Constraining halo occupation properties of X-ray AGNs using clustering of Chandra sources in the Bootes survey region

We present one of the most precise measurement to date of the spatial clustering of X-ray selected AGNs using a sample derived from the Chandra X-ray Observatory survey in the Bootes field. The real-space two-point correlation function over a redshift interval from z=0.17 to z~3 is well described by the power law, xi(r)=(r/r0)^-gamma, for comoving separations r<~20h^-1 Mpc. We find gamma=1.84+-0.12 and r0 consistent with no redshift trend within the sample (varying between r0=5.5+-0.6 h^-1 Mpc for =0.37 and r0=6.9+-1.0 h^-1 Mpc for =1.28). Further, we are able to measure the projections of the two-point correlation function both on the sky plane and in the line of sight. We use these measurements to show that the Chandra/Bootes AGNs are predominantly located at the centers of dark matter halos with the circular velocity Vmax>320 km/s or M_200 > 4.1e12 h^-1 Msun, and tend to avoid satellite galaxies in halos of this or higher mass. The halo occupation properties inferred from the clustering properties of Chandra/Bootes AGNs --- the mass scale of the parent dark matter halos, the lack of significant redshift evolution of the clustering length, and the low satellite fraction --- are broadly consistent with the Hopkins et al. scenario of quasar activity triggered by mergers of similarly-sized galaxies.Comment: Accepted to ApJ. The revision matches the accepted version. The most significant changes include the recalculation of uncertainties using mock catalogs and explicit comparison with the AGN HOD studies based on projected correlation function, w(rp

A critical assessment of SELDI-TOF-MS for biomarker discovery in serum and tissue of patients with an ovarian mass

<p>Abstract</p> <p>Background</p> <p>Less than 25% of patients with a pelvic mass who are presented to a gynecologist will eventually be diagnosed with epithelial ovarian cancer. Since there is no reliable test to differentiate between different ovarian tumors, accurate classification could facilitate adequate referral to a gynecological oncologist, improving survival. The goal of our study was to assess the potential value of a SELDI-TOF-MS based classifier for discriminating between patients with a pelvic mass.</p> <p>Methods</p> <p>Our study design included a well-defined patient population, stringent protocols and an independent validation cohort. We compared serum samples of 53 ovarian cancer patients, 18 patients with tumors of low malignant potential, and 57 patients with a benign ovarian tumor on different ProteinChip arrays. In addition, from a subset of 84 patients, tumor tissues were collected and microdissection was used to isolate a pure and homogenous cell population.</p> <p>Results</p> <p>Diagonal Linear Discriminant Analysis (DLDA) and Support Vector Machine (SVM) classification on serum samples comparing cancer versus benign tumors, yielded models with a classification accuracy of 71-81% (cross-validation), and 73-81% on the independent validation set. Cancer and benign tissues could be classified with 95-99% accuracy using cross-validation. Tumors of low malignant potential showed protein expression patterns different from both benign and cancer tissues. Remarkably, none of the peaks differentially expressed in serum samples were found to be differentially expressed in the tissue lysates of those same groups.</p> <p>Conclusion</p> <p>Although SELDI-TOF-MS can produce reliable classification results in serum samples of ovarian cancer patients, it will not be applicable in routine patient care. On the other hand, protein profiling of microdissected tumor tissue may lead to a better understanding of oncogenesis and could still be a source of new serum biomarkers leading to novel methods for differentiating between different histological subtypes.</p

AEGIS-X: The Chandra Deep Survey of the Extended Groth Strip

We present the AEGIS-X survey, a series of deep Chandra ACIS-I observations of the Extended Groth Strip. The survey comprises pointings at 8 separate positions, each with nominal exposure 200ks, covering a total area of approximately 0.67 deg2 in a strip of length 2 degrees. We describe in detail an updated version of our data reduction and point source detection algorithms used to analyze these data. A total of 1325 band-merged sources have been found to a Poisson probability limit of 4e-6, with limiting fluxes of 5.3e-17 erg/cm2/s in the soft (0.5-2 keV) band and 3.8e-16 erg/cm2/s in the hard (2-10 keV) band. We present simulations verifying the validity of our source detection procedure and showing a very small, <1.5%, contamination rate from spurious sources. Optical/NIR counterparts have been identified from the DEEP2, CFHTLS, and Spitzer/IRAC surveys of the same region. Using a likelihood ratio method, we find optical counterparts for 76% of our sources, complete to R(AB)=24.1, and, of the 66% of the sources that have IRAC coverage, 94% have a counterpart to a limit of 0.9 microJy at 3.6 microns (m(AB)=23.8). After accounting for (small) positional offsets in the 8 Chandra fields, the astrometric accuracy of the Chandra positions is found to be 0.8 arcsec RMS, however this number depends both on the off-axis angle and the number of detected counts for a given source. All the data products described in this paper are made available via a public website.Comment: 17 pages, 9 figures. Accepted for publication in ApJS. Data products are available at http://astro.imperial.ac.uk/research/aegis

