51 research outputs found

    Implementing RFID in Production Systems: A Case Study from a Confectionery Manufacturer

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    This paper presents a case study on the research and development of an RFID-based work-in-progress container tracking system at a confectionery manufacturer. We report on the management of the RFID project, the system design and the economic evaluation of the solution as compared to the situation before implementing RFID. We discuss the case from a practitioner\u27s view as well as from an academic view regarding the theoretical implications that can be drawn from it. The lessons learned from the project can help other companies to better anticipate the challenges they may experience and make them aware of the possible ways to cope with such challenges prior to starting an RFID implementation. Available at: https://aisel.aisnet.org/pajais/vol2/iss2/4

    Effects of anti-ischaemic drug therapy in silent myocardial ischaemia type I: the Swiss Interventional Study on Silent Ischaemia type I (SWISSI I): a randomized, controlled pilot study

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    Aims To determine the effect of anti-ischaemic drug therapy on long-term outcomes of asymptomatic patients without coronary artery disease (CAD) history but silent exercise ST-depression. Methods and results In a randomized multicentre trial, 263 of 522 asymptomatic subjects without CAD but at least one CAD risk factor in whom silent ischaemia by exercise ECG was confirmed by stress imaging were asked to participate. The 54 (21%) consenting patients were randomized to anti-anginal drug therapy in addition to risk factor control (MED, n = 26) or risk factor control-only (RFC, n = 28). They were followed yearly for 11.2 ± 2.2 years. During 483 patient-years, cardiac death, non-fatal myocardial infarction, or acute coronary syndrome requiring hospitalization or revascularization occurred in 3 (12%) of MED vs. 17 (61%) of RFC patients (P < 0.001). In addition, MED patients had consistently lower rates of exercise-induced ischaemia during follow-up, and left ventricular ejection fraction remained unchanged (−0.7%, P = 0.597) in contrast to RFC patients in whom it decreased over time (−6.0%, P = 0.006). Conclusion Anti-ischaemic drug therapy and aspirin seem to reduce cardiac events in subjects with asymptomatic ischaemia type I. In such patients, exercise-induced ST-segment depression should be verified by stress imaging; if silent ischaemia is documented, anti-ischaemic drug therapy and aspirin should be considere

    A Study of Dynamic Phase Adaptation Using a Dynamic Multicore Processor

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    Heterogeneous processors such as ARM’s big.LITTLE have become popular for embedded systems. They offer a choice between running workloads on a high performance core or a low-energy core leading to increased energy efficiency. However, the core configurations are fixed at design time which offers a limited amount of adaptation. Dynamic Multicore Processors (DMPs) bridge the gap between homogeneous and fully reconfigurable systems. Cores can fuse dynamically to adapt the computational resources to the needs of different workloads. There exists multiple examples of DMPs in the literature, yet the focus has mainly been on static partitioning. This paper conducts the first thorough study of the potential for dynamic reconfiguration of DMPs at runtime. We study how performance varies with static partitioning and what software optimizations are required to achieve high performance. We show that energy consumption is reduced considerably when adapting the number of cores to program phases, and introduce a simple online model which predicts the optimal number of cores to use to minimize energy consumption while maintaining high performance. Using the San Diego Vision Benchmark Suite as a use case, the dynamic scheme leads to ∼40% energy savings on average without decreasing performance.</jats:p

    Preoperative transarterial embolization of vertebral metastases

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    The aim of this study was to evaluate the impact of preoperative devascularization of spinal metastases in relation to the preembolization tumor vascularization degree and in relation to the intraoperative blood loss. Twenty-four patients underwent preoperative transarterial embolization of hypervascular spinal metastases. Each tumor was assigned a vascularization grade (I-III) according to tumor blush after contrast agent injection in the main feeding artery. Embolization was performed with polyvinyl alcohol particles in all patients. Surgical reports were reviewed in terms of estimated blood loss. A mild hypervascularization was found in three patients (group I), medium in six patients (group II) and extensive in 15 patients (group III). In 22 out of 24 patients embolization could be performed with a complete devascularization. In two patients, only partial embolization could be performed, due to the main feeding artery arising from the artery of Adamkiewicz. In patients with complete devascularization the mean intraoperative blood loss was 1,900ml, whereas in the two patients who were not embolized it was 5,500ml. Intraoperative blood loss was not correlated to the vascularization grade. Angiography and embolization could be performed in all patients without causing permanent neurologic deficit, skin or muscle necrosis. The surgeons concluded that radical tumor resection after embolization was facilitated. Intraoperative blood loss is not correlated with the pre-interventional vascularization degree, if complete devascularization can be achieved with embolization. Preoperative embolization of vertebral hypervascular tumors is safe, effective and facilitates tumor resectio

