545 research outputs found

    FORMAÇÃO DE COMPETÊNCIAS DO ADMINISTRADOR: ANÁLISE DA PERCEPÇÃO DOS CONCLUINTES E EGRESSOS DO CURSO DE GRADUAÇÃO

    Get PDF
    O presente trabalho tem como objetivo principal o diagnóstico das competências dos acadêmicos formandos em Administração de uma Instituição de Ensino Superior (IES). Fundamentado na literatura sobre competências profissionais, buscou-se conhecer as competências desenvolvidas no curso de Administração em relação às requeridas no ambiente profissional, na percepção do formando. A pesquisa de caráter exploratória e descritiva teve etapas qualitativas e quantitativas, com características de método de triangulação de dados. Para tanto, desenvolveu-se pesquisa documental no projeto pedagógico do curso de Administração para identificar as práticas pedagógicas que proporcionam o desenvolvimento de competências. A etapa quantitativa compreendeu uma survey com os 82 discentes concluindo o curso de Administração (7º e 8º períodos), tendo como base as competências estipuladas como importantes ao perfil do egresso do curso de Administração segundo as Diretrizes Curriculares Nacionais do MEC. A etapa qualitativa desenvolveu-se com entrevista em profundidade com dois egressos do curso de administração. Realizou-se a análise quanto ao nível requerido das competências no ambiente profissional do discente e do desenvolvimento das mesmas no curso de Graduação. Observou-se que as competências desenvolvidas no curso de administração estão em consonância com as requeridas no ambiente de trabalho, sob a percepção do acadêmico, embora hajam competências desenvolvidas em menor escala que o requerido

    Early, Chronic, and Acute Cannabis Exposure and Their Relationship With Cognitive and Behavioral Harms

    Get PDF
    Background: Cannabis is the third most consumed drug worldwide. Thus, healthcare providers should be able to identify users who are in need for an intervention. This study aims to explore the relationship of acute, chronic, and early exposure (AE, CE, and EE) to cannabis with cognitive and behavioral harms (CBH), as a first step toward defining risky cannabis use criteria. Methods: Adults living in Spain who used cannabis at least once during the last year answered an online survey about cannabis use and health-related harms. Cannabis use was assessed in five dimensions: quantity on use days during the last 30 days (AE), frequency of use in the last month (AE), years of regular use (YRCU) (CE), age of first use (AOf) (EE), and age of onset of regular use (AOr) (EE). CBH indicators included validated instruments and custom-made items. Pearson correlations were calculated for continuous variables, and Student’s t-tests for independent samples were calculated for categorical variables. Effect sizes were calculated for each of the five dimensions of use (Cohen’s d or r Pearson correlation) and harm outcome. Classification and Regression Trees (CART) analyses were performed for those dependent variables (harms) significantly associated with at least two dimensions of cannabis use patterns. Lastly, logistic binary analyses were conducted for each harm outcome. Results: The mean age of participants was 26.2 years old [standard deviation (SD) 8.5]. Out of 2,124 respondents, 1,606 (75.6%) reported at least one harm outcome (mean 1.8 and SD 1.5). In our sample, using cannabis on 3 out of 4 days was associated with an 8-fold probability of scoring 4+ on the Severity Dependence Scale (OR 8.33, 95% CI 4.91–14.16, p < 0.001), which is indicative of a cannabis use disorder. Also, a start of regular cannabis use before the age of 25 combined with using cannabis at least once per month was associated with a higher probability of risky alcohol use (OR 1.33, 95% CI 1.12–1.57, p = 0.001). Besides, a start of regular cannabis use before the age of 18 combined with a period of regular use of at least 7.5 years was associated with a higher probability of reporting a motor vehicle accident (OR 1.81, 95% CI 1.41–2.32, p < 0.0001). Results were ambiguous regarding the role that age of first use and milligrams of THC per day of use might play regarding cannabis-related harms. Conclusions: The relationship among AE, CE, and EE with CBH indicators is a complex phenomenon that deserves further studies. The pattern of cannabis use should be carefully and widely evaluated—(not just including frequency but also other dimensions of pattern of use)—in research (preferably in longitudinal studies) to assess cannabis-related harms