The X-Ray Zurich Environmental Study (X-ZENS). I. Chandra and XMM-Newton observations of active galactic nuclei in galaxies in nearby groups

We describe X-ray observations with Chandra and XMM-Newton of 18 galaxy groups (M_group ~ 1-6x10^13 Msolar, z~0.05) from the Zurich Environmental Study (ZENS). We aim to establish the frequency and properties, unaffected by host galaxy dilution and obscuration, of AGNs in central and satellite galaxy members, also as a function of halo-centric distance. X-ray point-source detections are reported for 22 of 177 observed galaxies, down to a limit of f_(0.5-8 keV) ~ 5x10^-15 erg cm^-2 s^-1, corresponding to a limiting luminosity of L_(0.5-8 keV)~3x10^40 erg s^-1. With the majority of the X-ray sources attributed to AGNs of low-to-moderate levels (L/L_Edd>~10^-4), we discuss the detection rate in the context of the occupation of AGNs to halos of this mass scale and redshift, and compare the structural/morphological properties between AGN-active and non-active galaxies of different rank and location within the group halos. We see a slight tendency for AGN hosts to have either relatively brighter/denser disks (or relatively fainter/diffuse bulges) than non-active galaxies of similar mass. At galaxy mass scales <10^11 Msolar, central galaxies appear to be a factor ~4 more likely to host AGNs than satellite galaxies of similar mass. This effect, coupled with the tendency for AGNs to reside in massive galaxies, explains the (weak) trend for AGNs to be preferentially found in the inner regions of groups, with no detectable trend with halo-centric distance in the frequency of AGNs within the satellite population. Finally, our data support other analyses in finding that the rate of decline with redshift of AGN activity in groups matches that of the global AGN population, indicating that either AGNs occur preferentially in groups, or that the evolution rate is independent of halo mass. These trends are of potential importance, and require X-ray coverage of a larger sample to be solidly confirmed.Comment: 18 pages, 13 figures, submitted to The Astrophysical Journal, this is a revised version that addresses the referee's comment

Investigating the occurrence of hierarchies of cyclicity in platform carbonates

Hierarchies of cyclicity have been described from a wide variety of carbonate platform strata and are assumed to be a consequence of Milankovitch-forced variations in accommodation, although descriptions of hierarchical strata, including ‘cycles’ and what they constitute, are typically qualitative, subjective, and in some cases difficult to reproduce. One reason for this is the lack of any detailed definition of what constitutes a hierarchy, as well as the implicit and largely untested nature of the assumptions underpinning most interpretations of hierarchical strata.In this study we aim to investigate the response of depositional systems if they were to behave in the way implied by sequence stratigraphic (hierarchical) models, to clearly state the assumptions of these models, and illustrate the consequences of these assumptions when they are employed in a simple, internally-consistent forward model with plausible parameters.We define hierarchies, in both the time-domain (chronostratigraphic) and thickness-domain (stratigraphic), as two or more high-frequency sequences (HFSs) in which there exists a repeated trend of decreasing high-frequency sequence thickness such that within a single low-frequency sequence (LFS) each high-frequency sequence is thinner than the previous sequence.Based on this definition, results from 110 000 numerical model runs suggest that ordered forcing via cyclical eustatic sea-level oscillations rarely results in an easily identifiable hierarchy of stacked cycles. Hierarchies measured in the chronostratigraphic time-domain occur in only 9% of model run cases, and in 15% of cases when measured in the thickness-domain, suggesting that vertical thickness trends are probably not a useful way to identify products of ordered periodic external forcing. Variability in relative forcing periodicity results in significant variation in both HFS and LFS thickness trends making accurate identification of hierarchy and any forcing controls from thickness data alone very difficult. Comparison between model results and outcrop sections suggests that hierarchies are often assumed to be present despite a lack of adequate supporting evidence and quantitative analysis of these sections suggests that they are not hierarchical in any meaningful sense

