8,241 research outputs found
Mild solutions of local non-Lipschitz neutral stochastic partial functional differential equations
This paper studies the existence and uniqueness of a mild solution for a neutral stochastic partial functional differential equation with in-nite delays using Caratheodory conditions and also the exponential stability of the moments of a mild solutions well as its sample paths.An example is provided to illustrate the obtained result
Envejecimiento demográfico en México. Evaluación de los datos censales por edad y sexo, 1970-2000
El artículo analiza las modificaciones en la estructura de edad, y enfatiza sobre la plausibilidad de la hipótesis de sobreestimación de la población en edades avanzadas, a partir de la evaluación de la calidad de la información censal en cuanto a la declaración de la edad de dicha población en México a nivel de entidad federativa. Este último aspecto se cubre a partir de la aplicación del índice de Whipple modificado a la población adulta mayor proveniente de los censos de población de 1970 a 2000. Los resultados obtenidos muestran la existencia de errores en la declaración de edades de dicha población, así como la inconsistencia entre la proporción de dicha población y la etapa de la transición demográfica en la que se ubica en algunos estados, lo cual aporta elementos adiconales acerca de la posible sobrestimación de la población en edades avanzadas.El artículo analiza las modificaciones en la estructura de edad, y enfatiza sobre la plausibilidad de la hipótesis de sobreestimación de la población en edades avanzadas, a partir de la evaluación de la calidad de la información censal en cuanto a la declaración de la edad de dicha población en México a nivel de entidad federativa. Este último aspecto se cubre a partir de la aplicación del índice de Whipple modificado a la población adulta mayor proveniente de los censos de población de 1970 a 2000. Los resultados obtenidos muestran la existencia de errores en la declaración de edades de dicha población, así como la inconsistencia entre la proporción de dicha población y la etapa de la transición demográfica en la que se ubica en algunos estados, lo cual aporta elementos adiconales acerca de la posible sobrestimación de la población en edades avanzadas
Studying the role of the strawberry Fra protein family in the flavonoid metabolism during fruit ripening
Strawberry fruits are highly appreciated worldwide due to their pleasant flavor and aroma and to the health benefits associated to their consumption. An important part of these properties is due to their content in secondary metabolites, especially phenolic compounds, of which flavonoids are the most abundant in the strawberry fruit. Although the flavonoid biosynthesis pathway is uncovered, little is known about its regulation.
The strawberry Fra a (Fra) genes constitute a large family of homologs of the major birch pollen allergen Bet v 1 and for which no equivalents exist in Arabidopsis. Our group has shown that Fra proteins are involved in the formation of colored compounds in strawberries (Muñoz et al., 2010), which mainly depends on the production of certain flavonoids; that they are structurally homologs to the PYR/PYL/RCAR Arabidopsis ABA receptor, and that they are able to bind flavonoids (Casañal et al., 2013). With these previous results, our working hypothesis is that the Fra proteins are involved in the regulation of the flavonoids pathway. They would mechanistically act as the ABA receptor, binding a protein interactor and a ligand to regulate a signaling cascade and/or act as molecular carriers.
The main objective of this research is to characterize the Fra family in strawberry and gain insight into their role in the flavonoid metabolism.
By RNAseq expression analysis in ripening fruits we have identified transcripts for 10 members of the Fra family. Although expressed in all tissues analyzed, each family member presents a unique pattern of expression, which suggests functional specialization for each Fra protein.
Then, our next approach was to identify the proteins that interact with Fras and their ligands to gain knowledge on the role that these proteins play in the flavonoids pathway.
To identify the interacting partners of Fras we have performed a yeast two hybrid (Y2H) screening against cDNA libraries of strawberry fruits at the green and red stages. A protein that shares a 95% homology to the Heat stress transcription factor A-4-C like of Fragaria vesca (HSA4C) interacts specifically with Fra1 and not with other family members, which suggests functional diversification of Fra proteins in specific signaling pathways. The Y2H screening is not yet saturated, so characterization of other interacting proteins with other members of the Fra family will shed light on the functional diversity within this gene family.
This research will contribute to gain knowledge on how the flavonoid pathway, and hence, the fruit ripening, is regulated in strawberry; an economically important crop but for which basic research is still very limited.
References:
Muñoz, C, et al. (2010). The Strawberry Fruit Fra a Allergen Functions in Flavonoid Biosynthesis. Molecular Plant, 3(1): 113–124.