    A global agenda for advancing freshwater biodiversity research

    Get PDF
    Global freshwater biodiversity is declining dramatically, and meeting the challenges of this crisis requires bold goals and the mobilisation of substantial resources. While the reasons are varied, investments in both research and conservation of freshwater biodiversity lag far behind those in the terrestrial and marine realms. Inspired by a global consultation, we identify 15 pressing priority needs, grouped into five research areas, in an effort to support informed stewardship of freshwater biodiversity. The proposed agenda aims to advance freshwater biodiversity research globally as a critical step in improving coordinated actions towards its sustainable management and conservation

    International Federation for Emergency Medicine model curriculum for medical student education in emergency medicine

    Get PDF
    There is a critical and growing need for emergency physicians and emergency medicine resources worldwide. To meet this need, physicians must be trained to deliver time-sensitive interventions and life-saving emergency care. Currently, there is no internationally recognized, standard curriculum that defines the basic minimum standards for emergency medicine education. To address this lack, the International Federation for Emergency Medicine (IFEM) convened a committee of international physicians, health professionals, and other experts in emergency medicine and international emergency medicine development to outline a curriculum for foundation training of medical students in emergency medicine. This curriculum document represents the consensus of recommendations by this committee. The curriculum is designed with a focus on the basic minimum emergency medicine educational content that any medical school should be delivering to its students during their undergraduate years of training. It is not designed to be prescriptive, but to assist educators and emergency medicine leadership in advancing physician education in basic emergency medicine content. The content would be relevant, not just for communities with mature emergency medicine systems, but also for developing nations or for nations seeking to expand emergency medicine within current educational structures. We anticipate that there will be wide variability in how this curriculum is implemented and taught, reflecting the existing educational milieu, the resources available, and the goals of the institutions’ educational leadership

    Modeling Spanish anxiolytic consumption: Economic, demographic and behavioral influences

    Full text link
    Anxiolytics (AX) are the psychotropic drugs prescribed for the treatment of anxiety and insomnia for 2–4 weeks, for longer periods of consumption (>1 month) may lead to the development of tolerance or addiction. In fact, its prescription was 16% of the total pharmaceutical expenditure in Spain in 2007. This paper deals with the development of a mathematical model describing the dynamic of the addiction to AX for the case study of the Spanish region of Castellón. The reasons believed to cause the development of addicts to AX are the economic situation, the marriage termination and the social contact. The simulations performed to forecast the addicts rate for the period 2010–2014 showed an increase from 6% in 2010 to 14% in 2014 with a fluctuation of about 2% between the possible economic scenarios. Finally, the analysis of sensitivity of the rate of addicts to the fluctuation of the social contact parameters was performed, letting us estimate its impact on the pharmaceutical expenditure.De La Poza, E.; Guadalajara Olmeda, MN.; Jódar Sánchez, LA.; Merello Giménez, P. (2013). Modeling Spanish anxiolytic consumption: Economic, demographic and behavioral influences. Mathematical and Computer Modelling. 57(7):1619-1624. https://doi.org/10.1016/j.mcm.2011.10.020S1619162457

    Numerical Simulations of Gravity-Driven Fingering in Unsaturated Porous Media Using a Non-Equilibrium Model

    Get PDF
    This is a computational study of gravity-driven fingering instabilities in unsaturated porous media. The governing equations and corresponding numerical scheme are based on the work of Nieber et al. [Ch. 23 in Soil Water Repellency, eds. C. J. Ritsema and L. W. Dekker, Elsevier, 2003] in which non-monotonic saturation profiles are obtained by supplementing the Richards equation with a non-equilibrium capillary pressure-saturation relationship, as well as including hysteretic effects. The first part of the study takes an extensive look at the sensitivity of the finger solutions to certain key parameters in the model such as capillary shape parameter, initial saturation, and capillary relaxation coefficient. The second part is a comparison to published experimental results that demonstrates the ability of the model to capture realistic fingering behaviour

    NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells

    Get PDF
    Dysregulation of inflammatory responses is a hallmark of multiple diseases such as atherosclerosis and rheumatoid arthritis. As constitutively active transcription factors, NR4A nuclear receptors function to control the magnitude of inflammatory responses and in chronic inflammatory disease can be protective or pathogenic. Within this study, we demonstrate that TLR4 stimulation using the endotoxin lipopolysaccharide (LPS) rapidly enhances NR4A1–3 expression in human and murine, primary and immortalized myeloid cells with concomitant gene transcription and protein secretion of MIP-3α, a central chemokine implicated in numerous pathologies. Deficiency of NR4A2 and NR4A3 in human and murine myeloid cells reveals that both receptors function as positive regulators of enhanced MIP-3α expression. In contrast, within the same cell types and conditions, altered NR4A activity leads to suppression of LPS-induced MCP-1 gene and protein expression. An equivalent pattern of inflammatory gene regulation is replicated in TNFα-treated myeloid cells. We show that NF-κB is the critical regulator of NR4A1–3, MIP-3α, and MCP-1 during TLR4 stimulation in myeloid cells and highlight a parallel mechanism whereby NR4A activity can repress or enhance NF-κB target gene expression simultaneously. Mechanistic insight reveals that NR4A2 does not require DNA-binding capacity in order to enhance or repress NF-κB target gene expression simultaneously and establishes a role for NF-κB family member Relb as a novel NR4A target gene involved in the positive regulation of MIP-3α. Thus, our data reveal a dynamic role for NR4A receptors concurrently enhancing and repressing NF-κB activity in myeloid cells leading to altered transcription of key inflammatory mediators

    Use of eco-friendly epoxy resins from renewable resources as potential substitutes of petrochemical epoxy resins for ambient cured composites with flax reinforcements

