Eingruppierungsunterschiede von Frauen und Männern beim Staat als Arbeitgeber

"In diesem Beitrag wird untersucht, welche Eingruppierungsunterschiede zwischen Männern und Frauen beim Staat als Arbeitgeber im Jahre 1980 bestanden haben. Das empirische Material liefert die Beschäftigtenstichprobe aus dem "Paderborner Datensatz". Verwendet werden zwei Regressionsmodelle mit den Humankapital-Variablen Geschlecht, Schulbildung, Alter und Betriebszugehörigkeitsdauer, die Methode der Komponentenzerlegung sowie ein Index für geschlechtsspezifische Segregation. Die Analyse zeigt, daß Frauen insgesamt gesehen im Durchschnitt niedriger als Männer eingruppiert sind, wobei die Differenz nur zu rund 33% auf Unterschiede in der Humankapitalausstattung zurückgeführt werden kann. Bei einer Aufgliederung in die Statusgruppen Beamte, Angestellte und Arbeiter wird der Befund der Benachteiligung von Frauen für jede dieser drei Gruppen - wenn auch in unterschiedlichem Ausmaße - bestätigt. Dieses Bild ändert sich jedoch stark, wenn innerhalb der Statusgruppen weiter nach Laufbahngruppen bzw. Diensten unterschieden wird: In einer Mehrheit dieser Gruppen sind keine Eingruppierungsbenachteiligungen von Frauen festzustellen, so daß die o.a. Befunde nur auf Benachteiligungen in folgenden Gruppen zurückzuführen sind: Beamtinnen im höheren Dienst, weibliche Angestellte im mittleren Dienst sowie un- und angelernte Arbeiterinnen. Die Unterschiede sind in der Gruppe der un- und angelernten Arbeiterinnen und Arbeiter am stärksten ausgeprägt, bei den Beamtinnen und Beamten des einfachen Dienstes am geringsten. Die Ergebnisse dürfen wegen der Begrenztheit der Datenbasis, der ausschließlichen Berücksichtigung von Humankapitalvariablen sowie der im Prinzip bekannten Besonderheiten der Einstellungspraxis staatlicher Arbeitgeber (Bedeutung der Schulbildung als Zugangsvoraussetzung) nicht überinterpretiert werden. (Autorenreferat)staatlicher Sektor, Frauen, Männer, Eingruppierung, Einkommensunterschied

Modificações microestruturais e tribológicas nos açosferramenta AISI H13 e DIN X100CrMoV 8-1-1 produzidas por nitretação a plasma

The tool-steels AISI H13 and DIN X100CrMoV 8-1-1, which are used for different applications, were plasma nitrided in a low concentration nitrogen atmosphere at 500°C in order to increase the wear resistance. Then, metallurgical properties of these steels before and after nitriding were evaluated, and wear tests were also performed. The results demonstrated that plasma nitriding successfully increased the wear resistance on both steels. This study also demonstrated how the modified properties contributed in this way. Key words: plasma nitriding, wear, H13, DIN X100CrMoV 8-1-1.Os acos-ferramenta AISI H13 e DIN X100CrMoV 8-1- 1, de características e aplicações distintas, foram nitretados a plasma em atmosfera de baixa concentração de nitrogênio a 500°C com o objetivo de incrementar a resistência ao desgaste. Em seguida, foi feita uma avaliação de propriedades metalúrgicas nos aços antes e após a nitretacão, e também foram feitos ensaios de desgaste. Os resultados demonstraram que a nitretacão a plasma foi eficiente em aumentar a resistência ao desgaste dos dois aços. O estudo também demonstrou como as propriedades modificadas contribuíram neste sentido. Palavras-chave: nitretacão a plasma, desgaste, H13, DIN X100CrMoV 8-1-1

Hochspezialisierte ambulante Versorgung in Krankenhäusern: eine empirische Abschätzung von Kosten, Erlösen und mögliche Strategien

'Ambulante Behandlungen im Krankenhaus werden vom Gesetzgeber zunehmend gefördert. Angesichts möglicher Kostenunterdeckungen und Mengenbudgetierungen ist die Wahl der besten Strategie für Krankenhäuser bisher unklar. Auf der Basis von 16.171 an 6 Hochschulkliniken in Deutschland prospektiv dokumentierten Konsultationen in Ermächtigungsambulanzen (3.219 Konsultationen) und Hochschulambulanzen (12.952 Konsultationen) wurden von den Autoren Kosten und Erlöse gegenüber gestellt. Der Deckungsgrad lag je nach Ambulanzart bei 27% bis 29% bezogen auf die Gesamtkosten (44% bis 47% bezogen auf die Primärkosten). Da diese Unterdeckung zu einer Unterversorgung der Bevölkerung bei spezialisierter ambulanter Behandlung führen kann, ist auch aus gesundheitspolitischer Sicht eine Überprüfung der Finanzierung sinnvoll.' (Autorenreferat)'The delivery of ambulatory care in hospitals is broadened by legislative actions in Germany. However, best strategies for hospitals are unclear due to consideration of costs, reimbursements and budgeting. We included 16,171 prospectively documented consultations from six university hospitals in Germany. The ratio of reimbursement to total cost was 27% to 29%, concerning to the type of ambulatory care. (44% to 47% concerning to variable costs). This financial deficit could cause a shortage of highly specialized ambulatory services. Health policy interventions might be necessary.' (author's abstract)

