Peer reviewe

Observation of the Production of Three Massive Gauge Bosons at root s=13 TeV

The first observation is reported of the combined production of three massive gauge bosons (VVV with V = W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV. The analysis is based on a data sample recorded by the CMS experiment at the CERN LHC corresponding to an integrated luminosity of 137 fb(-1). The searches for individualWWW, WWZ, WZZ, and ZZZ production are performed in final states with three, four, five, and six leptons (electrons or muons), or with two same-sign leptons plus one or two jets. The observed (expected) significance of the combinedVVV production signal is 5.7 (5.9) standard deviations and the corresponding measured cross section relative to the standard model prediction is 1.02(-0.23)(+0.26). The significances of the individual WWW and WWZ production are 3.3 and 3.4 standard deviations, respectively. Measured production cross sections for the individual triboson processes are also reported

Search for a light pseudoscalar Higgs boson in the boosted mu mu tau tau final state in proton-proton collisions at root s=13 TeV

A search for a light pseudoscalar Higgs boson (a) decaying from the 125 GeV (or a heavier) scalar Higgs boson (H) is performed using the 2016 LHC proton-proton collision data at root s = 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), collected by the CMS experiment. The analysis considers gluon fusion and vector boson fusion production of the H, followed by the decay H -> aa -> mu mu tau tau, and considers pseudoscalar masses in the range 3.6 aa -> mu mu tau tau, down to 1.5 (2.0)x10(-4) for m(H) = 125 (300) GeV. Model-dependent limits on B(H -> aa) are set within the context of two Higgs doublets plus singlet models, with the most stringent results obtained for Type-III models. These results extend current LHC searches for heavier a bosons that decay to resolved lepton pairs and provide the first such bounds for an H boson with a mass above 125 GeV.Peer reviewe