    Full text link
    [EN] In the last years, some high renewable content epoxy resins, derived from vegetable oils, have been developed at industrial level and are now commercially available; these can compete with petroleum-based resins as thermoset matrices for composite materials. Nevertheless, due to the relatively high cost in comparison to petroleum-based resins, their use is still restricted to applications with relatively low volume consumption such as model making, tuning components, nautical parts, special effects, outdoor sculptures, etc. in which, the use of composite laminates with carbon, aramid and, mainly, glass fibers is generalized by using hand layup and vacuum assisted resin transfer molding (VARTM) techniques due to low manufacturing costs and easy implementation. In this work, we study the behavior of two high renewable content epoxy resins derived from vegetable oils as potential substitutes of petroleum-based epoxies in composite laminates with flax reinforcements by using the VARTM technique. The curing behavior of the different epoxy resins is compared in terms of the gel point and exothermicity profile by differential scanning calorimetry (DSC). In addition, overall performance of flax-epoxy composites is compared with standardized mechanical (tensile, flexural and impact) and thermal (Vicat softening temperature, heat deflection temperature, thermo-mechanical analysis) tests. The curing DSC profiles of the two eco-friendly epoxy resins are similar to a conventional epoxy resin. They can be easily handled and processed by conventional VARTM process thus leading to composite laminates with flax with balanced mechanical and thermal properties, similar or even higher to a multipurpose epoxy resin. © 2012 Society of Plastics Engineers.This work is part of the project IPT-310000-2010-037, "ECOTEXCOMP: Research and development of textile structures useful as reinforcement of composite materials with marked ecological character" funded by the "Ministerio de Ciencia e Innovacion", with an aid of 189540.20 euros, within the "Plan Nacional de Investigacion Cientifica, Desarrollo e InnovacionTecnologica 2008-2011" and funded by the European Union through FEDER funds, Technology Fund 2007-2013, Operational Programme on R+D+i for and on behalf of the companies."Bertomeu Perelló, D.; García Sanoguera, D.; Fenollar Gimeno, OÁ.; Boronat Vitoria, T.; Balart Gimeno, RA. (2012). Use of eco-friendly epoxy resins from renewable resources as potential substitutes of petrochemical epoxy resins for ambient cured composites with flax reinforcements. Polymer Composites. 33(5):683-692. https://doi.org/10.1002/pc.22192S683692335Alves, C., Ferrão, P. M. C., Silva, A. J., Reis, L. G., Freitas, M., Rodrigues, L. B., & Alves, D. E. (2010). Ecodesign of automotive components making use of natural jute fiber composites. Journal of Cleaner Production, 18(4), 313-327. doi:10.1016/j.jclepro.2009.10.022JOHN, M., & THOMAS, S. (2008). Biofibres and biocomposites. Carbohydrate Polymers, 71(3), 343-364. doi:10.1016/j.carbpol.2007.05.040Mohanty, A. K., Misra, M., & Drzal, L. T. (2002). Journal of Polymers and the Environment, 10(1/2), 19-26. doi:10.1023/a:1021013921916Pillin, I., Kervoelen, A., Bourmaud, A., Goimard, J., Montrelay, N., & Baley, C. (2011). Could oleaginous flax fibers be used as reinforcement for polymers? Industrial Crops and Products, 34(3), 1556-1563. doi:10.1016/j.indcrop.2011.05.016Summerscales, J., Dissanayake, N. P. J., Virk, A. S., & Hall, W. (2010). A review of bast fibres and their composites. Part 1 – Fibres as reinforcements. Composites Part A: Applied Science and Manufacturing, 41(10), 1329-1335. doi:10.1016/j.compositesa.2010.06.001Sreekumar, P. A., Saiah, R., Saiter, J. M., Leblanc, N., Joseph, K., Unnikrishnan, G., & Thomas, S. (2009). Dynamic mechanical properties of sisal fiber reinforced polyester composites fabricated by resin transfer molding. Polymer Composites, 30(6), 768-775. doi:10.1002/pc.20611Mu, Q., Wei, C., & Feng, S. (2009). Studies on mechanical properties of sisal fiber/phenol formaldehyde resin in-situ composites. Polymer Composites, 30(2), 131-137. doi:10.1002/pc.20529Sever, K., Sarikanat, M., Seki, Y., Erkan, G., Erdoğan, Ü. H., & Erden, S. (2012). Surface treatments of jute fabric: The influence of surface characteristics on jute fabrics and mechanical properties of jute/polyester composites. Industrial Crops and Products, 35(1), 22-30. doi:10.1016/j.indcrop.2011.05.020Wood, B. M., Coles, S. R., Maggs, S., Meredith, J., & Kirwan, K. (2011). Use of lignin as a compatibiliser in hemp/epoxy composites. Composites Science and Technology, 71(16), 1804-1810. doi:10.1016/j.compscitech.2011.06.005Eichhorn, S. J., Baillie, C. A., Zafeiropoulos, N., Mwaikambo, L. Y., Ansell, M. P., Dufresne, A., … Wild, P. M. (2001). Journal of Materials Science, 36(9), 2107-2131. doi:10.1023/a:1017512029696Dissanayake, N. P. J., Summerscales, J., Grove, S. M., & Singh, M. M. (2009). Life Cycle Impact Assessment of Flax Fibre for the Reinforcement of Composites. Journal of Biobased Materials and Bioenergy, 3(3), 245-248. doi:10.1166/jbmb.2009.1029Masudul Hassan, M., & Khan, M. A. (2008). Role of N-(β-amino ethyl) γ-aminopropyl trimethoxy silane as Coupling Agent on the Jute-polycarbonate Composites. Polymer-Plastics Technology and Engineering, 47(8), 847-850. doi:10.1080/03602550802188862Zaman, H. U., Khan, M. A., & Khan, R. A. (2009). Improvement of Mechanical Properties of Jute Fibers-Polyethylene/Polypropylene Composites: Effect of Green Dye and UV Radiation. Polymer-Plastics Technology and Engineering, 48(11), 1130-1138. doi:10.1080/03602550903147262Zou, Y., Xu, H., & Yang, Y. (2010). Lightweight Polypropylene Composites Reinforced by Long Switchgrass Stems. Journal of Polymers and the Environment, 18(4), 464-473. doi:10.1007/s10924-010-0165-4De Arcaya, P. A., Retegi, A., Arbelaiz, A., Kenny, J. M., & Mondragon, I. (2009). Mechanical properties of natural fibers/polyamides composites. Polymer Composites, 30(3), 257-264. doi:10.1002/pc.20558Twite-Kabamba, E., Mechraoui, A., & Rodrigue, D. (2009). Rheological properties of polypropylene/hemp fiber composites. Polymer Composites, 30(10), 1401-1407. doi:10.1002/pc.20704De Rosa, I. M., Iannoni, A., Kenny, J. M., Puglia, D., Santulli, C., Sarasini, F., & Terenzi, A. (2011). Poly(lactic acid)/Phormium tenax composites: Morphology and thermo-mechanical behavior. Polymer Composites, 32(9), 1362-1368. doi:10.1002/pc.21159Christian, S. J., & Billington, S. L. (2011). Mechanical response of PHB- and cellulose acetate natural fiber-reinforced composites for construction applications. Composites Part B: Engineering, 42(7), 1920-1928. doi:10.1016/j.compositesb.2011.05.039Hodzic, A., Coakley, R., Curro, R., Berndt, C. C., & Shanks, R. A. (2007). Design and Optimization of Biopolyester Bagasse Fiber Composites. Journal of Biobased Materials and Bioenergy, 1(1), 46-55. doi:10.1166/jbmb.2007.005Bax, B., & Müssig, J. (2008). Impact and tensile properties of PLA/Cordenka and PLA/flax composites. Composites Science and Technology, 68(7-8), 1601-1607. doi:10.1016/j.compscitech.2008.01.004Leite, M. C. A. M., Furtado, C. R. G., Couto, L. O., Oliveira, F. L. B. O., & Correia, T. R. (2010). Avaliação da biodegradação de compósitos de poli(ε-caprolactona)/fibra de coco verde. Polímeros, 20(5), 339-344. doi:10.1590/s0104-14282010005000063Saiah, R., Sreekumar, P. A., Gopalakrishnan, P., Leblanc, N., Gattin, R., & Saiter, J. M. (2009). Fabrication and characterization of 100% green composite: Thermoplastic based on wheat flour reinforced by flax fibers. Polymer Composites, 30(11), 1595-1600. doi:10.1002/pc.20732Campaner, P., D’Amico, D., Longo, L., Stifani, C., & Tarzia, A. (2009). Cardanol-based novolac resins as curing agents of epoxy resins. Journal of Applied Polymer Science, 114(6), 3585-3591. doi:10.1002/app.30979Raju, & Kumar, P. (2011). Cathodic electrodeposition of self-curable polyepoxide resins based on cardanol. Journal of Coatings Technology and Research, 8(5), 563-575. doi:10.1007/s11998-011-9337-yRao, B. S., & Palanisamy, A. (2011). Monofunctional benzoxazine from cardanol for bio-composite applications. Reactive and Functional Polymers, 71(2), 148-154. doi:10.1016/j.reactfunctpolym.2010.11.025Chen, L., Zhou, S., Song, S., Zhang, B., & Gu, G. (2010). Preparation and anticorrosive performances of polysiloxane-modified epoxy coatings based on polyaminopropylmethylsiloxane-containing amine curing agent. Journal of Coatings Technology and Research, 8(4), 481-487. doi:10.1007/s11998-010-9311-0Ghosh, K., Garcia, P., & Galgoci, E. (1999). Recent advances in epoxy curing agent technology for low temperature cure coatings. Anti-Corrosion Methods and Materials, 46(2), 100-110. doi:10.1108/00035599910263215Seniha Güner, F., Yağcı, Y., & Tuncer Erciyes, A. (2006). Polymers from triglyceride oils. Progress in Polymer Science, 31(7), 633-670. doi:10.1016/j.progpolymsci.2006.07.001Tsujimoto, T., Uyama, H., & Kobayashi, S. (2010). Synthesis of high-performance green nanocomposites from renewable natural oils. Polymer Degradation and Stability, 95(8), 1399-1405. doi:10.1016/j.polymdegradstab.2010.01.016Gupta, A. P., Ahmad, S., & Dev, A. (2011). Modification of novel bio-based resin-epoxidized soybean oil by conventional epoxy resin. Polymer Engineering & Science, 51(6), 1087-1091. doi:10.1002/pen.21791Manthey, N. W., Cardona, F., Aravinthan, T., & Cooney, T. (2011). Cure kinetics of an epoxidized hemp oil based bioresin system. Journal of Applied Polymer Science, 122(1), 444-451. doi:10.1002/app.34086Mustata, F., Tudorachi, N., & Rosu, D. (2011). Curing and thermal behavior of resin matrix for composites based on epoxidized soybean oil/diglycidyl ether of bisphenol A. Composites Part B: Engineering, 42(7), 1803-1812. doi:10.1016/j.compositesb.2011.07.003Takahashi, T., Hirayama, K., Teramoto, N., & Shibata, M. (2008). Biocomposites composed of epoxidized soybean oil cured with terpene-based acid anhydride and cellulose fibers. Journal of Applied Polymer Science, 108(3), 1596-1602. doi:10.1002/app.27866Miyagawa, H., Misra, M., Drzal, L. T., & Mohanty, A. K. (2005). Fracture toughness and impact strength of anhydride-cured biobased epoxy. Polymer Engineering & Science, 45(4), 487-495. doi:10.1002/pen.20290J. D. Espinoza Pérez, D. M. Haagenson, S. W. Pryor, C. A. Ulven, & D. P. Wiesenborn. (2009). Production and Characterization of Epoxidized Canola Oil. Transactions of the ASABE, 52(4), 1289-1297. doi:10.13031/2013.27772Morye, S. S., & Wool, R. P. (2005). Mechanical properties of glass/flax hybrid composites based on a novel modified soybean oil matrix material. Polymer Composites, 26(4), 407-416. doi:10.1002/pc.20099Thielemans, W., & Wool, R. P. (2005). Kraft lignin as fiber treatment for natural fiber-reinforced composites. Polymer Composites, 26(5), 695-705. doi:10.1002/pc.20141Abdelkader, A. F., & White, J. R. (2005). Water absorption in epoxy resins: The effects of the crosslinking agent and curing temperature. Journal of Applied Polymer Science, 98(6), 2544-2549. doi:10.1002/app.22400Astruc, A., Joliff, E., Chailan, J.-F., Aragon, E., Petter, C. O., & Sampaio, C. H. (2009). Incorporation of kaolin fillers into an epoxy/polyamidoamine matrix for coatings. Progress in Organic Coatings, 65(1), 158-168. doi:10.1016/j.porgcoat.2008.11.00

