442 research outputs found
Transitions in a West African labour market : the role of social networks
Dans cet article, nous analysons le rôle des réseaux sociaux dans la dynamique d'un marché du travail en Afrique de l'Ouest, en nous intéressant aux transitions du chômage vers l'emploi, de l'emploi salarié vers l’emploi indépendant et enfin de l’emploi indépendant vers l’emploi salarié. Les données d’une enquête originale que nous utilisons permettent d’appréhender les réseaux sociaux dans trois de leurs dimensions, à savoir sa structure, la force des liens et des ressources intégrées dans le réseau, et d’analyser les effets différenciés de chacune de ces dimensions sur ces transitions. Ces données, collectées à Ouagadougou en 2009, rassemblent les biographies professionnelles de 2000 ménages et sont représentatives à l’échelle de la ville. En nous appuyant sur des modèles de risques proportionnels, nous constatons que les réseaux sociaux ont un effet significatif sur la dynamique des travailleurs et que cet effet diffère selon le type de transition et la dimension considérée du réseau social. La taille du réseau semble joué un rôle mineur au regard des deux autres dimensions. Des liens forts jouent un rôle stabilisateur en limitant les grandes transitions. Leur effet négatif sur les transitions est renforcé quand ces liens forts sont combinés à un niveau élevé de ressources du réseau
Vocational education, on-the-job training and labour market integration of young workers in urban West Africa
Background paper prepared for the Education for All Global Monitoring Report 2012 “Youth and skills: Putting education to work”Using surveys covering seven West African economic capitals in the early 2000s, this paper describes
the labour market integration of youth with regard to their level of formal education and to the type of
vocational training they received. We particularly focus on the informal sector and look at activity
rates, unemployment, earnings, job quality and small firm performance in order to identify the key
features of youth labour market integration. To our knowledge, these features of Africa’s labour
markets are rarely documented at a sectoral level using representative samples of urban areas. The
overall results suggest that the youth are the most disadvantaged in terms of unemployment, access to
the formal sector, and earnings. We provide some evidence that vocational education might be a good
instrument for integrating the formal sector and that it is often more profitable than general education
in terms of earnings and firm performance, especially at higher levels of schooling. Generally,
education, especially at high levels, provides a substantial growth in earnings in informal jobs in most
of the cities studied. Regarding the incidence of vocational education and training (VET), the main
form observed is traditional apprenticeship. Overall, young workers without any formal VET are the
more disadvantaged in terms of working conditions, while workers who benefited from a traditional
apprenticeship in a small firm occupy an intermediate position. Apprenticeship training for young
workers seems to be fairly prevalent in the informal sector, but the associated working conditions are
bad, and kinship ties seem to be there a crucial channel for training access
A Wearable Sensor Network for Gait Analysis: A 6-Day Experiment of Running Through the Desert
International audienceThis paper presents a new system for analysis of walking and running gaits. The system is based on a network of wireless nodes with various types of embedded sensors. It has been designed to allow long-term recording in outdoor environments and was tested during the 2010 "Sultan Marathon des Sables" desert race. A runner was fitted with the sensory network for six days of the competition. Although technical problems have limited the amount of data recorded, the experiment was nevertheless suc- cessful: the system did not interfere with the runner, who finished with a high ranking, the concept was validated and high quality data were ac- quired. It should be noted that the loss of some of the measurements was mainly due to problems with the cable connectors between the nodes and batteries. In this paper, we describe the technical aspects of the system developed, the experimental conditions under which it was validated, and give examples of the data obtained with some preliminary processing
Evolution of Total and Integrated HIV-1 DNA and Change in DNA Sequences in Patients with Sustained Plasma Virus Suppression
AbstractBlood samples from patients with plasma HIV-1 RNA <20 copies/ml for more than 2 years were studied. Significant decreases in total and integrated HIV-1 DNA were observed during the first 15 months of suppressive therapy before the concentrations became stable. Clonal analysis of HIV-1 pol demonstrated that the proportions of resistance mutations in DNA sequences after 2 years were lower than those in baseline DNA and RNA sequences. The changes in the clonal composition of HIV-1 env populations in three patients with evidence of changes in HIV-1 pol populations indicated a shift from predominantly R5-like viruses to predominantly X4-like viruses in two patients and the persistence of predominantly X4-like viruses in the third. Our analyses indicate the reemergence of ancestral sequences from long-lived cells or the residual production of wild-type virus from anatomic sites with limited access to antiretroviral drugs and the preferential infection of cells expressing CXCR4
Comparison of Matrix Pencil Extracted Features in Time Domain and in Frequency Domain for Radar Target Classification
Feature extraction is a challenging problem in radar target identification. In this paper, we propose a new approach of feature extraction by using Matrix Pencil Method in Frequency Domain (MPMFD). The proposed method takes into account not only the magnitude of the signal, but also its phase, so that all the physical characteristics of the target will be considered. With this method, the separation between the early time and the late time is not necessary. The proposed method is compared to Matrix Pencil Method in Time Domain (MPMTD). The methods are applied on UWB backscattered signal from three canonical targets (thin wire, sphere, and cylinder). MPMFD is applied on a complex field (real and imaginary parts of the signal). To the best of our knowledge, this comparison and the reconstruction of the complex electromagnetic field by MPMFD have not been done before. We show the effect of the two extraction methods on the accuracy of three different classifiers: Naïve bayes (NB), K-Nearest Neighbor (K-NN), and Support Vector Machine (SVM). The results show that the accuracy of classification is better when using extracted features by MPMFD with SVM
Baryon Acoustic Oscillations in the Ly{\alpha} forest of BOSS DR11 quasars
We report a detection of the baryon acoustic oscillation (BAO) feature in the
flux-correlation function of the Ly{\alpha} forest of high-redshift quasars
with a statistical significance of five standard deviations. The study uses
137,562 quasars in the redshift range from the Data Release
11 (DR11) of the Baryon Oscillation Spectroscopic Survey (BOSS) of SDSS-III.