Ground validation of oceanic snowfall detection in satellite climatologies during LOFZY

A thorough knowledge of global ocean precipitation is an indispensable prerequisite for the understanding of the water cycle in the global climate system. However, reliable detection of precipitation over the global oceans, especially of solid precipitation, remains a challenging task. This is true for both, passive microwave remote sensing and reanalysis based model estimates. The optical disdrometer ODM 470 is a ground validation instrument capable of measuring rain and snowfall on ships even under high wind speeds. It was used for the first time over the Nordic Seas during the LOFZY 2005 campaign. A dichotomous verification of precipitation occurrence resulted in a perfect correspondence between the disdrometer, a precipitation detector and a shipboard observer's log. The disdrometer data is further point-to-area collocated against precipitation from the satellite based Hamburg Ocean Atmosphere Parameters and fluxes from Satellite data (HOAPS) climatology. HOAPS precipitation turns out to be overall consistent with the disdrometer data resulting in a detection accuracy of 0.96. The collocated data comprises light precipitation events below 1 mm h–1. Therefore two LOFZY case studies with high precipitation rates are presented that indicate plausible HOAPS satellite precipitation rates. Overall, this encourages longer term measurements of ship-to-satellite collocated precipitation in the near future

Simulating the global distribution of nitrogen isotopes in the ocean

We present a new nitrogen isotope model incorporated into the three-dimensional ocean component of a global Earth system climate model designed for millennial timescale simulations. The model includes prognostic tracers for the two stable nitrogen isotopes, 14N and 15N, in the nitrate (NO3−), phytoplankton, zooplankton, and detritus variables of the marine ecosystem model. The isotope effects of algal NO3− uptake, nitrogen fixation, water column denitrification, and zooplankton excretion are considered as well as the removal of NO3− by sedimentary denitrification. A global database of δ15NO3− observations is compiled from previous studies and compared to the model results on a regional basis where sufficient observations exist. The model is able to qualitatively and quantitatively reproduce many of the observed patterns such as high subsurface values in water column denitrification zones and the meridional and vertical gradients in the Southern Ocean. The observed pronounced subsurface minimum in the Atlantic is underestimated by the model presumably owing to too little simulated nitrogen fixation there. Sensitivity experiments reveal that algal NO3− uptake, nitrogen fixation, and water column denitrification have the strongest effects on the simulated distribution of nitrogen isotopes, whereas the effect from zooplankton excretion is weaker. Both water column and sedimentary denitrification also have important indirect effects on the nitrogen isotope distribution by reducing the fixed nitrogen inventory, which creates an ecological niche for nitrogen fixers and, thus, stimulates additional N2 fixation in the model. Important model deficiencies are identified, and strategies for future improvement and possibilities for model application are outlined

Systematic, early rhythm control strategy for atrial fibrillation in patients with or without symptoms:the EAST-AFNET 4 trial

AIMS: Clinical practice guidelines restrict rhythm control therapy to patients with symptomatic atrial fibrillation (AF). The EAST-AFNET 4 trial demonstrated that early, systematic rhythm control improves clinical outcomes compared to symptom-directed rhythm control. METHODS AND RESULTS: This prespecified EAST-AFNET 4 analysis compared the effect of early rhythm control therapy in asymptomatic patients (EHRA score I) to symptomatic patients. Primary outcome was a composite of death from cardiovascular causes, stroke, or hospitalization with worsening of heart failure or acute coronary syndrome, analyzed in a time-to-event analysis. At baseline, 801/2633 (30.4%) patients were asymptomatic [mean age 71.3 years, 37.5% women, mean CHA(2)DS(2)-VASc score 3.4, 169/801 (21.1%) heart failure]. Asymptomatic patients randomized to early rhythm control (395/801) received similar rhythm control therapies compared to symptomatic patients [e.g. AF ablation at 24 months: 75/395 (19.0%) in asymptomatic; 176/910 (19.3%) symptomatic patients, P = 0.672]. Anticoagulation and treatment of concomitant cardiovascular conditions was not different between symptomatic and asymptomatic patients. The primary outcome occurred in 79/395 asymptomatic patients randomized to early rhythm control and in 97/406 patients randomized to usual care (hazard ratio 0.76, 95% confidence interval [0.6; 1.03]), almost identical to symptomatic patients. At 24 months follow-up, change in symptom status was not different between randomized groups (P = 0.19). CONCLUSION: The clinical benefit of early, systematic rhythm control was not different between asymptomatic and symptomatic patients in EAST-AFNET 4. These results call for a shared decision discussing the benefits of rhythm control therapy in all patients with recently diagnosed AF and concomitant cardiovascular conditions (EAST-AFNET 4; ISRCTN04708680; NCT01288352; EudraCT2010-021258-20)