    Neutral Hydrogen Gas in Interacting Galaxies: The NGC 1511 galaxy group

    Full text link
    We present HI line and 20-cm radio continuum observations of the NGC 1511 galaxy group obtained with the Australia Telescope Compact Array. The data reveal an extended, rather disturbed HI distribution for the peculiar starburst galaxy NGC 1511 and a narrow bridge to its small companion galaxy, NGC 1511B, which has been severely distorted by the interaction/collision between the two galaxies. No stellar counterpart to the gaseous bridge has been detected. In addition, we find that the peculiar optical ridge to the east of NGC 1511 is probably the stellar remnant of a galaxy completed disrupted by interactions with NGC 1511. The slightly more distant neighbour, NGC 1511A, shows a regular HI velocity field and no obvious signs of interactions. Radio continuum emission from NGC 1511 reveals three prominent sources on top of a more diffuse, extended distribution. We derive an overall star formation rate of 7 Msun/yr. The most enhanced star formation is found in the south-eastern part of the disk, coincident with several bright HII regions, and closest to the peculiar optical ridge. No continuum emission was detected in the companions, but NGC 1511B appears to show an HII region at its faint western edge, closest to NGC 1511. The group displays a prime example of interaction-induced star formation activity.Comment: 9 pages, 8 figures, accepted for publication in MNRA
    corecore