Programas e intervenciones educativas ofrecidas al personal farmacéutico para mejorar la prestación de los servicios asistenciales farmacéuticos: una revisión estructurada

Objetivo: Describir los programas y las intervenciones educativas ofrecidas al personal farmacéutico para mejorar la prestación de los servicios asistenciales farmacéuticos, y los métodos utilizados para evaluar la efectividad de estos programas. Métodos: Se realizó una revisión estructurada utilizando la base de datos PubMed/Medline entre de 2007 y 2019, sobre el desarrollo, la descripción, la evaluación del impacto, la efectividad o la comparación de una intervención educativa, un entrenamiento específico o un programa educativo dirigido al personal farmacéutico de farmacias comunitarias (ambulatorias) y/o hospitalarias. Resultados: En total 1070 referencias bibliográficas fueron identificadas, además, se incluyeron 26 referencias identificadas por otras fuentes, y se seleccionaron 90 artículos para su revisión y análisis. Se encontró que el 70% (63) de los estudios fueron desarrollados en países desarrollados, principalmente en Estados Unidos, Australia, Canadá e Inglaterra. El 67% (60) de los estudios se realizaron a nivel ambulatorio, el 10% (9) a nivel hospitalario, y el 23% (21) en ambos contextos. Se encontró que las intervenciones fueron clasificadas en tres categorías: entrenamientos específicos (41%), programas de Educación Continua (43%) y de Desarrollo Profesional Continuo (16%). La metodología o métodos de suministro de la intervención más común fue la presencial en el 72% (65) de los estudios, seguido de metodologías apoyadas de herramientas virtuales en el 28% (25) y en el 11% (10) de los estudios combinaron métodos presenciales y virtuales. El tiempo de duración de las intervenciones educativas vario entre menos de 1 hora a 120 horas. Conclusión: Se describen los programas y las intervenciones educativas ofrecidas al personal farmacéutico principalmente para mejorar sus competencias laborales y la prestación de los servicios asistenciales farmacéuticos, además de los métodos utilizados para evaluar la efectividad de las intervenciones educativas.  Objective: To describe the educational programs and interventions offered to pharmaceutical personnel to improve the delivery of pharmaceutical healthcare services, and the methods used to evaluate the effectiveness of the programs Methods: A structured review was performed using the PubMed / Medline database from 2007 to 2019. Results: In total, 1070 bibliographic references were identified; besides, 26 references identified by other sources were included, and 90 articles were selected for review and analysis. It was found that 70% (63) of the studies were developed in developed countries, mainly in the United States, Australia, Canada, and England. 67% (60) of the studies were carried out at the outpatient level, 10% (9) at the hospital level, and 23% (21) in both contexts. The interventions were found to be classified into three categories: specific settings (41%), Continuing Education (43%), and Continuing Professional Development (16%) programs. The most common methodology or delivery methods for the intervention were face-to-face in 72% (65) of the studies, followed by methodologies supported by virtual tools in 28% (25) and 11% (10) of the studies combined face-to-face and virtual methods. The duration of the educational interventions ranged from less than 1 hour to 120 hours. Conclusion: The educational programs and interventions offered to the pharmaceutical personnel are described mainly to improve their labor competencies and the provision of pharmaceutical healthcare services, in addition to the methods used to evaluate the effectiveness of the educational intervention.    &nbsp

Revisión, diseño y construcción de un instrumento de medición para evaluar las competencias laborales del personal farmacéutico ambulatorio

 Objetivo: identificar y seleccionar las directrices y recomendaciones sobre las competencias laborales que requiere el personal farmacéutico ambulatorio, y construir un instrumento para su medición. Métodos: Se realizó una revisión estructurada en dos fases: a) se revisaron y seleccionaron las funciones/dominios, los criterios de desempeño (habilidades y actitudes), los conocimientos, los marcos de competencias establecidas a nivel internacional, y los instrumentos de medición reportados en la literatura; y b) se identificaron las competencias laborales necesarias de acuerdo con la normatividad colombiana y con los procesos de los Establecimientos Farmacéuticos ambulatorios (droguerías y farmacias-droguerías). Finalmente, se construyó el instrumento de medición por un panel de expertos. Resultados: Se identificaron las competencias laborales establecidas por las organizaciones de regulación internacional. Se revisaron 993 artículos que reportaban la medición y evaluación de las competencias, seleccionándose y analizándose 9 referencias. Se analizaron los marcos de competencias de diferentes países. Se analizaron las regulaciones en Colombia sobre el tema. El instrumento construido contiene 101 competencias distribuidas en los siguientes componentes: a) suministro de cuidados al paciente; b) personales; c) solución de problemas; y d) gestión y organización directrices y recomendaciones internacionales, además, la normatividad colombiana para identificar las competencias laborales que requiere el personal farmacéutico para el correcto funcionamiento de los Establecimientos Farmacéuticos ambulatorios, y partir de esto, se construye un instrumento de medición para evaluarlas.Introduction: The measurement and evaluation of labor competencies, in outpatient pharmacy staff, must combine aspects related to knowledge (who knows), skills (as it does) and attitudes (in what way it does). Objective: Identify and select the guidelines and recommendations on labor competencies required by outpatient pharmacy staff and build an instrument for their measurement. Methodology: A structured review was carried out in two phases: a) the functions/ domains, performance criteria (skills and attitudes), knowledge, competency frameworks established internationally, and measurement instruments reported were reviewed and selected in the literature; and b) the necessary labor competencies were identified in accordance with Colombian regulations and with the processes of the outpatient Pharmaceutical Establishments (drugstores and pharmacies-drugstores). Finally, the measuring instrument was built by a panel of experts. Results: Labor competencies established by international regulation organizations. were identified. A total of 993 articles were reviewed that reported the measurement and evaluation of competencies, selecting and analyzing 9 references. Competency frameworks from different countries were analyzed. The regulations in Colombia on the subject were analyzed. The constructed instrument contains 101 competencies distributed in the following components: a) provision of patient care; b) personal; c) troubleshooting; and d) management and organization. Conclusion: The international guidelines and recommendations were reviewed and analyzed, in addition, the Colombian regulations to identify the labor competencies required by the pharmacy staff for the correct functioning of the outpatient Pharmaceutical Establishments, and from this, an instrument was built of measurement to evaluate them

