Association of Painful musculoskeletal conditions and migraine headache with mental and sleep disorders among adults with disabilities, Spain, 2007-2008.

Introduction: The aim of the study was to determine the prevalence of musculoskeletal painful conditions and migraine/headache in a population with disabilities, and their association with anxiety, depression and sleep disorders. Methods: This cross-sectional study analyzed data from the Spanish Disability-Dependence Survey on 16932 subjects ≥18 years-of-age that suffer disabilities. The prevalence (CI 95%) of musculoskeletal painful conditions was considered through the diagnosis of arthritis, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscular dystrophy and neck or back pain. The prevalence of migraine/headache was also calculated. Factors associated to these painful conditions were analyzed separately for each sex using a logistic regression model. Results: The prevalence of musculoskeletal painful conditions was 66.9% (CI 95%: 66.2-67.6) and that of migraine/headache was 23.4% (CI95%:22.8-24.1), both of which were higher in women than in men. Factors associated to these painful conditions in both men and women included increased age, sleeping less than 6 hours, and concomitant chronic anxiety and/or depression. Conclusion: The prevalence of musculoskeletal painful conditions and migraine/headache is high in individuals with disability in Spain, especially in women, and these conditions often coexist with depression, anxiety and/or sleep disturbances. Our findings suggest that mental and/or sleep disorders should be considered alongside conventional treatments in subjects with disability and specific painful conditions in order to design effective programs to rehabilitate them and improve their quality of life

The muon g-2 in a SU(7) left-right symmetric model with mirror fermions

We have studied a left-right symmetric model with mirror fermions based in a grand unified SU(7) model in order to account for the muon anomaly. The Higgs sector of the model contains two Higgs doublets and the hierarchy condition $\upsilon_{L}\ll\upsilon_{R}$ can be achieved by using two additional Higgs singlets, one even and other odd under $\mathcal{D}$-parity. We show that there is a wide range of values for the mass parameters of the model that is consistent with the $g-2$ lepton anomalies. Radiative correction to the mass of the ordinary fermions are shown to be small

Weak Magnetic Dipole Moments in the MSSM

We calculate the weak magnetic dipole moment of different fermions in the MSSM. In particular, we consider in detail the predictions for the WMDM of the tau lepton and bottom quark. We compare the purely SUSY contributions with two Higss doublet models and SM predictions. For the tau lepton, we show that chargino diagrams give the main SUSY contribution, which for tan beta=50 can be one order of magnitude bigger than the SM prediction. For the b quark, gluino diagrams provide the main SUSY contribution to its weak anomalous dipole moment, which is still dominated by gluon contributions. We also study how the universality assumption in the slepton sector induces correlations between the SUSY contributions to the tau WMDM and to (g-2) of the muon.Comment: 17 pages, LaTex, uses psfig.sty with 6 figure

Dark Force Detection in Low Energy e-p Collisions

We study the prospects for detecting a light boson X with mass m_X < 100 MeV at a low energy electron-proton collider. We focus on the case where X dominantly decays to e+ e- as motivated by recent "dark force" models. In order to evade direct and indirect constraints, X must have small couplings to the standard model (alpha_X 10 MeV). By comparing the signal and background cross sections for the e- p e+ e- final state, we conclude that dark force detection requires an integrated luminosity of around 1 inverse attobarn, achievable with a forthcoming JLab proposal.Comment: 38 pages, 19 figures; v2, references adde

Constraints from muon g-2 and LFV processes in the Higgs Triplet Model

Constraints from the muon anomalous magnetic dipole moment and lepton flavor violating processes are translated into lower bounds on v_Delta*m_H++ in the Higgs Triplet Model by considering correlations through the neutrino mass matrix. The discrepancy of the sign of the contribution to the muon anomalous magnetic dipole moment between the measurement and the prediction in the model is clarified. It is shown that mu to e gamma, tau decays (especially, tau to mu e e), and the muonium conversion can give a more stringent bound on v_Delta*m_H++ than the bound from mu to eee which is expected naively to give the most stringent one.Comment: 18 pages, 16 figure

Associated Charm Production in Neutrino-Nucleus Interactions

In this paper a search for associated charm production both in neutral and charged current $\nu$-nucleus interactions is presented. The improvement of automatic scanning systems in the {CHORUS} experiment allows an efficient search to be performed in emulsion for short-lived particles. Hence a search for rare processes, like the associated charm production, becomes possible through the observation of the double charm-decay topology with a very low background. About 130,000 $\nu$ interactions located in the emulsion target have been analysed. Three events with two charm decays have been observed in the neutral-current sample with an estimated background of 0.18$\pm$0.05. The relative rate of the associated charm cross-section in deep inelastic $\nu$ interactions, $\sigma(c\bar{c}\nu)/\sigma_\mathrm{NC}^\mathrm{DIS}= (3.62^{+2.95}_{-2.42}({stat})\pm 0.54({syst}))\times 10^{-3}$ has been measured. One event with two charm decays has been observed in charged-current $\nu_\mu$ interactions with an estimated background of 0.18$\pm$0.06 and the upper limit on associated charm production in charged-current interactions at 90% C.L. has been found to be $\sigma (c\bar{c} \mu^-)/\sigma_\mathrm{CC} < 9.69 \times 10^{-4}$.Comment: 10 pages, 4 figure