This sample contains three times the number of quasars used in previous
studies. The measured position of the BAO peak determines the angular distance,
and expansion rate, , both on a scale set by the sound
horizon at the drag epoch, . We find
and
where . The optimal
combination, is determined with a precision of
. For the value , consistent with the CMB power
spectrum measured by Planck, we find
and . Tests with mock
catalogs and variations of our analysis procedure have revealed no systematic
uncertainties comparable to our statistical errors. Our results agree with the
previously reported BAO measurement at the same redshift using the
quasar-Ly{\alpha} forest cross-correlation. The auto-correlation and
cross-correlation approaches are complementary because of the quite different
impact of redshift-space distortion on the two measurements. The combined
constraints from the two correlation functions imply values of and
that are, respectively, 7% low and 7% high compared to the
predictions of a flat CDM cosmological model with the best-fit Planck
parameters. With our estimated statistical errors, the significance of this
discrepancy is .Comment: Accepted for publication in A&A. 17 pages, 18 figure
The Baryon Oscillation Spectroscopic Survey of SDSS-III
The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the
scale of baryon acoustic oscillations (BAO) in the clustering of matter over a
larger volume than the combined efforts of all previous spectroscopic surveys
of large scale structure. BOSS uses 1.5 million luminous galaxies as faint as
i=19.9 over 10,000 square degrees to measure BAO to redshifts z<0.7.
Observations of neutral hydrogen in the Lyman alpha forest in more than 150,000
quasar spectra (g<22) will constrain BAO over the redshift range 2.15<z<3.5.
Early results from BOSS include the first detection of the large-scale
three-dimensional clustering of the Lyman alpha forest and a strong detection
from the Data Release 9 data set of the BAO in the clustering of massive
galaxies at an effective redshift z = 0.57. We project that BOSS will yield
measurements of the angular diameter distance D_A to an accuracy of 1.0% at
redshifts z=0.3 and z=0.57 and measurements of H(z) to 1.8% and 1.7% at the
same redshifts. Forecasts for Lyman alpha forest constraints predict a
measurement of an overall dilation factor that scales the highly degenerate
D_A(z) and H^{-1}(z) parameters to an accuracy of 1.9% at z~2.5 when the survey
is complete. Here, we provide an overview of the selection of spectroscopic
targets, planning of observations, and analysis of data and data quality of
BOSS.Comment: 49 pages, 16 figures, accepted by A
The Ninth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-III Baryon Oscillation Spectroscopic Survey
The Sloan Digital Sky Survey III (SDSS-III) presents the first spectroscopic
data from the Baryon Oscillation Spectroscopic Survey (BOSS). This ninth data
release (DR9) of the SDSS project includes 535,995 new galaxy spectra (median
z=0.52), 102,100 new quasar spectra (median z=2.32), and 90,897 new stellar
spectra, along with the data presented in previous data releases. These spectra
were obtained with the new BOSS spectrograph and were taken between 2009
December and 2011 July. In addition, the stellar parameters pipeline, which
determines radial velocities, surface temperatures, surface gravities, and
metallicities of stars, has been updated and refined with improvements in
temperature estimates for stars with T_eff<5000 K and in metallicity estimates
for stars with [Fe/H]>-0.5. DR9 includes new stellar parameters for all stars
presented in DR8, including stars from SDSS-I and II, as well as those observed
as part of the SDSS-III Sloan Extension for Galactic Understanding and
Exploration-2 (SEGUE-2).
The astrometry error introduced in the DR8 imaging catalogs has been
corrected in the DR9 data products. The next data release for SDSS-III will be
in Summer 2013, which will present the first data from the Apache Point
Observatory Galactic Evolution Experiment (APOGEE) along with another year of
data from BOSS, followed by the final SDSS-III data release in December 2014.Comment: 9 figures; 2 tables. Submitted to ApJS. DR9 is available at
http://www.sdss3.org/dr
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
Understanding the genetic and nongenetic determinants of tumor protein 53 (TP53)-mutation-driven clonal evolution and subsequent transformation is a crucial step toward the design of rational therapeutic strategies. Here we carry out allelic resolution single-cell multi-omic analysis of hematopoietic stem/progenitor cells (HSPCs) from patients with a myeloproliferative neoplasm who transform to TP53-mutant secondary acute myeloid leukemia (sAML). All patients showed dominant TP53 ‘multihit’ HSPC clones at transformation, with a leukemia stem cell transcriptional signature strongly predictive of adverse outcomes in independent cohorts, across both TP53-mutant and wild-type (WT) AML. Through analysis of serial samples, antecedent TP53-heterozygous clones and in vivo perturbations, we demonstrate a hitherto unrecognized effect of chronic inflammation, which suppressed TP53 WT HSPCs while enhancing the fitness advantage of TP53-mutant cells and promoted genetic evolution. Our findings will facilitate the development of risk-stratification, early detection and treatment strategies for TP53-mutant leukemia, and are of broad relevance to other cancer types
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