89 research outputs found
Rare charm meson decays D->Pl^+l^- and c->ul^+l^- in SM and MSSM
We study the nine possible rare charm meson decays D->Pl^+l^-
(P=pi,K,eta,eta') using the Heavy Meson Chiral Lagrangians and find them to be
dominated by the long distance contributions. The decay D^+ -> pi^+l^+l^- with
the branching ratio 1*10^(-6) is expected to have the best chances for an early
experimental discovery. The short distance contribution in the five Cabibbo
suppressed channels arises via the c->ul^+l^- transition; we find that this
contribution is detectable only in the D->pi l^+l^- decay, where it dominates
the differential spectrum at high-q^2. The general Minimal Supersymmetric
Standard Model can enhance the c->ul^+l^- rate by up to an order of magnitude;
its effect on the D->Pl^+l^- rates is small since the c->ul^+l^- enhancement is
sizable in low-q^2 region, which is inhibited in the hadronic decay.Comment: 17 page
Evidence for a narrow dip structure at 1.9 GeV/c in diffractive photoproduction
A narrow dip structure has been observed at 1.9 GeV/c in a study of
diffractive photoproduction of the final state performed by the
Fermilab experiment E687.Comment: The data of Figure 6 can be obtained by downloading the raw data file
e687_6pi.txt. v5 (2nov2018): added Fig. 7, the 6 pion energy distribution as
requested by a reade
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age-and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to similar to 2.8M SNPs with BMI and WHRadjBMI in four strata (men 50y, women 50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR= 50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may providefurther insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.Peer reviewe
Optimisation of stirrer designs in a reverberation chamber
This paper describes an investigation into the key factors which contribute to an effective mode stirrer. The work concentrates on the lower frequency range, since all stirrers have poorer performance at low frequencies. The stirrer's shapes and sizes have been investigated, together with an optimization of the finer details in the stirrer's shape. The modeling of the mode stirred chamber has been performed using the transmission-line matrix (TLM) method. Software has been developed which, for each position of the rotating stirrer, builds the shape of the stirrer using thin, perfectly conducting boundaries. Results indicate that the design of the stirrer's basic shape has a small but significant impact on its performance. A genetic algorithm has been used to optimize certain parameters in the shape of the stirrer, and a fitness factor based on a free space model of the stirrer has been used. The free space model runs 1500 times faster than the model in the chamber. The optimization is shown to improve the stirrer's performance in three different sizes of chamber. Computer modeling has been verified by measurements performed in the chamber at the University of York
Solvent effects and molecular rearrangements during the reaction of Hauser bases with enolisable ketones: structural characterisation of [{ButC(=CH2)OMgBr.HMPA}2] and [MgBr2.(HMPA)2]
The Hauser base reagents Pri2NMgCl 1 and Pri2NMgBr 2 react with a variety of enolisable ketones to yield magnesium enolates. Attempts at isolation of these enolates when THF was present in the solvent media was unsuccessful, with the exclusive precipitation of the solvated dihalide salts (MgX2 · Sx, where X=Cl or Br and S=THF, TMEDA or HMPA). Using diethyl ether as solvent media and one molar equivalent of HMPA, the halomagnesium enolate compounds [{ButC(=CH2)OMgBr · HMPA}2] 3 and [Me2CHC(=CMe2)OMgBr · HMPA] 5 were isolated and identified. Both 3 and 5 precipitate as mixtures with the dihalide salt [MgBr2 · (HMPA)2] 4. X-ray crystallographic studies reveal 3 to be dimeric utilizing enolate bridges, whereas 4 is a simple monomer. A molecular-orbital theoretical study (HF/6-31G*) was conducted to determine the relative bridging abilities of several model anions. The enolate anion H(CH2=)CO− was determined to be a favoured bridge in preference to the halides F−, Cl− and Br−, which is consistent with the X-ray evidence. The amido anions Me2N−, (H3Si)2N− and (Me3Si)2N− are also calculated to be favoured over the chloride anion in three-coordinate dimer systems. This is contrary to the known structure of [{(Me3Si)2NMgCl · (Et2O)}2] 8 which bridges through the chloride atoms. The influence of solvent may be critical in determining which anion bridges. Solvent also plays a decisive role in the dismutation reaction of Hauser bases or halomagnesium enolates into their homoleptic components, similar to the Schlenk equilibrium for Grignard reagents
A proposed new definition and measurement of the shielding effect of equipment enclosures
This paper describes the rationale behind a new proposed measurement of the screening effect of an equipment enclosure that takes into account the contents of the enclosure. The method uses a set of representative contents for enclosures. The representative contents are equipped with surface field probes to measure the power entering the contents. The ratio of this power to the incident power density is used to derive a quantity with the dimensions of area, termed here the shielding aperture. The measurement technique is described and examples of measurements are given along with computed comparisons with the conventional shielding effectiveness of the enclosures used
Magnetic Resonance Imaging (MRI) Anatomy of the Ovine Lumbar Spine
Although the ovine spine is a useful research model for intervertebral disc pathology and vertebral surgery, there is little peer-reviewed information regarding the MRI anatomy of the ovine spine. To describe the lumbar spine MRI anatomy, 10 lumbar segments of cadaver ewes were imaged by 1.5-Tesla MR. Sagittal and transverse sequences were performed in T1 and T2 weighting (T1W, T2W), and the images were compared to gross anatomic sagittal and transverse sections performed through frozen spines. MRI was able to define most anatomic structures of the ovine spine in a similar way as can be imaged in humans. In both T1W and T2W, the signals of ovine IVDs were similar to those observed in humans. Salient anatomic features were identified: (1) a 2- to 3-mm linear zone of hypersignal was noticed on both extremities of the vertebral body parallel to the vertebral plates in sagittal planes; (2) the tendon of the crura of the diaphragm appeared as a hypointense circular structure between hypaxial muscles and the aorta and caudal vena cava; (3) dorsal and ventral longitudinal ligaments and ligamentum flavum were poorly imaged; (4) no ilio-lumbar ligament was present; (5) the spinal cord ended between S1-S2 level, and the peripheral white matter and central grey matter were easily distinguished on T1W and T2W images. This study provides useful reference images to researchers working with ovine models
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