UV-mediated photofunctionalization of biofunctional coating enhances the surface characteristics and biological properties of titanium

Orientador: Valentim Adelino Ricardo BarãoDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de PiracicabaResumo: Infecções nos tecidos circunjacentes aos implantes dentários são consideradas fatores de risco para a osseointegração na fase inicial de cicatrização, contribuindo para a maior ocorrência de falhas iniciais. Modificações topográficas e químicas da superfície do titânio (Ti) vem sendo estudadas com o objetivo de melhorar as propriedades biológicas e atividade antimicrobiana de implantes dentários. A fotofuncionalização mediada por raios ultravioleta (UV) modifica as características físico-químicas da superfície de Ti e melhora as propriedades biológicas dos implantes dentários. Entretanto, o papel da fotofuncionalização UV em superfícies biofuncionais de Ti na atividade antimicrobiana e fotocatalítica são desconhecidas e foram investigadas neste estudo. Discos de titânio comercialmente puro (Ticp) foram divididos em quatro grupos: (1) maquinado sem a aplicação de luz UV [Ticp UV-]; (2) tratado por plasma eletrolítico de oxidação (PEO) sem a aplicação de luz UV [PEO UV-]; (3) maquinado com a aplicação de luz UV [Ticp UV+]; (4) tratado por PEO com a aplicação de luz UV [PEO UV+]. As superfícies foram caracterizadas por meio de microscopia confocal a laser, microscopia eletrônica de varredura (MEV), perfilometria, difratometria de raios-X (DRX), espectroscopia de energia dispersiva (EDS), espectroscopia de fotoelétrons excitados por raios-X (XPS) e molhabilidade. O teste de degradação do azul de metileno foi utilizado para a avaliação da atividade fotocatalítica. A adsorção da proteína albumina foi avaliada por meio do método do ácido bicinconínico. Para o ensaio microbiológico, a adesão de Streptococcus sanguinis desenvolvido na superfície dos discos por 1 h e 6 h foi avaliada por meio das unidades formadoras de colônia. O tratamento com PEO aumentou a rugosidade e molhabilidade da superfície de Ti (p 0.05). The photofunctionalization of a biofunctional coating seems to be a promising alternative for dental implants as it increases blood plasma protein adsorption and provides reduction of initial bacterial adhesionMestradoProtese DentalMestra em Clínica OdontológicaCAPE

Perbaikan Kualitas Produk Furniture Dengan Menggunakan Pendekatan Dmaic di PT. Prospek Manunggal Era Industry

PT. Prospek Manunggal Era Industry merupakan sebuah pabrik yang bergerak di bidang furniture dengan bahan baku utamanya rotan dan marmer terletak di Jalan Wates Negoro, Kec Ngoro. Pengendalian kualitas mencakup keseluruhan kegiatan produksi, mulai dari perencanaan (Plan), kemudian mengimplementasikan perencanaan itu menjadi kenyataan (Do), dan meninjau kembali sejauh mana kesesuaian antara hasil dengan rencana semula (Check). Selanjutnya harus dilakukan perbaikan yang perlu agar kesesuaian antara hasil dengan rencana tercapai (Action). Pengendalian kualitas adalah sebuah diagnostic. Apabila terjadi sebuah produk cacat muncul, penyebabnya dicari dan dilakukan perbaikan, untuk itu metode yang digunakan dengan DMAIC. Di mana penggunaan metode ini disesuaikan dengan kebutuhan dan jenis permasalahannya. Dari DMAIC (define, measure, analyze, improve, control) semua masalah akan dapat teratasi dan metode ini dapat memberikan usulan perbaikan dan dapat diimplementasikan pada perusahaan ini. Dengan menggunakan diagram pareto, menghitung DPO dan DPMO untuk mengetahui besar sigma. Dengan menggunakan DMAIC menunjukkan banyak perubahan yang nyata pada perusahaan dan berarti perusahaan memerlukan perbaikan dengan menambah alat bantu