Guía de actuación farmacéutica en pacientes con esquizofrenia

Revisado por: Ramón Eduardo Lopera LoperaLa guía de actuación farmacéutica en pacientes con esquizofrenia pretende favorecer la vinculación y aportes del farmacéutico al grupo de atención integral al paciente con Esquizofrenia, con la finalidad de contribuir al uso efectivo y seguro a los medicamentos antipsicóticos y, con ello, al logro de los mejores resultados terapéuticos posibles. Se compilan a lo largo de estos cinco capítulos, conceptos teóricosy prácticos organizados de manera sencilla y gráfica para que, el profesional farmacéutico integre el equipo de atención ambulatoria u hospitalaria de los pacientes con enfermedades mentales, integre a su trabajo tanto elementos clínicos como terapéuticos que le permitan contribuir a la obtención de los mejores resultados posibles en la solución de este problema de salud, mediante la identificación, prevención y solución de los problemas de proceso y resultado de los medicamentos y, con ello, de los problemas de efectividad y seguridad de la farmacoterapia

Production of He-4 and (4) in Pb-Pb collisions at root(NN)-N-S=2.76 TeV at the LHC

Results on the production of He-4 and (4) nuclei in Pb-Pb collisions at root(NN)-N-S = 2.76 TeV in the rapidity range vertical bar y vertical bar <1, using the ALICE detector, are presented in this paper. The rapidity densities corresponding to 0-10% central events are found to be dN/dy4(He) = (0.8 +/- 0.4 (stat) +/- 0.3 (syst)) x 10(-6) and dN/dy4 = (1.1 +/- 0.4 (stat) +/- 0.2 (syst)) x 10(-6), respectively. This is in agreement with the statistical thermal model expectation assuming the same chemical freeze-out temperature (T-chem = 156 MeV) as for light hadrons. The measured ratio of (4)/He-4 is 1.4 +/- 0.8 (stat) +/- 0.5 (syst). (C) 2018 Published by Elsevier B.V.Peer reviewe

Habitabilidad y política de vivienda

En esta obra, en la que participan destacados investigadores y profesores, dedicados al estudio de la problemática habitacional se presentan diferentes análisis que permiten conocer cuales son las condiciones de habitabilidad y las características de la actual política de vivienda de México. En sus capítulos se abordan los principales desafíos que enfrentan las familias mexicanas para acceder a una vivienda digna y decorosa y cuales son los retos económicos, políticos, territoriales, arquitectónicos, ambientales, financieros y culturales de las formas de producción habitacional en México y en otros países, en el marco de una sociedad global

Multiplicity dependence of light (anti-)nuclei production in p–Pb collisions at sNN=5.02 TeV

The measurement of the deuteron and anti-deuteron production in the rapidity range −1 < y < 0 as a function of transverse momentum and event multiplicity in p–Pb collisions at √sNN = 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dx and via their time-of- flight. Their production in p–Pb collisions is compared to pp and Pb–Pb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and approaching those observed in Pb–Pb collisions at high multiplicities. The mean transverse particle momenta are extracted from the deuteron spectra and the values are similar to those obtained for p and particles. Thus, deuteron spectra do not follow mass ordering. This behaviour is in contrast to the trend observed for non-composite particles in p–Pb collisions. In addition, the production of the rare 3He and 3He nuclei has been studied. The spectrum corresponding to all non-single diffractive p-Pb collisions is obtained in the rapidity window −1 < y < 0 and the pT-integrated yield dN/dy is extracted. It is found that the yields of protons, deuterons, and 3He, normalised by the spin degeneracy factor, follow an exponential decrease with mass number

Longitudinal and azimuthal evolution of two-particle transverse momentum correlations in Pb-Pb collisions at sNN=2.76TeV\sqrt{s_{\rm{NN}}} = 2.76 TeV