The Muon Anomalous Magnetic Moment: A Harbinger For "New Physics"

QED, Hadronic, and Electroweak Standard Model contributions to the muon anomalous magnetic moment, a_mu = (g_mu-2)/2, and their theoretical uncertainties are scrutinized. The status and implications of the recently reported 2.6 sigma experiment vs.theory deviation a_mu^{exp}-a_mu^{SM} = 426(165) times 10^{-11} are discussed. Possible explanations due to supersymmetric loop effects with m_{SUSY} \simeq 55 sqrt{tan beta} GeV, radiative mass mechanisms at the 1--2 TeV scale and other ``New Physics'' scenarios are examined.Comment: 24 page

The influence of synaptic activity on neuronal health

According to the theory of neuronal health, neurons exist in a spectrum of states ranging from highly resilient to vulnerable. An unhealthy neuron may be rendered dysfunctional or non-viable by an insult that would ordinarily be non-toxic to a healthy neuron. Over the years it has become clear that a neuron’s health is subject to dynamic regulation by electrical or synaptic activity. This review highlights recently identified activity dependent signalling events which boost neuronal health through the transcriptional control of pro- and anti-apoptotic genes, the enhancement of antioxidant defences, and the regulation of mitochondrial and neurotrophic factor availability. Furthermore, activity dependent signals have recently been shown to influence a variety of events specific to individual neurodegenerative diseases, which will also be highlighted

Gender differences in health of EU10 and EU15 populations: the double burden of EU10 men

This study compares gender differences in Healthy Life Years (HLY) and unhealthy life years (ULY) between the original (EU15) and new member states (EU10). Based on the number of deaths, population and prevalence of activity limitations from the Statistics of Living and Income Conditions Survey (SILC) survey, we calculated HLY and ULY for the EU10 and EU15 in 2006 with the Sullivan method. We used decomposition analysis to assess the contributions of mortality and disability and age to gender differences in HLY and ULY. HLY at age 15 for women in the EU10 were 3.1 years more than those for men at the same age, whereas HLY did not differ by gender in the EU15. In both populations ULY at age 15 for women exceeded those for men by 5.5 years. Decomposition showed that EU10 women had more HLY because higher disability in women only partially offset (−0.8 years) the effect of lower mortality (+3.9 years). In the EU15 women’s higher disability prevalence almost completely offset women’s lower mortality. The 5.3 fewer ULY in EU10 men than in EU10 women mainly reflected higher male mortality (4.5 years), while the fewer ULY in EU15 men than in EU15 women reflected both higher male mortality (2.9 years) and higher female disability (2.6 years). The absence of a clear gender gap in HLY in the EU15 thus masked important gender differences in mortality and disability. The similar size of the gender gap in ULY in the EU-10 and EU-15 masked the more unfavourable health situation of EU10 men, in particular the much stronger and younger mortality disadvantage in combination with the virtually absent disability advantage below age 65 in men

Controlled production of atomic oxygen and nitrogen in a pulsed radio-frequency atmospheric-pressure plasma

International audienceRadio-frequency driven atmospheric pressure plasmas are efficient sources for the production of reactive species at ambient pressure and close to room temperature. Pulsing the radio-frequency power input provides additional control over species production and gas temperature. Here, we demonstrate the controlled production of highly reactive atomic oxygen and nitrogen in a pulsed radio-frequency ( ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn001.gif] 13.56 MHz) atmospheric-pressure plasma, operated with a small ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn002.gif] 0.1 % air-like admixture ( ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn003.gif] \rm N_2 / ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn004.gif] \rm O_2 at ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn005.gif] 4:1 ) through variations in the duty cycle. Absolute densities of atomic oxygen and nitrogen are determined through vacuum-ultraviolet absorption spectroscopy using the DESIRS beamline at the SOLEIL synchrotron coupled with a high resolution Fourier-transform spectrometer. The neutral-gas temperature is measured using nitrogen molecular optical emission spectroscopy. For a fixed applied-voltage amplitude (234?V), varying the pulse duty cycle from 10% to 100% at a fixed 10?kHz pulse frequency enables us to regulate the densities of atomic oxygen and nitrogen over the ranges of ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn006.gif] (0.18±0.03) ? ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn007.gif] (3.7±0.1)× 10^20 ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn008.gif] \rm m^-3 and ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn009.gif] (0.2±0.06) ? ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn010.gif] (4.4±0.8) × 10^19 ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn011.gif] \rm m^-3 , respectively. The corresponding 11?K increase in the neutral-gas temperature with increased duty cycle, up to a maximum of ##IMG## [http://ej.iop.org/images/0022-3727/50/45/455204/daa8da2ieqn012.gif] (314±4) K, is relatively small. This additional degree of control, achieved through regulation of the pulse duty cycle and time-averaged power, could be of particular interest for prospective biomedical applications