29 research outputs found

    Danças folclóricas para jovens: uma proposta do projeto novos talentos CAPES/UFOP

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    A dança como outras manifestações da cultura corporal, é capaz de inserir o aluno no mundo em que vive de forma crítica, reconhecendo-se como agente de possível transformação, mas para tal é necessário não apenas contemplar estes conteúdos e sim vivenciá-los, interpretá-los e elaborá-los corporalmente. A oficina Danças Folclóricas oferece aos alunos de diversas escolas públicas da região de Ouro Preto e Itabirito, aulas de danças folclóricas com ritmos variados abrangendo todas as regiões brasileiras. O objetivo é proporcionar ao aluno o reconhecimento e a experimentação de suas necessidades artísticas, aprender sobre grupos que compõem a cultura brasileira, valorizando a diversidade, sendo capaz de compreender, refletir, problematizar e intervir no mundo. São realizadas aulas práticas e teóricas de danças folclóricas brasileiras com o desenvolvimento de ações pedagógicas para o reconhecimento de saberes que envolvem o folclore, noções corporais, espaciais e temporais do movimento e produções artístico-culturais. As aulas trazem aos alunos um enorme conhecimento sobre danças folclóricas brasileiras, eles estão criando novas formas de se expressar na dança e com o próprio corpo, elaborando novos movimentos a partir das experiências vividas durante as aulas e suas próprias experiências corporais. Para muitos dos alunos essa se constituiu como o primeiro acesso a aulas de dança, aspecto que entendemos como um avanço para alunos que obtiveram novas possibilidades de conhecimento em dança e cultura e se reconhecem através dela.Departamento de Educación Físic

    UTILIZAÇÃO DA TERMOGRAFIA INFRAVERMELHA NA DETERMINAÇÃO DE PROPRIEDADES TÉRMICAS DE MATERIAIS PRODUZIDOS A PARTIR DE FIBRA DE BANANEIRA

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    Por ser um dos maiores produtores mundiais de banana, o Brasil também é um grande gerador de resíduos provenientes desta cultura. Dentre os resíduos, encontra-se o engaço, que pode ser utilizado como matéria prima na fabricação de materiais reciclados, por exemplo, o papel. O papel fabricado com fibra de bananeira pode ser empregado como material de embalagens na indústria de alimentos desde que algumas de suas características sejam conhecidas. Algumas destas características referem-se às propriedades térmicas, sendo as principais: calor específico, condutividade térmica e difusividade térmica. Em meio às metodologias aplicadas para a determinação destas propriedades, tem-se a termografia infravermelha, que é capaz de determinar a temperatura superficial de objetos através da coleta de imagens captadas por uma câmera que converte a radiação emitida por este objeto em sinais elétricos, criando uma imagem térmica. O objetivo deste trabalho foi utilizar a termografia infravermelha na determinação das propriedades térmicas de materiais produzidos a partir de fibra de bananeira. Para tanto, observou-se a variação da temperatura superficial da amostra utilizando a termografia infravermelha. Foi implementado, em linguagem FORTRAN®, um algoritmo capaz de simular o decaimento da temperatura quando fornecidos valores da massa específica, calor específico, condutividade térmica e difusividade térmica do material e fluxo térmico imposto à amostra. Variaram-se os valores da condutividade térmica e calor específico, no modelo matemático, até o ajuste da curva numérica com a experimental, encontrando, respectivamente, 0,25 W/(m2.K) e 1220 J/(kg.K). A difusividade térmica foi calculada, indiretamente, sendo encontrado o valor de 6,44 x 10-7 m2/s. Conclui-se que a termografia infravermelha foi capaz de determinar as propriedades desde que alguns parâmetros sejam previamente determinados, como por exemplo, a emissividade da amostra. O modelo matemático foi fundamental como ferramenta de ajuste das curvas

    estudos artísticos

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    Crescer na intervenção e na comunicação é um dos objetivos da Revista Gama, estudos artísticos. Promove-se a comunicação, formal, dentro das regras da comunicação académica, através de textos cuja característica comum é serem escritos por artistas, sobre a obra de outros artistas. Este foi o critério base que inspirou o projeto das iniciativas associadas ao Congresso CSO (criadores sobre outras obras), que já completou seis anos de disseminação. A Revista Gama singularizou-se por convocar artistas e obras que de algum modo estariam esquecidos, desconhecidos, ou ainda pouco divulgados. Obras cuja execução tem raízes em passados mais ou menos recentes, mas que pelo excesso de discursos na contemporaneidade, não obtiveram a divulgação desejada. Este é um propósito de intervenção no conhecimento patrimonial: as obras existem, foram executadas, enriquecem o nosso património, mas há que as fazer funcionar, dar a conhecer, aos outros artistas, aos especialistas, ao grande público. Assim se reuniram neste número 6 da Revista Gama vinte e quatro artigos originais, procurando-se, na sua sequência e articulação, algumas relações de pertinência e afinidade. Olhares sobre arquivos, sobre acervos, sobre coleções, conjuntos muitas vezes fechados e em perigo de esquecimento, ou de incompreensão: uma entrada discreta que se abre para o interior de uma câmara escura, que é um espaço cheio de imagens por revelar.info:eu-repo/semantics/publishedVersio

    COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

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    Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

    Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019

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    Background Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival. Methods We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (USMR). Scenarios for 2030 represent different potential trajectories, notably including potential effects of the COVID-19 pandemic and the potential impact of improvements preferentially targeting neonatal survival. Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index. Findings Global U5MR decreased from 71.2 deaths per 1000 livebirths (95% uncertainty interval WI] 68.3-74-0) in 2000 to 37.1 (33.2-41.7) in 2019 while global NMR correspondingly declined more slowly from 28.0 deaths per 1000 live births (26.8-29-5) in 2000 to 17.9 (16.3-19-8) in 2019. In 2019,136 (67%) of 204 countries had a USMR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030,154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. Deaths of children younger than 5 years totalled 9.65 million (95% UI 9.05-10.30) in 2000 and 5.05 million (4.27-6.02) in 2019, with the neonatal fraction of these deaths increasing from 39% (3.76 million 95% UI 3.53-4.021) in 2000 to 48% (2.42 million; 2.06-2.86) in 2019. NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0.80 (95% UI 0.71-0.86) deaths per 1000 livebirths and U5MR to 1.44 (95% UI 1-27-1.58) deaths per 1000 livebirths, and in 2019, there were as many as 1.87 million (95% UI 1-35-2.58; 37% 95% UI 32-43]) of 5.05 million more deaths of children younger than 5 years than the survival potential frontier. Interpretation Global child mortality declined by almost half between 2000 and 2019, but progress remains slower in neonates and 65 (32%) of 204 countries, mostly in sub-Saharan Africa and south Asia, are not on track to meet either SDG 3.2 target by 2030. Focused improvements in perinatal and newborn care, continued and expanded delivery of essential interventions such as vaccination and infection prevention, an enhanced focus on equity, continued focus on poverty reduction and education, and investment in strengthening health systems across the development spectrum have the potential to substantially improve USMR. Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

    Use of trigger tool to identify Adverse Drugs Events in dogs.

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    The highlight of the shortcomings in the regulation and surveillance of veterinary drugs in Brazil is the absence of a system to report adverse drug events (ADEs). The aim of this study was evaluate the use of triggers in dogs to detect ADEs by estimating the prevalence of ADE and identifying the possible triggers. We screened medical records for ADEs and degree of harm caused by an ADE, using known triggers, with the Global Trigger Tool: translated, adapted and validated for use in animal health. The triggers comprised two-fold increase in blood urea nitrogen or serum creatinine levels compared to baseline, administration of vitamin K, administration of diphenhydramine or promethazine, excessive sedation or hypotension, administration of an antiemetic, abrupt cessation of medication, or others. The association between the occurrence of ADEs and variables, such as age, race, duration of hospitalization, polypharmacy, and clinical outcome was evaluated. A total of 148 medical records were analyzed. The trigger tools identified the known triggers 109 times in 68 medical records. Additionally, 14 ADEs were identified; the prevalence of ADEs was 9.5%. Positive predictive values of the triggers were 12.8%, and “vitamin K administration” had the best performance. The duration of hospitalization (p-value = 0.030) and polypharmacy (p-value < 0.001) were associated with the occurrence of ADEs. Approximately 46% of the hospitalized dogs presented with at least one trigger. One out of five hospitalized dogs suffered from temporary harm due to an ADE. The duration of hospitalization and polypharmacy were found to be risk factors for ADEs in dogs

    Gasdermin-D activation by SARS-CoV-2 triggers NET and mediate COVID-19 immunopathology

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    Abstract: Background: The release of neutrophil extracellular traps (NETs) is associated with inflammation, coagulopathy, and organ damage found in severe cases of COVID-19. However, the molecular mechanisms underlying the release of NETs in COVID-19 remain unclear. Objectives: We aim to investigate the role of the Gasdermin-D (GSDMD) pathway on NETs release and the development of organ damage during COVID-19. Methods: We performed a single-cell transcriptome analysis in public data of bronchoalveolar lavage. Then, we enrolled 63 hospitalized patients with moderate and severe COVID-19. We analyze in blood and lung tissue samples the expression of GSDMD, presence of NETs, and signaling pathways upstreaming. Furthermore, we analyzed the treatment with disulfiram in a mouse model of SARS-CoV-2 infection. Results: We found that the SARS-CoV-2 virus directly activates the pore-forming protein GSDMD that triggers NET production and organ damage in COVID-19. Single-cell transcriptome analysis revealed that the expression of GSDMD and inflammasome-related genes were increased in COVID-19 patients. High expression of active GSDMD associated with NETs structures was found in the lung tissue of COVID-19 patients. Furthermore, we showed that activation of GSDMD in neutrophils requires active caspase1/4 and live SARS-CoV-2, which infects neutrophils. In a mouse model of SARS-CoV-2 infection, the treatment with disulfiram inhibited NETs release and reduced organ damage. Conclusion: These results demonstrated that GSDMD-dependent NETosis plays a critical role in COVID-19 immunopathology and suggests GSDMD as a novel potential target for improving the COVID-19 therapeutic strategy
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