Coherent fibre-optic link: applications in Time and Frequency metrology, Geodesy, Radio Astronomy and Seismology

L'abstract è presente nell'allegato / the abstract is in the attachmen

Synapses, Synaptic Activity and Intraneuronal Aβ in Alzheimer's Disease

β-Amyloid peptide accumulation plays a central role in the pathogenesis of Alzheimer's disease. Aberrant β-amyloid buildup in the brain has been shown to be present both in the extracellular space and within neurons. Synapses are important targets of β-amyloid, and alterations in synapses better correlate with cognitive impairment than amyloid plaques or neurofibrillary tangles. The link between β-amyloid and synapses became even tighter when it was discovered that β-amyloid accumulates within synapses and that synaptic activity modulates β-amyloid secretion. Currently, a central question in Alzheimer's disease research is what role synaptic activity plays in the disease process, and how specifically β-amyloid is involved in the synaptic dysfunction that characterizes the disease

In Reply

This response to Migliore et al. further discusses the surgical resection of patients with lung metastases from colorectal cancers

GlobVolcano Project Overview

The GlobVolcano project is part of the ESA DUE programme. The project aims at demonstrating EO-based services to support the Volcanological Observatories and other mandate users (e.g. Civil Protection authorities, scientific communities of volcanoes) in their monitoring activities. During the project a worldwide selection of user organizations will cooperate with the GlobVolcano team in order to harmonize user’s requirements and to evaluate the EO-based services . The “Osservatorio Vesuviano” of Naples (INGV-Italy) coordinates the communications between the project and the User Community. IPGP of Paris is responsible for the scientific coordination and the validation activities. The project activities are split in two phases. During the first phase (completed in June 2008) the service infrastructure and interface to the users have been developed. Prototype EO-based information products have been generated and validated. Service provision on pre-operational basis will take place during the second phase

PI and OPG/RANKL levels in human osteoblast cells

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