This paper presents the first measurements of the charge independent (CI) and charge dependent (CD) two-particle transverse momentum correlators G2CI and G2CD in Pb–Pb collisions at sNN=2.76TeV by the ALICE collaboration. The two-particle transverse momentum correlator G2 was introduced as a measure of the momentum current transfer between neighboring system cells. The correlators are measured as a function of pair separation in pseudorapidity (Δ η ) and azimuth (Δ φ ) and as a function of collision centrality. From peripheral to central collisions, the correlator G2CI exhibits a longitudinal broadening while undergoing a monotonic azimuthal narrowing. By contrast, G2CD exhibits a narrowing along both dimensions. These features are not reproduced by models such as HIJING and AMPT. However, the observed narrowing of the correlators from peripheral to central collisions is expected to result from the stronger transverse flow profiles produced in more central collisions and the longitudinal broadening is predicted to be sensitive to momentum currents and the shear viscosity per unit of entropy density η/s of the matter produced in the collisions. The observed broadening is found to be consistent with the hypothesized lower bound of η/s and is in qualitative agreement with values obtained from anisotropic flow measurements.This paper presents the first measurements of the charge independent (CI) and charge dependent (CD) two-particle transverse momentum correlators $G_{2}^{\rm CI}$ and $G_{2}^{\rm CD}$ in Pb--Pb collisions at \sqrt{s_{\text{NN}}} = 2.76\;\text{\TeVe} by the ALICE collaboration. The two-particle transverse momentum correlator $G_{2}$ was introduced as a measure of the momentum current transfer between neighbouring system cells. The correlators are measured as a function of pair separation in pseudorapidity ($\Delta \eta$) and azimuth ($\Delta \varphi$) and as a function of collision centrality. From peripheral to central collisions, the correlator $G_{2}^{\rm CI}$ exhibits a longitudinal broadening while undergoing a monotonic azimuthal narrowing. By contrast, $G_{2}^{\rm CD}$ exhibits a narrowing along both dimensions. These features are not reproduced by models such as HIJING and AMPT. However, the observed narrowing of the correlators from peripheral to central collisions is expected to result from the stronger transverse flow profiles produced in more central collisions and the longitudinal broadening is predicted to be sensitive to momentum currents and the shear viscosity per unit of entropy density $\eta/s$ of the matter produced in the collisions. The observed broadening is found to be consistent with the hypothesized lower bound of $\eta/s$ and is in qualitative agreement with values obtained from anisotropic flow measurements

Inclusive J/ψ\psi production in Xe–Xe collisions at sNN\sqrt{s_{\rm NN}} = 5.44 TeV

Inclusive J/$\psi$ production is studied in Xe-Xe interactions at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\rm NN}}= 5.44$ TeV, using the ALICE detector at the CERN LHC. The J/$\psi$ meson is reconstructed via its decay into a muon pair, in the centre-of-mass rapidity interval $2.5<y<4$ and down to zero transverse momentum. In this Letter, the nuclear modification factors $R_{\rm AA}$ for inclusive J/$\psi$, measured in the centrality range 0-90% as well as in the centrality intervals 0-20% and 20-90% are presented. The $R_{\rm AA}$ values are compared to previously published results for Pb-Pb collisions at $\sqrt{s_{\rm NN}}= 5.02$ TeV and to the calculation of a transport model. A good agreement is found between Xe-Xe and Pb-Pb results as well as between data and the model

Real-time data processing in the ALICE High Level Trigger at the LHC

International audienceAt the Large Hadron Collider at CERN in Geneva, Switzerland, atomic nuclei are collided at ultra-relativistic energies. Many final-state particles are produced in each collision and their properties are measured by the ALICE detector. The detector signals induced by the produced particles are digitized leading to data rates that are in excess of 48 GB/s. The ALICE High Level Trigger (HLT) system pioneered the use of FPGA- and GPU-based algorithms to reconstruct charged-particle trajectories and reduce the data size in real time. The results of the reconstruction of the collision events, available online, are used for high level data quality and detector-performance monitoring and real-time time-dependent detector calibration. The online data compression techniques developed and used in the ALICE HLT have more than quadrupled the amount of data that can be stored for offline event processing

Anisotropic flow in Xe-Xe collisions at sNN=5.44\mathbf{\sqrt{s_{\rm{NN}}} = 5.44} TeV

The first measurements of anisotropic flow coefficients vn for mid-rapidity charged particles in Xe–Xe collisions at sNN=5.44 TeV are presented. Comparing these measurements to those from Pb–Pb collisions at sNN=5.02 TeV, v2 is found to be suppressed for mid-central collisions at the same centrality, and enhanced for central collisions. The values of v3 are generally larger in Xe–Xe than in Pb–Pb at a given centrality. These observations are consistent with expectations from hydrodynamic predictions. When both v2 and v3 are divided by their corresponding eccentricities for a variety of initial state models, they generally scale with transverse density when comparing Xe–Xe and Pb–Pb, with some deviations observed in central Xe–Xe and Pb–Pb collisions. These results assist in placing strong constraints on both the initial state geometry and medium response for relativistic heavy-ion collisions