The impact of the covid 19 pandemic on cancer diagnosis in a pathology service in southern Brazil

The Covid-19 pandemic has had a significant impact on people's lives. One of these impacts can be verified in the diagnosis of other diseases, especially cancer. Problem: What was the impact on the diagnosis of new cases of cancer in the region covered by a pathology service in southern Brazil during the pandemic? General objective: To evaluate whether there was a decrease in the number of cancer diagnoses in a pathology service in southern Brazil during the pandemic. Methodology: We analyzed the case reports carried out in the Laboratories of the Infolaudo Group, during the initial months of the pandemic (April and May 2020) and compared with the same months of 2019, in order to measure the impact of the pandemic on the diagnosis of cancer in a Pathology Service in southern Brazil. Results: Comparing the periods of April and May 2019 with the same period in 2020, a 34.2% decrease in pathological procedures was noticed. Some types of cancer, such as colon, esophagus, breast and prostate, had a significant decrease in diagnoses, being 19.7%, 45%, 18.2% and 37.7%, respectively. Conclusion: With the closure of many clinics and clinics in the early stages of the pandemic, there was a decrease in cancer diagnoses in the laboratories surveyed

El impacto de la pandemia de covid 19 en el diagnóstico de cáncer en un servicio de patología en el sur de Brasil

<p>La pandemia de Covid-19 ha tenido un impacto significativo en la vida de las personas. Uno de estos impactos se puede verificar en el diagnóstico de otras enfermedades, especialmente el cáncer. Problema: ¿Cuál fue el impacto en el diagnóstico de nuevos casos de cáncer en la región cubierta por un servicio de patología en el sur de Brasil durante la pandemia? Objetivo general: Evaluar si hubo una disminución en el número de diagnósticos de cáncer en un servicio de patología en el sur de Brasil durante la pandemia. Metodología: Analizamos los informes de casos realizados en los Laboratorios del Grupo Infolaudo, durante los primeros meses de la pandemia (abril y mayo de 2020) y comparados con los mismos meses de 2019, con el fin de medir el impacto de la pandemia en el diagnóstico de cáncer en un Servicio de Patología en el sur de Brasil. Resultados: Comparando los períodos de abril y mayo de 2019 con el mismo período de 2020, se observó una disminución del 34,2% en los procedimientos patológicos. Algunos tipos de cáncer, como colon, esófago, mama y próstata, tuvieron una disminución significativa en los diagnósticos, siendo 19.7%, 45%, 18.2% y 37.7%, respectivamente. Conclusión: Con el cierre de muchas clínicas y clínicas en las primeras etapas de la pandemia, hubo una disminución en los diagnósticos de cáncer en los laboratorios encuestados.</p><p>The Covid-19 pandemic has had a significant impact on people’s lives. One of these impacts can be verified in the diagnosis of other diseases, especially cancer. Problem: What was the impact on the diagnosis of new cases of cancer in the region covered by a pathology service in southern Brazil during the pandemic? General objective: To evaluate whether there was a decrease in the number of cancer diagnoses in a pathology service in southern Brazil during the pandemic. Methodology: We analyzed the case reports carried out in the Laboratories of the Infolaudo Group, during the initial months of the pandemic (April and May 2020) and compared with the same months of 2019, in order to measure the impact of the pandemic on the diagnosis of cancer in a Pathology Service in southern Brazil. Results: Comparing the periods of April and May 2019 with the same period in 2020, a 34.2% decrease in pathological procedures was noticed. Some types of cancer, such as colon, esophagus, breast and prostate, had a significant decrease in diagnoses, being 19.7%, 45%, 18.2% and 37.7%, respectively. Conclusion: With the closure of many clinics and clinics in the early stages of the pandemic, there was a decrease in cancer diagnoses in the laboratories surveyed.</p&gt

L'impatto della pandemia di covid 19 sulla diagnosi di cancro in un servizio di patologia nel sud del Brasile