Observational constraints on the physics behind the evolution of AGN since z ~ 1

We explore the evolution with redshift of the rest-frame colours and space densities of AGN hosts (relative to normal galaxies) to shed light on the dominant mechanism that triggers accretion onto supermassive black holes as a function of cosmic time. Data from serendipitous wide-area XMM surveys of the SDSS footprint (XMM/SDSS, Needles in the Haystack survey) are combined with Chandra deep observations in the AEGIS, GOODS-North and GOODS-South to compile uniformly selected samples of moderate luminosity X-ray AGN [L_X(2-10keV) = 1e41-1e44erg/s] at redshifts 0.1, 0.3 and 0.8. It is found that the fraction of AGN hosted by red versus blue galaxies does not change with redshift. Also, the X-ray luminosity density associated with either red or blue AGN hosts remains nearly constant since z=0.8. X-ray AGN represent a roughly fixed fraction of the space density of galaxies of given optical luminosity at all redshifts probed by our samples. In contrast the fraction of X-ray AGN among galaxies of a given stellar mass decreases with decreasing redshift. These findings suggest that the same process or combination of processes for fueling supermassive black holes are in operation in the last 5 Gyrs of cosmic time. The data are consistent with a picture in which the drop of the accretion power during that period (1dex since z=0.8) is related to the decline of the space density of available AGN hosts, as a result of the evolution of the specific star-formation rate of the overall galaxy population. Scenarios which attribute the evolution of moderate luminosity AGN since z \approx 1 to changes in the suppermassive black hole accretion mode are not favored by our results.Comment: MNRAS accepted, 15 pages, 10 figure

The Mid-Infrared Properties of X-ray Sources

We combine the results of the Spitzer IRAC Shallow Survey and the Chandra XBootes Survey of the 8.5 square degrees Bootes field of the NOAO Deep Wide- Field Survey to produce the largest comparison of mid-IR and X-ray sources to date. The comparison is limited to sources with X-ray fluxes >8x10-15 erg cm-2s-1 in the 0.5-7.0 keV range and mid-IR sources with 3.6 um fluxes brighter than 18.4 mag (12.3 uJy). In this most sensitive IRAC band, 85% of the 3086 X-ray sources have mid-IR counterparts at an 80% confidence level based on a Bayesian matching technique. Only 2.5% of the sample have no IRAC counterpart at all based on visual inspection. Even for a smaller but a significantly deeper Chandra survey in the same field, the IRAC Shallow Survey recovers most of the X-ray sources. A majority (65%) of the Chandra sources detected in all four IRAC bands occupy a well-defined region of IRAC [3.6] - [4.5] vs [5.8] - [8.0] color-color space. These X-ray sources are likely infrared luminous, unobscured type I AGN with little mid-infrared flux contributed by the AGN host galaxy. Of the remaining Chandra sources, most are lower luminosity type I and type II AGN whose mid-IR emission is dominated by the host galaxy, while approximately 5% are either Galactic stars or very local galaxies.Comment: Accepted for publication in Ap

The XMM-LSS survey: the Class 1 cluster sample over the initial 5 square degrees and its cosmological modelling

We present a sample of 29 galaxy clusters from the XMM-LSS survey over an area of some 5deg2 out to a redshift of z=1.05. The sample clusters, which represent about half of the X-ray clusters identified in the region, follow well defined X-ray selection criteria and are all spectroscopically confirmed. For all clusters, we provide X-ray luminosities and temperatures as well as masses. The cluster distribution peaks around z=0.3 and T =1.5 keV, half of the objects being groups with a temperature below 2 keV. Our L-T(z) relation points toward self-similar evolution, but does not exclude other physically plausible models. Assuming that cluster scaling laws follow self-similar evolution, our number density estimates up to z=1 are compatible with the predictions of the concordance cosmology and with the findings of previous ROSAT surveys. Our well monitored selection function allowed us to demonstrate that the inclusion of selection effects is essential for the correct determination of the evolution of the L-T relation, which may explain the contradictory results from previous studies. Extensive simulations show that extending the survey area to 10deg2 has the potential to exclude the non-evolution hypothesis, but that constraints on more refined ICM models will probably be limited by the large intrinsic dispersion of the L-T relation. We further demonstrate that increasing the dispersion in the scaling laws increases the number of detectable clusters, hence generating further degeneracy [in addition to sigma8, Omega_m, L(M,z) and T(M,z)] in the cosmological interpretation of the cluster number counts. We provide useful empirical formulae for the cluster mass-flux and mass-count-rate relations as well as a comparison between the XMM-LSS mass sensitivity and that of forthcoming SZ surveys.Comment: Accepted for publication by MNRAS. Full resolution images as well as additional cluster data are available through a dedicated database at http://l3sdb.in2p3.fr:8080/l3sdb