    Close-to-threshold Meson Production in Hadronic Interactions

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    Studies of meson production at threshold in the hadron--hadron interaction began in the fifties when sufficient energies of accelerated protons were available. A strong interdependence between developments in accelerator physics, detector performance and theoretical understanding led to a unique vivid field of physics. Early experiments performed with bubble chambers revealed already typical ingredients of threshold studies, which were superseded by more complete meson production investigations at the nucleon beam facilities TRIUMF, LAMPF, PSI, LEAR and SATURNE. Currently, with the advent of the new cooler rings as IUCF, CELSIUS and COSY the field is entering a new domain of precision and the next step of further progress. The analysis of this new data in the short range limit permits a more fundamental consideration and a quantitative comparison of the production processes for different mesons in the few--body final states. The interpretation of the data take advantage of the fact that production reactions close-to-threshold are characterized by only a few degrees of freedom between a well defined combination of initial and exit channels. Deviations from predictions of phase-space controlled one-meson-exchange models are indications of new and exciting physics. Precision data on differential cross sections, isospin and spin observables -- partly but by no means adequately available -- are presently turning up on the horizon. There is work for the next years and excitement of the physics expected. Here we try to give a brief and at the same time comprehensive overview of this field of hadronic threshold production studies.Comment: 100 pages, Review article to be published in Prog. Part. Nucl. Phys. Vol. 49, issue 1 (2002

    The Evolutionary Dynamics of the Lion Panthera leo Revealed by Host and Viral Population Genomics

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    The lion Panthera leo is one of the world's most charismatic carnivores and is one of Africa's key predators. Here, we used a large dataset from 357 lions comprehending 1.13 megabases of sequence data and genotypes from 22 microsatellite loci to characterize its recent evolutionary history. Patterns of molecular genetic variation in multiple maternal (mtDNA), paternal (Y-chromosome), and biparental nuclear (nDNA) genetic markers were compared with patterns of sequence and subtype variation of the lion feline immunodeficiency virus (FIVPle), a lentivirus analogous to human immunodeficiency virus (HIV). In spite of the ability of lions to disperse long distances, patterns of lion genetic diversity suggest substantial population subdivision (mtDNA ΦST = 0.92; nDNA FST = 0.18), and reduced gene flow, which, along with large differences in sero-prevalence of six distinct FIVPle subtypes among lion populations, refute the hypothesis that African lions consist of a single panmictic population. Our results suggest that extant lion populations derive from several Pleistocene refugia in East and Southern Africa (∼324,000–169,000 years ago), which expanded during the Late Pleistocene (∼100,000 years ago) into Central and North Africa and into Asia. During the Pleistocene/Holocene transition (∼14,000–7,000 years), another expansion occurred from southern refugia northwards towards East Africa, causing population interbreeding. In particular, lion and FIVPle variation affirms that the large, well-studied lion population occupying the greater Serengeti Ecosystem is derived from three distinct populations that admixed recently

    Development of an RFID based track and trace system: experiences and lessons learned from a confectionary manufacturer

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    This paper presents a case study on the research and development of an RFID-based work-in-progress container tracking system at a confectionery manufacturer. We report on the management of the RFID project, the system design and the economic evaluation of the solution as compared to the situation before implementing RFID. We discuss the case from a practitioner's view as well as from an academic view regarding the theoretical implications that can be drawn from it. The lessons learned from the project can help other companies to better anticipate the challenges they may experience and make them aware of the possible ways to cope with such challenges prior to starting an RFID implementation
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