Iron availability limits the ocean nitrogen inventory stabilizing feedbacks between marine denitrification and nitrogen fixation

Author Posting. © American Geophysical Union, 2007. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Global Biogeochemical Cycles 21 (2007): GB2001, doi:10.1029/2006GB002762.Recent upward revisions in key sink/source terms for fixed nitrogen (N) in the oceans imply a short residence time and strong negative feedbacks involving denitrification and N fixation to prevent large swings in the ocean N inventory over timescales of a few centuries. We tested the strength of these feedbacks in a global biogeochemical elemental cycling (BEC) ocean model that includes water column denitrification and an explicit N fixing phytoplankton group. In the northern Indian Ocean and over longer timescales in the tropical Atlantic, we find strong stabilizing feedbacks that minimize changes in marine N inventory over timescales of ∼30–200 years. In these regions high atmospheric dust/iron inputs lead to phosphorus limitation of diazotrophs, and thus a tight link between N fixation and surface water N/P ratios. Maintenance of the oxygen minimum zones in these basins depends on N fixation driven export. The stabilizing feedbacks in other regions are significant but weaker owing to iron limitation of the diazotrophs. Thus Fe limitation appears to restrict the ability of N fixation to compensate for changes in denitrification in the current climate, perhaps leading the oceans to lose fixed N. We suggest that iron is the ultimate limiting nutrient leading to nitrogen being the proximate limiting nutrient over wide regions today. Iron stress was at least partially alleviated during more dusty, glacial times, leading to a higher marine N inventory, increased export production, and perhaps widespread phosphorus limitation of the phytoplankton community. The increased efficiency of the biological pump would have contributed to the glacial drawdown in atmospheric CO2.This work was supported by grants from the U.S. National Science Foundation (OCE-0222033 and OCE-0452972). Computations supported by Earth System Modeling Facility (NSF ATM-0321380) and by the Climate Simulation Laboratory at the National Center for Atmospheric Research

Glacial-interglacial modulation of the marine nitrogen cycle by high-latitude O2 supply to the global thermocline

Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Paleoceanography 19 (2004): PA4007, doi:10.1029/2003PA001000.An analysis of sedimentary nitrogen isotope records compiled from widely distributed marine environments emphasizes the global synchrony of denitrification changes and provides evidence for a strong temporal coupling of these variations to changes in nitrogen fixation as previously inferred. We explain the global coherence of these records by a simple physical control on the flux of dissolved oxygen to suboxic zones and the coupling to fixation via the supply of phosphorus to diazotrophs in suitable environments. According to our hypothesis, lower glacial-stage sea surface temperature increased oxygen solubility, while stronger winds in high-latitude regions enhanced the rate of thermocline ventilation. The resultant colder, rapidly flushed thermocline lessened the spatial extent of denitrification and, consequently, N fixation. During warm periods, sluggish circulation of warmer, less oxygen rich thermocline waters caused expansion of denitrification zones and a concomitant increase in N fixation. Local fluctuations in export productivity would have modulated this global signal.Financial support for this work was provided by the Natural Sciences and Engineering Research Council of Canada and by a WHOI postdoctoral fellowship to MK

The endothelial-enriched lncRNA LINC00607 mediates angiogenic function

Long non-coding RNAs (lncRNAs) can act as regulatory RNAs which, by altering the expression of target genes, impact on the cellular phenotype and cardiovascular disease development. Endothelial lncRNAs and their vascular functions are largely undefined. Deep RNA-Seq and FANTOM5 CAGE analysis revealed the lncRNA LINC00607 to be highly enriched in human endothelial cells. LINC00607 was induced in response to hypoxia, arteriosclerosis regression in non-human primates, post-atherosclerotic cultured endothelial cells from patients and also in response to propranolol used to induce regression of human arteriovenous malformations. siRNA knockdown or CRISPR/Cas9 knockout of LINC00607 attenuated VEGF-A-induced angiogenic sprouting. LINC00607 knockout in endothelial cells also integrated less into newly formed vascular networks in an in vivo assay in SCID mice. Overexpression of LINC00607 in CRISPR knockout cells restored normal endothelial function. RNA- and ATAC-Seq after LINC00607 knockout revealed changes in the transcription of endothelial gene sets linked to the endothelial phenotype and in chromatin accessibility around ERG-binding sites. Mechanistically, LINC00607 interacted with the SWI/SNF chromatin remodeling protein BRG1. CRISPR/Cas9-mediated knockout of BRG1 in HUVEC followed by CUT&RUN revealed that BRG1 is required to secure a stable chromatin state, mainly on ERG-binding sites. In conclusion, LINC00607 is an endothelial-enriched lncRNA that maintains ERG target gene transcription by interacting with the chromatin remodeler BRG1 to ultimately mediate angiogenesis