Confiabilidad de un instrumento para clasificar al recién nacido de acuerdo con la complejidad de la atención

Na maioria das maternidades, a classificação, a avaliação e a definição da unidade a encaminhar o recém-nascido (RN) após o nascimento são realizadas pelo médico. A\ud avaliação ocorre na sala de parto considerando: peso ao nascer; idade gestacional;\ud condutas que definem quadro clínico e doença. Este estudo observacional teve\ud como objetivo avaliar a confiabilidade de um instrumento de classificação de RN. A pesquisa foi realizada no berçário de um hospital público, São Paulo. Nove enfermeiras\ud aplicaram o instrumento a 63 RN, sendo duas simultaneamente em cada um dos\ud cinco setores do berçário. Verificou-se que o nível de concordância Kappa entre as enfermeiras foi excelente para a maioria das áreas de cuidado (69,0%). Concluiu-se que houve consenso e concordância das enfermeiras quanto ao instrumento ser completo, de fácil entendimento e aplicável, porém despende muito tempo. As enfermeiras reconhecem a importância do instrumento para o dimensionamento dos profissionais, organização e planejamento do cuidado.In most maternity units, the physician classifies, evaluates, and determines which unit will receive the newborn (NB) after birth. Evaluation occurs in the delivery room, taking into consideration the following factors: birth weight, gestational age, and behaviors that define the clinical picture and disease. This observational study evaluates the reliability of an NB classification instrument. The study was conducted at the nursery of a public hospital in São Paulo. Nine nurses applied the instrument to 63 NB, with two of the nurses working simultaneously in each of the nursery’s fi ve sectors. The Kappa level of agreement among the nurses was found to be excellent for most care areas\ud (69.0%). It was concluded that there was a consensus and agreement among the\ud nurses that the instrument was complete, easy to understand and applicable, but was\ud very time consuming. The nurses recognize the instrument’s importance for the allocation of professionals, organization, and care planning.En la mayoría de las maternidades la clasificación, la evaluación y la definición de la unidad para referir el recién nacido (RN), son realizadas por el médico. La evaluación se realiza en la sala de parto, considerando: peso al nacer, edad gestacional y conductas que definen el cuadro clínico y la enfermedad. Este estudio observacional tuvo como objetivo evaluar la confiabilidad de un instrumento de clasificación del RN. Fue realizada en el servicio de neonatología de un hospital público en Sao Paulo. Nueve enfermeras\ud aplicaron el instrumento a 63 RN, siendo aplicados dos de forma simultánea en los cinco sectores de la unidad neonatal. El nivel de concordancia Kappa fue excelente para la mayoría de las áreas de atención (69,0%). Se concluyó que hubo consenso y\ud concordancia entre las enfermeras, quienes expresaron que el instrumento es completo, fácil de entender y de aplicar, pero se necesita mucho tempo. Las enfermeras reconocen la importancia de este instrumento para dimensionar el número de profesionales, la organización y la planificación de la atención

Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe

Search for Physics beyond the Standard Model in Events with Overlapping Photons and Jets

Results are reported from a search for new particles that decay into a photon and two gluons, in events with jets. Novel jet substructure techniques are developed that allow photons to be identified in an environment densely populated with hadrons. The analyzed proton-proton collision data were collected by the CMS experiment at the LHC, in 2016 at root s = 13 TeV, and correspond to an integrated luminosity of 35.9 fb(-1). The spectra of total transverse hadronic energy of candidate events are examined for deviations from the standard model predictions. No statistically significant excess is observed over the expected background. The first cross section limits on new physics processes resulting in such events are set. The results are interpreted as upper limits on the rate of gluino pair production, utilizing a simplified stealth supersymmetry model. The excluded gluino masses extend up to 1.7 TeV, for a neutralino mass of 200 GeV and exceed previous mass constraints set by analyses targeting events with isolated photons.Peer reviewe