Casañal, A, et al (2013). The Strawberry Pathogenesis-related 10 (PR-10) Fra a Proteins Control Flavonoid Biosynthesis by Binding Metabolic Intermediates. Journal of Biological Chemistry, 288(49): 35322–35332.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Energy harvesting from vehicular traffic over speed bumps: A review
Energy used by vehicles to slow down in areas of limited speed is wasted. A traffic energy-harvesting device (TEHD) is capable of harvesting vehicle energy when passing over a speed bump. This paper presents a classification of the different technologies used in the existing TEHDs. Moreover, an estimation of the energy that could be harvested with the different technologies and their cost has been elaborated. The energy recovered with these devices could be used for marking and lighting of roads in urban areas, making transportation infrastructures more sustainable and environmentally friendly
An Intelligent Traction Control for Motorcycles
The appearance of anti-lock braking systems (ABS) and traction control systems
(TCS) have been some of the most major developments in vehicle safety. These systems have
been evolving since their origin, always keeping the same objective, by using increasingly
sophisticated algorithms and complex brake and torque control architectures. The aim of this
work is to develop and implement a new control model of a traction control system to be
installed on a motorcycle, regulating the slip in traction and improving dynamic performance of
two-wheeled vehicles. This paper presents a novel traction control algorithm based on the use of
Artificial Neural Networks (ANN) and Fuzzy Logic. An ANN is used to estimate the optimal
slip of the surface the vehicle is moving on. A fuzzy logic control block, which makes use of the
optimal slip provided by the ANN, is developed to control the throttle position. Two control
blocks have been tuned. The first control block has been tuned according to the experience of an
expert operator. The second one has been optimized using Evolutionary Computation (EC).
Simulation shows that the use of EC can improve the fuzzy logic based control algorithm,
obtaining better results than those produced with the control tuned only by experience.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Revision of the family Carabodidae (Acari, Oribatida) VII. Redefinition of the genus Malgasodes; redescription of M. curvisetus Mahunka, 2000; and complementary description of M. hungarorum Mahunka, 2010. Phylogenetic relationships between Malgasodes, Bovicarabodes, Afticarabodes, Congocepheus and Cavaecarabodes are discussed
The genus Malgasodes is redefined; the type species M. curvisetus Mahunka, 2000, is redescribed by meansof studies using optic and Scanning Electron Microsopy (SEM), and a complementary description of M.hungarorum Mahunka, 2000 is included. Comparison of genera Malgasodes Mahunka, 2000, Bovicarabodes Fernandez, Theron, Rollard, 2013a, Cavaecarabodes Fernandez, Theron, Rollard, Rodriguez Castillo,2014, Afticarabodes Fernandez, Theron, Rollard, 2013b, and Congocepheus Balogh, 1958 is made. Problems concerning chaetotaxy, regressive evolution and neotrichy are explained and phylogenetic relationships between Malgasodes, Bovicarabodes, Afticarabodes, Congocepheus and Cavaecarabodes are discussed.Fil: Fernández, Néstor Alfredo. North-West University. Research Unit for Environmental Sciences and Management; Sudáfrica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; ArgentinaFil: Theron, Pieter. North-West University. Research Unit for Environmental Sciences and Management; SudáfricaFil: Rollard, Christine. Muséum National d; FranciaFil: Castillo, Elio Rodrigo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Biología Subtropical. Universidad Nacional de Misiones. Instituto de Biología Subtropical; Argentin
The chaos of hypertension guidelines for chronic kidney disease patients
Three major guidelines deal with blood pressure thresholds and targets for antihypertensive drug therapy in chronic kidney disease (CKD) patients: the 2012 Kidney Disease: Improving Global Outcomes Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease; the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults; and the 2018 ESC/ESH Guidelines for the Management of Arterial Hypertension. However, a careful reading of the three guidelines leaves the practicing physician confused about the definition of CKD, how hypertension and secondary hypertension should be diagnosed in CKD patients and what the blood pressure thresholds, targets and compelling indications of antihypertensive drug therapy should be for this population. Current guidelines refer to different CKD populations and propose different definitions of hypertension, different thresholds to initiate antihypertensive therapy in CKD patients and different BP targets compelling antihypertensive drug use. The different bodies producing guidelines should work together towards a unified definition of CKD, a unified concept of hypertension and unified BP thresholds and targets for hypertensive drug therapy for CKD patients. Otherwise they risk promoting confusion and therapeutic nihilism among physicians and patientsResearch by the authors was supported by FIS CP14/00133, PI16/02057, PI18/01366, PI19/00588, PI19/00815, DTS18/00032, ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071), ISCIII-RETIC REDinREN RD016/0009 Fondos FEDER, FRIAT, Sociedad Española de Nefrología, Comunidad de Madrid B2017/BMD-3686 CIFRA2-C
Experiences of foreign nurses in Finland : barriers
The field of nursing has seen a rising demand in the past decades. Nursing immigration and migration over the decades has been phenomenal. There is increased number of nurses emigrating from developing countries to developed countries in search of better working environments, better working motivations, better skills and so fort (Tregunno et al 2009).
The research is contracted by KYKY. The KYKY project was developed by Salo region adult education center and Turku University of applied science. KYKY stands for Kansainvälistyvät työyhteisöt osaaviksi ja kilpailukykyisiksi, which translates as (International work community to be competent and competitive). The objective of the project is to help sustain and retain international qualified skilled and competitive workers for example in the social and healthcare field in Salo. Southwest Finland Centre for Economic Development, the European Social Fund (ESR), Turku University of Applied sciences and Salo region adult education center funds the project.
The aim of the research is to find the experiences of foreign nurses in Finland. The purpose is to create a piece of work that will be available to future aspirant of nursing education in Finland, workers, teachers and all interested.
The results indicates that Foreign nurses experience cultural discrimination, language, and communication barriers amongs many others
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