<p>La pandemia di Covid-19 ha avuto un impatto significativo sulla vita delle persone. Uno di questi impatti può essere verificato nella diagnosi di altre malattie, in particolare il cancro. Problema: qual è stato l'impatto sulla diagnosi di nuovi casi di cancro nella regione coperta da un servizio di patologia nel sud del Brasile durante la pandemia? Obiettivo generale: valutare se c'è stata una diminuzione del numero di diagnosi di cancro in un servizio di patologia nel sud del Brasile durante la pandemia. Metodologia: Abbiamo analizzato i case report effettuati nei Laboratori del Gruppo Infolaudo, durante i primi mesi della pandemia (aprile e maggio 2020) e confrontati con gli stessi mesi del 2019, al fine di misurare l'impatto della pandemia sulla diagnosi di cancro in un servizio di patologia nel sud del Brasile. Risultati: Confrontando i periodi di aprile e maggio 2019 con lo stesso periodo del 2020, è stata notata una diminuzione del 34,2% delle procedure patologiche. Alcuni tipi di cancro, come il colon, l'esofago, il seno e la prostata, hanno avuto una significativa diminuzione delle diagnosi, essendo rispettivamente del 19,7%, 45%, 18,2% e 37,7%. Conclusione: con la chiusura di molte cliniche e cliniche nelle prime fasi della pandemia, c'è stata una diminuzione delle diagnosi di cancro nei laboratori esaminati.</p><p>The Covid-19 pandemic has had a significant impact on people’s lives. One of these impacts can be verified in the diagnosis of other diseases, especially cancer. Problem: What was the impact on the diagnosis of new cases of cancer in the region covered by a pathology service in southern Brazil during the pandemic? General objective: To evaluate whether there was a decrease in the number of cancer diagnoses in a pathology service in southern Brazil during the pandemic. Methodology: We analyzed the case reports carried out in the Laboratories of the Infolaudo Group, during the initial months of the pandemic (April and May 2020) and compared with the same months of 2019, in order to measure the impact of the pandemic on the diagnosis of cancer in a Pathology Service in southern Brazil. Results: Comparing the periods of April and May 2019 with the same period in 2020, a 34.2% decrease in pathological procedures was noticed. Some types of cancer, such as colon, esophagus, breast and prostate, had a significant decrease in diagnoses, being 19.7%, 45%, 18.2% and 37.7%, respectively. Conclusion: With the closure of many clinics and clinics in the early stages of the pandemic, there was a decrease in cancer diagnoses in the laboratories surveyed.</p&gt

Karyotypic changes and diversification time in Epinephelidae groupers (Perciformes). Implications on reproductive isolation

Groupers (Epinephelidae and Serranidae) have attracted special attention to fish farming, and their species offer good opportunities for successful hybridizations. Cytogenetic data allow a better understanding of the role of karyotypic diversification in the acquisition of post-zygotic reproductive isolation (RI). Thus, chromosomal analyses were performed on E. striatus (Caribbean Sea), E. coioides and E. tauvina (Indo-Pacific Region), using standard procedures and mapping of six repetitive DNA classes by the in situ hybridization. The three species have 2n=48 chromosomes. The karyotypes of E. coioides and E. striatus are composed only of acrocentric chromosomes (FN=48), while E. tauvina has 8 submetacentric chromosomes (FN=56). Heterochromatin has a preferential centromeric distribution, and the microsatellite repeats are dispersed throughout the chromosomes of all species. The 18S and 5S rDNA sites are unique but show a colocalization arrangement in E. tauvina and E. striatus. The chromosomal organization suggests that the three species still maintain a significant amount of syntenic regions. The range of the karyotype divergence and the RI levels showed low, but goes turn proportionally greater in relation to the divergence time between the parental species. The slow acquisition of postzygotic RI is consistent with the high karyotype homogeneity presented by Epinephelidae family

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved